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Amphiregulin-mediated EGFR activation drives both intrinsic and acquired resistance to KRAS G12C inhibitors in KRAS G12C–mutant non-small cell lung cancer

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1. scibot 07 Jul 2026
  
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  DOI: 10.1038/s41388-026-03877-8
  
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nature.com/articles/s41388-026-03877-8
Jun 2026
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Zn(II) complexes derived from S-alkyl thiosemicarbazones: Synthesis, characterization, DFT, and antiproliferative, cytotoxic, antimigratory effects on human lung and breast cancer

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1. scibot 21 Jun 2026
  
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  DOI: 10.1016/j.inoche.2026.117072
  
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sciencedirect.com/science/article/pii/S1387700326009391
May 2026
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Gasdermin C reprograms metabolism through the CAMKK2-AMPK axis to promote lung adenocarcinoma progression and radioresistance

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1. scibot 27 May 2026
  
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  ATCCHTB-54
  
  DOI: 10.1016/j.celrep.2026.117427
  
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sciencedirect.com/science/article/pii/S221112472600505X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lipid Composition Alters Ferroptosis Sensitivity

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1. scibot 06 May 2026
  
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  DOI: 10.1158/0008-5472.CAN-24-4207
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13138121/
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Accumulated sotorasib-bound KRASG12C reactivates the MAPK pathway and drives sotorasib resistance via the DHX9-RAC1-PAK1 axis

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1. scibot 06 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117338
  
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sciencedirect.com/science/article/pii/S221112472600416X
Mar 2026
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CRISPR-Drug Combinatorial Screening Identifies Effective Combination Treatments for MTAP-deleted cancer

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1. scibot 27 Mar 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-1464
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13014710/
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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1. scibot 05 Mar 2026
  
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  DOI: 10.1002/2211-5463.70206
  
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febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70206
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Aspartate availability drives differential engagement of the malate-aspartate shuttle

1
1. scibot 04 Mar 2026
  
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  ATCC Cat#HTB-54
  
  DOI: 10.1016/j.molcel.2026.02.004
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12952686/
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Reconstruction of T cell infiltration in an osteosarcoma PDX-organoid interactive biobank for personalized immunotherapy

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1. scibot 03 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102644
  
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sciencedirect.com/science/article/pii/S2666379126000613
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cyclic di-GMP suppresses cancer metastasis by targeting proteasome 26S subunit non-ATPase 3 independently of STING

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1. scibot 07 Feb 2026
  
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  RRID:CVCL_0608
  
  DOI: 10.1038/s41392-025-02553-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12868630/
Jan 2026
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Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML

1
1. scibot 30 Jan 2026
  
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  ATCCHTB-54
  
  DOI: 10.1016/j.cmet.2026.01.001
  
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sciencedirect.com/science/article/pii/S155041312600001X
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ANP32A-mediated Histone 3 K27 Acetylation is Essential for Sotorasib Activity in KRAS-mutant Non-Small Cell Lung Cancer

1
1. scibot 06 Jan 2026
  
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  RRID:CVCL_0608
  
  DOI: 10.1016/j.jbc.2025.111110
  
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sciencedirect.com/science/article/pii/S002192582502962X
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

RAS mutation–specific responses to paralog- and state-selective RAS inhibitors

1
1. scibot 20 Dec 2025
  
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  RRID:CVCL_0608
  
  DOI: 10.1158/1541-7786.MCR-25-0319
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12710464/
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Structural characterization, DNA binding properties and anticancer activities of new tetrazole compounds

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1. scibot 03 Dec 2025
  
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  HTB-54
  
  DOI: 10.1016/j.molstruc.2025.144937
  
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sciencedirect.com:5037/science/article/pii/S002228602503577X
Nov 2025
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Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy

1
1. scibot 29 Nov 2025
  
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  RRID:CVCL_0608
  
  DOI: 10.1016/j.bcp.2025.117562
  
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sciencedirect.com:5037/science/article/pii/S0006295225008275
Sep 2025
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Pharmacologic interrogation of USP28 cellular function in p53 signaling

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.chembiol.2025.08.002
  
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sciencedirect.com/science/article/pii/S2451945625002326
Aug 2025
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Synthesis, Characterization and Antitumor Assessments of Sulfonamide-1,2,4-Triazole Compounds with EGRF inhibitory Potential: DFT Calculation, Molecular Docking, Molecular Dynamics, and MM/PBSA Approaches

1
1. scibot 26 Aug 2025
  
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  ATCC: HTB-54
  
  DOI: 10.1016/j.molstruc.2025.143733
  
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sciencedirect.com/science/article/pii/S0022286025023968
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Dose-dependent multifunctional effects of oxovanadium(IV) thiosemicarbazone complexes: A molecular modeling approach

1
1. scibot 26 Aug 2025
  
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  ATCC, HTB-54
  
  DOI: 10.1016/j.inoche.2025.115371
  
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sciencedirect.com/science/article/pii/S1387700325014881
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A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

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1. scibot 08 Aug 2025
  
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  RRID:CVCL_0608
  
  DOI: 10.1016/j.ccell.2025.07.006
  
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sciencedirect.com/science/article/pii/S1535610825003101
Apr 2025
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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1. scibot 19 Apr 2025
  
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  RRID:CVCL_0608
  
  DOI: 10.1111/febs.70099
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.70099
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Cytosolic cytochrome c represses ferroptosis

1
1. scibot 15 Apr 2025
  
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  ATCCHTB-54
  
  DOI: 10.1016/j.cmet.2025.03.014
  
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sciencedirect.com/science/article/pii/S1550413125001494
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial

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1. scibot 19 Mar 2025
  
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  RRID:CVCL_0608
  
  DOI: 10.1158/1078-0432.CCR-24-2310
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11911804/
Feb 2025
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Yeast TIA1 coordinates with Npl3 to promote ATG1 translation during starvation

1
1. scibot 20 Feb 2025
  
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  ATCCHTB-54
  
  DOI: 10.1016/j.celrep.2025.115316
  
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sciencedirect.com/science/article/pii/S2211124725000877
Jan 2025
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Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2

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1. scibot 04 Jan 2025
  
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  RRID:CVCL_0608
  
  DOI: 10.7554/eLife.89638
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11668523/
Apr 2024
aacrjournals.org aacrjournals.org

The immune suppressor IGSF1 as a potential target for cancer immunotherapy

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1. scibot 19 Apr 2024
  
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  RRID:CVCL_0608
  
  DOI: 10.1158/2326-6066.CIR-23-0817
  
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aacrjournals.org/cancerimmunolres/article/12/4/491/741941/The-Immune-Suppressor-IGSF1-as-a-Potential-Target
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Novel diarylated tacrine derivatives: Synthesis, characterization, anticancer, antiepileptic, antibacterial, and antifungal activities

1
1. scibot 10 Apr 2024
  
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  Calu1
  
  DOI: 10.1002/jbt.23706
  
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onlinelibrary.wiley.com/doi/10.1002/jbt.23706
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Reduced representative methylome profiling of cell-free DNA for breast cancer detection

1
1. scibot 02 Mar 2024
  
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  CVCL_0608
  
  DOI: 10.1186/s13148-024-01641-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10898043/
Feb 2024
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Tumoral and stromal hMENA isoforms impact tertiary lymphoid structure localization in lung cancer and predict immune checkpoint blockade response in patients with cancer

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1. scibot 13 Feb 2024
  
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  RRID:CVCL_0608
  
  DOI: 10.1016/j.ebiom.2024.105003
  
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sciencedirect.com/science/article/pii/S2352396424000380
Jan 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling

1
1. scibot 25 Jan 2024
  
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  RRID:CVCL_0608
  
  DOI: 10.1002/1878-0261.13554
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
Nov 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

1
1. scibot 12 Nov 2023
  
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  RRID: CVCL_0608
  
  DOI: 10.1002/ijc.34783
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34783
Jun 2023
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MEK inhibitor and anti-EGFR antibody overcome sotorasib resistance signals and enhance its antitumor effect in colorectal cancer cells

1
1. scibot 21 Jun 2023
  
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  RRID:CVCL_0608
  
  DOI: 10.1016/j.canlet.2023.216264
  
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sciencedirect.com/science/article/pii/S030438352300215X
Aug 2022
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Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression

1
1. scibot 23 Aug 2022
  
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  RRID:CVCL_0608
  
  DOI: 10.1016/j.molcel.2022.07.014
  
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sciencedirect.com/science/article/pii/S1097276522007109
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Cancer-associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications

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1. scibot 04 Aug 2022
  
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  RRID:CVCL_0608
  
  DOI: 10.1002/ijc.34127
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34127
Apr 2022
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Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes

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1. scibot 14 Apr 2022
  
  in Public
  
  RRID: CVCL_0608
  
  DOI: 10.1016/j.celrep.2022.110636
  
  Resource: (CLS Cat# 300141/p1546_Calu-1, RRID:CVCL_0608)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_0608
  
  What is this?
  
  RRID:CVCL_0608
Visit annotations in context

Tags

RRID:CVCL_0608

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722003886
Jun 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.

1
1. scibot 29 Jun 2021
  
  in Public
  
  RRID:CVCL_0608
  
  DOI: 10.1158/2159-8290.CD-20-0797
  
  Resource: (CLS Cat# 300141/p1546_Calu-1, RRID:CVCL_0608)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0608
  
  What is this?
  
  RRID:CVCL_0608
Visit annotations in context

Tags

RRID:CVCL_0608

Annotators

scibot

URL

cancerdiscovery.aacrjournals.org/content/11/6/1411
Jan 2020
www.sciencedirect.com www.sciencedirect.com

RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_0608
  
  DOI: 10.1016/j.chembiol.2019.12.005
  
  Resource: (CLS Cat# 300141/p1546_Calu-1, RRID:CVCL_0608)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_0608
  
  What is this?
  
  RRID:CVCL_0608 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_0608

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945619304015
Nov 2018
www.sciencedirect.com www.sciencedirect.com

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-54
  
  Curator: @Jmenke
  
  Resource used:
  
  (ICLC Cat# HTL95002, RRID:CVCL_0608)
  
  SciCrunch record: RRID:CVCL_0608
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0608 RRIDCUR:Missing
Visit annotations in context

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RRIDCUR:Missing

RRID:CVCL_0608

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0960982218307644
www.sciencedirect.com www.sciencedirect.com

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

1
1. scibot 05 Nov 2018
  
  in Public
  
  HTB-54
  
  Curator: @Jmenke
  
  Resource used:
  
  (ICLC Cat# HTL95002, RRID:CVCL_0608)
  
  SciCrunch record: RRID:CVCL_0608
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_0608 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:CVCL_0608

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867418300412