32 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    DHODH is a synthetic lethal target in PIK3CA-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124726007977
  3. Jun 2026
  4. www.sciencedirect.com www.sciencedirect.com
    Distinct ERK and PI3K dependencies mediate a heterogeneous response to RAS(ON) inhibition in KRAS-mutant colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124726006376
  5. May 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Visceral and subcutaneous adipose stem cells modulate colorectal cancer cell progression: direct and indirect contact distinctly accelerate tumor aggressiveness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13130794/
  7. Mar 2026
  8. www.sciencedirect.com www.sciencedirect.com
    Intratumoral microbiota and host genotype cooperatively shape neutrophil cytotoxic functions in colorectal cancer
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    sciencedirect.com/science/article/pii/S193131282600051X
  9. Dec 2025
  10. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R-Loop Accumulation and DNA Repair Deficiencies
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202512074
  11. Nov 2025
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    Paneth-like transition drives resistance to dual targeting of KRAS and EGFR in colorectal cancer
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    sciencedirect.com/science/article/pii/S1535610825004519
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591322/
  14. Sep 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GALNT7 stratifies dMMR/MSI colorectal cancer into distinct molecular subsets associated with prognosis and PD-L1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12412012/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11875910/
  17. Aug 2025
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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    sciencedirect.com/science/article/pii/S1535610825003101
  19. Jul 2025
  20. 52.53.155.43 52.53.155.43
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  21. Jun 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic mapping of the human solute carrier superfamily
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130231/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The solute carrier superfamily interactome
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130317/
  24. Apr 2025
  25. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225006649-main-html.html
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  26. Mar 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape
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    pmc.ncbi.nlm.nih.gov/articles/PMC11832170/
  28. Feb 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch Repair
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    pmc.ncbi.nlm.nih.gov/articles/PMC11831107/
  30. Jan 2025
  31. www.sciencedirect.com www.sciencedirect.com
    The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004896
  32. Dec 2024
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11601497/
  34. Oct 2024
  35. www.biorxiv.org www.biorxiv.org
    Metabolic mapping of the human solute carrier superfamily
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    biorxiv.org/content/10.1101/2024.09.23.614124v1
  36. Jul 2024
  37. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    sciencedirect.com/science/article/pii/S1535610824002174
  38. Apr 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases
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    sciencedirect.com/science/article/pii/S2666379124001927
  40. Jan 2024
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    A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization
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    sciencedirect.com/science/article/pii/S1535610823004440
  42. Jun 2023
  43. 52.53.155.43 52.53.155.43
    The ubiquitin E3 ligase MDM2 induces chemoresistance in colorectal cancer by degradation of ING3
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    52.53.155.43/fcf8eb638d53697aa65b86389d0e22b90374ae7c/bgad040 (1)-html.html
  44. Jun 2022
  45. 52.53.155.43 52.53.155.43
    cd-21-0680-html.html
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  46. Jan 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AP-2α Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8254761/
  48. Sep 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Oncogene-dependent sloppiness in mRNA translation
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    sciencedirect.com/science/article/pii/S109727652100736X
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of synergistic transcriptional feedback loops drives diverse B-cell cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC8403728/
  51. Aug 2021
  52. elifesciences.org elifesciences.org
    Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy
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    elifesciences.org/articles/27301
  53. Sep 2020
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cotargeting BET proteins overcomes resistance arising from PI3K/mTOR blockade‐induced protumorigenic senescence in colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33047
  55. Nov 2017
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases
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    ncbi.nlm.nih.gov/pmc/articles/PMC5224920/