119 Matching Annotations
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    Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression
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    sciencedirect.com/science/article/pii/S2451945626001054
  3. Apr 2026
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70500
  5. Mar 2026
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    A novel MST1-targeting kinsenoside derivative K30 attenuates acute kidney injury by restoring mitochondrial homeostasis
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    sciencedirect.com/science/article/pii/S2211383526001590
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    Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra-Targeted Tumor α-Therapy
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    onlinelibrary.wiley.com/doi/full/10.1002/exp2.70144
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  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imidazole Propionate Induces Kidney Damage by Activating the ROS‐NLRP3 Signaling Pathway Through mTOR Inhibition of Autophagy in Renal Tubular Epithelial Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12949363/
  11. Feb 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vericiguat attenuates cyclosporine A-induced nephropathy by targeting the NF-κB/TGF-β1 axis: an integrated network pharmacology, Mendelian randomization, and experimental study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12886507/
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    Targeting and dissociating HIF2α from the molecular chaperone Hsp70 triggers apoptosis in kidney cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12881505/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZNF395 is a Hypoxia-Responsive Regulator of Mitochondrial Glutaminolysis in Clear Cell Renal Cell Carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12875648/
  15. Jan 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Empty spiracles homeobox 2 (EMX2) transcription factor functions as a tumor suppressor in renal cell carcinoma by targeting CADM1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12807814/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Senloytics, dasatinib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12857402/
  18. Dec 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TFE3 fusion proteins promoted the progression of Xp11.2 translocation renal cell carcinoma through post-translational modification of PDL1 by upregulating CCND1/Cyclin D1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12698746/
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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666318/
  22. Nov 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigallocatechin Gallate Attenuates CaOx Crystal-Induced Renal Tubular Injury to Inhibit CaOx Nephrolithiasis via GRP94/PI3K/AKT Signaling
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    Tryptophan-Conjugated Carbon Dots with Enhanced Cellular Uptake as a Potential Drug Delivery System for Melanoma
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    pubs.acs.org/doi/10.1021/acsabm.5c01730
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    Affinity-Based Protein Profiling Revealed that HIGD1A is a Direct Target Protein of Aristolochic Acids
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513117
  26. Oct 2025
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    TCIRG1 as a Novel Prognostic Biomarker Triggering Immune Infiltration in Renal Clear Cell Carcinoma: An Integrative Study of Single-Cell and Bulk Data
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    Activation of TLR4-NF-κB signaling in renal tubular epithelial cells facilitates renal allograft fibrosis by inhibiting peroxisome biogenesis
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    sciencedirect.com/science/article/pii/S0925443925004144
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    Role of SAA1 in mediating renal fibrosis through TLR4-dependent NF-κB activation
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  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated single-cell and bulk transcriptome analysis revealed high plasticity subpopulation and promising diagnosis model for clear cell renal cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12487111/
  32. Sep 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overexpression of PON1 reduces high glucose induced renal tubular epithelial cell injury by activating PPARγ signaling pathway to alleviate diabetes nephropathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12377028/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma
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  35. Aug 2025
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    Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma
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    Design of multi-target peptide modulators for protein chaperone networks
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    The natural compound stachyose targets SGLT2-mediated metabolic reprogramming to ameliorate diabetic kidney disease
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    Novel Coumarin Derivative SZC-6 as an Allosteric Activator of SIRT3 Alleviates Diabetic Kidney Disease via the SIRT3-Foxo3a Signaling Axis
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    TRIM65 as a key regulator of ferroptosis and glycolysis in lactate-driven renal tubular injury and diabetic kidney disease
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  41. Jun 2025
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    Syndecan-1-mediated loading of VEGF-A into small extracellular vesicles facilitates peritubular capillary repair during AKI-to-CKD transition
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    PUMA reduces FASN ubiquitination to promote lipid accumulation and tumor progression in human clear cell renal cell carcinoma
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  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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    Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway
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  46. May 2025
  47. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Augmenter of liver regeneration (ALR) can regulate iron homeostasis through the INOS/NO/SLC39A14 pathway to reduce ferroptosis in acute kidney injury
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  48. Apr 2025
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    Xuebijing injection alleviates septic acute kidney injury by modulating inflammation, mitochondrial dysfunction, and endoplasmic reticulum stress
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    Glabridin ameliorates hemorrhagic shock induced acute kidney injury by activating Nrf2/HO-1 pathway
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  51. Mar 2025
  52. 52.53.155.43 52.53.155.43
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    Receptor-associated protein impairs ligand binding to megalin and megalin-dependent endocytic flux in proximal tubule cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11905868/
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    Static magnetic fields alleviate diabetic nephropathy by reducing renal cell inflammation and promoting M2 macrophage polarization
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    Both carvedilol and cimetidine alleviate cisplatin-induced nephrotoxicity via downregulating OCT2
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  56. Jan 2025
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease
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  59. Dec 2024
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    Tumor necrosis factor-stimulated gene-6 inhibits endoplasmic reticulum stress in the ischemic mouse kidney
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    Structure-guided development of selective caseinolytic protease P agonists as antistaphylococcal agents
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  62. Oct 2024
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    S100A9 promotes renal calcium oxalate stone formation via activating the TLR4-p38/MAPK-LCN2 signaling pathway
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  64. Sep 2024
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    Epigenetic alterations in bioaccumulators of cadmium: Lessons from mammalian kidneys and plants
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  66. Aug 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX11 as a prognostic biomarker linked to m6A modification and immune infiltration in renal clear cell carcinoma
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  68. elifesciences.org elifesciences.org
    Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling
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  69. Jul 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage migration inhibitory factor (MIF) suppresses mitophagy through disturbing the protein interaction of PINK1-Parkin in sepsis-associated acute kidney injury
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    Renal inflammation combined with renal function reserve reduction accelerate kidney aging via pentose phosphate pathway
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  72. May 2024
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    Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response
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  74. aacrjournals.org aacrjournals.org
    Bile acid metabolism mediates cholesterol homeostasis and promotes tumorigenesis in clear cell renal cell carcinoma
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    aacrjournals.org/cancerres/article/84/10/1570/745316/Bile-Acid-Metabolism-Mediates-Cholesterol
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    Megalin-targeted acetylcysteine polymeric prodrug ameliorates ischemia-reperfusion-induced acute kidney injury
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  77. Apr 2024
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    Genetic or pharmacologic blockade of mPGES-2 attenuates renal lipotoxicity and diabetic kidney disease by targeting Rev-Erbα/FABP5 signaling
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  79. Feb 2024
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating HMGB1 as a Potential Serum Biomarker for Early Diabetic Nephropathy Monitoring by Quantitative Proteomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830865/
  81. Dec 2023
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    ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion
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  83. www.tandfonline.com www.tandfonline.com
    GW1929 (an agonist of PPARγ) inhibits excessive production of reactive oxygen species in cisplatin-stimulated renal tubular epithelial cells, hampers cell apoptosis, and ameliorates renal injury
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    tandfonline.com/doi/abs/10.1080/01478885.2023.2286692
  84. Oct 2023
  85. www.cell.com www.cell.com
    Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling
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    cell.com/iscience/abstract/S2589-0042(23)02017-5
  86. Sep 2023
  87. www.mdpi.com www.mdpi.com
    Basement Membrane-Associated lncRNA Risk Model Predicts Prognosis and Guides Clinical Treatment in Clear Cell Renal Cell Carcinoma
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    Comprehensive Analysis of the Relationship between Xanthine Oxidoreductase Activity and Chronic Kidney Disease
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  89. Jul 2023
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetate attenuates kidney fibrosis in an oxidative stress‐dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC10354006/
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    Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells
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    sciencedirect.com/science/article/pii/S0300483X23001749
  92. Jun 2023
  93. www.nature.com www.nature.com
    piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination
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    nature.com/articles/s12276-023-01010-3
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    52.53.155.43/44daa3e55a532b68c591d2935a62e43839890393/British J Pharmacology - 2023 - He - Cpd-42 Alleviates Acute Kidney Injury via Targeting RIPK3-mediated Necroptosis-html.html
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    IL-17C neutralization protects the kidney against acute injury and chronic injury
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    sciencedirect.com/science/article/pii/S235239642300172X
  96. May 2023
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Olmesartan alleviates SARS-CoV-2 envelope protein induced renal fibrosis by regulating HMGB1 release and autophagic degradation of TGF-β1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10225711/
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    MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells
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    sciencedirect.com/science/article/pii/S2589004223007332
  99. Apr 2023
  100. www.sciencedirect.com www.sciencedirect.com
    Crabtree effect in kidney proximal tubule cells via late-stage glycolytic intermediates
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    sciencedirect.com/science/article/pii/S2589004223005394
  101. Mar 2023
  102. academic.oup.com academic.oup.com
    Klotho protects chromosomal DNA from radiation-induced damage
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    academic.oup.com/jb/advance-article/doi/10.1093/jb/mvad001/6986419
  103. Dec 2022
  104. www.sciencedirect.com www.sciencedirect.com
    Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness
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    sciencedirect.com/science/article/pii/S1535610822005657
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TWIK-related acid-sensitive K+ channel 2 promotes renal fibrosis by inducing cell cycle arrest
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    ncbi.nlm.nih.gov/pmc/articles/PMC9712759/
  106. Nov 2022
  107. www.sciencedirect.com www.sciencedirect.com
    Yishen-Qingli-Huoxue Formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling
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    sciencedirect.com/science/article/pii/S0944711322006341
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    Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair
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    sciencedirect.com/science/article/pii/S2211124722014796
  109. Aug 2022
  110. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Transfection with Plasmid-Encoding lncRNA-SLERCC nanoparticle-mediated delivery suppressed tumor progression in renal cell carcinoma
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    jeccr.biomedcentral.com/articles/10.1186/s13046-022-02467-2
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High sodium reduced the expression of PTH1R and Klotho by inhibiting 1,25(OH)2D3 synthesis in cultured proximal tubule epithelial cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9347055/
  112. Jun 2022
  113. www.imrpress.com www.imrpress.com
    PINK1/Parkin-Mediated Mitophagy Plays a Protective Role in Albumin Overload-Induced Renal Tubular Cell Injury
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    imrpress.com/journal/FBL/27/6/10.31083/j.fbl2706184
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    P53 regulates mitochondrial biogenesis via transcriptionally induction of mitochondrial ribosomal protein L12
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  115. May 2022
  116. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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