50 Matching Annotations
  1. Jul 2025
  2. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  3. Jun 2025
  4. www.nature.com www.nature.com
    PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
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    nature.com/articles/s41419-025-07782-y
  5. May 2025
  6. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12082889/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ankrd1 Promotes Lamellipodia Formation and Cell Motility via Interaction with Talin-1 in Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12072362/
  9. Apr 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225006248-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12053632/
  11. Mar 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Hypoxia inducible factor-1α drives cancer resistance to cuproptosis
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    sciencedirect.com/science/article/pii/S1535610825000674
  13. Feb 2025
  14. aacrjournals.org aacrjournals.org
    Hypertension promotes the proliferation and migration of ccRCC cells by downregulation of TIMP3 in tumor endothelial cells through the miR-21-5p/TGFBR2/P38/EGR1 axis
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    aacrjournals.org/mcr/article/21/1/62/711796/Hypertension-Promotes-the-Proliferation-and
  15. www.sciencedirect.com www.sciencedirect.com
    Rhodoquinone carries electrons in the mammalian electron transport chain
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    sciencedirect.com/science/article/pii/S009286742401420X
  16. Jan 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11662763/
  18. Aug 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  20. www.cell.com www.cell.com
    Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
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    cell.com/cell-reports/fulltext/S2211-1247(24)00678-8
  21. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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    transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
  22. Jul 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11215406/
  24. Jun 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166694/
  26. May 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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    sciencedirect.com/science/article/pii/S235239642400197X
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
  29. Apr 2024
  30. www.sciencedirect.com www.sciencedirect.com
    TFE3/PI3K/Akt/mTOR axis in renal cell carcinoma affects tumor microenvironment
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    sciencedirect.com/science/article/pii/S0002944024001226
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984980/
  32. Mar 2024
  33. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  34. Feb 2024
  35. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma
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    jeccr.biomedcentral.com/articles/10.1186/s13046-022-02467-2
  36. Dec 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10690095/
  38. www.mdpi.com www.mdpi.com
    Silver Nanoparticles (AgNPs) as Enhancers of Everolimus and Radiotherapy Sensitivity on Clear Cell Renal Cell Carcinoma
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    mdpi.com/2076-3921/12/12/2051
  39. www.sciencedirect.com www.sciencedirect.com
    circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis
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    sciencedirect.com/science/article/pii/S0141813023052376
  40. Oct 2023
  41. link.springer.com link.springer.com
    Preclinical Pharmacokinetics and Translational Pharmacokinetic/Pharmacodynamic Modeling of M8891, a Potent and Reversible Inhibitor of Methionine Aminopeptidase 2
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    link.springer.com/article/10.1007/s11095-023-03611-z
  42. Sep 2023
  43. www.mdpi.com www.mdpi.com
    Basement Membrane-Associated lncRNA Risk Model Predicts Prognosis and Guides Clinical Treatment in Clear Cell Renal Cell Carcinoma
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    mdpi.com/2227-9059/11/10/2635
  44. Jun 2023
  45. www.nature.com www.nature.com
    Insulin receptor expression to predict resistance to axitinib and elucidation of the underlying molecular mechanism in metastatic renal cell carcinoma
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    nature.com/articles/s41416-023-02325-8
  46. www.nature.com www.nature.com
    piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination
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    nature.com/articles/s12276-023-01010-3
  47. May 2023
  48. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    sciencedirect.com/science/article/pii/S2211124722008750
  49. Mar 2023
  50. www.sciencedirect.com www.sciencedirect.com
    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    sciencedirect.com/science/article/pii/S0021925823002636
  51. Feb 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress‐related tumorigenicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9899607/
  53. Jan 2023
  54. www.sciencedirect.com www.sciencedirect.com
    RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer
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    sciencedirect.com/science/article/pii/S221112472300027X
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977765/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial
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    ncbi.nlm.nih.gov/pmc/articles/PMC9401491/
  57. Dec 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness
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    sciencedirect.com/science/article/pii/S1535610822005657
  59. 52.53.155.43 52.53.155.43
    mcr-22-0089-html.html
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    52.53.155.43/107272860f790f84446fdab08d39b0eb9cf7e5e0/mcr-22-0089-html.html
  60. Oct 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector
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    ncbi.nlm.nih.gov/pmc/articles/PMC9521038/
  62. May 2022
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8568653/
  64. Apr 2022
  65. www.sciencedirect.com www.sciencedirect.com
    An in vivo orthotopic serial passaging model for a metastatic renal cancer study
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    sciencedirect.com/science/article/pii/S2666166722001861
  66. Aug 2021
  67. elifesciences.org elifesciences.org
    Untitled document
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    elifesciences.org/articles/30224
  68. Jul 2021
  69. www.sciencedirect.com www.sciencedirect.com
    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    sciencedirect.com/science/article/pii/S1550413119303171
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA HOTAIR promotes cell migration by upregulating insulin growth factor–binding protein 2 in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC5607269/
  71. www.sciencedirect.com www.sciencedirect.com
    Stratification of clear cell renal cell carcinoma patients to facilitate drug repositioning
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    sciencedirect.com/science/article/pii/S2589004221006908
  72. May 2021
  73. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12931
  74. Apr 2021
  75. www.sciencedirect.com www.sciencedirect.com
    HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins
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    sciencedirect.com/science/article/pii/S2451945620303846
  76. www.sciencedirect.com www.sciencedirect.com
    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
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    sciencedirect.com/science/article/pii/S1097276521000988
  77. Mar 2021
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncometabolite L‐2‐hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7986127/
  79. Feb 2021
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12
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    ncbi.nlm.nih.gov/pmc/articles/PMC6985262/
  81. Nov 2018
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5773178/