143 Matching Annotations
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    The upregulation of GDF15 is controlled epigenetically by oncogenic TCF19 signaling in human hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S258900422501764X
  3. Oct 2025
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    CBX4 acetoacetylation as an inhibitory mechanism of HIF-1α activity
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    Catenibacterium mitsuokai promotes hepatocellular carcinogenesis by binding to hepatocytes and generating quinolinic acid
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    sciencedirect.com/science/article/pii/S1550413125003869
  6. Sep 2025
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    miR-199a-5p/GPR89A axis modulates sorafenib resistance in hepatocellular carcinoma through glutamate metabolic reprogramming
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    HBV-encoded circRNA-5 promotes hepatocellular carcinoma progression by regulating the miR-9-3p/Hippo signaling axis
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  9. Aug 2025
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    HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma
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    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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    Computational framework for prioritizing candidate compounds overcoming the resistance of pancancer immunotherapy
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    Targeting MCM10 disrupts cancer stemness and counteracts sorafenib resistance in hepatocellular carcinoma
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    ASH2L-K312-Lac Stimulates Angiogenesis in Tumors to Expedite the Malignant Progression of Hepatocellular Carcinoma
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  15. Jul 2025
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    Thyroid hormone suppresses cell growth by regulating CDK2 and cyclin E1 expression via Hepsin
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    IFNγ augments TKI efficacy by alleviating protein unfolding stress to promote GSDME-mediated pyroptosis in hepatocellular carcinoma
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    Frontiers | TREM1 is essential for maintaining stemness of liver cancer stem-like cells in hepatocellular carcinoma
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  19. Jun 2025
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    BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival
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  22. May 2025
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    ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression
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  24. Apr 2025
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    Downregulation of PD-L1 expression by Wnt pathway inhibition to enhance PD-1 blockade efficacy in hepatocellular carcinoma
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  30. Feb 2025
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    AKR1D1 suppresses liver cancer progression by promoting bile acid metabolism-mediated NK cell cytotoxicity
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    RHEB neddylation by the UBE2F-SAG axis enhances mTORC1 activity and aggravates liver tumorigenesis
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    Lactate drives senescence-resistant lineages in hepatocellular carcinoma via histone H2B lactylation of NDRG1
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    Machine learning-based integration reveals immunological heterogeneity and the clinical potential of T cell receptor (TCR) gene pattern in hepatocellular carcinoma
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    Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3
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  38. Jan 2025
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    Re-evaluation of the relationship between PrPc expression and patient prognosis in primary esophageal squamous cell carcinoma and primary hepatocellular carcinoma
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  42. Dec 2024
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    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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    Carbonic anhydrase 2 facilitates sorafenib resistance by counteracting MCT4-mediated intracellular pH dysregulation in HCC
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  46. Nov 2024
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    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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  50. Oct 2024
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    Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library
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  52. Aug 2024
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    YTHDF3-mediated m6A modification of NKD1 regulates hepatocellular carcinoma invasion and metastasis by activating the WNT/β-catenin signaling axis
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    Therapeutic application of extracellular vesicular EGFR isoform D as a co-drug to target squamous cell cancers with tyrosine kinase inhibitors
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  59. Jul 2024
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    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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    Cyclin dependent kinase 9 inhibition reduced programmed death-ligand 1 expression and improved treatment efficacy in hepatocellular carcinoma
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  63. Jun 2024
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    Hypoxia-responsive lncRNA MIR155HG promotes PD-L1 expression in hepatocellular carcinoma cells by enhancing HIF-1α mRNA stability
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  65. May 2024
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    DNA of neutrophil extracellular traps binds TMCO6 to impair CD8+ T-cell immunity in hepatocellular carcinoma.
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  67. Apr 2024
  68. www.embopress.org www.embopress.org
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    STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma
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  70. Mar 2024
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    Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance
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  72. www.biorxiv.org www.biorxiv.org
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  75. Feb 2024
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    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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    Inhibition of RhoGEF/RhoA alleviates regorafenib resistance and cancer stemness via Hippo signaling pathway in hepatocellular carcinoma
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  79. Jan 2024
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    Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection
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  81. Dec 2023
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    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    Direct tumor irradiation potentiates adoptive NK cell targeting against parental and stem-like cancer in human liver cancer models.
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    Sex difference in liver diseases: How preclinical models help to dissect the sex-related mechanisms sustaining NAFLD and hepatocellular carcinoma
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  86. Nov 2023
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    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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    Loss of Krüppel-like factor-10 facilitates the development of chemical-induced liver cancer in mice
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    Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway
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  90. Oct 2023
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    Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives
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  92. Sep 2023
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    Synergism of the receptor tyrosine kinase Axl with ErbB receptors mediates resistance to regorafenib in hepatocellular carcinoma
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    In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma
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  95. Aug 2023
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    CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway
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  97. Jul 2023
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    PPM1H is down-regulated by ATF6 and dephosphorylates p-RPS6KB1 to inhibit progression of hepatocellular carcinoma
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  100. Jun 2023
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition
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  104. May 2023
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    Targeting of Annexin A1 in Tumor-associated Macrophages as a Therapeutic Strategy for Hepatocellular Carcinoma
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    Comprehensive Metabolic Tracing Reveals the Origin and Catabolism of Cysteine in Mammalian Tissues and Tumors
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  108. Apr 2023
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    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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  111. Mar 2023
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    Transcriptional Regulation of Liver-Type OATP1B3 (Lt-OATP1B3) and Cancer-Type OATP1B3 (Ct-OATP1B3) Studied in Hepatocyte-Derived and Colon Cancer-Derived Cell Lines
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  113. Feb 2023
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    A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes
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  115. Jan 2023
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    Functional HIV-1/HCV cross-reactive antibodies isolated from a chronically co-infected donor
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