125 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    EZH2 Inhibitors Sensitize Breast Cancer to HER2 Kinase Inhibitors through Cooperative Effects on YAP and Pro-apoptotic Regulators
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    aacrjournals.org/cancerres/article/86/6/1467/775076/EZH2-Inhibitors-Sensitize-Breast-Cancer-to-HER2
  3. aacrjournals.org aacrjournals.org
    ZNF296 Drives Immune Evasion in Epithelial Cancers by Repressing Immune Stimulatory Genes
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    aacrjournals.org/cancerres/article/86/1/116/771155/ZNF296-Drives-Immune-Evasion-in-Epithelial-Cancers
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    Distinct metabolic dependency on BCAA defines cancer stemness and malignancy in human triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124726007084
  5. May 2026
  6. aacrjournals.org aacrjournals.org
    ZSTK3744, a novel aryl hydrocarbon receptor agonist, exhibits efficacy against chemotherapy-resistant triple-negative breast cancer
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    aacrjournals.org/cancerrescommun/article/6/2/421/774901/ZSTK3744-a-Novel-Aryl-Hydrocarbon-Receptor-Agonist
  7. Apr 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CircNSD2 promotes metastasis and immune escape by increasing the USP10/SRSF6-mediated alternative splicing of TPM1 in TNBC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13088798/
  9. link.springer.com link.springer.com
    The GATA3-RFPL3-ASK1 axis suppresses breast cancer growth and lung metastasis
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    link.springer.com/article/10.1007/s10495-026-02335-w
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metastasis-associated wound repair promotes reciprocal lung epithelium activation and breast cancer metastatic outgrowth
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    pmc.ncbi.nlm.nih.gov/articles/PMC13051055/
  11. www.nature.com www.nature.com
    AXL–SHC1 signaling axis mediates adaptive resistance to HER2-targeted tyrosine kinase inhibitors in HER2-aberrant lung and gastric cancers
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    nature.com/articles/s41698-026-01385-2
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptomic analysis to uncover the mechanism of radiosensitization of AR-positive triple-negative breast cancers with AR inhibition
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039478/
  13. Mar 2026
  14. www.sciencedirect.com www.sciencedirect.com
    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    sciencedirect.com/science/article/pii/S0092867426002692
  15. onlinelibrary.wiley.com onlinelibrary.wiley.com
    eFluor 450 Enables Superior Detection of Intracellular Staphylococcus aureus in High-Autofluorescence Triple-Negative Breast Cancer Cells
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    onlinelibrary.wiley.com/doi/10.1002/cyto.a.70019
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In vivo Auto-tuning of Antibody-Drug Conjugate Delivery to Maximize Efficacy using High-Avidity, Low-Affinity Antibodies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12964248/
  17. Feb 2026
  18. www.sciencedirect.com www.sciencedirect.com
    RAD51 succinylation regulates homologous recombination and contributes to the chemosensitivity in cancer
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    sciencedirect.com/science/article/pii/S1097276526000626
  19. Jan 2026
  20. www.sciencedirect.com www.sciencedirect.com
    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    sciencedirect.com/science/article/pii/S2666379125006500
  21. www.mdpi.com www.mdpi.com
    Cell-Penetrating Peptide-Mediated siRNA Targeting of LDHC Suppresses Tumor Growth in a Triple-Negative Breast Cancer Zebrafish Xenograft Model
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    mdpi.com/1999-4923/18/1/78
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    Calcium and Cadmium Activate ESRRB to Mediate Cell Stemness and Pluripotency
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    mdpi.com/1422-0067/27/1/231
  23. Dec 2025
  24. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    SNCA inhibits breast cancer progression through TP53AIP1–p53-mediated mitochondrial apoptosis and suppression of cancer stemness
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    sciencedirect.com:5037/science/article/pii/S2352304225004878
  25. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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    sciencedirect.com:5037/science/article/pii/S2666379125005518
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRF-21LeuTAA Promotes Oxidative Stress by Altering Glutathione Metabolic Enzymes to Support Prostate Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666318/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZYS-1 is not an ADAR1 inhibitor
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    pmc.ncbi.nlm.nih.gov/articles/PMC12621589/
  28. Nov 2025
  29. link.springer.com link.springer.com
    Mitophagy is responsible to ionizing radiation but plays a very limited role in the radiosensitivity of adenocarcinoma cells
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    link.springer.com/article/10.1007/s13577-025-01328-2
  30. Oct 2025
  31. www.sciencedirect.com www.sciencedirect.com
    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  32. Aug 2025
  33. www.cell.com www.cell.com
    RNA Pol II inhibition activates cell death independently from the loss of transcription
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    cell.com/cell/abstract/S0092-8674(25)00856-6
  34. www.biorxiv.org www.biorxiv.org
    ZYS-1 is not an ADAR1 inhibitor
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    biorxiv.org/content/10.1101/2025.08.08.669362v2
  35. Jul 2025
  36. 52.53.155.43 52.53.155.43
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    Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125002915
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint Therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214883/
  39. aacrjournals.org aacrjournals.org
    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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    aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
  40. Jun 2025
  41. www.sciencedirect.com www.sciencedirect.com
    Metastatic breast cancer cells adapt to a soft environment with limited involvement of mechanotransduction
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    sciencedirect.com/science/article/pii/S0014482725002253
  42. May 2025
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    αB-crystallin enhances radioresistance in basal-like breast cancer cells by suppressing caspase-3 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12092982/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of the LINE1-derived MET transcript induces apoptosis and oncoprotein knockdown in cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12032326/
  45. 52.53.155.43 52.53.155.43
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  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High expression of miR-7974 predicts poor prognosis and is associated with autophagy in estrogen receptor-positive breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12040258/
  47. link.springer.com link.springer.com
    Microtubule associated serine/threonine kinase-3 inhibits the malignant phenotype of breast cancer by promoting phosphorylation-mediated ubiquitination degradation of yes-associated protein
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    link.springer.com/article/10.1186/s13058-025-02028-3
  48. Apr 2025
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11959274/
  50. Feb 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  52. 52.53.155.43 52.53.155.43
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  53. Jan 2025
  54. link.springer.com link.springer.com
    GLUT1 as a generic biomarker enables near-infrared fluorescence molecular imaging guided precise intraoperative tumor detection in breast cancer
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    link.springer.com/article/10.1007/s00259-025-07095-4
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    OSMOTIC STRESS INFLUENCES MICROTUBULE DRUG RESPONSE VIA WNK1 KINASE SIGNALING
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    sciencedirect.com/science/article/pii/S1368764625000032
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35271
  57. Nov 2024
  58. www.sciencedirect.com www.sciencedirect.com
    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004434
  59. Sep 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergistic effects of PARP inhibition and cholesterol biosynthesis pathway modulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11403291/
  61. www.sciencedirect.com www.sciencedirect.com
    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
  62. Aug 2024
  63. 52.53.155.43 52.53.155.43
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  64. Jul 2024
  65. www.sciencedirect.com www.sciencedirect.com
    Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles
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    sciencedirect.com/science/article/pii/S2589004224016869
  66. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  67. www.biorxiv.org www.biorxiv.org
    Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling
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    biorxiv.org/content/10.1101/2024.07.08.602030v1
  68. www.mdpi.com www.mdpi.com
    Define Critical Parameters of Trastuzumab-Mediated ADCC Assays via Assay Optimization Processes, Focusing on the Impact of Cryopreserved Effector Cells on Assay Performance
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    mdpi.com/2072-6694/16/13/2367
  69. Jun 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPX2 overexpression promotes sensitivity to dasatinib in breast cancer by activating YAP transcriptional signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161735/
  71. May 2024
  72. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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    nature.com/articles/s41416-024-02697-5
  73. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  74. aacrjournals.org aacrjournals.org
    Spatiotemporal quantification of HER2-targeting antibody-drug conjugate bystander activity and enhancement of solid tumor penetration
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    aacrjournals.org/clincancerres/article/30/5/984/734305/Spatiotemporal-Quantification-of-HER2-targeting
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    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078187/
  76. www.science.org www.science.org
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    science.org/doi/10.1126/sciadv.adj1468
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBF-beta mitigates PI3K-alpha-specific inhibitor killing through PIM1 in PIK3CA mutant gastric cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10811747/
  78. Apr 2024
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AIbZIP/CREB3L4 Promotes Cell Proliferation via the SKP2-p27 Axis in Luminal Androgen Receptor Subtype Triple Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10985479/
  80. Mar 2024
  81. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heparan sulfate promotes TRAIL-induced tumor cell apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10945736/
  83. Feb 2024
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  85. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
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    Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR
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    sciencedirect.com/science/article/pii/S1534580724000303
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124000053
  88. Jan 2024
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-essential amino acid availability influences proteostasis and breast cancer cell survival during proteotoxic stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10330057/
  90. Dec 2023
  91. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  92. Nov 2023
  93. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
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  95. Oct 2023
  96. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/dbe8c3e3fbcbeef5c4f8f35843262b8cfb5dca0c/Molecular Oncology - 2023 - Liu - USP7 reduces the level of nuclear DICER impairing DNA damage response and promoting-html.html
  97. Sep 2023
  98. link.springer.com link.springer.com
    Use of Native-PAGE for the Identification of Epichaperomes in Cell Lines
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    link.springer.com/protocol/10.1007/978-1-0716-3342-7_14
  99. www.sciencedirect.com www.sciencedirect.com
    Natural killer cell therapy targeting cancer stem cells: Old wine in a new bottle
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    sciencedirect.com/science/article/pii/S0304383523002793
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10481131/
  101. Jul 2023
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10368911/
  103. 52.53.155.43 52.53.155.43
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    Non-essential amino acid availability influences proteostasis and breast cancer cell survival during proteotoxic stress.
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    52.53.155.43/3b61077c408fa930bcc14a1de6934f9bf36eeaba/mcr-22-0843-html.html
  105. Jun 2023
  106. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  107. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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    aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
  108. May 2023
  109. link.springer.com link.springer.com
    ZNRF2 as an oncogene is transcriptionally regulated by CREB1 in breast cancer models
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    link.springer.com/article/10.1007/s13577-023-00913-7
  110. www.spandidos-publications.com www.spandidos-publications.com
    Targeting the Vav1/miR‑29b axis as a potential approach for treating selected molecular subtypes of triple‑negative breast cancer
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    spandidos-publications.com/10.3892/or.2021.8034
  111. Apr 2023
  112. www.nature.com www.nature.com
    LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism
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    nature.com/articles/s41467-023-37871-5
  113. Oct 2022
  114. link.springer.com link.springer.com
    Shrimp miR-965 transfers tumoricidal mitochondria
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    link.springer.com/article/10.1186/s12575-022-00178-8
  115. aacrjournals.org aacrjournals.org
    An enzymatically cleavable tripeptide linker for maximizing the therapeutic index of antibody-drug conjugates
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    aacrjournals.org/mct/article/21/9/1449/708807/An-Enzymatically-Cleavable-Tripeptide-Linker-for
  116. www.sciencedirect.com www.sciencedirect.com
    Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
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    sciencedirect.com/science/article/pii/S1550413122004119
  117. Aug 2022
  118. 52.53.155.43 52.53.155.43
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  119. Mar 2022
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  123. Jan 2022
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  126. Nov 2021
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    GABAB1e promotes the malignancy of human cancer cells by targeting the tyrosine phosphatase PTPN12
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    Antibody-Drug Conjugate and Free Geldanamycin Combination Therapy Enhances Anti-Cancer Efficacy
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  129. Sep 2021
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  131. Aug 2021
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    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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  133. Jul 2021
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    EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex
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    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
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    Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
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  139. May 2021
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    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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  142. Apr 2021
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    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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  144. Feb 2021
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    A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-Negative Breast Cancer Anoikis Resistance
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  148. Oct 2020
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    Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B
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    Elevated V-ATPase activity following PTEN loss is required for enhanced oncogenic signaling in breast cancer
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  152. Sep 2020
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    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
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    ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers
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  159. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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  161. Jan 2020
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    Regulation of EZH2 by SMYD2-Mediated Lysine Methylation Is Implicated in Tumorigenesis
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    VISAGE Reveals a Targetable Mitotic Spindle Vulnerability in Cancer Cells
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    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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  166. Nov 2018
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    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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  169. www.sciencedirect.com www.sciencedirect.com
    Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
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    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
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  172. Nov 2017
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    GLUL Promotes Cell Proliferation in Breast Cancer
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