154 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mistletoe Extracts Inhibit Progressive Growth of Prostate Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12523822/
  3. Oct 2025
  4. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  5. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Laeverin is Cell-Surface Target for Liquid-Phase Metastasizing Cancer Cells
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202511349
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    Defining the MYC-regulated transcriptome and kinome that support KRAS- and ERK-dependent growth of pancreatic cancer
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    science.org/doi/10.1126/scisignal.adu7145
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated Omics and Multi-Cohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485374/
  8. Sep 2025
  9. www.nature.com www.nature.com
    KBTBD11 loss promotes AKT hyperactivation and therapeutic vulnerability in prostate cancer
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    nature.com/articles/s41388-025-03576-w
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PDGFC facilitates enzalutamide resistance in prostate cancer through activation of the Rap1-MAPK pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC12460851/
  11. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  12. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Enzalutamide-Resistant STEAP4+ MyoCAF Secrete Phosphatidylcholine to Foster Progression by Activating Stemness in Hormone-Sensitive Prostate Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202510602
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    Tumor associated neutrophils promote prostate cancer progression by mediating neutrophil trap secretion through PSMA1- NF-κB-HIF-1α signaling axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399615/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In-cell proximity target validation methods for heterobifunctional molecules with CRBN- or VHL-binder using AirID
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398604/
  15. Aug 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients
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    pmc.ncbi.nlm.nih.gov/articles/PMC12358827/
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    EGFR-STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1-positive prostate cancer
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70069
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
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    Pharmacodynamic analyses of LAT1 inhibitors in vitro and in vivo by targeted metabolomics reveal target-independent effects
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    sciencedirect.com/science/article/pii/S0753332225005967
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AR+TREM2+ macrophage induced pathogenic immunosuppression promotes prostate cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12307935/
  23. Jul 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAF-mediated regulation of prostate cancer stem cell stemness via the Wnt/β-catenin and SDF-1/CXCR4 pathways in castration-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12303950/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Applying Unbiased, Functional Criteria Allows Selection of Novel Cyclic Peptides for Effective Targeted Drug Delivery to Malignant Prostate Cancer Cells
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  26. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
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    Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors
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    science.org/doi/10.1126/sciadv.adw5228
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260511/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer
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  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in
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  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical Context Shapes the Relationship between Genomic Alterations and Response to AR Inhibitors and Chemotherapy in Metastatic Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12209829/
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695179/
  33. Jun 2025
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    CTHRC1 promotes bone metastasis in prostate cancer
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    Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
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    Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived Streptomyces mirabilis P8-A2
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    pubs.acs.org/doi/full/10.1021/acs.jnatprod.4c00029
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    Downregulation of NONO Suppresses Proliferation, Migration, and Invasion in Metastatic Prostate Cancer
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    onlinelibrary.wiley.com/doi/10.1002/pros.24925
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    Targeted destruction of follicle stimulating hormone receptor-positive cancer cells in vitro and in vivo by a lytic peptide Phor21-FSHβ conjugate
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    link.springer.com/article/10.1186/s10020-025-01292-5
  41. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70073
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    A Novel Primary Cell Line Model of Localized Prostate Cancer and Radioresistance—A Role for Nicotinamide N-Methyltransferase
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  43. May 2025
  44. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  45. elifesciences.org elifesciences.org
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    elifesciences.org/reviewed-preprints/106511
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12019391/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11091964/
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    Cytotoxic and anti-migratory effects of Ocimum gratissimum L. essential oil on prostate and cervical cancer cells in vitro
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    sciencedirect.com/science/article/pii/S2667031325000909
  50. Apr 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11870442/
  52. aacrjournals.org aacrjournals.org
    Exploring B7-H4’s Role in Prostate Cancer Dormancy after Androgen Deprivation Therapy: Extracellular Matrix Interactions and Therapeutic Opportunities
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    aacrjournals.org/mcr/article/23/4/327/754237/Exploring-B7-H4-s-Role-in-Prostate-Cancer-Dormancy
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    Adenosine A3 receptor antagonists as anti-tumor treatment in human prostate cancer: an in vitro study
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.70024
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    Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer
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    sciencedirect.com/science/article/pii/S0925443925000675
  57. Mar 2025
  58. www.sciencedirect.com www.sciencedirect.com
    Increased N-glycosylation of PSMA by GnT-V enhances tumor malignancy through interacting with JAK2 and the subsequent STAT3-mediated transcriptional activation in prostate cancer
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    sciencedirect.com/science/article/pii/S0141813025027904
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secretome Analysis of Prostate Cancer Cell Lines Reveals Cell Cycle-Dependent PSA Secretion and Potential Biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11899065/
  60. Feb 2025
  61. aacrjournals.org aacrjournals.org
    Preclinical efficacy of a PSMA-targeted actinium-225 conjugate (225Ac-macropa-pelgifatamab) - a targeted alpha therapy for prostate cancer
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    aacrjournals.org/clincancerres/article/30/11/2531/745373/Preclinical-Efficacy-of-a-PSMA-Targeted-Actinium
  62. Jan 2025
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774231/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11771886/
  65. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Clinical significance of stratifying prostate cancer patients through specific circulating genes
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13805
  66. 52.53.155.43 52.53.155.43
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  67. Dec 2024
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  69. pubs.acs.org pubs.acs.org
    Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1
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    pubs.acs.org/doi/10.1021/acsami.4c15472
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612623/
  71. Nov 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anoikis in prostate cancer bone metastasis gene signatures and therapeutic implications
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    ncbi.nlm.nih.gov/pmc/articles/PMC11464922/
  73. Oct 2024
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis revealing the metabolic landscape of prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11449408/
  75. Sep 2024
  76. www.sciencedirect.com www.sciencedirect.com
    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
  77. Aug 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306513/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  80. www.sciencedirect.com www.sciencedirect.com
    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
  81. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13703
  82. Jul 2024
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Investigating miR-6880-5p in extracellular vesicle from plasma as a prognostic biomarker in endocrine therapy-treated castration-resistant prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285227/
  84. www.biorxiv.org www.biorxiv.org
    Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
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    biorxiv.org/content/10.1101/2024.07.09.602803v1
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11237870/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identify Regulatory eQTLs by Multiome Sequencing in Prostate Single Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11213234/
  87. Jun 2024
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen-responsive FOXP4 is a target for endometrial carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11189448/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The androgen receptor does not directly regulate the transcription of DNA damage response genes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11022999/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sialic acid blockade inhibits the metastatic spread of prostate cancer to bone
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    ncbi.nlm.nih.gov/pmc/articles/PMC11134892/
  91. Apr 2024
  92. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13653
  93. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERBB3 overexpression is enriched in diverse patient populations with castration-sensitive prostate cancer and is associated with a unique AR activity signature
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016893/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CB307: A Dual Targeting Costimulatory Humabody VH Therapeutic for Treating PSMA-Positive Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016891/
  96. Mar 2024
  97. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  98. www.nature.com www.nature.com
    Clinically-observed FOXA1 mutations upregulate SEMA3C through transcriptional derepression in prostate cancer
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    nature.com/articles/s41598-024-57854-w
  99. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Acetylated KHSRP impairs DNA-damage-response-related mRNA decay and facilitates prostate cancer tumorigenesis
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13634
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  101. Feb 2024
  102. 52.53.155.43 52.53.155.43
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  105. Jan 2024
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  108. Dec 2023
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  111. Nov 2023
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  116. Oct 2023
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  119. Sep 2023
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  121. Aug 2023
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  125. May 2023
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  131. Mar 2023
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  134. Feb 2023
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  136. Dec 2022
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  140. Aug 2022
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  144. Jul 2022
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  146. May 2022
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  149. Apr 2022
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  152. Mar 2022
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  156. Nov 2021
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  158. Sep 2021
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  160. Aug 2021
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  164. Jul 2021
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  166. Jun 2021
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  168. May 2021
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  174. Apr 2021
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  176. Feb 2021
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  179. Jan 2021
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  183. Nov 2020
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  185. Oct 2020
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  187. Sep 2020
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  195. Jan 2020
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  198. Nov 2017
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    Cellular Migration Ability Is Modulated by Extracellular Purines in Ovarian Carcinoma SKOV‐3 Cells
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