45 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A targetable FTO/SLC7A11/CBS/CTH axis controls cysteine metabolism, growth and survival in NSCLC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13330832/
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13072665/
  5. aacrjournals.org aacrjournals.org
    DS-3939a: A TA-MUC1-directed Antibody-Drug Conjugate with Broad Anti-Tumor Activity
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    aacrjournals.org/mct/article/25/1/7/771286/DS-3939a-A-TA-MUC1-Directed-Antibody-Drug
  6. Mar 2026
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    UFMylation-dependent inhibition of AKT signaling by PHLDA3 in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124726002329
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950896/
  9. Sep 2025
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    YWHAG mediated epithelial-mesenchymal transition facilitates tumor progression and metastatic spread in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0898656825005546
  11. Jul 2025
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70096
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    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002612
  14. Jun 2025
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    The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein
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    link.springer.com/article/10.1007/s00018-025-05763-0
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cathepsin C correlates with M2 macrophage infiltration and regulates the tumor growth and metastasis in non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12139067/
  17. Apr 2025
  18. www.sciencedirect.com www.sciencedirect.com
    ADH1B regulates tumor stemness by activating the cAMP/PKA/CREB1 signaling axis to inhibit recurrence and metastasis of lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S0006291X2500395X
  19. Feb 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11821485/
  21. Dec 2024
  22. www.sciencedirect.com www.sciencedirect.com
    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124724013779
  23. Aug 2024
  24. www.mdpi.com www.mdpi.com
    A New Renieramycin T Right-Half Analog as a Small Molecule Degrader of STAT3
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    mdpi.com/1660-3397/22/8/370
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11321020/
  26. Jul 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Incense-burning smoke ingredient Auramine enhances lincRNA-p21 expression for chemosensitization in p53-mutated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0304389424016844
  28. May 2024
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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    sciencedirect.com/science/article/pii/S1097276524003241
  30. Apr 2024
  31. aacrjournals.org aacrjournals.org
    The immune suppressor IGSF1 as a potential target for cancer immunotherapy
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    aacrjournals.org/cancerimmunolres/article/12/4/491/741941/The-Immune-Suppressor-IGSF1-as-a-Potential-Target
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    The role of RASA2 in predicting radioresistance in lung cancer through regulation of p53
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    ncbi.nlm.nih.gov/pmc/articles/PMC11002505/
  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    DRD1 suppresses cell proliferation and reduces EGFR activation and PD-L1 expression in NSCLC
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13608
  34. Mar 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  36. Feb 2024
  37. aacrjournals.org aacrjournals.org
    First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors
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    aacrjournals.org/clincancerres/article/30/3/506/733551/First-in-Human-Study-with-Preclinical-Data-of-BCL
  38. Jan 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simplified Synthesis of Renieramycin T Derivatives to Target Cancer Stem Cells via β-Catenin Proteasomal Degradation in Human Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10744608/
  40. Nov 2023
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  42. Oct 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Ascorbate Elicits Anti-Cancer Activities against Non-Small Cell Lung Cancer through Hydrogen-Peroxide-Induced-DNA-Damage
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    ncbi.nlm.nih.gov/pmc/articles/PMC10525775/
  44. Sep 2023
  45. www.mdpi.com www.mdpi.com
    Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
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    mdpi.com/2076-3921/10/4/534/htm
  46. Jun 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TL-532, a novel specific Toll-like receptor 3 agonist rationally designed for targeting cancers: discovery process and biological characterization
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236204/
  48. Jan 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
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    ncbi.nlm.nih.gov/pmc/articles/PMC9377749/
  50. Nov 2022
  51. www.researchsquare.com www.researchsquare.com
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  52. Apr 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycosylated Cathepsin V Serves as a Prognostic Marker in Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9043764/
  54. www.sciencedirect.com www.sciencedirect.com
    Tissue remodeling by an opportunistic pathogen triggers allergic inflammation
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    sciencedirect.com/science/article/pii/S1074761322001728
  55. Nov 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy
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    sciencedirect.com/science/article/pii/S2666379121003177
  57. Oct 2021
  58. www.sciencedirect.com www.sciencedirect.com
    MAPK pathway activation selectively inhibits ASCL1-driven small cell lung cancer
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    sciencedirect.com/science/article/pii/S2589004221011925
  59. Jun 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy
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    sciencedirect.com/science/article/pii/S1534580721004810
  61. Apr 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
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    sciencedirect.com/science/article/pii/S0092867420308746
  63. www.mdpi.com www.mdpi.com
    Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
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    mdpi.com/2076-3921/10/4/534/htm
  64. Feb 2021
  65. www.sciencedirect.com www.sciencedirect.com
    CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition
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    sciencedirect.com/science/article/pii/S2211124721000814
  66. Dec 2020
  67. www.sciencedirect.com www.sciencedirect.com
    Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer
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    sciencedirect.com/science/article/pii/S2211124720314339
  68. Oct 2020
  69. mcr.aacrjournals.org mcr.aacrjournals.org
    NRF2-Driven KEAP1 Transcription in Human Lung Cancer
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    mcr.aacrjournals.org/content/18/10/1465
  70. Sep 2020
  71. www.mdpi.com www.mdpi.com
    Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells
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    mdpi.com/2072-6694/12/4/875
  72. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
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    elifesciences.org/articles/53367
  73. Jan 2020
  74. www.sciencedirect.com www.sciencedirect.com
    GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway
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    sciencedirect.com/science/article/pii/S0014482719306949
  75. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
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    sciencedirect.com/science/article/pii/S1534580719305829
  76. Nov 2018
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LOSS OF RUNX1 IS ASSOCIATED WITH AGGRESSIVE LUNG ADENOCARCINOMAS
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    onlinelibrary.wiley.com/doi/10.1002/jcp.26201/full
  78. Nov 2017
  79. www.sciencedirect.com www.sciencedirect.com
    O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate
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    sciencedirect.com/science/article/pii/S1535610817300624