196 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Caloric Restriction Enhances the Efficacy of Anti-Androgen Therapy in Prostate Cancer by Inhibiting Androgen Receptor Translation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12535181/
  3. Oct 2025
  4. 54.241.53.176 54.241.53.176
    1-s2.0-S2666247725001356-main-html.html
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    54.241.53.176/3038b4b2ad0d9f2b6fba92dadb06414ded6c8b0a/1-s2.0-S2666247725001356-main-html.html
  5. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated Omics and Multi-Cohort Analyses Identify an Enhancer Variant Linking Ferroptosis to Precision Therapy in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485374/
  7. Sep 2025
  8. www.nature.com www.nature.com
    Induction of ferroptosis in prostate cancer by CCDC719-13 via TRIM21-mediated ubiquitination of SLC7A11
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    nature.com/articles/s41418-025-01580-x
  9. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Enzalutamide-Resistant STEAP4+ MyoCAF Secrete Phosphatidylcholine to Foster Progression by Activating Stemness in Hormone-Sensitive Prostate Cancer
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202510602
  10. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422501781X-main-html.html
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    52.53.155.43/f995d4046e40952b58ad424165ec4ce7948925e5/1-s2.0-S258900422501781X-main-html.html
  11. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1002/prp2.70173
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor associated neutrophils promote prostate cancer progression by mediating neutrophil trap secretion through PSMA1- NF-κB-HIF-1α signaling axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399615/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Direct co-targeting of Bcl-xL and Mcl-1 exhibits synergistic effects in AR-V7-expressing CRPC models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12368576/
  14. Aug 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tissue-dependent mechanosensing by cells derived from human tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12328224/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322234/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anticancer activity of triterpene glycosides from the sea star Solaster pacificus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12322260/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Androgen receptor–mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12315708/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AR+TREM2+ macrophage induced pathogenic immunosuppression promotes prostate cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12307935/
  21. Jul 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Applying Unbiased, Functional Criteria Allows Selection of Novel Cyclic Peptides for Effective Targeted Drug Delivery to Malignant Prostate Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12298539/
  23. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
  24. www.science.org www.science.org
    Impaired mitochondrial metabolism is a critical cancer vulnerability for MYC inhibitors
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    science.org/doi/10.1126/sciadv.adw5228
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260511/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transcriptional profiling clarifies a program of enzalutamide extreme non-response in lethal prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12234718/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695179/
  28. Jun 2025
  29. www.sciencedirect.com www.sciencedirect.com
    Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
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    sciencedirect.com/science/article/pii/S1097276525005040
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ADT increases prostate cancer cell invasion via altering AR/SALL4/SOX2-OCT4 stem cell signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12176959/
  31. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Ezetimibe Engineered L14-8 Suppresses Advanced Prostate Cancer by Activating PLK1/TP53-SAT1-Induced Ferroptosis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202504192
  32. www.sciencedirect.com www.sciencedirect.com
    Ribosomal RNA transcription regulates splicing through ribosomal protein RPL22
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    sciencedirect.com/science/article/pii/S2451945625001734
  33. www.sciencedirect.com www.sciencedirect.com
    Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity
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    sciencedirect.com/science/article/pii/S0022356525398472
  34. 52.53.155.43 52.53.155.43
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    An integrated proteomic portrait of prostate cancer progression
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    sciencedirect.com/science/article/pii/S2211124725005996
  36. www.cell.com www.cell.com
    BCL2 drives castration resistance in castration-sensitive prostate cancer by orchestrating reciprocal crosstalk between oncogenic pathways
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    cell.com/cell-reports/fulltext/S2211-1247(25)00550-9
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bromodomain and Extra-Terminal Family Proteins BRD2, BRD3, and BRD4 Contribute to H19-Dependent Transcriptional Regulation of Cell Adhesion Molecules, Modulating Metastatic Dissemination Program in Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12101203/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC12129099/
  39. www.sciencedirect.com www.sciencedirect.com
    Cholesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer
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    sciencedirect.com/science/article/pii/S2211124725005637
  40. May 2025
  41. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70065
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A
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    pmc.ncbi.nlm.nih.gov/articles/PMC12038057/
  43. 52.53.155.43 52.53.155.43
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  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Emerin Dysregulation Drives the Very-Small-Nuclear Phenotype and Lineage Plasticity That Associate with a Clinically Aggressive Subtype of Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079098/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12019391/
  47. www.sciencedirect.com www.sciencedirect.com
    DHA suppresses hormone-sensitive and castration-resistant prostate cancer growth by decreasing de novo lipogenesis
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    sciencedirect.com/science/article/pii/S1388198125000423
  48. Apr 2025
  49. 52.53.155.43 52.53.155.43
    rational-design-and-development-of-selective-brd7-bromodomain-inhibitors-and-their-activity-in-prostate-cancer-html.html
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    CD36-mediated endocytosis of proteolysis-targeting chimeras
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    sciencedirect.com/science/article/pii/S0092867425003861
  51. aacrjournals.org aacrjournals.org
    A B7-H3-targeted CD28 bispecific antibody enhances the activity of anti-PD1 and CD3 T-cell engager immunotherapies
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    aacrjournals.org/mct/article/24/3/331/752086/A-B7-H3-Targeted-CD28-Bispecific-Antibody-Enhances
  52. www.nature.com www.nature.com
    CD117/c-kit defines a prostate CSC-like subpopulation driving progression and TKI resistance
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    nature.com/articles/s41598-021-81126-6
  53. www.sciencedirect.com www.sciencedirect.com
    Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer
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    sciencedirect.com/science/article/pii/S0925443925000675
  54. www.sciencedirect.com www.sciencedirect.com
    FMNL2/SRC-mediated androgen receptor translocation into the nucleus promotes enzalutamide resistance of prostate cancer
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    sciencedirect.com/science/article/pii/S2589004225004663
  55. Mar 2025
  56. www.cell.com www.cell.com
    Small-molecule RNA therapeutics to target prostate cancer
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    cell.com/cancer-cell/abstract/S1535-6108(25)00079-0
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Secretome Analysis of Prostate Cancer Cell Lines Reveals Cell Cycle-Dependent PSA Secretion and Potential Biomarkers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11899065/
  58. Feb 2025
  59. link.springer.com link.springer.com
    157Gd-DOTA-PSMA as theranostic bio-gadolinium agent for prostate cancer targeted gadolinium neutron capture therapy
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    link.springer.com/article/10.1007/s00432-025-06136-7
  60. aacrjournals.org aacrjournals.org
    Clonal Lineage Tracing with Somatic Delivery of Recordable Barcodes Reveals Migration Histories of Metastatic Prostate Cancer
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    aacrjournals.org/cancerdiscovery/article/14/10/1990/748601/Clonal-Lineage-Tracing-with-Somatic-Delivery-of
  61. www.sciencedirect.com www.sciencedirect.com
    Synonymous mutations promote tumorigenesis by disrupting m6A-dependent mRNA metabolism
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    sciencedirect.com/science/article/pii/S0092867425000959
  62. 52.53.155.43 52.53.155.43
    mct-24-0327-html.html
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  63. Jan 2025
  64. www.sciencedirect.com www.sciencedirect.com
    Reciprocal regulation between DNMT3A/3B and microRNAs miRs-299-3p/-30e is a causal factor for the downregulation of microRNAs targeting Androgen Receptor in prostate cancer.
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    sciencedirect.com/science/article/pii/S2405844025003287
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11733533/
  66. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Clinical significance of stratifying prostate cancer patients through specific circulating genes
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13805
  67. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial uncouplers inhibit oncogenic E2F1 activity and prostate cancer growth
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    sciencedirect.com/science/article/pii/S266637912400661X
  68. Dec 2024
  69. www.science.org www.science.org
    Castration-resistant prostate cancer is resensitized to androgen deprivation by autophagy-dependent apoptosis induced by blocking SKP2
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    science.org/doi/10.1126/scisignal.adk4122
  70. www.sciencedirect.com www.sciencedirect.com
    Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes
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    sciencedirect.com/science/article/pii/S2451945624004409
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Splicing Factor Requirements for Androgen Receptor Variant Synthesis in Advanced Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612623/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Characterization of ARX517, a Site-Specific Stable PSMA-Targeted Antibody–Drug Conjugate for the Treatment of Metastatic Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612621/
  73. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
  74. Nov 2024
  75. www.sciencedirect.com www.sciencedirect.com
    PI3K/Akt inhibition promotes AR activity and prostate cancer cell proliferation through p35-CDK5 modulation
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    sciencedirect.com/science/article/pii/S0925443924005623
  76. Oct 2024
  77. www.sciencedirect.com www.sciencedirect.com
    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
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    sciencedirect.com/science/article/pii/S2666379124004828
  78. aacrjournals.org aacrjournals.org
    Cytoplasmic Localization of Prostate-Specific Membrane Antigen Inhibitors May Confer Advantages for Targeted Cancer Therapies
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    aacrjournals.org/cancerres/article/81/8/2234/670605/Cytoplasmic-Localization-of-Prostate-Specific
  79. Sep 2024
  80. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13728
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Proteogenomics of Prostate Cancer Radioresistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC11411600/
  82. www.sciencedirect.com www.sciencedirect.com
    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610824003179
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MED12 and CDK8/19 modulate androgen receptor activity and enzalutamide response in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11398899/
  84. aacrjournals.org aacrjournals.org
    Squalene epoxidase metabolic dependency is a targetable vulnerability in castration-resistant prostate cancer
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    aacrjournals.org/cancerres/article/82/17/3032/708286/Squalene-Epoxidase-Metabolic-Dependency-Is-a
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular Osteopontin Promotes the Release of TNFα by Mast Cells to Restrain Neuroendocrine Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369624/
  86. www.sciencedirect.com www.sciencedirect.com
    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
  87. Aug 2024
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rational Design and Development of Selective BRD7 Bromodomain Inhibitors and Their Activity in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10641717/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WNT5A is a putative epi‐driver of prostate cancer metastasis to the bone
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335815/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11315984/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAS3681, an androgen receptor antagonist, prevents drug resistance driven by aberrant androgen receptor signaling in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11306513/
  92. www.biorxiv.org www.biorxiv.org
    Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer
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    biorxiv.org/content/10.1101/2024.07.10.602941v2
  93. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Assessments of prostate cancer cell functions highlight differences between a pan-PI3K/mTOR inhibitor, gedatolisib, and single-node inhibitors of the PI3K/AKT/mTOR pathway
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13703
  94. www.sciencedirect.com www.sciencedirect.com
    RPL22 is a tumor suppressor in MSI-high cancers and a splicing regulator of MDM4
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    sciencedirect.com/science/article/pii/S2211124724009720
  95. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  96. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/4e85ba1ed1516c780407b3a64dcb4d2814a68c56/Molecular Oncology - 2023 - Gonthier - Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic mitochondrial tricarboxylic-html.html
  97. Jul 2024
  98. www.embopress.org www.embopress.org
    Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer
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  102. Jun 2024
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  105. May 2024
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  108. Apr 2024
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  113. Mar 2024
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  117. Feb 2024
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  123. Jan 2024
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  130. Dec 2023
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  133. Nov 2023
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  136. Oct 2023
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  140. Sep 2023
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  143. Aug 2023
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  151. Jun 2023
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  154. May 2023
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  156. Apr 2023
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  160. Mar 2023
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    Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer
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  162. Feb 2023
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  165. Dec 2022
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  167. Oct 2022
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  169. Sep 2022
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  171. Aug 2022
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  177. Jul 2022
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  180. Jun 2022
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  184. May 2022
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  186. Apr 2022
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  190. Mar 2022
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    Multi-omics and Pathway Analysis Identify Potential Roles for Tumour N-Acetyl Aspartate Accumulation in Murine Models of Castration Resistant Prostate Cancer
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  193. Feb 2022
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    A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
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  197. Jan 2022
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    Novel role of prostate cancer risk variant rs7247241 on PPP1R14A isoform transition through allelic TF binding and CpG methylation
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    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
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  200. Nov 2021
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    G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer
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  203. Oct 2021
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  205. Sep 2021
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    A feedback loop between the androgen receptor and 6-phosphogluoconate dehydrogenase (6PGD) drives prostate cancer growth
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  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parallel Reporter Assays Identify Altered Regulatory Role of rs684232 in Leading to Prostate Cancer Predisposition
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  208. Aug 2021
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  212. Jul 2021
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  217. Jun 2021
  218. cancerres.aacrjournals.org cancerres.aacrjournals.org
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  219. May 2021
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  222. Apr 2021
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  224. Feb 2021
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    STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer
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  227. Jan 2021
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    Post-transcriptional Gene Regulation by MicroRNA-194 Promotes Neuroendocrine Transdifferentiation in Prostate Cancer
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  229. Nov 2020
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  231. Oct 2020
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    Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
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  233. Sep 2020
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    AR phosphorylation and CHK2 kinase activity regulates IR-stabilized AR–CHK2 interaction and prostate cancer survival
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    Tumor Microenvironment-Derived NRG1 Promotes Antiandrogen Resistance in Prostate Cancer
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  238. Aug 2020
  239. www.nature.com www.nature.com
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  240. Jan 2020
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  243. Nov 2018
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    Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import
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  250. Nov 2017
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    Replication Study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
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