107 Matching Annotations
  1. Dec 2025
  2. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer
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    sciencedirect.com:5037/science/article/pii/S2666379125005518
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effect of extracellular vesicles in remodeling the tumor microenvironment by DNMT1 downregulation for enhanced cancer immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12612775/
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    An engineered cysteine sensor optimized for high-throughput screening identifies regulators of intracellular thiol levels
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    sciencedirect.com/science/article/pii/S2451945625003435
  6. Oct 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARP inhibitor and PRMT5 inhibitor synergy is independent of BRCA1/2 and MTAP status in breast cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12540990/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Olive Oil-Based High-Fat Diet Promotes Obesity-Driven Metastasis of Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12502211/
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    Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors
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    sciencedirect.com/science/article/pii/S2451945625002685
  10. Sep 2025
  11. 52.53.155.43 52.53.155.43
    2025.09.04.674332v2.full-html.html
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  12. Jul 2025
  13. www.sciencedirect.com www.sciencedirect.com
    Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis
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    sciencedirect.com/science/article/pii/S2666379125003258
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Curcumin Induces Homologous Recombination Deficiency by BRCA2 Degradation in Breast Cancer and Normal Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12248657/
  15. Jun 2025
  16. 52.53.155.43 52.53.155.43
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  17. May 2025
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Screening of Transcribed Super-Enhancers Identifies Drivers of Triple-Negative Breast Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534545/
  19. Apr 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Potentiating doxorubicin activity through BCL-2 inhibition in p53 wild-type and mutated triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11999952/
  21. Mar 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induction of Triple-Negative Breast Cancer Cell Death and Chemosensitivity Using mTORC2-Directed RNAi Nanomedicine
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    pmc.ncbi.nlm.nih.gov/articles/PMC11921867/
  23. Feb 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Manipulating the cGAS-STING Axis: advancing innovative strategies for osteosarcoma therapeutics
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    pmc.ncbi.nlm.nih.gov/articles/PMC11842356/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic Profiling of Breast Cancer Cell Lines: Unique and Shared Metabolites
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    pmc.ncbi.nlm.nih.gov/articles/PMC11816582/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol to identify small-molecule inhibitors against cancer drug resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11821401/
  27. Jan 2025
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fibroblast growth factor receptor four inhibitor FGF401 improves the efficacy of trastuzumab in FGFR4-overexpressing breast cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35271
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  30. Dec 2024
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-Cancer Analysis of Homologous Recombination Deficiency in Cell Lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC11621922/
  32. Nov 2024
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C19MC Drives Nucleolar Invasion of Mitochondria and Meiotic Nuclear Division in Human Cancers
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  34. www.biorxiv.org www.biorxiv.org
    Aberrant expression of CD14 in breast tumor cells is associated with poor outcome
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    biorxiv.org/content/10.1101/2024.11.07.622456v1
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  36. Sep 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
  38. www.sciencedirect.com www.sciencedirect.com
    Transient splicing inhibition causes persistent DNA damage and chemotherapy vulnerability in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124724011021
  39. www.sciencedirect.com www.sciencedirect.com
    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945624003234
  40. Aug 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetalax (Oxyphenisatin acetate, NSC 59687) and bisacodyl Cause Oncosis in Triple Negative Breast Cancer Cell lines by Poisoning Ion Exchange Membrane Protein TRPM4
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    ncbi.nlm.nih.gov/pmc/articles/PMC11322923/
  42. www.cell.com www.cell.com
    ADP-ribosylome analysis reveals homogeneous DNA-damage-induced serine ADP-ribosylation across wild-type and BRCA-mutant breast cancer cell lines
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    cell.com/cell-reports/fulltext/S2211-1247(24)00762-9
  43. aacrjournals.org aacrjournals.org
    Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer
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    aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
  44. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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    embopress.org/doi/full/10.15252/emmm.202012716
  45. Jul 2024
  46. www.sciencedirect.com www.sciencedirect.com
    Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis
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  47. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  48. May 2024
  49. aacrjournals.org aacrjournals.org
    Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1
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    aacrjournals.org/clincancerres/article/30/7/1338/741831/Preclinical-Characterization-of-AZD9574-a-Blood
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078187/
  51. www.science.org www.science.org
    Phenotypic targeting using magnetic nanoparticles for rapid characterization of cellular proliferation regulators
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    science.org/doi/10.1126/sciadv.adj1468
  52. Apr 2024
  53. www.sciencedirect.com www.sciencedirect.com
    A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response
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    sciencedirect.com/science/article/pii/S2666379124001800
  54. www.sciencedirect.com www.sciencedirect.com
    Transcriptomics studies reveal functions of Transglutaminase 2 in breast cancer cells using membrane permeable and impermeable inhibitors
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    sciencedirect.com/science/article/pii/S0022283624001645
  55. Mar 2024
  56. www.sciencedirect.com www.sciencedirect.com
    Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides
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    sciencedirect.com/science/article/pii/S2211124724003127
  57. 52.53.155.43 52.53.155.43
    Low-dose Decitabine enhances the efficacy of viral cancer vaccines for immunotherapy.
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  58. Feb 2024
  59. 52.53.155.43 52.53.155.43
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein Kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10844833/
  61. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424000102
  62. Dec 2023
  63. www.sciencedirect.com www.sciencedirect.com
    PRMT blockade induces defective DNA replication stress response and synergizes with PARP inhibition
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    sciencedirect.com/science/article/pii/S2666379123005438
  64. www.sciencedirect.com www.sciencedirect.com
    Heterogeneity and transcriptional drivers of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124723015760
  65. Nov 2023
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC1-C INTEGRATES AEROBIC GLYCOLYSIS WITH SUPPRESSION OF OXIDATIVE PHOSPHORYLATION IN TRIPLE-NEGATIVE BREAST CANCER STEM CELLS
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    ncbi.nlm.nih.gov/pmc/articles/PMC10616323/
  67. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers
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    pubmed.ncbi.nlm.nih.gov/37279095/
  68. Oct 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC
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    ncbi.nlm.nih.gov/pmc/articles/PMC10589312/
  70. 52.53.155.43 52.53.155.43
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  71. dx.doi.org dx.doi.org
    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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    dx.doi.org/10.1158/2767-9764.CRC-23-0236
  72. Sep 2023
  73. 52.53.155.43 52.53.155.43
    ALDH1A3 promotes invasion and metastasis in triple-negative breast cancer by regulating the plasminogen activation pathway
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    52.53.155.43/2f8328dc1dc33e6a3563ba1fede45bc3b7e7ee78/Molecular Oncology - 2023 - Bharadwaj-html.html
  74. Aug 2023
  75. 52.53.155.43 52.53.155.43
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  76. Jul 2023
  77. 52.53.155.43 52.53.155.43
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  78. Apr 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  80. Mar 2023
  81. academic.oup.com academic.oup.com
    Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad172/7079642
  82. Dec 2022
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  84. Jun 2022
  85. www.sciencedirect.com www.sciencedirect.com
    MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels
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    sciencedirect.com/science/article/pii/S2589004222007301
  86. www.sciencedirect.com www.sciencedirect.com
    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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    sciencedirect.com/science/article/pii/S2211124722006453
  87. May 2022
  88. www.sciencedirect.com www.sciencedirect.com
    Gold(III)-P-chirogenic complex induce mitochondrial dysfunction in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2589004222006113
  89. Mar 2022
  90. www.sciencedirect.com www.sciencedirect.com
    Proteome-centric cross-omics characterization and integrated network analyses of triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2211124722001875
  91. www.sciencedirect.com www.sciencedirect.com
    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124722001759
  92. Feb 2022
  93. www.sciencedirect.com www.sciencedirect.com
    An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer
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    sciencedirect.com/science/article/pii/S2666379122000258
  94. Dec 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An avian embryo patient-derived xenograft model for preclinical studies of human breast cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC8608609/
  96. Nov 2021
  97. www.sciencedirect.com www.sciencedirect.com
    The allergy mediator histamine confers resistanceto immunotherapy in cancer patients via activationof the macrophage histamine receptor H1
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    sciencedirect.com/science/article/pii/S1535610821006024
  98. www.sciencedirect.com www.sciencedirect.com
    A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
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    sciencedirect.com/science/article/pii/S2211124721014303
  99. Sep 2021
  100. www.sciencedirect.com www.sciencedirect.com
    Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2451945621004001
  101. www.sciencedirect.com www.sciencedirect.com
    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
  102. Aug 2021
  103. jitc.bmj.com jitc.bmj.com
    Novel oncolytic adenovirus expressing enhanced cross-hybrid IgGA Fc PD-L1 inhibitor activates multiple immune effector populations leading to enhanced tumor killing in vitro, in vivo and with patient-derived tumor organoids
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  104. www.cell.com www.cell.com
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    cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
  105. www.sciencedirect.com www.sciencedirect.com
    Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
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    sciencedirect.com/science/article/pii/S1097276517307141
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The GEF‐H1/PKD3 signaling pathway promotes the maintenance of triple negative breast cancer stem cells
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32798
  107. www.sciencedirect.com www.sciencedirect.com
    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S2405471219303874
  108. Jul 2021
  109. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion
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    sciencedirect.com/science/article/pii/S1550413119300208
  110. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
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    sciencedirect.com/science/article/pii/S2211124719311520
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    Mesenchymal Stem/Stromal Cell Engulfment Reveals Metastatic Advantage in Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719307235
  112. www.sciencedirect.com www.sciencedirect.com
    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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    sciencedirect.com/science/article/pii/S2451945619301746
  113. www.sciencedirect.com www.sciencedirect.com
    Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719306953
  114. www.nature.com www.nature.com
    A chemical toolbox for the study of bromodomains and epigenetic signaling
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    nature.com/articles/s41467-019-09672-2
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5726799/
  116. May 2021
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limited inhibition of multiple nodes in a driver network blocks metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8128439/
  118. www.sciencedirect.com www.sciencedirect.com
    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    sciencedirect.com/science/article/pii/S1097276520305815
  119. www.sciencedirect.com www.sciencedirect.com
    Deciphering the signaling network of breast cancer improves drug sensitivity prediction
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    sciencedirect.com/science/article/pii/S2405471221001113
  120. Apr 2021
  121. www.sciencedirect.com www.sciencedirect.com
    Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets
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    sciencedirect.com/science/article/pii/S1550413120305453
  122. Mar 2021
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intein-mediated cytoplasmic reconstitution of a split toxin enables selective cell ablation in mixed populations and tumor xenografts
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  126. Nov 2020
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  131. Sep 2020
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  136. Jan 2020
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