96 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pharmacologic Activation of TRPA1 Induces Multi-Target Anticancer Responses via Apoptotic and Mitochondrial Pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC13414800/
  3. Jul 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Triphenylphosphonium–triazole hybrids as mitochondria-targeted anticancer agents: design, DNA binding, cytotoxicity study, fluorescent apoptosis imaging and molecular docking
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    pmc.ncbi.nlm.nih.gov/articles/PMC13353900/
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    Genes Associated With Fracture Risk in Thoroughbred Horses Have Novel Roles in Osteogenesis
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    onlinelibrary.wiley.com/doi/10.1002/age.70166
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    DDX3 Regulates the Innate Immune Response to Bone Sarcomas
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    biorxiv.org/content/10.64898/2026.07.01.735844v1
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prognostic characteristics of disulfidptosis-related genes across cancers and their potential implications in osteosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13319833/
  8. Jun 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In Vitro Biological Evaluation of Titanium Implants Anodized With Aqueous Extract of Psidium guajava and Conventional Electrolytes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13238503/
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    Unconventional activation of the proto-oncogene FGFR1 by extracellular phosphate via H2O2-mediated kinase oxidation
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    sciencedirect.com/science/article/pii/S2211124726005826
  11. May 2026
  12. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Combined Inhibition of ATR and Ribonucleotide Reductase Induces Synergistic Antineoplastic Activity in Osteosarcoma Cells
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    onlinelibrary.wiley.com/doi/10.1002/cnr2.70568
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136882/
  14. Apr 2026
  15. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Incorporation of Selenium into Sol–Gel-Derived Bioactive Glass: Influence on Glass Structure, Bioactivity, and its Selective Cytotoxicity
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adem.202502970
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2-COL3A1 axis
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70245
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    1-s2.0-S2589004226011119-main-html.html
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  18. aacrjournals.org aacrjournals.org
    The recycling collagen receptor uPARAP is a unique mediator of stromal drug delivery to carcinoma cells
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    aacrjournals.org/mct/article/25/1/140/771292/The-Recycling-Collagen-Receptor-uPARAP-Is-a-Unique
  19. Mar 2026
  20. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    The ITGB2-COPS3-SOX2 Axis and SOX2 Liquid-Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202520913
  21. Feb 2026
  22. www.sciencedirect.com www.sciencedirect.com
    Modulating Galectin-1 in human osteoblast-like cells alters mineralisation and influences the expression of genes associated with osteoblasts and osteocytes
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    sciencedirect.com/org/science/article/pii/S1573493526000159
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    In vitro modeling of nutritional and mitochondria-targeted therapies for osteosarcoma
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    biorxiv.org/content/10.64898/2026.02.19.706776v1
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    To Dye or Not to Dye: Unraveling the Impact of Surface Chemistry on Cerium Oxide Nanoparticles–Cell Interactions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12908425/
  25. www.nature.com www.nature.com
    Dynamic assessment of a humanized bone tumour microenvironment reveals insights into osteosarcoma primary tumour remodelling and lung metastases
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    nature.com/articles/s41598-025-29941-z
  26. Jan 2026
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct Regulation of the ARF and TAp73 Tumor Suppressor Genes by the Transcription Factor E2F1 Enables Discrimination of Cancer Cells from Normal Growing Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12785935/
  28. Dec 2025
  29. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Structural characterization, DNA binding properties and anticancer activities of new tetrazole compounds
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  30. Nov 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metastasis-Initiating Osteosarcoma Subpopulations Establish Paracrine Interactions with Lung and Tumor Cells to Create a Metastatic Niche
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616249/
  32. Sep 2025
  33. elifesciences.org elifesciences.org
    p53 isoforms have a high aggregation propensity, interact with chaperones and lack binding to p53 interaction partners
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    LAT1-Targeted Alpha Therapy Using 211At-AAMT for Bone and Soft Tissue Sarcomas
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor that Unleashes PD-1 Checkpoint and CAR T-cell Immunotherapies
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  36. Aug 2025
  37. www.sciencedirect.com www.sciencedirect.com
    Dose-dependent multifunctional effects of oxovanadium(IV) thiosemicarbazone complexes: A molecular modeling approach
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  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12341233/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Conserved and unique features of terminal telomeric sequences in ALT-positive cancer cells
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  40. Jul 2025
  41. www.sciencedirect.com www.sciencedirect.com
    TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling
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  42. Jun 2025
  43. www.cell.com www.cell.com
    Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming
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    cell.com/cell-metabolism/abstract/S1550-4131(25)00265-7
  44. May 2025
  45. elifesciences.org elifesciences.org
    Dimeric R25CPTH(1–34) activates the parathyroid hormone-1 receptor in vitro and stimulates bone formation in osteoporotic female mice
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    elifesciences.org/articles/97579
  46. Apr 2025
  47. www.nature.com www.nature.com
    Deciphering UBE4B phosphorylation dynamics: a key mechanism in p53 accumulation and cancer cell response to DNA damage
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    nature.com/articles/s41420-025-02441-9
  48. Mar 2025
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Biological Activity of Biomarkers Associated With Metastasis in Osteosarcoma Cell Lines
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    onlinelibrary.wiley.com/doi/10.1002/cam4.70391
  50. Jan 2025
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Developing a 3D bone model of osteosarcoma to investigate cancer mechanisms and evaluate treatments
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    pmc.ncbi.nlm.nih.gov/articles/PMC11670810/
  52. Dec 2024
  53. jhoonline.biomedcentral.com jhoonline.biomedcentral.com
    Tumor-derived G-CSF induces an immunosuppressive microenvironment in an osteosarcoma model, reducing response to CAR.GD2 T-cells
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    jhoonline.biomedcentral.com/articles/10.1186/s13045-024-01641-7
  54. Sep 2024
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unlocking the Secrets of Adipose Tissue: How an Obesity-Associated Secretome Promotes Osteoblast Dedifferentiation via TGF-β1 Signaling, Paving the Path to an Adipogenic Phenotype
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    ncbi.nlm.nih.gov/pmc/articles/PMC11394205/
  56. Aug 2024
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC9977765/
  58. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Horie-html.html
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    52.53.155.43/b5e8e877c627d157950951119edc64db79086ad6/Molecular Oncology - 2023 - Horie-html.html
  59. Jun 2024
  60. www.biorxiv.org www.biorxiv.org
    Metastasis-initiating osteosarcoma subpopulations establish paracrine interactions with both lung and tumor cells to create a metastatic niche
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    biorxiv.org/content/10.1101/2024.06.09.597967v1
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    Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
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    sciencedirect.com/science/article/pii/S2211124724006442
  62. May 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT5B drives osteosarcoma stemness, chemoresistance and metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11061378/
  64. Apr 2024
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23706
  66. biologydirect.biomedcentral.com biologydirect.biomedcentral.com
    Circ_0002669 promotes osteosarcoma tumorigenesis through directly binding to MYCBP and sponging miR-889-3p
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    biologydirect.biomedcentral.com/articles/10.1186/s13062-024-00466-1
  67. Mar 2024
  68. www.sciencedirect.com www.sciencedirect.com
    A unique chaperoning mechanism in class A JDPs recognizes and stabilizes mutant p53
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  69. Feb 2024
  70. www.sciencedirect.com www.sciencedirect.com
    Targeting TOP2B as a vulnerability in aging and aging-related diseases
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    sciencedirect.com/science/article/pii/S0925443924000292
  71. Jan 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCDC85A is regulated by miR-224-3p and augments cancer cell resistance to endoplasmic reticulum stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC10391547/
  73. Aug 2023
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effect of Er: YAG Laser Irradiation on Bone Metabolism-Related Factors Using Cultured Human Osteoblasts
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    ncbi.nlm.nih.gov/pmc/articles/PMC10423954/
  75. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/908848ce9212d2a4c8be94b24c71e399d1f50f03/Molecular Oncology - 2023 - Ito-html.html
  76. Jul 2023
  77. www.sciencedirect.com www.sciencedirect.com
    A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma
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    sciencedirect.com/science/article/pii/S1525001623003155
  78. May 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metal-Induced Energy Transfer (MIET) for Live-Cell Imaging with Fluorescent Proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10173696/
  80. Jan 2023
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osteogenic differentiation of encapsulated cells in dexamethasone-loaded phospholipid-induced silk fibroin hydrogels
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    ncbi.nlm.nih.gov/pmc/articles/PMC9840088/
  82. Dec 2022
  83. 52.53.155.43 52.53.155.43
    Relevance of Abnormal KCNN1 Expression and Osmotic Hypersensitivity in Ewing Sarcoma
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    52.53.155.43/159f5160e811f71bef05831a583c90be3594ad4a/cancers-14-04819-html.html
  84. Nov 2022
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hsa_circ_0097271 Knockdown Attenuates Osteosarcoma Progression via Regulating miR-640/MCAM Pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9630489/
  86. Oct 2022
  87. www.sciencedirect.com www.sciencedirect.com
    Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization
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    sciencedirect.com/science/article/pii/S2451945622003506
  88. Aug 2022
  89. www.sciencedirect.com www.sciencedirect.com
    Discovery of compounds that reactivate p53 mutants in vitro and in vivo
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    sciencedirect.com/science/article/pii/S2451945622002756
  90. Jul 2022
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    Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
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    sciencedirect.com/science/article/pii/S2211124722008798
  92. Jun 2022
  93. www.sciencedirect.com www.sciencedirect.com
    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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    sciencedirect.com/science/article/pii/S2589004222007520
  94. Apr 2022
  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lung fibrosis is a novel therapeutic target to suppress lung metastasis of osteosarcoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34008
  96. www.sciencedirect.com www.sciencedirect.com
    Repurposing antiparasitic antimonials to noncovalently rescue temperature-sensitive p53 mutations
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    sciencedirect.com/science/article/pii/S2211124722003709
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    MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells
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    sciencedirect.com/science/article/pii/S2211124722003503
  98. Mar 2022
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local treatment of a pediatric osteosarcoma model with a 4-1BBL armed oncolytic adenovirus results in an antitumor effect and leads to immune memory
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    ncbi.nlm.nih.gov/pmc/articles/PMC7612474/
  100. Feb 2022
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8845119/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal stem cell-derived exosomes carrying microRNA-150 suppresses the proliferation and migration of osteosarcoma cells via targeting IGF2BP1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8798822/
  103. Nov 2021
  104. mct.aacrjournals.org mct.aacrjournals.org
    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
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    mct.aacrjournals.org/content/20/11/2151
  105. Aug 2021
  106. www.sciencedirect.com www.sciencedirect.com
    Innate immune response orchestrates phosphoribosyl pyrophosphate synthetases to support DNA repair
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    sciencedirect.com/science/article/pii/S1550413121003259
  107. Jul 2021
  108. elifesciences.org elifesciences.org
    KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia
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    elifesciences.org/articles/57436
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    The immune landscape of chondrosarcoma reveals an immunosuppressive environment and exposes macrophages as a promising therapeutic target
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    sciencedirect.com/science/article/pii/S221213741930168X
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGF-β signalling and PEG10 are mutually exclusive and inhibitory in chondrosarcoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC5647403/
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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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    sciencedirect.com/science/article/pii/S1097276521004974
  112. May 2021
  113. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    sciencedirect.com/science/article/pii/S0092867421004955
  114. Apr 2021
  115. www.sciencedirect.com www.sciencedirect.com
    Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
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  116. Feb 2021
  117. www.sciencedirect.com www.sciencedirect.com
    A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia
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    sciencedirect.com/science/article/pii/S1097276520308406
  118. Jan 2021
  119. www.sciencedirect.com www.sciencedirect.com
    Metabolic compensation activates pro-survival mTORC1 signaling upon 3-phosphoglycerate dehydrogenase inhibition in osteosarcoma
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    sciencedirect.com/science/article/pii/S2211124720316673
  120. Dec 2020
  121. link.springer.com link.springer.com
    GD2 or HER2 targeting T cell engaging bispecific antibodies to treat osteosarcoma
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    link.springer.com/article/10.1186/s13045-020-01012-y
  122. Nov 2020
  123. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
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    pubmed.ncbi.nlm.nih.gov/33147457/
  124. Oct 2020
  125. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TRPV4 activity regulates nuclear Ca2+ and transcriptional functions of β‐catenin in a renal epithelial cell model
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    onlinelibrary.wiley.com/doi/10.1002/jcp.30096
  126. Sep 2020
  127. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Phosphorylation‐dependent osterix degradation negatively regulates osteoblast differentiation
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    faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202001340R
  128. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Histone deacetylase inhibition prevents the growth of primary and metastatic osteosarcoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33046
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient‐derived osteosarcoma cells and synergizes with cisplatin and talazoparib
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    ncbi.nlm.nih.gov/pmc/articles/PMC7384073/
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Positron Emission Tomography Detects In Vivo Expression of Disialoganglioside GD2 in Mouse Models of Primary and Metastatic Osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC6571039/
  131. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The endoplasmic reticulum acetyltransferases ATase1/NAT8B and ATase2/NAT8 are differentially regulated to adjust engagement of the secretory pathway
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14958
  132. Aug 2020
  133. link.springer.com link.springer.com
    Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
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    link.springer.com/article/10.1186/s12885-019-6499-y
  134. Jan 2020
  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mycophenolic Acid is a Drug with the Potential to be Repurposed for Suppressing Tumour Growth and Metastasis in Osteosarcoma Treatment
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32735
  136. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Expression of the double‐stranded RNA‐dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion
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    onlinelibrary.wiley.com/doi/abs/10.1002/jcp.29024
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autocrine production of reproductive axis neuropeptides affects proliferation of canine osteosarcoma in vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC6379937/
  138. Apr 2019
  139. elifesciences.org elifesciences.org
    Palmitoylated SCP1 is targeted to the plasma membrane and negatively regulates angiogenesis
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    elifesciences.org/content/6/e22058
  140. Nov 2018
  141. www.sciencedirect.com www.sciencedirect.com
    Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain
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    sciencedirect.com/science/article/pii/S0969212618301771
  142. www.sciencedirect.com www.sciencedirect.com
    Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses
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    sciencedirect.com/science/article/pii/S1535610818303180
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  144. europepmc.org europepmc.org
    Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells.
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  145. Nov 2017
  146. www.nature.com www.nature.com
    Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism
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  147. www.sciencedirect.com www.sciencedirect.com
    Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
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    sciencedirect.com/science/article/pii/S2451945617300636
  148. onlinelibrary.wiley.com onlinelibrary.wiley.com
    S100B + A1 CELISA: A Novel Potency Assay and Screening Tool for Redifferentiation Stimuli of Human Articular Chondrocytes
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    onlinelibrary.wiley.com/doi/10.1002/jcp.25682/full
  149. www.sciencedirect.com www.sciencedirect.com
    Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor
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    sciencedirect.com/science/article/pii/S0092867416313083