103 Matching Annotations
  1. Aug 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12406974/
  3. www.biorxiv.org www.biorxiv.org
    ZYS-1 is not an ADAR1 inhibitor
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    biorxiv.org/content/10.1101/2025.08.08.669362v2
  4. Jul 2025
  5. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225013823-main-html.html
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  6. www.sciencedirect.com www.sciencedirect.com
    Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002915
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint Therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214883/
  8. aacrjournals.org aacrjournals.org
    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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    aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
  9. Jun 2025
  10. www.sciencedirect.com www.sciencedirect.com
    Metastatic breast cancer cells adapt to a soft environment with limited involvement of mechanotransduction
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    sciencedirect.com/science/article/pii/S0014482725002253
  11. May 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    αB-crystallin enhances radioresistance in basal-like breast cancer cells by suppressing caspase-3 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12092982/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the LINE1-derived MET transcript induces apoptosis and oncoprotein knockdown in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12032326/
  14. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225007849-main-html.html
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  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High expression of miR-7974 predicts poor prognosis and is associated with autophagy in estrogen receptor-positive breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12040258/
  16. link.springer.com link.springer.com
    Microtubule associated serine/threonine kinase-3 inhibits the malignant phenotype of breast cancer by promoting phosphorylation-mediated ubiquitination degradation of yes-associated protein
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    link.springer.com/article/10.1186/s13058-025-02028-3
  17. Apr 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11959274/
  19. Feb 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  21. 52.53.155.43 52.53.155.43
    ccr-24-2669-html.html
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  22. Jan 2025
  23. link.springer.com link.springer.com
    GLUT1 as a generic biomarker enables near-infrared fluorescence molecular imaging guided precise intraoperative tumor detection in breast cancer
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    link.springer.com/article/10.1007/s00259-025-07095-4
  24. www.sciencedirect.com www.sciencedirect.com
    OSMOTIC STRESS INFLUENCES MICROTUBULE DRUG RESPONSE VIA WNK1 KINASE SIGNALING
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    sciencedirect.com/science/article/pii/S1368764625000032
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35271
  26. Nov 2024
  27. www.sciencedirect.com www.sciencedirect.com
    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004434
  28. Sep 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11403291/
  30. www.sciencedirect.com www.sciencedirect.com
    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
  31. Aug 2024
  32. 52.53.155.43 52.53.155.43
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  33. Jul 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles
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    sciencedirect.com/science/article/pii/S2589004224016869
  35. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  36. www.biorxiv.org www.biorxiv.org
    Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
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    biorxiv.org/content/10.1101/2024.07.08.602030v1
  37. www.mdpi.com www.mdpi.com
    Define Critical Parameters of Trastuzumab-Mediated ADCC Assays via Assay Optimization Processes, Focusing on the Impact of Cryopreserved Effector Cells on Assay Performance
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    mdpi.com/2072-6694/16/13/2367
  38. Jun 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPX2 overexpression promotes sensitivity to dasatinib in breast cancer by activating YAP transcriptional signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161735/
  40. May 2024
  41. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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    nature.com/articles/s41416-024-02697-5
  42. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  43. aacrjournals.org aacrjournals.org
    Spatiotemporal quantification of HER2-targeting antibody-drug conjugate bystander activity and enhancement of solid tumor penetration
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    aacrjournals.org/clincancerres/article/30/5/984/734305/Spatiotemporal-Quantification-of-HER2-targeting
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078187/
  45. www.science.org www.science.org
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    science.org/doi/10.1126/sciadv.adj1468
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811747/
  47. Apr 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AIbZIP/CREB3L4 Promotes Cell Proliferation via the SKP2-p27 Axis in Luminal Androgen Receptor Subtype Triple Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10985479/
  49. Mar 2024
  50. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10945736/
  52. Feb 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  54. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
  55. www.sciencedirect.com www.sciencedirect.com
    Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR
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    sciencedirect.com/science/article/pii/S1534580724000303
  56. www.sciencedirect.com www.sciencedirect.com
    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124000053
  57. Jan 2024
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-essential amino acid availability influences proteostasis and breast cancer cell survival during proteotoxic stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10330057/
  59. Dec 2023
  60. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  61. Nov 2023
  62. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
  63. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004223023684-main-html.html
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  64. Oct 2023
  65. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/dbe8c3e3fbcbeef5c4f8f35843262b8cfb5dca0c/Molecular Oncology - 2023 - Liu - USP7 reduces the level of nuclear DICER impairing DNA damage response and promoting-html.html
  66. Sep 2023
  67. link.springer.com link.springer.com
    Use of Native-PAGE for the Identification of Epichaperomes in Cell Lines
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    link.springer.com/protocol/10.1007/978-1-0716-3342-7_14
  68. www.sciencedirect.com www.sciencedirect.com
    Natural killer cell therapy targeting cancer stem cells: Old wine in a new bottle
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    sciencedirect.com/science/article/pii/S0304383523002793
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10481131/
  70. Jul 2023
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10368911/
  72. 52.53.155.43 52.53.155.43
    cd-23-0475-html.html
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    52.53.155.43/ab02200bf4457c1e8196af2525f73574a3d0dd99/cd-23-0475-html.html
  73. 52.53.155.43 52.53.155.43
    Non-essential amino acid availability influences proteostasis and breast cancer cell survival during proteotoxic stress.
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    52.53.155.43/3b61077c408fa930bcc14a1de6934f9bf36eeaba/mcr-22-0843-html.html
  74. Jun 2023
  75. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  76. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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    aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
  77. May 2023
  78. link.springer.com link.springer.com
    ZNRF2 as an oncogene is transcriptionally regulated by CREB1 in breast cancer models
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    link.springer.com/article/10.1007/s13577-023-00913-7
  79. www.spandidos-publications.com www.spandidos-publications.com
    Targeting the Vav1/miR‑29b axis as a potential approach for treating selected molecular subtypes of triple‑negative breast cancer
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    spandidos-publications.com/10.3892/or.2021.8034
  80. Apr 2023
  81. www.nature.com www.nature.com
    LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism
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    nature.com/articles/s41467-023-37871-5
  82. Oct 2022
  83. link.springer.com link.springer.com
    Shrimp miR-965 transfers tumoricidal mitochondria
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    link.springer.com/article/10.1186/s12575-022-00178-8
  84. aacrjournals.org aacrjournals.org
    An enzymatically cleavable tripeptide linker for maximizing the therapeutic index of antibody-drug conjugates
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    aacrjournals.org/mct/article/21/9/1449/708807/An-Enzymatically-Cleavable-Tripeptide-Linker-for
  85. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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    sciencedirect.com/science/article/pii/S1550413122004119
  86. Aug 2022
  87. 52.53.155.43 52.53.155.43
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  88. Mar 2022
  89. aacrjournals.org aacrjournals.org
    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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    aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfate-dependent RAGE oligomerization is indispensable for pathophysiological functions of RAGE
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    ncbi.nlm.nih.gov/pmc/articles/PMC8863369/
  91. www.sciencedirect.com www.sciencedirect.com
    Proteome-centric cross-omics characterization and integrated network analyses of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124722001875
  92. Jan 2022
  93. www.nature.com www.nature.com
    FTY720 in resistant human epidermal growth factor receptor 2-positive breast cancer
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    nature.com/articles/s41598-021-04328-y
  94. www.dovepress.com www.dovepress.com
    <p>Dynamics of Endocytosis and Degradation of Antibody-Drug Conjugate T-DM1 in HER2 Positive Cancer Cells</p>
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    dovepress.com/dynamics-of-endocytosis-and-degradation-of-antibody-drug-conjugate-t-d-peer-reviewed-fulltext-article-DDDT
  95. Nov 2021
  96. www.sciencedirect.com www.sciencedirect.com
    GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12
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    sciencedirect.com/science/article/pii/S2589004221012803
  97. www.sciencedirect.com www.sciencedirect.com
    Antibody-Drug Conjugate and Free Geldanamycin Combination Therapy Enhances Anti-Cancer Efficacy
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    sciencedirect.com/science/article/pii/S0378517321010784
  98. Sep 2021
  99. www.sciencedirect.com www.sciencedirect.com
    RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy
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    sciencedirect.com/science/article/pii/S193459092100343X
  100. Aug 2021
  101. www.sciencedirect.com www.sciencedirect.com
    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S2405471219303874
  102. Jul 2021
  103. www.sciencedirect.com www.sciencedirect.com
    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
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    sciencedirect.com/science/article/pii/S2451945619303629
  104. www.sciencedirect.com www.sciencedirect.com
    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719311313
  105. elifesciences.org elifesciences.org
    Synergistic interactions with PI3K inhibition that induce apoptosis
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    elifesciences.org/articles/24523
  106. www.sciencedirect.com www.sciencedirect.com
    Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
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    sciencedirect.com/science/article/pii/S221112471831667X
  107. link.springer.com link.springer.com
    ARA-linker-TGFαL3: a novel chimera protein to target breast cancer cells
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    link.springer.com/article/10.1007/s12032-021-01546-2
  108. May 2021
  109. www.sciencedirect.com www.sciencedirect.com
    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    sciencedirect.com/science/article/pii/S1097276520305815
  110. www.sciencedirect.com www.sciencedirect.com
    Deciphering the signaling network of breast cancer improves drug sensitivity prediction
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    sciencedirect.com/science/article/pii/S2405471221001113
  111. Apr 2021
  112. www.sciencedirect.com www.sciencedirect.com
    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    sciencedirect.com/science/article/pii/S1550413120305453
  113. Feb 2021
  114. academic.oup.com academic.oup.com
    A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-Negative Breast Cancer Anoikis Resistance
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    academic.oup.com/endo/article/162/2/bqaa226/6027912
  115. elifesciences.org elifesciences.org
    Synergistic interactions with PI3K inhibition that induce apoptosis
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    elifesciences.org/articles/24523
  116. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14985
  117. Oct 2020
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B
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    ncbi.nlm.nih.gov/pmc/articles/PMC7553775/
  119. www.cell.com www.cell.com
    Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
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    cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
  120. mcr.aacrjournals.org mcr.aacrjournals.org
    Elevated V-ATPase activity following PTEN loss is required for enhanced oncogenic signaling in breast cancer
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  121. Sep 2020
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    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers
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    Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations
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    A Modified Lentivirus-Based Reporter for Magnetic Separation of Cancer Stem Cells
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    FGF13 promotes metastasis of triple‐negative breast cancer
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    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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  130. Jan 2020
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    Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis
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    VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
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    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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  135. Nov 2018
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    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
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    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
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  141. Nov 2017
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    GLUL Promotes Cell Proliferation in Breast Cancer
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