160 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13403735/
  3. Jul 2026
  4. aacrjournals.org aacrjournals.org
    CircADAMTS12 Inhibits the Anti-Tumor Activity of Microglia to Enable Metastatic Colonization in the Brain
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    aacrjournals.org/cancerres/article/85/24/4977/770549/circADAMTS12-Inhibits-the-Antitumor-Activity-of
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    Distinct metabolic dependency on BCAA defines cancer stemness and malignancy in human triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124726007084
  6. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple-Negative Breast Cancer
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202520252
  7. Jun 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin-like growth factor 1 receptor regulates breast cancer cell adhesion through beta-1 integrin
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    pmc.ncbi.nlm.nih.gov/articles/PMC13229645/
  9. May 2026
  10. www.biorxiv.org www.biorxiv.org
    Unveiling Gloriosine as a Dual-Acting Regulator of Glutamine Metabolism and Ferroptosis in Triple-Negative Breast Cancer: Insights from Network Pharmacology and Experimental Validation
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    biorxiv.org/content/10.64898/2026.05.17.725321v1
  11. 54.241.53.176 54.241.53.176
    2026.05.13.724989.1.full-html.html
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    54.241.53.176/029742425e35b5db4d975de9e7a29b7b0a9c078f/2026.05.13.724989.1.full-html.html
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and Evaluation of Biomarkers for Triple-Negative Breast Cancer Subtypes Uncovers Patient Stratification and Targeted Therapeutic Strategies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13176827/
  13. www.sciencedirect.com www.sciencedirect.com
    Integrative in silico analysis predicts a potential interaction between lncRNA LINC01133 and miR-181A2HG in the Hs578T Triple-Negative Breast Cancer Cell Line
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    sciencedirect.com/science/article/pii/S3050787126002039
  14. aacrjournals.org aacrjournals.org
    ZSTK3744, a novel aryl hydrocarbon receptor agonist, exhibits efficacy against chemotherapy-resistant triple-negative breast cancer
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    aacrjournals.org/cancerrescommun/article/6/2/421/774901/ZSTK3744-a-Novel-Aryl-Hydrocarbon-Receptor-Agonist
  15. Apr 2026
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NFYC upregulates KLF1 expression and activate LDHA to drive glycolysis and tumor growth in glioblastoma cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13102801/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CircNSD2 promotes metastasis and immune escape by increasing the USP10/SRSF6-mediated alternative splicing of TPM1 in TNBC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13088798/
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrative Genomic Analysis Identifies MAGT1 as a Key Regulator of Proliferation and Poor Prognosis in Breast Cancer
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    onlinelibrary.wiley.com/doi/10.1155/humu/8673018
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LINC01235 Is an Upstream Regulator of the NFIB Gene and the Notch Pathway in Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221212/
  20. Mar 2026
  21. www.sciencedirect.com www.sciencedirect.com
    Targeting the noncanonical function of metabolic enzyme PHGDH in driving PD-L1 expression and cancer immune evasion
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    sciencedirect.com/science/article/pii/S2666379126001217
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    Comprehensive single-cell metabolic profiling identifies targets to sensitize triple-negative breast cancer to chemo-immunotherapy
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    sciencedirect.com/science/article/pii/S2666379126000765
  23. www.nature.com www.nature.com
    Arginine methylation-dependent stabilization of SUV39H1 promotes breast cancer growth
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    nature.com/articles/s41388-026-03712-0
  24. Feb 2026
  25. www.sciencedirect.com www.sciencedirect.com
    RAD51 succinylation regulates homologous recombination and contributes to the chemosensitivity in cancer
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    sciencedirect.com/science/article/pii/S1097276526000626
  26. Jan 2026
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13019158/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fast enrichment and detection of circulating tumor cells from large volumes of whole blood of breast cancer patients utilizing a functionalized bioaffinity CTC filtration membrane
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    pmc.ncbi.nlm.nih.gov/articles/PMC12811197/
  29. www.mdpi.com www.mdpi.com
    Gasdermin D Cleavage and Cytokine Release, Indicative of Pyroptotic Cell Death, Induced by Ophiobolin A in Breast Cancer Cell Lines
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    mdpi.com/1422-0067/27/2/618
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12833852/
  31. Dec 2025
  32. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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  33. Oct 2025
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    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012318
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523003/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The deubiquitinase USP9X and E3 ligase WWP1 orchestrate IGF2BP2 ubiquitination homeostasis to drive TNBC progression and cisplatin sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500958/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Plectin by Akt3 Promotes Triple-Negative Breast Cancer Cell Invasive Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12508894/
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    PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
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    sciencedirect.com/science/article/pii/S2211124725011623
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  40. Sep 2025
  41. www.sciencedirect.com www.sciencedirect.com
    HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413125003821
  42. 52.53.155.43 52.53.155.43
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    Chemotherapy modulation by a cancer-associated microbiota metabolite
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    sciencedirect.com/science/article/pii/S2405471225002303
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    HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
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    sciencedirect.com/science/article/pii/S0092867425009298
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCDHGB7 inhibits the progression of triple‐negative breast cancer by suppressing XRCC5/MYC‐mediated ribosome biogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405659/
  47. Aug 2025
  48. www.nature.com www.nature.com
    Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
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    nature.com/articles/s41467-025-62486-3
  49. www.cell.com www.cell.com
    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    cell.com/cell/abstract/S0092-8674(25)00856-6
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12333905/
  51. Jul 2025
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  53. May 2025
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35471
  55. Apr 2025
  56. www.sciencedirect.com www.sciencedirect.com
    Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004224013622
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999952/
  58. www.sciencedirect.com www.sciencedirect.com
    CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
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    sciencedirect.com/science/article/pii/S2451945625000960
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sulfatase 2 inhibition sensitizes triple-negative breast cancer cells to paclitaxel through augmentation of extracellular ATP
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    pmc.ncbi.nlm.nih.gov/articles/PMC11951697/
  60. Mar 2025
  61. www.sciencedirect.com www.sciencedirect.com
    KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
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    sciencedirect.com/science/article/pii/S1534580725001510
  62. 52.53.155.43 52.53.155.43
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  63. Feb 2025
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to identify small-molecule inhibitors against cancer drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11821401/
  66. aacrjournals.org aacrjournals.org
    Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to promote breast cancer metastasis
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    aacrjournals.org/cancerres/article/84/18/3023/747792/Arginine-Methylation-of-DDX3-by-PRMT1-Mediates
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    Novel Pannexin 1 isoform is increased in cancer
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    52.53.155.43/248e2b0e257da849dadde63c071f77bcede2b26b/2024.09.09.612143v3.full-html.html
  68. Jan 2025
  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35271
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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    sciencedirect.com/science/article/pii/S1535610824004434
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  72. Dec 2024
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609630/
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    Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation
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    sciencedirect.com/science/article/pii/S2211124724013433
  75. Nov 2024
  76. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    biorxiv.org/content/10.1101/2024.11.07.622456v1
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539583/
  78. Sep 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global and single-cell proteomics view of the co-evolution between neural progenitors and breast cancer cells in a co-culture model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11404160/
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
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    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945624003234
  82. Aug 2024
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11325149/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320833/
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    Enhanced expression of galectin-9 in triple negative breast cancer cells following radiotherapy: Implications for targeted therapy
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35107
  87. www.cell.com www.cell.com
    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
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    cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
  88. Jul 2024
  89. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
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    biorxiv.org/content/10.1101/2024.07.22.604482v1
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
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  92. May 2024
  93. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13667
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  96. Apr 2024
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Droplet-based proteomics reveals CD36 as a marker for progenitors in mammary basal epithelium
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045875/
  98. Mar 2024
  99. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
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    Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10902018/
  101. Feb 2024
  102. 52.53.155.43 52.53.155.43
    Identification of an H-Ras nanocluster disrupting peptide
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    52.53.155.43/50febc729cb1f3f2f29f241e3592121bf7d8fba9/2023.09.07.556635v1.full-html.html
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    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
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    52.53.155.43/d64025fcba7405c73976a9e0dc65e9989e0d835f/2023.08.23.554263v1.full-html.html
  104. www.biorxiv.org www.biorxiv.org
    Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP
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    biorxiv.org/content/10.1101/2023.09.15.557965v1
  105. Jan 2024
  106. www.sciencedirect.com www.sciencedirect.com
    Exploring the Multifaceted Impact of Lanthanides on Physiological Pathways in Human Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S0300483X2400012X
  107. Dec 2023
  108. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
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