221 Matching Annotations
  1. Aug 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Engineering affinity-matured variants of an anti-polysialic acid monoclonal antibody with superior cytotoxicity-mediating potency
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    sciencedirect.com/science/article/pii/S2451945625002302
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    TCF25 serves as a nutrient sensor to orchestrate metabolic adaptation and cell death by enhancing lysosomal acidification under glucose starvation
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    sciencedirect.com/science/article/pii/S221112472500957X
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    Differential regulation of FADS2 by EZH2 reveals a metabolic vulnerability in ovarian cancer treatment
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    sciencedirect.com/science/article/pii/S2352396425003238
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    Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells
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    sciencedirect.com/science/article/pii/S2666634025002314
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preadipocyte-induced upregulation of IGFBP5 enhances ovarian cancer tumorigenesis via CREB signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12304763/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322234/
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70142
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70089
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    SLC4A11 is a targetable marker correlated with therapeutic responses in ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309138/
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    Altered fatty acid oxidation via CPT1A promotes epithelial-to-mesenchymal transition in ovarian cancer
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70193
  13. Jul 2025
  14. 52.53.155.43 52.53.155.43
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  15. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Mortalin and PINK1/Parkin-Mediated Mitophagy Represent Ovarian Cancer-Selective Targets for Drug Development
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202505592
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    KLF5-regulated ZDHHC8 reduces chemosensitivity in high-grade serous ovarian cancer through β-catenin signaling
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    nature.com/articles/s41598-025-11845-7
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preadipocyte-induced upregulation of IGFBP5 enhances ovarian cancer tumorigenesis via CREB signaling
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    CD81 Aggravates Ovarian Cancer Progression via p-Cresyl Sulfate-Mediated Mitophagy in Tim4+ Tumour-Associated Macrophages
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    onlinelibrary.wiley.com/doi/10.1111/jcmm.70701
  21. Jun 2025
  22. www.sciencedirect.com www.sciencedirect.com
    Space- and time-defined Monte Carlo dosimetry explains ovarian cancer cell viability in targeted α-particle therapy with [211At]At-PTT
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  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDCA8, targeted by MYBL2, promotes malignant progression and olaparib insensitivity in ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7868764/
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70050
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    The RNA-stability-independent role of the RNA m6A reader YTHDF2 in promoting protein translation to confer tumor chemotherapy resistance
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    Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy
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  29. May 2025
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  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Good manufacturing practice production of an off-the-shelf CD34+ progenitor-derived NK cell product with preserved anti-tumor functionality post-infusion in NOD/SCID/IL2Rgnull mice
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  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bispecific c-Met/PD-1 CAR-T Cells Have Enhanced Therapeutic Effects on Solid Tumor
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    CD38 contributes to tumor progression and tumor microenvironment reshaping in epithelial ovarian cancer
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  35. Apr 2025
  36. www.sciencedirect.com www.sciencedirect.com
    CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
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    The low-dose CHK1 inhibitor prexasertib triggers VDAC1 dephosphorylation to activate mtDNA-STING signaling and synergize immunotherapy
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    sciencedirect.com/science/article/pii/S2211124725003766
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to profile tumor and microenvironment from ovarian cancer patient samples and evaluate cell-based therapy using in vitro killing assays
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    pmc.ncbi.nlm.nih.gov/articles/PMC12002649/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HBO1 determines epithelial-mesenchymal transition and promotes immunotherapy resistance in ovarian cancer cells
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  40. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons
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  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IMGN853 Induces Autophagic Cell Death in Combination Therapy for Ovarian Cancer
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  43. Mar 2025
  44. 52.53.155.43 52.53.155.43
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    Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202410718
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    VIPAS39 confers ferroptosis resistance in epithelial ovarian cancer through exporting ACSL4
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  47. Feb 2025
  48. www.sciencedirect.com www.sciencedirect.com
    Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors
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  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11847841/
  50. www.cell.com www.cell.com
    EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models
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    cell.com/cancer-cell/abstract/S1535-6108(25)00031-5
  51. aacrjournals.org aacrjournals.org
    YAP1 suppression by ZDHHC7 is associated with ferroptosis resistance and poor prognosis in ovarian clear cell carcinoma
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    aacrjournals.org/mct/article/23/11/1652/749309/YAP1-Suppression-by-ZDHHC7-Is-Associated-with
  52. aacrjournals.org aacrjournals.org
    Peptide PDHPS1 inhibits ovarian cancer growth through disrupting YAP signaling
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    aacrjournals.org/mct/article/21/7/1160/705294/Peptide-PDHPS1-Inhibits-Ovarian-Cancer-Growth
  53. link.springer.com link.springer.com
    Comparative analysis and process optimization for manufacturing CAR-T using the PiggyBac system derived from cryopreserved versus fresh PBMCs
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    link.springer.com/article/10.1038/s41598-025-89686-7
  54. ovarianresearch.biomedcentral.com ovarianresearch.biomedcentral.com
    Dynamic and functional analyses of exosomal miRNAs regulating cellular microenvironment of ovarian cancer cells
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    ovarianresearch.biomedcentral.com/articles/10.1186/s13048-025-01608-3
  55. www.sciencedirect.com www.sciencedirect.com
    Exploring the characteristics of immortalized human ovarian surface epithelial cell lines
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    sciencedirect.com/science/article/pii/S2405844025009193
  56. Jan 2025
  57. 52.53.155.43 52.53.155.43
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  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11732399/
  59. www.sciencedirect.com www.sciencedirect.com
    Placental extracellular vesicles induce ovarian tumour cell death in an ex vivo explant model: Possible therapeutic potential
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    sciencedirect.com/science/article/pii/S0143400424008191
  60. Dec 2024
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reduced Levels of miR-145-3p Drive Cell Cycle Progression in Advanced High-Grade Serous Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11592657/
  62. www.sciencedirect.com www.sciencedirect.com
    DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance
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  63. www.sciencedirect.com www.sciencedirect.com
    FOXF1 promotes ovarian cancer metastasis by facilitating HMGA2-mediated USP30-dependent S100A6 deubiquitination
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    sciencedirect.com/science/article/pii/S0925443924006276
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  65. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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  66. Nov 2024
  67. www.sciencedirect.com www.sciencedirect.com
    Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells
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  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multicompartmentalized Microvascularized Tumor-on-a-Chip to Study Tumor-Stroma Interactions and Drug Resistance in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11538101/
  69. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibiting ADAM17 enhances the efficacy of olaparib in ovarian cancer spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11541916/
  70. Oct 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased peritoneal TGF-β1 is associated with ascites-induced NK-cell dysfunction and reduced survival in high-grade epithelial ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11456434/
  72. link.springer.com link.springer.com
    SLC45A4 is involved in malignant progression of ovarian cancer through glycolytic metabolic reprogramming
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    link.springer.com/article/10.1038/s41598-024-74249-z
  73. Sep 2024
  74. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13726
  75. Aug 2024
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anticancer effects of Erzhimaoling decoction in high-grade serous ovarian cancer in vitro and in vivo
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    ncbi.nlm.nih.gov/pmc/articles/PMC11299366/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  78. www.liebertpub.com www.liebertpub.com
    The Microenvironment of Solid Tumors: Components and Current Challenges of Tumor-on-a-Chip Models
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    liebertpub.com/doi/10.1089/ten.teb.2024.0088
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer
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  80. jeccr.biomedcentral.com jeccr.biomedcentral.com
    Chemoresistance is mediated by ovarian cancer leader cells in vitro
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    jeccr.biomedcentral.com/articles/10.1186/s13046-021-02086-3
  81. Jul 2024
  82. ovarianresearch.biomedcentral.com ovarianresearch.biomedcentral.com
    Unveiling G-protein coupled receptors as potential targets for ovarian cancer nanomedicines: from RNA sequencing data analysis to in vitro validation
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    NAMPT-targeting PROTAC and nicotinic acid co-administration elicit safe and robust anti-tumor efficacy in NAPRT-deficient pan-cancers
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  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA-binding protein THUMPD2 inhibits proliferation and promotes metastasis in epithelial ovarian cancer
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  85. www.sciencedirect.com www.sciencedirect.com
    Oncolytic vaccinia virus harboring aphrocallistes vastus lectin exerts anti-tumor effects by directly oncolysis and inducing immune response through enhancing ROS in human ovarian cancer
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    sciencedirect.com/science/article/pii/S0006291X2400891X
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    Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
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    sciencedirect.com/science/article/pii/S0092867424006536
  87. www.nature.com www.nature.com
    ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response
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    nature.com/articles/s42255-024-01060-5
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    Current status of in vitro models for rare gynaecological cancer research
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive analysis of hub genes associated with cisplatin-resistance in ovarian cancer and screening of therapeutic drugs through bioinformatics and experimental validation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11234624/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
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  92. Jun 2024
  93. www.sciencedirect.com www.sciencedirect.com
    Identification and validation of immunity- and disulfidptosis-related genes signature for predicting prognosis in ovarian cancer
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    sciencedirect.com/science/article/pii/S240584402408304X
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional genetic variants of GEN1 predict overall survival of Chinese epithelial ovarian cancer patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC11184878/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of HNRNPA1 induced neoantigen generation via regulating alternative splicing
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    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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  97. www.sciencedirect.com www.sciencedirect.com
    Inhibition of nucleophosmin/B23 sensitizes ovarian cancer cells to immune check-point blockade via PD-L1 in ovarian cancer
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  98. May 2024
  99. 52.53.155.43 52.53.155.43
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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  206. Nov 2021
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  210. Oct 2021
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  215. Aug 2021
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  229. Jun 2021
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  233. May 2021
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  235. Apr 2021
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  238. Mar 2021
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  240. Dec 2020
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  243. Nov 2020
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  245. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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    IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34 +  progenitor-derived NK cells
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  248. Oct 2020
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  251. Sep 2020
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