65 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13238812/
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    Intratumoral bicarbonate functions as an adjuvant to potentiate PD-1 blockade in hepatocellular carcinoma
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    nature.com/articles/s41388-026-03836-3
  4. Jun 2026
  5. www.sciencedirect.com www.sciencedirect.com
    Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory
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    sciencedirect.com/science/article/pii/S2666379126002569
  6. May 2026
  7. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Synthesis of 2-Aryl(alkyl)benzimidazole Hydroxamic Acids as HDAC Inhibitors with Anti-Angiogenesis Properties
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202500984
  8. Mar 2026
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    Spatial multi-omics identifies a NOTCH3-mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/imt2.70117
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    EP300 promotes hepatocellular carcinoma proliferation, migration and in vivo tumorigenicity revealed by integrated experimental and bioinformatic analyses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12964607/
  11. Feb 2026
  12. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    TGFβ1 Activates Lnc-APUE to Promote Tumor Metastasis via the Alu Element-Driven STAU1-Mediated Decay of CDH1 mRNA
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518731
  13. Jan 2026
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    Epithelial–Mesenchymal Transition and Stress Adaptations Underlie Yttrium-90 Resistance in Liver Cancer Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC12824473/
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    Guaianolide dimer KGA-1002 targets GRP94 and triggers unfolded protein response-associated degradation of SKP2/AKT axis as a novel antihepatoma agent
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    sciencedirect.com/science/article/pii/S209012322600010X
  16. Dec 2025
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    Post-translational switch of DHCR24 acetylation sustains sterol synthesis and promotes HCC via the 7-ketocholesterol/p62 axis
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  19. Oct 2025
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    Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004225019790
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    B7-H3-mediated reversal of CAR-T cell exhaustion induces a notable antitumour response in ovarian cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12539249/
  22. Aug 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screening reveals that RNA helicase DDX41 triggers ribosome biogenesis and cancer progression through R-loop-mediated RPL/RPS transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12340132/
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    Imaging and targeting S1PR1 in HER2+ tumors
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    sciencedirect.com/science/article/pii/S0969805125000666
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    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322234/
  26. Jun 2025
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    Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S2451945625001655
  28. May 2025
  29. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Antitumor Cytotoxic Activity Retained in Tolerized T Cells Following Daily Dose Escalation of a T-Cell Engager in Cynomolgus Monkeys to Mitigate Cytokine Release Syndrome
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.4812
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    A guide to selecting high-performing antibodies for S1PR1 (UniProt ID: P21453) for use in western blot, immunoprecipitation, and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12022542/
  31. Feb 2025
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    CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors
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  33. aacrjournals.org aacrjournals.org
    Targeting Tumor-Associated Sialic Acids using Chimeric Switch Receptors based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
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    Machine learning-based integration reveals immunological heterogeneity and the clinical potential of T cell receptor (TCR) gene pattern in hepatocellular carcinoma
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    link.springer.com/article/10.1007/s10495-025-02080-6
  35. Jan 2025
  36. www.nature.com www.nature.com
    Re-evaluation of the relationship between PrPc expression and patient prognosis in primary esophageal squamous cell carcinoma and primary hepatocellular carcinoma
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    nature.com/articles/s41598-024-82398-4
  37. 52.53.155.43 52.53.155.43
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  38. Dec 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Global versus local matrix remodeling drives rotational versus invasive collective migration of epithelial cells
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  40. Nov 2024
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11575172/
  42. Sep 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Invention of circRNA promoting RNA to specifically promote circRNA production
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  44. Aug 2024
  45. www.sciencedirect.com www.sciencedirect.com
    YTHDF3-mediated m6A modification of NKD1 regulates hepatocellular carcinoma invasion and metastasis by activating the WNT/β-catenin signaling axis
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  46. May 2024
  47. 52.53.155.43 52.53.155.43
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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  48. Apr 2024
  49. aacrjournals.org aacrjournals.org
    The tautomerase activity of tumor exosomal MIF promotes pancreatic cancer progression by modulating MDSC differentiation
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    Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy
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    sciencedirect.com/science/article/pii/S2352396424001348
  51. Mar 2024
  52. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
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    IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment
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  54. Feb 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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    Diverse temporal and spatial mechanisms work, partially through Stanniocalcin-1, V-ATPase and senescence, to activate the extracellular ATP-mediated drug resistance in human cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10876858/
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    S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway
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    sciencedirect.com/science/article/pii/S0304383524001022
  58. Nov 2023
  59. www.nature.com www.nature.com
    Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway
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    nature.com/articles/s41389-023-00494-y
  60. Sep 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10477178/
  62. Aug 2023
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10422835/
  64. Jul 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    sciencedirect.com/science/article/pii/S2211124723008239
  66. Jun 2023
  67. link.springer.com link.springer.com
    PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition
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    link.springer.com/article/10.1007/s13577-023-00935-1
  68. Jan 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9359749/
  70. Nov 2022
  71. www.sciencedirect.com www.sciencedirect.com
    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    sciencedirect.com/science/article/pii/S2211124722015650
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    circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722015819
  73. Apr 2022
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    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
  75. Mar 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8893721/
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    Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus
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    sciencedirect.com/science/article/pii/S2352396422000871
  78. Feb 2022
  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33929
  80. Aug 2021
  81. 52.53.155.43 52.53.155.43
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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    Untitled document
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    sciencedirect.com/science/article/pii/S0092867418315034
  84. Jul 2021
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC5654054/
  86. May 2021
  87. www.sciencedirect.com www.sciencedirect.com
    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability
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    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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  89. Apr 2021
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    Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
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    sciencedirect.com/science/article/pii/S2405471220302490
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    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
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    DNAJC5 promotes hepatocellular carcinoma cells proliferation though regulating SKP2 mediated p27 degradation
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  93. Dec 2020
  94. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Evidence for liver and peripheral immune cells secreting tumor-suppressive extracellular vesicles in melanoma patients
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  95. Oct 2020
  96. elifesciences.org elifesciences.org
    A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer
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    elifesciences.org/articles/56749
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    Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/full/10.1002/cac2.12103
  98. Sep 2020
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC7249043/
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    UBC12‐mediated SREBP‐1 neddylation worsens metastatic tumor prognosis
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33113
  101. Nov 2018
  102. www.sciencedirect.com www.sciencedirect.com
    N6-Methyladenine DNA Modification in the Human Genome
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    sciencedirect.com/science/article/pii/S109727651830460X
  103. europepmc.org europepmc.org
    Increasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals.
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