Hypothesis

22 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pharmacologic Activation of TRPA1 Induces Multi-Target Anticancer Responses via Apoptotic and Mitochondrial Pathways

1
1. scibot 31 Jul 2026
  
  in Public
  
  SW1353
  
  DOI: 10.3390/ph19071080
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13414800/
May 2026
www.sciencedirect.com www.sciencedirect.com

Mitochondrial dysfunction activates ADAMTS-5 expression via mt-dsRNA-PKR-Spi-1 axis in osteoarthritic chondrocytes

1
1. scibot 22 May 2026
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1016/j.isci.2026.115980
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004226013556
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Phase Ib Study of Pembrolizumab in Combination with Intratumoral Injection of Clostridium novyi-NT in Patients with Advanced Solid Tumors

1
1. scibot 20 Sep 2025
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1158/1078-0432.CCR-24-3952
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12434394/
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Dose-dependent multifunctional effects of oxovanadium(IV) thiosemicarbazone complexes: A molecular modeling approach

1
1. scibot 26 Aug 2025
  
  in Public
  
  ATCC, HTB-94
  
  DOI: 10.1016/j.inoche.2025.115371
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1387700325014881
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Exploring adenosine analogs for chondrosarcoma therapy: In vitro and in vivo insights

1
1. scibot 21 Aug 2025
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1016/j.omtn.2025.102642
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12346062/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression

1
1. scibot 14 Aug 2025
  
  in Public
  
  CVCL_0543
  
  DOI: 10.1186/s12967-025-06920-6
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12341233/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Genetic transcriptional regulation profiling of cartilage reveals pathogenesis of osteoarthritis

1
1. scibot 28 Jun 2025
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1016/j.ebiom.2025.105821
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12278629/
www.cell.com www.cell.com

Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming

1
1. scibot 11 Jun 2025
  
  in Public
  
  ATCCHTB-94
  
  DOI: 10.1016/j.cmet.2025.05.009
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Protein Phosphatase 1 Regulatory Subunit 3C integrates cholesterol metabolism and isocitrate dehydrogenase in chondrocytes and neoplasia

1
1. scibot 19 May 2025
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1073/pnas.2501519122
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12037013/
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion

1
1. scibot 04 Oct 2024
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1158/1541-7786.MCR-23-1003
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11445649/
Apr 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities

1
1. scibot 10 Apr 2024
  
  in Public
  
  SW1353
  
  DOI: 10.1002/jbt.23706
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @AniH
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1002/jbt.23706
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis

1
1. scibot 22 Dec 2023
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1016/j.xcrm.2023.101342
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379123005591
Mar 2023
www.sciencedirect.com www.sciencedirect.com

YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522

1
1. scibot 11 Mar 2023
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1016/j.jbo.2023.100474
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2212137423000076
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Analysis of mitochondrial double-stranded RNAs in human cells

1
1. scibot 21 Jan 2023
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1016/j.xpro.2022.102007
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666166722008875
www.mdpi.com www.mdpi.com

MIA/CD-RAP Regulates MMP13 and Is a Potential New Disease-Modifying Target for Osteoarthritis Therapy

1
1. scibot 12 Jan 2023
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.3390/cells12020229
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

mdpi.com/2073-4409/12/2/229
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hsa_circ_0097271 Knockdown Attenuates Osteosarcoma Progression via Regulating miR-640/MCAM Pathway

1
1. scibot 09 Nov 2022
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1155/2022/8084034
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9630489/
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development

1
1. scibot 10 Aug 2022
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1016/j.celrep.2022.111178
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722009913
Jul 2022
link.springer.com link.springer.com

Shikonin derivatives cause apoptosis and cell cycle arrest in human chondrosarcoma cells via death receptors and MAPK regulation

1
1. scibot 13 Jul 2022
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1186/s12885-022-09857-x
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

link.springer.com/article/10.1186/s12885-022-09857-x
Dec 2021
www.nature.com www.nature.com

Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells

1
1. scibot 21 Dec 2021
  
  in Public
  
  RRID:CVCL_0543
  
  DOI: 10.1038/s41598-021-03529-9
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

Annotators

scibot

URL

nature.com/articles/s41598-021-03529-9
Jul 2021
link.springer.com link.springer.com

Expression of Enterocin-P in HEK Platform: Evaluation of Its Cytotoxic Effects on Cancer Cell Lines and Its Potency to Interact with Cell-Surface Glycosaminoglycan by Molecular Modeling

1
1. scibot 29 Jul 2021
  
  in Public
  
  ATCC HTB-94
  
  DOI: 10.1007/s10989-019-09956-7
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543 RRIDCUR:Unrecognized
Visit annotations in context

Tags

RRIDCUR:Unrecognized

RRID:CVCL_0543

Annotators

scibot

URL

link.springer.com/article/10.1007/s10989-019-09956-7
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells

1
1. scibot 27 Jul 2021
  
  in Public
  
  SW1353
  
  DOI: 10.1038/s41598-017-13994-w
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @mpairish
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_0543
Visit annotations in context

Tags

RRID:CVCL_0543

RRIDCUR:Missing

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5647403/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

The immune landscape of chondrosarcoma reveals an immunosuppressive environment and exposes macrophages as a promising therapeutic target

1
1. scibot 10 Sep 2020
  
  in Public
  
  CVCL_0543
  
  DOI: 10.1016/j.jbo.2019.100271
  
  Resource: (BCRJ Cat# 0382, RRID:CVCL_0543)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0543
  
  What is this?
  
  RRID:CVCL_0543 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_0543

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221213741930168X