142 Matching Annotations
  1. Last 7 days
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    Hedgehog signaling is hampered by inhibition of cholesterol biosynthesis: The GLI1-DNMT1 cooperativity is a critical factor in controlling stemness and EMT in glioblastoma cells
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    sciencedirect.com/science/article/pii/S2667290126000483
  3. Nov 2026
  4. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Synthesis and Biological Evaluation of 5-Arylpyrazoles as Potential MCT 1 Inhibitors Targeting Lactate Transport
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cmdc.70555
  5. Oct 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uncovering MYOF as a novel therapeutic target in glioblastoma: mechanistic insights and drug discovery
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    pmc.ncbi.nlm.nih.gov/articles/PMC13645784/
  7. Aug 2026
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    Repurposing Nelfinavir: AIM2 inflammasome-associated anti-tumor effects in Glioblastoma
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    sciencedirect.com/science/article/pii/S0925443926002942
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    COPS7B Drives Malignant Progression of Glioblastoma Through Translational Upregulation of the Downstream Functional Effector CLU
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    pmc.ncbi.nlm.nih.gov/articles/PMC13467472/
  10. www.biorxiv.org www.biorxiv.org
    NLRP12-mediated Glioblastoma-Astrocyte Cross-talk Promotes Tumor Growth
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    biorxiv.org/content/10.1101/2025.11.13.688374v1
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A novel oncolytic herpes simplex virus type 2 induces polarization of tumor-associated macrophages and remodels the immune microenvironment in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13442803/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring Disulfide Bridge as a Tool to Improve Pioglitazone’s Neuroprotective Potential: Toward the Development of Prolonged‐Acting MAO‐B/PPARγ Modulators
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    pmc.ncbi.nlm.nih.gov/articles/PMC13420967/
  13. Jul 2026
  14. aacrjournals.org aacrjournals.org
    Oncolytic HSV-1-Mediated JAG1 Blockade Induces Glioma Senescence-Associated Secretory Phenotype to Increase Macrophage Activation and Cetuximab-Mediated Senolysis
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    aacrjournals.org/cancerres/article/86/5/1232/774877/Oncolytic-HSV-1-Mediated-JAG1-Blockade-Induces
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    Lactate binds and inhibits the innate immune sensor STING to promote tumor immune evasion
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    sciencedirect.com/science/article/pii/S1074761326002554
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    Feasibility and optimal imaging time window for intraperitoneal versus intravenous injection of a macrocyclic gadolinium-based contrast agent in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13319980/
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    Potent Anti-Glioblastoma Effects of Next-Generation MNK Inhibitors
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  18. Jun 2026
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    Small-molecule inhibitors of the protein kinase DYRK as potential therapeutic candidates in cancer
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    sciencedirect.com/science/article/pii/S2451945626001571
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    A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose-driven glioblastoma
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70274
  21. May 2026
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CREsted: modeling genomic and synthetic cell-type-specific enhancers across tissues and species
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    pmc.ncbi.nlm.nih.gov/articles/PMC13167471/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AI-driven network pharmacology and multi-omics validation identify KCNH2 as a prognostic biomarker and candidate therapeutic vulnerability of Acorus tatarinowii in glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13149083/
  24. Apr 2026
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    ACYP2 induces temozolomide resistance in glioblastoma by promoting PARP1-mediated DNA damage repair
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    aacrjournals.org/mcr/article/24/1/7/771152/ACYP2-Induces-Temozolomide-Resistance-in
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    mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL-tocopherol uptake pathway
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  27. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    JOSD1 Deubiquitinates Twist1 and Facilitates Epithelial–Mesenchymal Transition in Glioblastoma
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    Combined inactivation of MEK and mTOR can lead to synergistic cell death in glioblastoma models and associates with NF1-deficiency and a mesenchymal subtype
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  30. Mar 2026
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Innate Immune Receptor NLRX1: Potential Modulator of Glioblastoma Pathophysiology
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    onlinelibrary.wiley.com/doi/10.1002/jcp.70163
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    Rap1b promotes glioma growth and stemness via regulation of Notch1 and VEGFR2 signaling pathways
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    sciencedirect.com/science/article/pii/S0898656826001075
  33. Feb 2026
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repurposing the DNA Labeling Agent EdU for Therapy Against Heterogeneous Patient Glioblastoma
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  35. Jan 2026
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    Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
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    CRISPR activation screens map the genomic landscape of cancer glycome remodeling
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    Targeted degradation of CD24 by a transferrin receptor-engaging bispecific degrader enhances antitumor immunity
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  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High‐Throughput 3D Glioblastoma Model in Glycosaminoglycan Hydrogels for Personalized Therapeutic Screening
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    Lipid Droplet-Localized Spindle Apparatus Coiled-Coil Protein 1 Regulates Lipid Droplet Distribution
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511960
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    PRSS23 orchestrates nonclassical ferroptosis resistance in glioblastoma by modulating chromatin accessibility via the NCAPD3/YY1/MBOAT2 axis
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    Nanotherapy Targeting miR-10b Improves Survival in Orthotopic Glioblastoma Models
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    Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F-Actin Formation and Facilitate Double-strand DNA Breaks Repair in TMZ-Resistant Glioblastoma
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  44. Dec 2025
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    CUDC-907 inhibits glioblastoma and enhances glioblastoma sensitivity to temozolomide by inhibiting DNA damage repair
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  47. Nov 2025
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic potential of valsartan in overcoming chemoresistance in human glioblastoma
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  49. www.biorxiv.org www.biorxiv.org
    Repurposing Nelfinavir: AIM2 Inflammasome-Driven Anti-tumor Effects in Glioblastoma
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  50. Oct 2025
  51. www.biorxiv.org www.biorxiv.org
    Combinatorial Treatment of Glioblastoma with Temozolomide (TMZ) Plus 5-Ethynyl-2’-deoxyuridine (EdU)
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    biorxiv.org/content/10.1101/2025.10.21.683081v2
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    Development of retinoid nuclear receptor pathway antagonists through targeting aldehyde dehydrogenase 1A3
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    Coronin 1 Loss in Tumor Cells of Glioblastoma Patients Leads to Enhanced Tumor Aggressiveness
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.70261
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    An optimized click chemistry method allows visualization of proliferating neuronal progenitors in the mouse brain
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    “Cytochrome P450 2B6 Downregulation by Cell-Penetrating Dominant-Negative ATF5 Peptide in Glioblastoma Cells.”
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  56. Sep 2025
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    mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport
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  58. Jul 2025
  59. link.springer.com link.springer.com
    Tunneling nanotubes between glioblastoma cells and T cells and hijack of mitochondria
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    CLOCK promotes proliferation of glioblastoma cells through acetylating PRPS1/2
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    Cell Settling, Migration, and Stochastic Cancer Expression Suggest Potassium Flux Per H+- Sensitive KCN Members Associated with Oncogenes and Histone/DNA Modulators Potentially Initiates pH-Reversal
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  63. aacrjournals.org aacrjournals.org
    The DRD2 antagonist haloperidol mediates autophagy-induced ferroptosis to increase temozolomide sensitivity by promoting endoplasmic reticulum stress in glioblastoma
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    aacrjournals.org/clincancerres/article/29/16/3172/728242/The-DRD2-Antagonist-Haloperidol-Mediates-Autophagy
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    The GD3 ganglioside promotes cell growth, plasticity and chemotherapy resistance of human glioblastoma cancer stem cells
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  65. May 2025
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapy-induced senescence of glioblastoma cells is determined by the p21CIP1-CDK1/2 axis and does not require activation of DREAM
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  67. Apr 2025
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    A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function
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  70. Mar 2025
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    PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth
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    7 I, a structurally modified sinomenine, exerts dual anti-GBM effects by inhibiting glioblastoma proliferation and inducing necroptosis which further mediates lysosomal cell death
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17464
  73. Feb 2025
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel B7-H3 CAR T cells show potent antitumor effects in glioblastoma: a preclinical study
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    Novel Pannexin 1 isoform is increased in cancer
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  76. Jan 2025
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4
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    pmc.ncbi.nlm.nih.gov/articles/PMC11747271/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Involvement of p38 MAPK and MAPKAPK2 in promoting cell death and the inflammatory response to ischemic stress associated with necrotic glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11729867/
  79. Dec 2024
  80. www.nature.com www.nature.com
    Inhibition of thioredoxin reductase 1 sensitizes glucose-starved glioblastoma cells to disulfidptosis
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    nature.com/articles/s41418-024-01440-0
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    Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host
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    sciencedirect.com/science/article/pii/S1535610824004471
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    mLumiOpto Is a Mitochondrial-Targeted Gene Therapy for Treating Cancer
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    Neuron-Like Lineage Differentiation Induced by Exogenous Neurexin-1 as a Potential Therapeutic Strategy for Glioma
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    Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
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  85. Nov 2024
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    The cell cycle inhibitor p21CIP1 is essential for irinotecan-induced senescence and plays a decisive role in re-sensitization of temozolomide-resistant glioblastoma cells to irinotecan
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  87. Oct 2024
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    HOXDeRNA activates a cancerous transcription program and super enhancers via genome-wide binding
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  89. Sep 2024
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Function of a complex of p-Y42 RhoA GTPase and pyruvate kinase M2 in EGF signaling pathway in glioma cells
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16210
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    Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastoma
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  92. Aug 2024
  93. hereditasjournal.biomedcentral.com hereditasjournal.biomedcentral.com
    A potential immunotherapeutic and prognostic biomarker for multiple tumors including glioma: SHOX2
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    Comprehensive Analysis of the Clinical and Biological Significances of Endoplasmic Reticulum Stress in Diffuse Gliomas
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    frontiersin.org/articles/10.3389/fcell.2021.619396/full
  95. Jul 2024
  96. www.sciencedirect.com www.sciencedirect.com
    Near-infrared II fluorescence-guided glioblastoma surgery targeting monocarboxylate transporter 4 combined with photothermal therapy
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    sciencedirect.com/science/article/pii/S2352396424002792
  97. Feb 2024
  98. inflammregen.biomedcentral.com inflammregen.biomedcentral.com
    Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation
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    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
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    Migrasomal autophagosomes relieve endoplasmic reticulum stress in glioblastoma cells
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  102. Jan 2024
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intranasal Delivery of Oncolytic Adenovirus XVir-N-31 via Optimized Shuttle Cells Significantly Extends Survival of Glioblastoma-Bearing Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10605419/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
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  106. Dec 2023
  107. www.nature.com www.nature.com
    Jagged1 intracellular domain/SMAD3 complex transcriptionally regulates TWIST1 to drive glioma invasion
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    nature.com/articles/s41419-023-06356-0
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  109. Nov 2023
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    Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis
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  111. Oct 2023
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  113. Sep 2023
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  123. Oct 2022
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  133. Jul 2022
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  153. Aug 2021
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  156. Jul 2021
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  159. Jun 2021
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  167. Feb 2021
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  173. Sep 2020
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  179. Jan 2020
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