Hypothesis

26 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Eradicating Drug Tolerant Persister Cells in EGFR-Mutated Non-Small Cell Lung Cancer by Targeting TROP2 with CAR-T cellular therapy

1
1. scibot 07 Sep 2025
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1158/2159-8290.CD-24-1515
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12374242/
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses

1
1. scibot 12 Aug 2025
  
  in Public
  
  CVCL_1269
  
  DOI: 10.1126/sciimmunol.adr1105
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC7617988/
Jul 2025
www.science.org www.science.org

Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses

1
1. scibot 08 Jul 2025
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1126/sciimmunol.adr1105
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

science.org/doi/10.1126/sciimmunol.adr1105
aacrjournals.org aacrjournals.org

Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates

1
1. scibot 04 Jul 2025
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1158/1535-7163.MCT-23-0622
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation

1
1. scibot 11 Jun 2025
  
  in Public
  
  ATCCCRL-2871
  
  DOI: 10.1016/j.chembiol.2025.05.005
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2451945625001667
May 2025
link.springer.com link.springer.com

Retroelement co-option disrupts the cancer transcriptional programme

1
1. scibot 21 May 2025
  
  in Public
  
  CVCL_1269
  
  DOI: 10.1186/s13073-025-01479-9
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

link.springer.com/article/10.1186/s13073-025-01479-9
www.sciencedirect.com www.sciencedirect.com

MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer

1
1. scibot 20 May 2025
  
  in Public
  
  ATCCCat# CRL-2871
  
  DOI: 10.1016/j.celrep.2025.115722
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725004930
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma

1
1. scibot 29 Mar 2025
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.molcel.2025.03.001
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276525001947
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment

1
1. scibot 16 Jan 2025
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1038/s41467-024-55378-5
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11695629/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma

1
1. scibot 05 Dec 2024
  
  in Public
  
  CVCL_1269
  
  DOI: 10.1016/j.celrep.2024.115026
  
  Resource: (RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724013779
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR

1
1. scibot 06 Feb 2024
  
  in Public
  
  ATCCCRL-2871
  
  DOI: 10.1016/j.devcel.2024.01.010
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1534580724000303
Oct 2023
www.cell.com www.cell.com

PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C

1
1. scibot 06 Oct 2023
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.celrep.2023.113041
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

cell.com/cell-reports/fulltext/S2211-1247(23)01052-5
Aug 2023
52.53.155.43 52.53.155.43

L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab

2
1. scibot 18 Aug 2023
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.xcrm.2023.101142
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
2. scibot 10 Aug 2023
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.xcrm.2023.101142
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
www.sciencedirect.com www.sciencedirect.com

Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer

1
1. scibot 04 Aug 2023
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.ccell.2023.07.005
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610823002453
Jun 2023
aacrjournals.org aacrjournals.org

RBM10 loss promotes EGFR-driven lung cancer and confers sensitivity to spliceosome inhibition

1
1. scibot 03 Jun 2023
  
  in Public
  
  RRID: CVCL_1269
  
  DOI: 10.1158/0008-5472.CAN-22-1549
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

aacrjournals.org/cancerres/article/83/9/1490/726058/RBM10-Loss-Promotes-EGFR-Driven-Lung-Cancer-and
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pharmaceutical Reactivation of Attenuated Apoptotic Pathways Leads to Elimination of Osimertinib Drug-Tolerant Cells

1
1. scibot 29 Mar 2023
  
  in Public
  
  RRID: CVCL_1269
  
  DOI: 10.1158/2767-9764.CRC-22-0066
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10035388/
Dec 2022
www.sciencedirect.com www.sciencedirect.com

EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancer

1
1. scibot 18 Dec 2022
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.celrep.2022.111827
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124722017193
Oct 2022
www.nature.com www.nature.com

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

1
1. scibot 11 Oct 2022
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1038/s41467-022-33430-6
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

nature.com/articles/s41467-022-33430-6
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

EGFR inhibition enhances the cellular uptake and antitumor-activity of the HER3 antibody drug conjugate HER3-DXd

1
1. scibot 06 Jul 2022
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1158/0008-5472.CAN-21-2426
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8732289/
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer

1
1. scibot 11 Aug 2021
  
  in Public
  
  ATCCCRL-2871
  
  DOI: 10.7554/eLife.66524
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer

1
1. scibot 09 Jul 2021
  
  in Public
  
  CVCL_1269
  
  DOI: 10.1016/j.ebiom.2021.103457
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396421002504
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.ccell.2019.12.006
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1269
Visit annotations in context

Tags

RRID:CVCL_1269

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819305768
Jan 2020
www.sciencedirect.com www.sciencedirect.com

A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.celrep.2019.11.018
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_1269

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719314895
www.sciencedirect.com www.sciencedirect.com

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1269
  
  DOI: 10.1016/j.cell.2019.06.014
  
  Resource: (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1269
  
  What is this?
  
  RRID:CVCL_1269 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_1269

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867419306774
Nov 2017
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_1269
  
  Curator: @gabimpine
  
  Resource used:
  
  (ATCC Cat# CRL-2871, RRID:CVCL_1269)
  
  SciCrunch record: RRID:CVCL_1269
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1269 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_1269

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5345931/