140 Matching Annotations
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    Gasdermin D Cleavage and Cytokine Release, Indicative of Pyroptotic Cell Death, Induced by Ophiobolin A in Breast Cancer Cell Lines
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    mdpi.com/1422-0067/27/2/618
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    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    pubs.acs.org/doi/10.1021/acs.jmedchem.5c02082
  4. Dec 2025
  5. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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  6. Oct 2025
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    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523003/
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    The deubiquitinase USP9X and E3 ligase WWP1 orchestrate IGF2BP2 ubiquitination homeostasis to drive TNBC progression and cisplatin sensitivity
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    Phosphorylation of Plectin by Akt3 Promotes Triple-Negative Breast Cancer Cell Invasive Migration
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    PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
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    sciencedirect.com/science/article/pii/S2211124725011623
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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  13. Sep 2025
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    HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer
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    Chemotherapy modulation by a cancer-associated microbiota metabolite
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    HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
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    PCDHGB7 inhibits the progression of triple‐negative breast cancer by suppressing XRCC5/MYC‐mediated ribosome biogenesis
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  20. Aug 2025
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    Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
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    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma
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  24. Jul 2025
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    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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  26. May 2025
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    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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  28. Apr 2025
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    Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer
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    Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer
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    CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
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    Sulfatase 2 inhibition sensitizes triple-negative breast cancer cells to paclitaxel through augmentation of extracellular ATP
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  33. Mar 2025
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    KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
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  36. Feb 2025
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    Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to promote breast cancer metastasis
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    Novel Pannexin 1 isoform is increased in cancer
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  41. Jan 2025
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    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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  45. Dec 2024
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    TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer
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    Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation
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  48. Nov 2024
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    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer
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  51. Sep 2024
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    Global and single-cell proteomics view of the co-evolution between neural progenitors and breast cancer cells in a co-culture model
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    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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  55. Aug 2024
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    A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors
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    Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis
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    Enhanced expression of galectin-9 in triple negative breast cancer cells following radiotherapy: Implications for targeted therapy
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    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
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  61. Jul 2024
  62. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
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  65. May 2024
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    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
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    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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  69. Apr 2024
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    Droplet-based proteomics reveals CD36 as a marker for progenitors in mammary basal epithelium
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  71. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer
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  74. Feb 2024
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    Identification of an H-Ras nanocluster disrupting peptide
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    Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP
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  78. Jan 2024
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    Exploring the Multifaceted Impact of Lanthanides on Physiological Pathways in Human Breast Cancer Cells
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  80. Dec 2023
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    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer
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  84. Nov 2023
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    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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  86. Oct 2023
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    Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
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    ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
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    NR1D1 Stimulates Antitumor Immune Responses in Breast Cancer by Activating cGAS-STING Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10538367/
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    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
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    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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  92. Aug 2023
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    LncRNA TYMSOS facilitates breast cancer metastasis and immune escape through downregulating ULBP3
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  94. May 2023
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    The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer
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    onlinelibrary.wiley.com/doi/10.1002/advs.202201701
  96. Apr 2023
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    Gallium maltolate shows synergism with cisplatin and activates nucleolar stress and ferroptosis in human breast carcinoma cells
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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer
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  100. Feb 2023
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lipid raft protein flotillin-1 is important for the interaction between SOS1 and H-Ras/K-Ras, leading to Ras activation
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    onlinelibrary.wiley.com/doi/epdf/10.1002/ijc.34443
  102. Jan 2023
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine
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    ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
  104. Oct 2022
  105. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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  106. Sep 2022
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    A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
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  108. Jun 2022
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    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
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    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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  111. May 2022
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells
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    CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome
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    Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer
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