100 Matching Annotations
  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    SDP-LIV1, a Novel and Optimized LIV-1 Antibody-drug Conjugate Demonstrating Superior Anti-Tumor Efficacy and Favorable Safety Profile for Treatment of Solid Tumors
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    aacrjournals.org/mct/article/25/2/322/771935/SDP-LIV1-a-Novel-and-Optimized-LIV-1-Antibody-Drug
  3. Mar 2026
  4. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70330
  5. Feb 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Label‐free imaging of intracellular structures in living mammalian cells via external apodization phase‐contrast microscopy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12914761/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defective DNA Damage Response is a Targetable Therapeutic Vulnerability in ESR1 Mutant Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12898867/
  8. Jan 2026
  9. www.sciencedirect.com www.sciencedirect.com
    Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers
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    sciencedirect.com/science/article/pii/S2666379125006500
  10. Dec 2025
  11. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    SNCA inhibits breast cancer progression through TP53AIP1–p53-mediated mitochondrial apoptosis and suppression of cancer stemness
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    sciencedirect.com:5037/science/article/pii/S2352304225004878
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    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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    sciencedirect.com:5037/science/article/pii/S2666379125005518
  13. Nov 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trastuzumab Deruxtecan (T-DXd) Resistance via Loss of HER2 Expression and Binding
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    pmc.ncbi.nlm.nih.gov/articles/PMC12631751/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sequestration and suppressed synthesis of oncogenic HMGA1 using engineered adenoviruses decreases human pancreatic and breast cancer cell characteristics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582467/
  16. Oct 2025
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    YEATS4 reads histone crotonylation to promote fatty acid metabolism and cancer cell stemness
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    sciencedirect.com/science/article/pii/S2211124725011714
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bone-Induced Her2 Promotes Secondary Metastasis in HR+/Her2− Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964846/
  19. Aug 2025
  20. www.sciencedirect.com www.sciencedirect.com
    Building simplified cancer subtyping and prediction models with glycan gene signatures
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    sciencedirect.com/science/article/pii/S2667237525001766
  21. Jul 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Curcumin Induces Homologous Recombination Deficiency by BRCA2 Degradation in Breast Cancer and Normal Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12248657/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint Therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214883/
  24. May 2025
  25. link.springer.com link.springer.com
    Microtubule associated serine/threonine kinase-3 inhibits the malignant phenotype of breast cancer by promoting phosphorylation-mediated ubiquitination degradation of yes-associated protein
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    link.springer.com/article/10.1186/s13058-025-02028-3
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11091964/
  27. Apr 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-invasive multi-cancer detection using DNA hypomethylation of LINE-1 retrotransposons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11959274/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sulfatase 2 inhibition sensitizes triple-negative breast cancer cells to paclitaxel through augmentation of extracellular ATP
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    pmc.ncbi.nlm.nih.gov/articles/PMC11951697/
  30. Mar 2025
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    Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death
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    sciencedirect.com/science/article/pii/S1534580725001170
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    CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety
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    sciencedirect.com/science/article/pii/S1535610825000583
  33. Feb 2025
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RET inhibition overcomes resistance to combined CDK4/6 inhibitor and endocrine therapy in ER+ breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11808005/
  35. Jan 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Patient-derived response estimates from zero-passage organoids of luminal breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11687200/
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    Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk
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    sciencedirect.com/science/article/pii/S2666379124006517
  38. Dec 2024
  39. 52.53.155.43 52.53.155.43
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  40. Nov 2024
  41. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    biorxiv.org/content/10.1101/2024.11.07.622456v1
  42. Sep 2024
  43. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Dynamic methylation and expression of alternative promoters for oestrogen receptor alpha in cell line models of fulvestrant resistance
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13713
  44. Aug 2024
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    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
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    Adipocytes promote metastasis of breast cancer by attenuating the FOXO1 effects and regulating copper homeostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320833/
  47. aacrjournals.org aacrjournals.org
    Nanoparticle-based combination therapy enhances fulvestrant efficacy and overcomes tumor resistance in ER-positive breast cancer
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    aacrjournals.org/cancerres/article/83/17/2924/728581/Nanoparticle-Based-Combination-Therapy-Enhances
  48. Jul 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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    Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
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    sciencedirect.com/science/article/pii/S0092867424006524
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    Affimer reagents enable targeted delivery of therapeutic agents and RNA via Virus-Like Particles
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    sciencedirect.com/science/article/pii/S2589004224016869
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  53. www.mdpi.com www.mdpi.com
    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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    mdpi.com/1422-0067/25/13/7475
  54. May 2024
  55. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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    nature.com/articles/s41416-024-02697-5
  56. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063767/
  59. Mar 2024
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and characterization of a small molecule Bcl-2 Functional Converter
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    ncbi.nlm.nih.gov/pmc/articles/PMC10911799/
  61. Feb 2024
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-Induced Senescence Contributes to the Efficacy of Abemaciclib in Patients with Dedifferentiated Liposarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870201/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10849765/
  64. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An estrogen-regulated long non-coding RNA NCALD promotes luminal breast cancer proliferation by activating GRHL2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10829383/
  66. Jan 2024
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA
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    ncbi.nlm.nih.gov/pmc/articles/PMC10761696/
  68. Oct 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543960/
  70. Sep 2023
  71. www.sciencedirect.com www.sciencedirect.com
    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
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    sciencedirect.com/science/article/pii/S2211124723011154
  72. Jul 2023
  73. www.sciencedirect.com www.sciencedirect.com
    High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
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    sciencedirect.com/science/article/pii/S221112472300832X
  74. Jun 2023
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ERα/LKB1 complex upregulates E-cadherin expression and stimulates breast cancer growth and progression upon adiponectin exposure
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34626
  76. www.science.org www.science.org
    HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis
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    science.org/doi/10.1126/sciadv.ade1155
  77. May 2023
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10197958/
  79. Mar 2023
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9444924/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sustained oncogenic signaling in the cytostatic state enables targeting of non-proliferating persistent cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9444958/
  82. Oct 2022
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COMPREHENSIVE DRUG RESPONSE PROFILING AND PAN-OMIC ANALYSIS IDENTIFIED THERAPEUTIC CANDIDATES AND PROGNOSTIC BIOMARKERS FOR ASIAN CHOLANGIOCARCINOMA
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    ncbi.nlm.nih.gov/pmc/articles/PMC9563539/
  84. Aug 2022
  85. 52.53.155.43 52.53.155.43
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  86. Apr 2022
  87. www.sciencedirect.com www.sciencedirect.com
    A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway
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    sciencedirect.com/science/article/pii/S258900422200445X
  88. Jan 2022
  89. onlinelibrary.wiley.com onlinelibrary.wiley.com
    mdm2 gene amplification is associated with luminal breast cancer progression in humanized PDX mice and a worse outcome of estrogen receptor positive disease
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33911
  90. Sep 2021
  91. onlinelibrary.wiley.com onlinelibrary.wiley.com
    MLL3 is a de novo cause of endocrine therapy resistance
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    onlinelibrary.wiley.com/doi/10.1002/cam4.4285
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    Oncogene-dependent sloppiness in mRNA translation
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    sciencedirect.com/science/article/pii/S109727652100736X
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
  94. Aug 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6408623/
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    As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
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    sciencedirect.com/science/article/pii/S1550413117307167
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    sciencedirect.com/science/article/pii/S1535610818305270
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    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S2405471219303874
  99. Jul 2021
  100. www.sciencedirect.com www.sciencedirect.com
    Thioglycosides Are Efficient Metabolic Decoys of Glycosylation that Reduce Selectin Dependent Leukocyte Adhesion
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    sciencedirect.com/science/article/pii/S2451945618303325
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    Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719307685
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    KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
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    sciencedirect.com/science/article/pii/S153561081830480X
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calmodulin-like protein 3 is an estrogen receptor alpha coregulator for gene expression and drug response in a SNP, estrogen, and SERM-dependent fashion
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    ncbi.nlm.nih.gov/pmc/articles/PMC5562991/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8238250/
  105. May 2021
  106. www.sciencedirect.com www.sciencedirect.com
    Opposing roles of E3 ligases TRIM23 and TRIM21 in regulation of ion channel ANO1 protein levels
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    sciencedirect.com/science/article/pii/S0021925821005275
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    Deciphering the signaling network of breast cancer improves drug sensitivity prediction
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    sciencedirect.com/science/article/pii/S2405471221001113
  108. Apr 2021
  109. www.sciencedirect.com www.sciencedirect.com
    Efficient inhibition of O-glycan biosynthesis using the hexosamine analog Ac5GalNTGc
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    sciencedirect.com/science/article/pii/S245194562100043X
  110. www.sciencedirect.com www.sciencedirect.com
    The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells
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    sciencedirect.com/science/article/pii/S1534580721002057
  111. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
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    sciencedirect.com/science/article/pii/S1535610820302166
  112. Mar 2021
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IP6K2 predicts favorable clinical outcome of primary breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7976380/
  114. Feb 2021
  115. www.sciencedirect.com www.sciencedirect.com
    TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions
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    sciencedirect.com/science/article/pii/S2211124721000899
  116. Nov 2020
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    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
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    sciencedirect.com/science/article/pii/S2211124720313309
  118. Oct 2020
  119. www.cell.com www.cell.com
    Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
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    cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
  120. Sep 2020
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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    ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
  122. cancerres.aacrjournals.org cancerres.aacrjournals.org
    A Novel Bioengineered MicroRNA-127 Prodrug Suppresses The Growth And Metastatic Potential Of Triple Negative Breast Cancer Cells
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    cancerres.aacrjournals.org/content/80/3/418
  123. academic.oup.com academic.oup.com
    Differential regulation and targeting of estrogen receptor α turnover in invasive lobular breast carcinoma
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    academic.oup.com/endo/article/161/9/bqaa109/5866024
  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FGF13 promotes metastasis of triple‐negative breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32874
  125. www.sciencedirect.com www.sciencedirect.com
    Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor
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  128. Jan 2020
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  136. Nov 2018
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  143. Nov 2017
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