66 Matching Annotations
  1. Last 7 days
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    USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2211124726004067
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ERMP1 Exerts Tumor‐Suppressive Functions in KIRC by Inhibiting PI3K/AKT Signaling and Remodeling the Immune Microenvironment: A Pan‐Cancer Analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13057433/
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    Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression
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    sciencedirect.com/science/article/pii/S2451945626001054
  6. Mar 2026
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    Targeting the ferritinophagy-lysosome axis as a therapeutic vulnerability in gastroenteropancreatic neuroendocrine tumors
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    sciencedirect.com/science/article/pii/S2666379126001126
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    1-s2.0-S2589004226005730-main-html.html
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  9. Feb 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12881505/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZNF395 is a Hypoxia-Responsive Regulator of Mitochondrial Glutaminolysis in Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12875648/
  12. Jan 2026
  13. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Lipid Droplet-Localized Spindle Apparatus Coiled-Coil Protein 1 Regulates Lipid Droplet Distribution
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511960
  14. Dec 2025
  15. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression
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    sciencedirect.com:5037/science/article/pii/S1097276525009402
  16. Nov 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KDM6A deficiency promotes tumor progression and resistance to cabozantinib treatment in clear cell renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12586554/
  18. Oct 2025
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TCIRG1 as a Novel Prognostic Biomarker Triggering Immune Infiltration in Renal Clear Cell Carcinoma: An Integrative Study of Single-Cell and Bulk Data
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    onlinelibrary.wiley.com/doi/full/10.1155/humu/1839494
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    STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012008
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    Intestinal Lachnospiraceae bacterium-derived propionate inhibits the progression of clear cell renal cell carcinoma
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    sciencedirect.com/science/article/pii/S2666379125004835
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    ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice
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    sciencedirect.com/science/article/pii/S2666379125004732
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated single-cell and bulk transcriptome analysis revealed high plasticity subpopulation and promising diagnosis model for clear cell renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12487111/
  24. Sep 2025
  25. www.biorxiv.org www.biorxiv.org
    Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling
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    biorxiv.org/content/10.1101/2025.08.31.673338v1
  26. Jul 2025
  27. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  28. Jun 2025
  29. www.nature.com www.nature.com
    PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
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    nature.com/articles/s41419-025-07782-y
  30. May 2025
  31. www.science.org www.science.org
    CD8+ T cell–derived CD40L mediates noncanonical cytotoxicity in CD40-expressing cancer cells
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    science.org/doi/10.1126/sciadv.adr9331
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12082889/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ankrd1 Promotes Lamellipodia Formation and Cell Motility via Interaction with Talin-1 in Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12072362/
  34. Apr 2025
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    pmc.ncbi.nlm.nih.gov/articles/PMC12053632/
  36. Mar 2025
  37. www.sciencedirect.com www.sciencedirect.com
    Hypoxia inducible factor-1α drives cancer resistance to cuproptosis
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    sciencedirect.com/science/article/pii/S1535610825000674
  38. Feb 2025
  39. aacrjournals.org aacrjournals.org
    Hypertension promotes the proliferation and migration of ccRCC cells by downregulation of TIMP3 in tumor endothelial cells through the miR-21-5p/TGFBR2/P38/EGR1 axis
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    aacrjournals.org/mcr/article/21/1/62/711796/Hypertension-Promotes-the-Proliferation-and
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    Rhodoquinone carries electrons in the mammalian electron transport chain
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    sciencedirect.com/science/article/pii/S009286742401420X
  41. Jan 2025
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated machine learning reveals the role of tryptophan metabolism in clear cell renal cell carcinoma and its association with patient prognosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11662763/
  43. Aug 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  45. www.cell.com www.cell.com
    Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma
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    cell.com/cell-reports/fulltext/S2211-1247(24)00678-8
  46. transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com
    iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer
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    transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
  47. Jul 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11215406/
  49. Jun 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amiloride reduces fructosamine-3-kinase expression to restore sunitinib sensitivity in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166694/
  51. May 2024
  52. www.sciencedirect.com www.sciencedirect.com
    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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    sciencedirect.com/science/article/pii/S235239642400197X
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
  54. Apr 2024
  55. www.sciencedirect.com www.sciencedirect.com
    TFE3/PI3K/Akt/mTOR axis in renal cell carcinoma affects tumor microenvironment
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    sciencedirect.com/science/article/pii/S0002944024001226
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
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    ncbi.nlm.nih.gov/pmc/articles/PMC10984980/
  57. Mar 2024
  58. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  59. Feb 2024
  60. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma
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    jeccr.biomedcentral.com/articles/10.1186/s13046-022-02467-2
  61. Dec 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PERK Inhibition by HC-5404 Sensitizes Renal Cell Carcinoma Tumor Models to Antiangiogenic Tyrosine Kinase Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10690095/
  63. www.mdpi.com www.mdpi.com
    Silver Nanoparticles (AgNPs) as Enhancers of Everolimus and Radiotherapy Sensitivity on Clear Cell Renal Cell Carcinoma
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    mdpi.com/2076-3921/12/12/2051
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    circWSB1 promotes tumor progression in ccRCC via circWSB1/miR-182-5p/WSB1 axis
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    sciencedirect.com/science/article/pii/S0141813023052376
  65. Oct 2023
  66. link.springer.com link.springer.com
    Preclinical Pharmacokinetics and Translational Pharmacokinetic/Pharmacodynamic Modeling of M8891, a Potent and Reversible Inhibitor of Methionine Aminopeptidase 2
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    link.springer.com/article/10.1007/s11095-023-03611-z
  67. Sep 2023
  68. www.mdpi.com www.mdpi.com
    Basement Membrane-Associated lncRNA Risk Model Predicts Prognosis and Guides Clinical Treatment in Clear Cell Renal Cell Carcinoma
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    mdpi.com/2227-9059/11/10/2635
  69. Jun 2023
  70. www.nature.com www.nature.com
    Insulin receptor expression to predict resistance to axitinib and elucidation of the underlying molecular mechanism in metastatic renal cell carcinoma
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    nature.com/articles/s41416-023-02325-8
  71. www.nature.com www.nature.com
    piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination
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    nature.com/articles/s12276-023-01010-3
  72. May 2023
  73. www.sciencedirect.com www.sciencedirect.com
    KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
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    sciencedirect.com/science/article/pii/S2211124722008750
  74. Mar 2023
  75. www.sciencedirect.com www.sciencedirect.com
    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    sciencedirect.com/science/article/pii/S0021925823002636
  76. Feb 2023
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress‐related tumorigenicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9899607/
  78. Jan 2023
  79. www.sciencedirect.com www.sciencedirect.com
    RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer
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    sciencedirect.com/science/article/pii/S221112472300027X
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977765/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial
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    ncbi.nlm.nih.gov/pmc/articles/PMC9401491/
  82. Dec 2022
  83. www.sciencedirect.com www.sciencedirect.com
    Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness
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    sciencedirect.com/science/article/pii/S1535610822005657
  84. 52.53.155.43 52.53.155.43
    mcr-22-0089-html.html
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  85. Oct 2022
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient and reversible Cas13d-mediated knockdown with an all-in-one lentivirus-vector
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    ncbi.nlm.nih.gov/pmc/articles/PMC9521038/
  87. May 2022
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8568653/
  89. Apr 2022
  90. www.sciencedirect.com www.sciencedirect.com
    An in vivo orthotopic serial passaging model for a metastatic renal cancer study
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    sciencedirect.com/science/article/pii/S2666166722001861
  91. Aug 2021
  92. elifesciences.org elifesciences.org
    Untitled document
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    elifesciences.org/articles/30224
  93. Jul 2021
  94. www.sciencedirect.com www.sciencedirect.com
    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    sciencedirect.com/science/article/pii/S1550413119303171
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA HOTAIR promotes cell migration by upregulating insulin growth factor–binding protein 2 in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC5607269/
  96. www.sciencedirect.com www.sciencedirect.com
    Stratification of clear cell renal cell carcinoma patients to facilitate drug repositioning
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    sciencedirect.com/science/article/pii/S2589004221006908
  97. May 2021
  98. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12931
  99. Apr 2021
  100. www.sciencedirect.com www.sciencedirect.com
    HSP90 Inhibition Enhances Cancer Immunotherapy by Modulating the Surface Expression of Multiple Immune Checkpoint Proteins
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    sciencedirect.com/science/article/pii/S2451945620303846
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    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
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    sciencedirect.com/science/article/pii/S1097276521000988
  102. Mar 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncometabolite L‐2‐hydroxyglurate directly induces vasculogenic mimicry through PHLDB2 in renal cell carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7986127/
  104. Feb 2021
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 mutation in renal clear cell carcinoma suppress autophagy via regulation of ATG12
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    ncbi.nlm.nih.gov/pmc/articles/PMC6985262/
  106. Nov 2018
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5773178/