450 Matching Annotations
  1. Last 7 days
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    A truncated TNS3 isoform expressed in metastatic triple negative breast cancer stabilizes FAK and promotes lung metastasis
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    nature.com/articles/s41388-026-03894-7
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    CASM regulates p62/KEAP1/NRF2 antioxidant responses to lysosome damage
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    biorxiv.org/content/10.64898/2026.07.08.736046v1
  4. Jul 2026
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    Oncolytic HSV-1-Mediated JAG1 Blockade Induces Glioma Senescence-Associated Secretory Phenotype to Increase Macrophage Activation and Cetuximab-Mediated Senolysis
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    Immune-associated alternative splicing signatures define molecular subtypes in breast cancer
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    Distinct metabolic dependency on BCAA defines cancer stemness and malignancy in human triple-negative breast cancer
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    Targeting microRNA let-7b-5p-mediated aberrant androgen receptor signaling for prevention of hormone receptor-negative breast cancer
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    Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple-Negative Breast Cancer
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  10. Jun 2026
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    Targeting Steroid-Metabolizing Enzymes with 15β-Substituted Estrone Analogues: Dual Discovery of AKR1C2/17β-HSD1 Inhibitors and a Fluorescent 17β-HSD1 Ligand
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    Genome reorganization and its functional impact during breast cancer progression
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    A Far-Red FRET biosensor for AMPK enables multiplexed imaging of single-cell bioenergetic homeostasis
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    The modulation of AUF1 regulates the R-loop resolution activating the immune response in DDR
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    miR-3648 regulates cell functions and acts as a potential biomarker to predict prognosis in breast cancer and its bioinformatics analysis
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  16. May 2026
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification and validation of a seven-gene metastasis-associated prognostic model in breast cancer
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    Protocol for cell cycle-resolved high-content imaging of transcription condensate dynamics in human cells
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  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual Inhibition of TRIP13 and Aurora A Induces Mitotic DNA Damage and Concurrent Pyroptotic-apoptotic Cell Death in Rb-deficient Cancer Cells
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    Autophagy-lysosomal dependency defines a vulnerable physiological state in drug-tolerant persister cells of triple-negative breast cancer
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    PFDN5 synergizes with anti-PD1 therapy to promote triple-negative breast cancer cell death through JAK2/STAT3/c-Myc signaling axis
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  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HSPA6 Promotes Ferroptosis in Triple-Negative Breast Cancer by Rewiring Lipid Metabolism to Potentiate Membrane Lipid Peroxidation
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  23. Apr 2026
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    Combinatorial inhibition of IGF2BP3-regulated receptor tyrosine kinases offers a new therapeutic strategy for triple-negative breast cancer
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    CircNSD2 promotes metastasis and immune escape by increasing the USP10/SRSF6-mediated alternative splicing of TPM1 in TNBC
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    LINC01929 mediates breast cancer immunosuppression and is an immunotherapy target
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    Integrative Genomic Analysis Identifies MAGT1 as a Key Regulator of Proliferation and Poor Prognosis in Breast Cancer
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    LINC01235 Is an Upstream Regulator of the NFIB Gene and the Notch Pathway in Triple-Negative Breast Cancer
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    Delivery of Pleckstrin-Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
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  32. Mar 2026
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    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    The discovery and characterization of HBS-101, a novel inhibitor of midkine, as a therapeutic agent for the treatment of triple negative breast cancer
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    Inhibition of MCL-1 and MEK overcomes MEK inhibitor resistance in triple-negative and inflammatory breast cancers
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  42. Feb 2026
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    Spermine Oxidase Serves as a Key Functional Node in Microbial Dysbiosis-Induced Breast Carcinogenesis
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    Targeting the SIN1 mediated TTK/LDHA-H3K18la-GLUT3 Axis Disrupts Metabolic-Epigenetic Crosstalk and Suppresses Progression in Hyperglycolytic Breast Cancer
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    Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression
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    Integration of Demethylation-Switchable Deoxyribozyme with Controllable Self-Assembly of Branched DNA Nanostructures Enables In Situ Monitoring of FTO Demethylation in Living Cells
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    Single-Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in Cancers
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    RAD51 succinylation regulates homologous recombination and contributes to the chemosensitivity in cancer
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    IL-6R blockade with tocilizumab disrupts pericyte– and tumor cell–driven IL-6/STAT3 signaling, enhancing docetaxel efficacy in ER+ breast cancer
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    HER2-dependent paraptosis and ferroptosis induction by cannabidiol in breast cancer cells
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  60. Jan 2026
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    Improved flux profiling in genome-scale modeling of human cell metabolism
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    Notch1 regulates Orai1 and Orai3 expression in breast cancer cells
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    Extracellular Matrix Viscoelasticity Regulates Mammary Branching Morphogenesis
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    Gasdermin D Cleavage and Cytokine Release, Indicative of Pyroptotic Cell Death, Induced by Ophiobolin A in Breast Cancer Cell Lines
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  66. Dec 2025
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    EMT-induced stem cell and mesenchymal programs can be decoupled via cell division and ESRP1-dependent mechanisms
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    Dual roles of TRPV2 in the innate immune response to cytosolic DNA: Arresting dormant and boosting activated STING
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    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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    Aberrant hypothalamic neuronal activity blunts glucocorticoid diurnal rhythms in murine breast cancer
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    Self-Regulated Cobalt–Zinc–Ferrite Nanoprobe for Targeted Chemomagnetic Hyperthermia in Cancer Therapy
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    pubs.acs.org/doi/full/10.1021/acsami.5c17309
  72. Nov 2025
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    Cu 3 N–Fe nanocube-based electrochemical sensing of cancer metabolites with minute-scale response time
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    Synergistic Reduction of Breast Cancer Cell Viability and Aggressiveness Through Dual Inhibition of APE1 Redox Function and STAT3 Signaling
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    onlinelibrary.wiley.com/doi/10.1002/cbin.70094
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    Trastuzumab Deruxtecan (T-DXd) Resistance via Loss of HER2 Expression and Binding
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    Two novel red-FRET ERK bosensors in the 670-720 nm range
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    PROTAC-mediated structure–function disruption of CD26: a therapeutic strategy for driver-negative non-small cell lung cancer
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    Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer
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  81. Oct 2025
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    PERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape
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    Integrin-Piezo1 Axis Drives ECM Remodeling and Invasion of 3D Breast Epithelium
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    CircLRBA Promotes Epithelial-Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1
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    Interplay between malic enzyme 2, de novo serine synthesis, and the malate-aspartate shuttle drives metabolic adaptation in triple-negative breast cancer
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    Synergistic Reduction of Breast Cancer Cell Viability and Aggressiveness Through Dual Inhibition of APE1 Redox Function and STAT3 Signaling
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  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The deubiquitinase USP9X and E3 ligase WWP1 orchestrate IGF2BP2 ubiquitination homeostasis to drive TNBC progression and cisplatin sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500958/
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    YEATS4 reads histone crotonylation to promote fatty acid metabolism and cancer cell stemness
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    Microenvironmental signals combine to induce non-additive molecular and phenotypic responses in mammary epithelial cells
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    Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors
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