158 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666318/
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Off-pore nucleoporin sPOM121 transcriptionally propels β-Catenin driven tumor progression and immune escape in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580793/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased ErbB2 signaling is an early adaptation to androgen signaling inhibition and persists in castration resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12580767/
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integrated Analysis of Single-Cell RNA Sequencing and Machine Learning Reveals a T Cell-Specific PANoptosis Signature Predicting Prognosis and Immunotherapy in Prostate Cancer
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    onlinelibrary.wiley.com/doi/full/10.1155/humu/8889021
  7. Oct 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mistletoe Extracts Inhibit Progressive Growth of Prostate Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523822/
  9. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  10. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202511349
  11. www.science.org www.science.org
    Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer
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    science.org/doi/10.1126/scisignal.adu7145
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated Omics and Multi-Cohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485374/
  13. Sep 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KBTBD11 loss promotes AKT hyperactivation and therapeutic vulnerability in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12559007/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PDGFC facilitates enzalutamide resistance in prostate cancer through activation of the Rap1-MAPK pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12460851/
  16. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  17. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Enzalutamide-Resistant STEAP4+ MyoCAF Secrete Phosphatidylcholine to Foster Progression by Activating Stemness in Hormone-Sensitive Prostate Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202510602
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor associated neutrophils promote prostate cancer progression by mediating neutrophil trap secretion through PSMA1- NF-κB-HIF-1α signaling axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399615/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398604/
  20. Aug 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12358827/
  22. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    EGFR-STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1-positive prostate cancer
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70069
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322260/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
  26. www.sciencedirect.com www.sciencedirect.com
    Pharmacodynamic analyses of LAT1 inhibitors in vitro and in vivo by targeted metabolomics reveal target-independent effects
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    sciencedirect.com/science/article/pii/S0753332225005967
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AR+TREM2+ macrophage induced pathogenic immunosuppression promotes prostate cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12307935/
  28. Jul 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAF-mediated regulation of prostate cancer stem cell stemness via the Wnt/β-catenin and SDF-1/CXCR4 pathways in castration-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12303950/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Applying Unbiased, Functional Criteria Allows Selection of Novel Cyclic Peptides for Effective Targeted Drug Delivery to Malignant Prostate Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12298539/
  31. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
  32. www.science.org www.science.org
    Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors
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    science.org/doi/10.1126/sciadv.adw5228
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260511/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12234718/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in
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    pmc.ncbi.nlm.nih.gov/articles/PMC12224093/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12209829/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695179/
  38. Jun 2025
  39. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70049
  40. 52.53.155.43 52.53.155.43
    CTHRC1 promotes bone metastasis in prostate cancer
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    52.53.155.43/f04071ff6077a40bb108a3f03adfcb4d864028a7/Intl Journal of Cancer - 2025 - Sawada - CTHRC1 promotes bone metastasis in prostate cancer-html.html
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    Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
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    sciencedirect.com/science/article/pii/S2451945625001734
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  43. pubs.acs.org pubs.acs.org
    Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived Streptomyces mirabilis P8-A2
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    pubs.acs.org/doi/full/10.1021/acs.jnatprod.4c00029
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Downregulation of NONO Suppresses Proliferation, Migration, and Invasion in Metastatic Prostate Cancer
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    onlinelibrary.wiley.com/doi/10.1002/pros.24925
  45. link.springer.com link.springer.com
    Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate
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    link.springer.com/article/10.1186/s10020-025-01292-5
  46. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70073
  47. www.mdpi.com www.mdpi.com
    A Novel Primary Cell Line Model of Localized Prostate Cancer and Radioresistance—A Role for Nicotinamide N-Methyltransferase
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    mdpi.com/2073-4409/14/11/819
  48. May 2025
  49. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70065
  50. elifesciences.org elifesciences.org
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    elifesciences.org/reviewed-preprints/106511
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12019391/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11091964/
  54. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic and anti-migratory effects of Ocimum gratissimum L. essential oil on prostate and cervical cancer cells in vitro
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    sciencedirect.com/science/article/pii/S2667031325000909
  55. Apr 2025
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11870442/
  57. aacrjournals.org aacrjournals.org
    Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities
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    aacrjournals.org/mcr/article/23/4/327/754237/Exploring-B7-H4-s-Role-in-Prostate-Cancer-Dormancy
  58. 52.53.155.43 52.53.155.43
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  60. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Adenosine A3 receptor antagonists as anti-tumor treatment in human prostate cancer: an in vitro study
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.70024
  61. www.sciencedirect.com www.sciencedirect.com
    Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer
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    sciencedirect.com/science/article/pii/S0925443925000675
  62. Mar 2025
  63. www.sciencedirect.com www.sciencedirect.com
    Increased N-glycosylation of PSMA by GnT-V enhances tumor malignancy through interacting with JAK2 and the subsequent STAT3-mediated transcriptional activation in prostate cancer
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    sciencedirect.com/science/article/pii/S0141813025027904
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secretome Analysis of Prostate Cancer Cell Lines Reveals Cell Cycle-Dependent PSA Secretion and Potential Biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11899065/
  65. Feb 2025
  66. aacrjournals.org aacrjournals.org
    Preclinical efficacy of a PSMA-targeted actinium-225 conjugate (225Ac-macropa-pelgifatamab) - a targeted alpha therapy for prostate cancer
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    aacrjournals.org/clincancerres/article/30/11/2531/745373/Preclinical-Efficacy-of-a-PSMA-Targeted-Actinium
  67. Jan 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774231/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11771886/
  70. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Clinical significance of stratifying prostate cancer patients through specific circulating genes
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13805
  71. 52.53.155.43 52.53.155.43
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  72. Dec 2024
  73. 52.53.155.43 52.53.155.43
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  74. pubs.acs.org pubs.acs.org
    Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1
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    pubs.acs.org/doi/10.1021/acsami.4c15472
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612623/
  76. Nov 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anoikis in prostate cancer bone metastasis gene signatures and therapeutic implications
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    ncbi.nlm.nih.gov/pmc/articles/PMC11464922/
  78. Oct 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis revealing the metabolic landscape of prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11449408/
  80. Sep 2024
  81. www.sciencedirect.com www.sciencedirect.com
    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
  82. Aug 2024
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306513/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  85. www.sciencedirect.com www.sciencedirect.com
    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
  86. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13703
  87. Jul 2024
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating miR-6880-5p in extracellular vesicle from plasma as a prognostic biomarker in endocrine therapy-treated castration-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285227/
  89. www.biorxiv.org www.biorxiv.org
    Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
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    biorxiv.org/content/10.1101/2024.07.09.602803v1
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11237870/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identify Regulatory eQTLs by Multiome Sequencing in Prostate Single Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213234/
  92. Jun 2024
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen-responsive FOXP4 is a target for endometrial carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11189448/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The androgen receptor does not directly regulate the transcription of DNA damage response genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022999/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sialic acid blockade inhibits the metastatic spread of prostate cancer to bone
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    ncbi.nlm.nih.gov/pmc/articles/PMC11134892/
  96. Apr 2024
  97. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13653
  98. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERBB3 overexpression is enriched in diverse patient populations with castration-sensitive prostate cancer and is associated with a unique AR activity signature
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016893/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CB307: A Dual Targeting Costimulatory Humabody VH Therapeutic for Treating PSMA-Positive Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016891/
  101. Mar 2024
  102. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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  110. Jan 2024
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  113. Dec 2023
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  116. Nov 2023
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  121. Oct 2023
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  124. Sep 2023
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  126. Aug 2023
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  130. May 2023
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  136. Mar 2023
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  139. Feb 2023
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  141. Dec 2022
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  145. Aug 2022
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  149. Jul 2022
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  151. May 2022
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  154. Apr 2022
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  157. Mar 2022
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  161. Nov 2021
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  163. Sep 2021
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  165. Aug 2021
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  169. Jul 2021
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  171. Jun 2021
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  173. May 2021
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  179. Apr 2021
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  181. Feb 2021
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  184. Jan 2021
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  188. Nov 2020
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  190. Oct 2020
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  192. Sep 2020
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  200. Jan 2020
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  203. Nov 2017
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