123 Matching Annotations
  1. Last 7 days
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    Lumbrokinase ameliorates chronic social defeat stress-induced behavioral impairments through modulation of miR-340-5p and SUMO2 signaling
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    sciencedirect.com/science/article/pii/S002839082600359X
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    A novel velvet antler-derived antioxidant peptide protects HT22 cells against H2O2-induced oxidative stress through regulation of the Keap1/Nrf2 pathway
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    sciencedirect.com/science/article/pii/S2212429226016986
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    Multi-Omics Analysis Reveals That Aβ42- Me3 Co-Aggregation Induces Mitophagy Blockade in Early Stages of Alzheimer's Disease
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    onlinelibrary.wiley.com/doi/10.1002/mco2.70984
  5. Sep 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lactobacillus acidophilus CICC 22162 alleviates sleep deprivation-induced cognitive impairment by remodeling gut microbiota and enhancing S-adenosylmethionine-mediated neuroimmune regulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13536946/
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    Microglial TLR7 contributes to traumatic brain injury-induced neuroinflammation in mice
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    nature.com/articles/s41401-026-01915-5
  8. Aug 2026
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70642
  10. Jul 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase
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    pmc.ncbi.nlm.nih.gov/articles/PMC13410807/
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    Aspirin alleviates long-term high-fat diet-induced depressive-like behavior in male mice via suppressing arachidonic acid-mediated microglial activation and neuroinflammation
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    nature.com/articles/s41380-026-03752-8
  13. pubs.acs.org pubs.acs.org
    Activation of ACE2 by Hazelnut-Derived Peptide YYLLVR: A Novel Strategy against Hypertension-Induced Cognitive Impairment
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    pubs.acs.org/doi/10.1021/acs.jafc.6c06355
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small proline-rich repeat protein 1A-mediated ephrin-A5 downregulation drives neuropathic pain via brain-derived neurotrophic factor/Tropomyosin receptor kinase B signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13380215/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sevoflurane ameliorates cerebral ischemia–reperfusion injury by modulating mitochondrial dynamics and attenuating apoptosis via Shh-YAP1 signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13371202/
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    Hippocampal Hbα deficiency induces neuronal apoptosis by promoting the accumulation of AGEs
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    sciencedirect.com/science/article/pii/S0014299926006217
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    Terpenoids From Leaves of Diospyros kaki and Their Neuroprotective Effects
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71443
  18. Jun 2026
  19. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Multi-Component Functionalized Bifidobacterium Longum Hydrogel for Multi-Target Integrated Therapy of Colitis-Associated Anxiety and Depression
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76242
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    Biomimetic Hydrogel System Targeting S100A8 Centered Neuroimmune Crosstalk and Hypoxia Induced Neuronal Injury
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76220
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    Postnatal deletion of ZIP9 leads to premature mortality and hippocampal-dependent cognitive decline with disrupted brain–gut–lipid homeostasis
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    sciencedirect.com/science/article/pii/S3117817026000068
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    Discovery and Optimization of Novel Carbazole-Based Ferroptosis Inhibitors
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71430
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    Natural polyphenol-based nanofibers facilitate macrophage-mediated erythrophagocytosis for intracerebral hemorrhage therapy
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    sciencedirect.com/science/article/pii/S1748013226001374
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    Sleeve gastrectomy improves cognition by enhancing central ERK/CREB/BDNF pathway through increased GIP secretion
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    sciencedirect.com/science/article/pii/S2589004226016676
  25. May 2026
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRPV4 is involved in NLRP3 and NLRP1 inflammasomes activation after pilocarpine-induced status epilepticus in mice: Concise title: TRPV4-mediated inflammasome activation in epilepsy
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  27. Apr 2026
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    Fluoxetine Alleviates Vascular Cognitive Impairment by Activating the Nrf2/ARE Pathway via Sp1-Mediated OTUD1 Transcription
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    tandfonline.com/doi/abs/10.1080/10715762.2026.2658796
  29. pubs.acs.org pubs.acs.org
    An Interpretable, Thermodynamics-Based Deep Learning Framework for Predicting and Optimizing Drug Membrane Permeability
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.6c00204
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    SARS-CoV-2 directly infects the inner ear and causes hearing dysfunction
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    sciencedirect.com/science/article/pii/S2211124726003293
  31. Mar 2026
  32. pubs.acs.org pubs.acs.org
    Destabilized Soluble SOD1 Species as Potential Determinants of Disease Severity in Familial Amyotrophic Lateral Sclerosis
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    pubs.acs.org/doi/full/10.1021/acschemneuro.5c00668
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    Nrf2 maintains reactive oxygen species at an optimal level during endoplasmic reticulum stress in HT22 cells
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    Multi-component functionalized Bifidobacterium longum hydrogel for multi-target integrated therapy of colitis-associated anxiety and depression
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    biorxiv.org/content/10.64898/2026.03.10.710940v1
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    Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70402
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    FAT4 loss promotes tumor growth and ferroptosis resistance in hepatocellular carcinoma via PI3K/AKT pathway activation
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    link.springer.com/article/10.1007/s12094-026-04302-y
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    The landscape of gene mutations in a cohort of 3353 Han Chinese children with nonsyndromic hearing loss
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    sciencedirect.com/science/article/pii/S2352396426000939
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    Nature-Inspired Surface Modification Strategy Reverses the Autophagic Flux Impairment of Mitochondrial Transplantation for Attenuating Ischemic Strokes
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518969
  39. Feb 2026
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anesthetic gas sevoflurane postconditioning alleviates cognitive impairment induced by hemorrhagic shock and resuscitation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12935133/
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    Targeting AARS1-dependent lactylation improves neuronal process plasticity and mitigates cognitive deficits in sepsis-associated encephalopathy
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    sciencedirect.com/science/article/pii/S0889159126002412
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inflammatory Factors Derived From Metabolic Dysfunction‐Alcoholic Fatty Liver Disease: Inducers of Anxiety and Spatial Memory Impairment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12887228/
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    Lumbrokinase modulates tissue plasminogen activator and alleviates behavioral and cognitive deficits in mice with chronic social defeat stress
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    sciencedirect.com/science/article/pii/S0753332226000569
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    Neuron-glioma synaptic transmission amplified by free 19S proteasome-mediated AMPAR deubiquitination promotes tumor progression
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    sciencedirect.com/science/article/pii/S1878747926000176
  45. Jan 2026
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    Co-treatment Strategy Supports Neuroprotection by Intersecting p62-Keap1-NRF2 and Autophagy Signaling Pathways in the Cellular Model of Parkinson's Disease
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    link.springer.com/article/10.1007/s10571-025-01610-9
  47. Dec 2025
  48. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress-Induced Depression in Male Mice
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202513438
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    Modest improvement of metabolic and behavioral deficits with long-term ambroxol treatment in a Pink1−/−SNCAA53T double mutant mouse model of Parkinson’s disease
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    nature.com/articles/s41401-025-01690-9
  50. Nov 2025
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    BDNF exerts an NRF2-dependent cytoprotective function via a receptor-independent pathway
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    sciencedirect.com/science/article/pii/S2211124725013592
  52. Oct 2025
  53. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Optimized Single-Shank Silicon Neural Probe for Neural Recording in Non-Human Primates
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    advanced.onlinelibrary.wiley.com/doi/10.1002/admt.202501356
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    Unveiling the Therapeutic Potential of D2AAK1 and Its Derivatives: Mechanistic Insights and Applications in Neurodegenerative Disease Treatment
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70232
  55. Sep 2025
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    ANXA2 knockdown inhibits oxidative stress and pyroptosis to alleviate epilepsy by suppressing the toll-like receptor (TLR) pathway
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    sciencedirect.com/science/article/pii/S0898656825005558
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    Elevated hexosylceramides in Parkinson’s disease cause gene upregulations in neurons mimicking responses to pathogens
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    nature.com/articles/s41531-025-01114-9
  58. Aug 2025
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    Neurophilic Biomimetic Lipoprotein-Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202509405
  60. Jul 2025
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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  62. Jun 2025
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    Inhibition of phosphodiesterase-4 by rolipram alleviates anxiety-like behavior in mice with PTSD by modulating neuroinflammation and synaptic plasticity via cAMP signaling
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  65. May 2025
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    Bromodomain-containing protein 4 knockdown promotes... : Neural Regeneration Research
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    Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice
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    Therapeutic time window of Sodium of Danshensu on cerebral ischemia and its mechanism of inhibiting oxidative stress and ferroptosis through Nrf2 pathway
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    sciencedirect.com/science/article/pii/S0361923025002084
  69. Apr 2025
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    Molecular Mechanisms of Propofol-Induced Cognitive Impairment: Suppression of Critical Hippocampal Pathways
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    Hydroxysafflor yellow A inhibits neuronal ferroptosis and ferritinophagy in ischemic stroke
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    sciencedirect.com/science/article/pii/S0925443925002157
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    Retinal degeneration protein 3 mutants are associated with cell-cycle arrest and apoptosis
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  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human neural stem cell-derived exosomes activate PINK1/Parkin pathway to protect against oxidative stress-induced neuronal injury in ischemic stroke
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    pmc.ncbi.nlm.nih.gov/articles/PMC11971779/
  74. Mar 2025
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    C30 reversed-phase HPLC analysis and in vitro bioactivity evaluation of decursin and decursinol angelate in Angelicae Gigantis Radix
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  76. Dec 2024
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    Antiferroptotic properties of allicin and related organosulfur compounds—diallyl disulfide and diallyl trisulfide—from Garlic
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    sciencedirect.com/science/article/pii/S0278691524006902
  78. Nov 2024
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    Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis
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  80. Oct 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke
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    ncbi.nlm.nih.gov/pmc/articles/PMC11433893/
  82. Sep 2024
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    Bis-chalcones obtained via one-pot synthesis as the anti-neurodegenerative agents and their effect on the HT-22 cell line
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  84. Aug 2024
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    2,3-Diphosphoglyceric Acid Alleviating Hypoxic-Ischemic Brain Damage through p38 MAPK Modulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11354455/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
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    Mdivi-1 alleviates ferroptosis induced by hypoxia combined with propofol in HT22 cells by inhibiting excessive mitophagy
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    link.springer.com/article/10.1007/s11033-024-09812-y
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    Exosomes derived from microglia overexpressing miR-124-3p alleviate neuronal endoplasmic reticulum stress damage after repetitive mild traumatic brain injury
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    journals.lww.com/nrronline/fulltext/2024/09000/exosomes_derived_from_microglia_overexpressing.33.aspx
  89. Jul 2024
  90. www.tandfonline.com www.tandfonline.com
    Study of the multitarget mechanism of Astragalus (HUANGQI) in the treatment of Alzheimer’s disease based on network pharmacology and molecular docking technology
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    tandfonline.com/doi/abs/10.1080/13880209.2024.2382962
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    Ferroptosis induces nucleolar stress as revealed by live-cell imaging using thioflavin T
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    sciencedirect.com/science/article/pii/S2590257124000233
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the postsynaptic scaffolding protein PSD-95 enhances BDNF signaling to mitigate depression-like behaviors in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11223518/
  93. May 2024
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Accumulation of extracellular elastin-derived peptides disturbed neuronal morphology and neuron–microglia crosstalk in aged brain
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16039
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    The actin-binding protein CAP1 represses MRTF-SRF–dependent gene expression in mouse cerebral cortex
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    science.org/doi/10.1126/scisignal.adj0032
  96. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    AdipoRon promotes amyloid-β clearance through enhancing autophagy via nuclear GAPDH-induced sirtuin 1 activation in Alzheimer's disease
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16400
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    Targeting the postsynaptic scaffolding protein PSD-95 enhances BDNF signaling to mitigate depression-like behaviors in mice
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    science.org/doi/10.1126/scisignal.adn4556
  98. Apr 2024
  99. www.sciencedirect.com www.sciencedirect.com
    Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity
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    sciencedirect.com/science/article/pii/S1550413124000895
  100. Feb 2024
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883488/
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17099
  103. www.mdpi.com www.mdpi.com
    Neuroprotection via Carbon Monoxide Depends on the Circadian Regulation of CD36-Mediated Microglial Erythrophagocytosis in Hemorrhagic Stroke
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    mdpi.com/1422-0067/25/3/1680
  104. Jan 2024
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic Characterization of Rat Hepatic Stellate Cell Line PAV-1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10297474/
  106. Nov 2023
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural features localizing the ferroptosis inhibitor GIF-2197-r to lysosomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10620646/
  108. Oct 2023
  109. www.mdpi.com www.mdpi.com
    Neuroprotective Effects of Water Extract from Brown Algae Petalonia binghamiae in an Experimental Model of Focal Cerebral Ischemia In Vitro and In Vivo
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    mdpi.com/1467-3045/45/10/531
  110. Sep 2023
  111. link.springer.com link.springer.com
    Deubiquitylating Enzyme OTUB1 Facilitates Neuronal Survival After Intracerebral Hemorrhage Via Inhibiting NF-κB-triggered Apoptotic Cascades
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    link.springer.com/article/10.1007/s12035-023-03676-2
  112. journals.physiology.org journals.physiology.org
    Mechanism of SOX10 in ferroptosis of hippocampal neurons after intracerebral hemorrhage via the miR-29a-3p/ACSL4 axis
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    journals.physiology.org/doi/10.1152/jn.00374.2022
  113. Aug 2023
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    Ring finger protein 146-mediated long-chain fatty-acid-coenzyme A ligase 4 ubiquitination regulates ferroptosis-induced neuronal damage in ischemic stroke
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  115. Jul 2023
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  130. Oct 2022
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  148. Aug 2021
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  155. May 2021
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  157. Apr 2021
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  159. Mar 2021
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  161. Feb 2021
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  163. Dec 2020
  164. elifesciences.org elifesciences.org
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  166. Sep 2020
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  176. Nov 2017
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