70 Matching Annotations
  1. Last 7 days
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    A trifluoromethyl quinazoline inhibits hepatocellular carcinoma proliferation through HDAC1 binding and multi-target mechanisms
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    sciencedirect.com/science/article/pii/S2589004226024156
  3. Jul 2026
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    Single- and dual-target CAR-T cells targeting HBsAg and GPC3 to balance safety and antitumor efficacy in HBV-positive hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004226022224
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    UFMylation Suppresses Hepatocellular Carcinoma Metastasis by Inhibiting β-catenin-Driven Hybrid EMT and NK Cell Evasion
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    aacrjournals.org/cancerres/article/86/13/3213/786139/UFMylation-Suppresses-Hepatocellular-Carcinoma
  6. aacrjournals.org aacrjournals.org
    The tRNA-Derived Fragment tRF-E Promotes Ferroptosis in Hepatocellular Carcinoma to Suppress Tumor Progression
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    aacrjournals.org/cancerres/article/86/13/3233/786155/The-tRNA-Derived-Fragment-tRF-E-Promotes
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An SLCO2B1 mRNA Isoform Acts as a Noncoding RNA to Drive Cancer Progression by Triggering Protein Biosynthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13324349/
  8. Jun 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13238812/
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    Intratumoral bicarbonate functions as an adjuvant to potentiate PD-1 blockade in hepatocellular carcinoma
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    nature.com/articles/s41388-026-03836-3
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    Salmonella vector creates de novo parvovirus that reduces solid tumors and forms antitumor immune memory
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    sciencedirect.com/science/article/pii/S2666379126002569
  12. May 2026
  13. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Synthesis of 2-Aryl(alkyl)benzimidazole Hydroxamic Acids as HDAC Inhibitors with Anti-Angiogenesis Properties
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    chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202500984
  14. Mar 2026
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    Spatial multi-omics identifies a NOTCH3-mediated capillary–mCAF crosstalk driving immune exclusion in hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/imt2.70117
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EP300 promotes hepatocellular carcinoma proliferation, migration and in vivo tumorigenicity revealed by integrated experimental and bioinformatic analyses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12964607/
  17. Feb 2026
  18. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    TGFβ1 Activates Lnc-APUE to Promote Tumor Metastasis via the Alu Element-Driven STAU1-Mediated Decay of CDH1 mRNA
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202518731
  19. Jan 2026
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epithelial–Mesenchymal Transition and Stress Adaptations Underlie Yttrium-90 Resistance in Liver Cancer Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC12824473/
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    Guaianolide dimer KGA-1002 targets GRP94 and triggers unfolded protein response-associated degradation of SKP2/AKT axis as a novel antihepatoma agent
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    sciencedirect.com/science/article/pii/S209012322600010X
  22. Dec 2025
  23. 54.241.53.176 54.241.53.176
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    Post-translational switch of DHCR24 acetylation sustains sterol synthesis and promotes HCC via the 7-ketocholesterol/p62 axis
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    sciencedirect.com:5037/science/article/pii/S2211124725014123
  25. Oct 2025
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    Development of the FGFR4-ADC bearing the ferroptosis inducer sulfasalazine for hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004225019790
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    B7-H3-mediated reversal of CAR-T cell exhaustion induces a notable antitumour response in ovarian cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12539249/
  28. Aug 2025
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR screening reveals that RNA helicase DDX41 triggers ribosome biogenesis and cancer progression through R-loop-mediated RPL/RPS transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC12340132/
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    Imaging and targeting S1PR1 in HER2+ tumors
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    sciencedirect.com/science/article/pii/S0969805125000666
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322234/
  32. Jun 2025
  33. www.sciencedirect.com www.sciencedirect.com
    Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S2451945625001655
  34. May 2025
  35. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Antitumor Cytotoxic Activity Retained in Tolerized T Cells Following Daily Dose Escalation of a T-Cell Engager in Cynomolgus Monkeys to Mitigate Cytokine Release Syndrome
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jat.4812
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A guide to selecting high-performing antibodies for S1PR1 (UniProt ID: P21453) for use in western blot, immunoprecipitation, and immunofluorescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12022542/
  37. Feb 2025
  38. www.sciencedirect.com www.sciencedirect.com
    CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors
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    sciencedirect.com/science/article/pii/S2666379125000382
  39. aacrjournals.org aacrjournals.org
    Targeting Tumor-Associated Sialic Acids using Chimeric Switch Receptors based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells
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    aacrjournals.org/cancerimmunolres/article/12/10/1380/748721/Targeting-Tumor-Associated-Sialic-Acids-Using
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    Machine learning-based integration reveals immunological heterogeneity and the clinical potential of T cell receptor (TCR) gene pattern in hepatocellular carcinoma
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    link.springer.com/article/10.1007/s10495-025-02080-6
  41. Jan 2025
  42. www.nature.com www.nature.com
    Re-evaluation of the relationship between PrPc expression and patient prognosis in primary esophageal squamous cell carcinoma and primary hepatocellular carcinoma
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    nature.com/articles/s41598-024-82398-4
  43. 52.53.155.43 52.53.155.43
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  44. Dec 2024
  45. www.sciencedirect.com www.sciencedirect.com
    Global versus local matrix remodeling drives rotational versus invasive collective migration of epithelial cells
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  46. Nov 2024
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11575172/
  48. Sep 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Invention of circRNA promoting RNA to specifically promote circRNA production
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  50. Aug 2024
  51. www.sciencedirect.com www.sciencedirect.com
    YTHDF3-mediated m6A modification of NKD1 regulates hepatocellular carcinoma invasion and metastasis by activating the WNT/β-catenin signaling axis
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    sciencedirect.com/science/article/pii/S0014482724002830
  52. May 2024
  53. 52.53.155.43 52.53.155.43
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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  54. Apr 2024
  55. aacrjournals.org aacrjournals.org
    The tautomerase activity of tumor exosomal MIF promotes pancreatic cancer progression by modulating MDSC differentiation
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    aacrjournals.org/cancerimmunolres/article/12/1/72/731979/The-Tautomerase-Activity-of-Tumor-Exosomal-MIF
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    Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy
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    sciencedirect.com/science/article/pii/S2352396424001348
  57. Mar 2024
  58. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
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    IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment
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    sciencedirect.com/science/article/pii/S2211124724001633
  60. Feb 2024
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diverse temporal and spatial mechanisms work, partially through Stanniocalcin-1, V-ATPase and senescence, to activate the extracellular ATP-mediated drug resistance in human cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10876858/
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    S100A6 drives lymphatic metastasis of liver cancer via activation of the RAGE/NF-kB/VEGF-D pathway
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    sciencedirect.com/science/article/pii/S0304383524001022
  64. Nov 2023
  65. www.nature.com www.nature.com
    Decreased B4GALT1 promotes hepatocellular carcinoma cell invasiveness by regulating the laminin-integrin pathway
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    nature.com/articles/s41389-023-00494-y
  66. Sep 2023
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10477178/
  68. Aug 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC10422835/
  70. Jul 2023
  71. www.sciencedirect.com www.sciencedirect.com
    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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  72. Jun 2023
  73. link.springer.com link.springer.com
    PSMD4 drives progression of hepatocellular carcinoma via Akt/COX2 pathway and p53 inhibition
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    link.springer.com/article/10.1007/s13577-023-00935-1
  74. Jan 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9359749/
  76. Nov 2022
  77. www.sciencedirect.com www.sciencedirect.com
    Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression
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    sciencedirect.com/science/article/pii/S2211124722015650
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    circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722015819
  79. Apr 2022
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    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
  81. Mar 2022
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8893721/
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    Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus
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    sciencedirect.com/science/article/pii/S2352396422000871
  84. Feb 2022
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα inhibits mesenchymal and amoeboidal movement of liver cancer cell via Gα12
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33929
  86. Aug 2021
  87. 52.53.155.43 52.53.155.43
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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    Untitled document
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    sciencedirect.com/science/article/pii/S0092867418315034
  90. Jul 2021
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sporadic PCDH18 somatic mutations in EpCAM-positive hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC5654054/
  92. May 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Centrosomal Localization of RXRα Promotes PLK1 Activation and Mitotic Progression and Constitutes a Tumor Vulnerability
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    sciencedirect.com/science/article/pii/S1534580720308881
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    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis
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    sciencedirect.com/science/article/pii/S1550413121001108
  95. Apr 2021
  96. www.sciencedirect.com www.sciencedirect.com
    Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
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    sciencedirect.com/science/article/pii/S2405471220302490
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    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
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    DNAJC5 promotes hepatocellular carcinoma cells proliferation though regulating SKP2 mediated p27 degradation
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    sciencedirect.com/science/article/pii/S0167488921000483
  99. Dec 2020
  100. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Evidence for liver and peripheral immune cells secreting tumor-suppressive extracellular vesicles in melanoma patients
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    pubmed.ncbi.nlm.nih.gov/33242827/
  101. Oct 2020
  102. elifesciences.org elifesciences.org
    A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer
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    elifesciences.org/articles/56749
  103. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Increased dopamine and its receptor dopamine receptor D1 promote tumor growth in human hepatocellular carcinoma
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    onlinelibrary.wiley.com/doi/full/10.1002/cac2.12103
  104. Sep 2020
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    APN-mediated phosphorylation of BCKDK promotes hepatocellular carcinoma metastasis and proliferation via the ERK signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC7249043/
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    UBC12‐mediated SREBP‐1 neddylation worsens metastatic tumor prognosis
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33113
  107. Nov 2018
  108. www.sciencedirect.com www.sciencedirect.com
    N6-Methyladenine DNA Modification in the Human Genome
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  109. europepmc.org europepmc.org
    Increasing AR by HIF-2α inhibitor (PT-2385) overcomes the side-effects of sorafenib by suppressing hepatocellular carcinoma invasion via alteration of pSTAT3, pAKT and pERK signals.
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