136 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523003/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The deubiquitinase USP9X and E3 ligase WWP1 orchestrate IGF2BP2 ubiquitination homeostasis to drive TNBC progression and cisplatin sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500958/
  4. Oct 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phosphorylation of Plectin by Akt3 Promotes Triple-Negative Breast Cancer Cell Invasive Migration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12508894/
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    PHF19 drives the formation of PRC2 clusters to enhance motility in TNBC cells
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    sciencedirect.com/science/article/pii/S2211124725011623
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  8. Sep 2025
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    HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S1550413125003821
  10. 52.53.155.43 52.53.155.43
    2025.09.04.674332v2.full-html.html
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    1-s2.0-S2589004225018139-main-html.html
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    Chemotherapy modulation by a cancer-associated microbiota metabolite
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    sciencedirect.com/science/article/pii/S2405471225002303
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    HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
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    sciencedirect.com/science/article/pii/S0092867425009298
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCDHGB7 inhibits the progression of triple‐negative breast cancer by suppressing XRCC5/MYC‐mediated ribosome biogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405659/
  15. Aug 2025
  16. www.nature.com www.nature.com
    Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis
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    nature.com/articles/s41467-025-62486-3
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12406974/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12333905/
  19. Jul 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  21. May 2025
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of autotaxin activity with IOA-289 decreases fibrosis in mouse E0771 breast tumors
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35471
  23. Apr 2025
  24. www.sciencedirect.com www.sciencedirect.com
    Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004224013622
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999952/
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    CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
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    sciencedirect.com/science/article/pii/S2451945625000960
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sulfatase 2 inhibition sensitizes triple-negative breast cancer cells to paclitaxel through augmentation of extracellular ATP
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    pmc.ncbi.nlm.nih.gov/articles/PMC11951697/
  28. Mar 2025
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    KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
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  30. 52.53.155.43 52.53.155.43
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  31. Feb 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to identify small-molecule inhibitors against cancer drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11821401/
  34. aacrjournals.org aacrjournals.org
    Arginine methylation of DDX3 by PRMT1 mediates mitochondrial homeostasis to promote breast cancer metastasis
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    aacrjournals.org/cancerres/article/84/18/3023/747792/Arginine-Methylation-of-DDX3-by-PRMT1-Mediates
  35. 52.53.155.43 52.53.155.43
    Novel Pannexin 1 isoform is increased in cancer
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    52.53.155.43/248e2b0e257da849dadde63c071f77bcede2b26b/2024.09.09.612143v3.full-html.html
  36. Jan 2025
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35271
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    Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1
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  40. Dec 2024
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast Cancer
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    Cytoskeletal activation of NHE1 regulates mechanosensitive cell volume adaptation and proliferation
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    sciencedirect.com/science/article/pii/S2211124724013433
  43. Nov 2024
  44. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    biorxiv.org/content/10.1101/2024.11.07.622456v1
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of heparan sulfate in enhancing the chemotherapeutic response in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539583/
  46. Sep 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global and single-cell proteomics view of the co-evolution between neural progenitors and breast cancer cells in a co-culture model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11404160/
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
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    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945624003234
  50. Aug 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11325149/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320833/
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced expression of galectin-9 in triple negative breast cancer cells following radiotherapy: Implications for targeted therapy
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35107
  55. www.cell.com www.cell.com
    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
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    cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
  56. Jul 2024
  57. www.biorxiv.org www.biorxiv.org
    The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
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    biorxiv.org/content/10.1101/2024.07.22.604482v1
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  59. 52.53.155.43 52.53.155.43
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  60. May 2024
  61. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13667
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11097164/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  64. Apr 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Droplet-based proteomics reveals CD36 as a marker for progenitors in mammary basal epithelium
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045875/
  66. Mar 2024
  67. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of hydroxymethylglutharyl-coenzyme A reductase in the induction of stem-like states in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10902018/
  69. Feb 2024
  70. 52.53.155.43 52.53.155.43
    Identification of an H-Ras nanocluster disrupting peptide
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    52.53.155.43/50febc729cb1f3f2f29f241e3592121bf7d8fba9/2023.09.07.556635v1.full-html.html
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    An improved PDE6D inhibitor combines with Sildenafil to synergistically inhibit KRAS mutant cancer cell growth
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    52.53.155.43/d64025fcba7405c73976a9e0dc65e9989e0d835f/2023.08.23.554263v1.full-html.html
  72. www.biorxiv.org www.biorxiv.org
    Sulfatase 2 Inhibition Sensitizes Triple-Negative Breast Cancer Cells to Chemotherapy Through Augmentation of Extracellular ATP
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    biorxiv.org/content/10.1101/2023.09.15.557965v1
  73. Jan 2024
  74. www.sciencedirect.com www.sciencedirect.com
    Exploring the Multifaceted Impact of Lanthanides on Physiological Pathways in Human Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S0300483X2400012X
  75. Dec 2023
  76. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  77. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10683240/
  79. Nov 2023
  80. www.sciencedirect.com www.sciencedirect.com
    Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004223023854
  81. Oct 2023
  82. www.sciencedirect.com www.sciencedirect.com
    Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
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    sciencedirect.com/science/article/pii/S2211124723012688
  83. www.mdpi.com www.mdpi.com
    ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
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    mdpi.com/1422-0067/24/19/14566
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NR1D1 Stimulates Antitumor Immune Responses in Breast Cancer by Activating cGAS-STING Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10538367/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543979/
  86. dx.doi.org dx.doi.org
    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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    dx.doi.org/10.1158/2767-9764.CRC-23-0236
  87. Aug 2023
  88. www.sciencedirect.com www.sciencedirect.com
    LncRNA TYMSOS facilitates breast cancer metastasis and immune escape through downregulating ULBP3
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    sciencedirect.com/science/article/pii/S2589004223016334
  89. May 2023
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer
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    onlinelibrary.wiley.com/doi/10.1002/advs.202201701
  91. Apr 2023
  92. link.springer.com link.springer.com
    Gallium maltolate shows synergism with cisplatin and activates nucleolar stress and ferroptosis in human breast carcinoma cells
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    link.springer.com/article/10.1007/s13402-023-00804-x
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10092761/
  94. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13412
  95. Feb 2023
  96. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lipid raft protein flotillin-1 is important for the interaction between SOS1 and H-Ras/K-Ras, leading to Ras activation
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    onlinelibrary.wiley.com/doi/epdf/10.1002/ijc.34443
  97. Jan 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4+ Th1 Responses and Potential Use as a Cancer Vaccine
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    ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
  99. Oct 2022
  100. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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    sciencedirect.com/science/article/pii/S1550413122004119
  101. Sep 2022
  102. www.sciencedirect.com www.sciencedirect.com
    A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
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    sciencedirect.com/science/article/pii/S2211124722011901
  103. Jun 2022
  104. www.sciencedirect.com www.sciencedirect.com
    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
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    sciencedirect.com/science/article/pii/S258900422200863X
  105. www.sciencedirect.com www.sciencedirect.com
    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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    sciencedirect.com/science/article/pii/S2211124722006453
  106. May 2022
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9127384/
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome
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    ncbi.nlm.nih.gov/pmc/articles/PMC9125938/
  109. www.sciencedirect.com www.sciencedirect.com
    Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004222006113
  110. www.nature.com www.nature.com
    A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues
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    nature.com/articles/s41596-022-00694-7
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Augmentation of Extracellular ATP Synergizes With Chemotherapy in Triple Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9065442/
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Density-Dependent Migration Characteristics of Cancer Cells Driven by Pseudopod Interaction
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    ncbi.nlm.nih.gov/pmc/articles/PMC9084912/
  113. Apr 2022
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B
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    ncbi.nlm.nih.gov/pmc/articles/PMC8954975/
  115. Mar 2022
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  174. Nov 2018
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  181. Nov 2017
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