Hypothesis

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Last 7 days
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer

1
1. scibot 17 Dec 2025
  
  in Public
  
  ATCC (American Type Culture Collection)HTB-123
  
  DOI: 10.1016/j.xcrm.2025.102478
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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scibot

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sciencedirect.com:5037/science/article/pii/S2666379125005518
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors

1
1. scibot 01 Oct 2025
  
  in Public
  
  CVCL_1183
  
  DOI: 10.1016/j.chembiol.2025.09.003
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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scibot

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sciencedirect.com/science/article/pii/S2451945625002685
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Acetalax and Bisacodyl for the Treatment of Triple-Negative Breast Cancer: A Combined Molecular and Preclinical Study

1
1. scibot 07 Mar 2025
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1158/2767-9764.CRC-24-0435
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRID:CVCL_1183
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RRID:CVCL_1183

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11869203/
Aug 2024
transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com

iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer

1
1. scibot 02 Aug 2024
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1186/s41231-024-00161-3
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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scibot

URL

transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer

1
1. scibot 04 May 2024
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1158/0008-5472.CAN-23-3046
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Engineering CD276/B7-H3-targeted antibody-drug conjugates with enhanced cancer-eradicating capability

1
1. scibot 02 Dec 2023
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1016/j.celrep.2023.113503
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @jmitrevska
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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sciencedirect.com/science/article/pii/S2211124723015152
Jun 2023
aacrjournals.org aacrjournals.org

Targeted MDM2 degradation reveals a new vulnerability for p53 inactivated triple negative breast cancer

1
1. scibot 10 Jun 2023
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1158/2159-8290.CD-22-1131
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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URL

aacrjournals.org/cancerdiscovery/article/13/5/1210/726189/Targeted-MDM2-Degradation-Reveals-a-New
Nov 2022
www.nature.com www.nature.com

Carboxyl-terminal modulator protein facilitates tumor metastasis in triple-negative breast cancer

1
1. scibot 22 Nov 2022
  
  in Public
  
  CVCL_1183
  
  DOI: 10.1038/s41417-022-00559-x
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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nature.com/articles/s41417-022-00559-x
Feb 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting Pyruvate Kinase M2 phosphorylation reverses aggressive cancer phenotypes

1
1. scibot 16 Feb 2022
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1158/0008-5472.CAN-20-4190
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRID:CVCL_1183
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RRID:CVCL_1183

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8373815/
Aug 2021
link.springer.com link.springer.com

YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

1
1. scibot 28 Aug 2021
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1007/s13402-021-00630-z
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
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  RRID:CVCL_1183
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RRID:CVCL_1183

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URL

link.springer.com/article/10.1007/s13402-021-00630-z
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

1
1. scibot 30 Jul 2021
  
  in Public
  
  Human: DU4475
  
  DOI: 10.1016/j.celrep.2019.08.076
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRID:CVCL_1183 RRIDCUR:Missing
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RRID:CVCL_1183

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719311313
www.sciencedirect.com www.sciencedirect.com

Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

1
1. scibot 22 Jul 2021
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1016/j.ccell.2021.06.016
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRID:CVCL_1183
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RRID:CVCL_1183

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scibot

URL

sciencedirect.com/science/article/pii/S153561082100338X
May 2021
www.sciencedirect.com www.sciencedirect.com

PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1016/j.molcel.2020.08.018
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRID:CVCL_1183
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RRID:CVCL_1183

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URL

sciencedirect.com/science/article/pii/S1097276520305815
www.sciencedirect.com www.sciencedirect.com

Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
  in Public
  
  HTB-123
  
  DOI: 10.1016/j.cels.2021.04.002
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRID:CVCL_1183 RRIDCUR:Missing
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RRID:CVCL_1183

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2405471221001113
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

1
1. scibot 29 Apr 2021
  
  in Public
  
  Cat#ACC 427
  
  DOI: 10.1016/j.cmet.2020.10.012
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1183
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RRID:CVCL_1183

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1550413120305453
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.7554/eLife.56913
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1183
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RRID:CVCL_1183

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7363447/
onlinelibrary.wiley.com onlinelibrary.wiley.com

FGF13 promotes metastasis of triple‐negative breast cancer

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_1183
  
  DOI: 10.1002/ijc.32874
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1183
  
  Curator comments: DU4475 cell line ATCC Cat# HTB-123
  
  What is this?
  
  RRID:CVCL_1183
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RRID:CVCL_1183

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URL

onlinelibrary.wiley.com/doi/10.1002/ijc.32874
www.sciencedirect.com www.sciencedirect.com

Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer

1
1. scibot 03 Sep 2020
  
  in Public
  
  Human: DU4475
  
  DOI: 10.1016/j.celrep.2019.12.056
  
  Resource: (ATCC Cat# CRL-7921, RRID:CVCL_1183)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1183
  
  What is this?
  
  RRID:CVCL_1183 RRIDCUR:Missing
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RRID:CVCL_1183

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719317139