61 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PARG regulates the proteasomal degradation of TARG1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13332792/
  3. Jun 2026
  4. www.mdpi.com www.mdpi.com
    Targeting Steroid-Metabolizing Enzymes with 15β-Substituted Estrone Analogues: Dual Discovery of AKR1C2/17β-HSD1 Inhibitors and a Fluorescent 17β-HSD1 Ligand
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    mdpi.com/2072-6694/18/12/1889
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13226670/
  6. May 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BMAL2 is a druggable target for ovarian clear cell carcinoma (OCCC)
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    pmc.ncbi.nlm.nih.gov/articles/PMC13179388/
  8. Apr 2026
  9. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CCDC80 suppresses high-grade serous ovarian cancer migration via negative regulation of B7-H3
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70235
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic and Ongoing De Novo L1 Retrotransposition Contributes to Genome Plasticity and Intrapatient Heterogeneity in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055634/
  11. Mar 2026
  12. www.sciencedirect.com www.sciencedirect.com
    A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy
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    sciencedirect.com/science/article/pii/S0092867426002692
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor‐Infiltrating Nociceptor Neurons in Ovarian Cancer Treatment Resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13004430/
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Metabolome analysis identified exogenous cholesterol within lipid rafts that activate the Akt/mTOR signaling pathway in epithelial ovarian cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.70401
  15. Feb 2026
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70227
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    Inhibition of replication origins and ATR synergistically activates the innate immune system in cancer cells
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    sciencedirect.com/science/article/pii/S2405844026001155
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mesothelial cells promote peritoneal invasion and metastasis of ascites-derived ovarian cancer cells through spheroid formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12880548/
  19. www.science.org www.science.org
    Mesothelial cells promote peritoneal invasion and metastasis of ascites-derived ovarian cancer cells through spheroid formation
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    science.org/doi/10.1126/sciadv.adu5944
  20. Jan 2026
  21. www.thno.org www.thno.org
    WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer
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    thno.org/v10p0537.htm
  22. Nov 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594208/
  24. Aug 2025
  25. www.sciencedirect.com www.sciencedirect.com
    Multi-omics analysis reveals the attenuation of the interferon pathway as a driver of chemo-refractory ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379125003891
  26. www.sciencedirect.com www.sciencedirect.com
    Coordinated protein modules define DNA damage responses to carboplatin at single-cell resolution in human ovarian carcinoma models
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    sciencedirect.com/science/article/pii/S2666379125003684
  27. www.biorxiv.org www.biorxiv.org
    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    biorxiv.org/content/10.1101/2025.08.10.669554v1
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Azenosertib Is a Potent and Selective WEE1 Kinase Inhibitor with Broad Antitumor Activity Across a Range of Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12314526/
  29. Jul 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11543919/
  31. www.biorxiv.org www.biorxiv.org
    Recapitulating physiologically relevant oxygen levels and extracellular matrix remodeling in patient-derived tumor-immune tunable models reveal targeting opportunities for immunologically cold high-grade serous tumors
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    biorxiv.org/content/10.1101/2025.06.23.661098v1
  32. Jun 2025
  33. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70067
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    1-s2.0-S2589004225008168-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12145850/
  35. May 2025
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70051
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534535/
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    1-s2.0-S2589004225008168-main-html.html
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  39. Apr 2025
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  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962398/
  42. Feb 2025
  43. www.sciencedirect.com www.sciencedirect.com
    Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors
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    sciencedirect.com/science/article/pii/S109727652500098X
  44. Jan 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11700143/
  46. Nov 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Solid tumor immunotherapy using NKG2D-based adaptor CAR T cells
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    sciencedirect.com/science/article/pii/S2666379124005986
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multicompartmentalized Microvascularized Tumor-on-a-Chip to Study Tumor-Stroma Interactions and Drug Resistance in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11538101/
  49. Aug 2024
  50. www.liebertpub.com www.liebertpub.com
    The Microenvironment of Solid Tumors: Components and Current Challenges of Tumor-on-a-Chip Models
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    liebertpub.com/doi/10.1089/ten.teb.2024.0088
  51. www.tandfonline.com www.tandfonline.com
    Novel chromobox 2 inhibitory peptide decreases tumor progression
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    tandfonline.com/doi/full/10.1080/14728222.2023.2218614
  52. Jun 2024
  53. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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    cell.com/iscience/abstract/S2589-0042(24)01200-8
  54. www.biorxiv.org www.biorxiv.org
    Multicompartmentalized microvascularized tumor-on-a-chip to study tumor-stroma interactions and drug resistance in ovarian cancer
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    biorxiv.org/content/10.1101/2024.05.29.596456v1
  55. Apr 2024
  56. onlinelibrary.wiley.com onlinelibrary.wiley.com
    VDX-111, a novel small molecule, induces necroptosis to inhibit ovarian cancer progression
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    onlinelibrary.wiley.com/doi/10.1002/mc.23721
  57. Feb 2024
  58. 52.53.155.43 52.53.155.43
    cd-23-0954-html.html
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A revised molecular model of ovarian cancer biomarker CA125 (MUC16) enabled by long-read sequencing
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    ncbi.nlm.nih.gov/pmc/articles/PMC10829539/
  60. Oct 2023
  61. www.sciencedirect.com www.sciencedirect.com
    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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    sciencedirect.com/science/article/pii/S1097276523007505
  62. Sep 2023
  63. dx.doi.org dx.doi.org
    RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells
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    dx.doi.org/10.1093/nar/gkad733
  64. Jul 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated mesothelial cells are regulated by the anti-Müllerian hormone axis
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    sciencedirect.com/science/article/pii/S2211124723007416
  66. Jun 2023
  67. www.tandfonline.com www.tandfonline.com
    Novel chromobox 2 inhibitory peptide decreases tumor progression
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    tandfonline.com/doi/full/10.1080/14728222.2023.2218614
  68. Apr 2023
  69. www.sciencedirect.com www.sciencedirect.com
    Actionable spontaneous antibody responses antagonize malignant progression in ovarian carcinoma
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    sciencedirect.com/science/article/pii/S0090825823001671
  70. Feb 2023
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DUSP activity as a treatment for high grade serous ovarian carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357222/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357105/
  73. Aug 2022
  74. www.sciencedirect.com www.sciencedirect.com
    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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    sciencedirect.com/science/article/pii/S2211124722009949
  75. Jul 2022
  76. 52.53.155.43 52.53.155.43
    cir-22-0088-html.html
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  77. Jun 2022
  78. 52.53.155.43 52.53.155.43
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    52.53.155.43/ab9f52410f4c75a7a2713f4530b957e6dadc45f9/mct-21-0682-html.html
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SETDB1–TRIM28 complex suppresses antitumor immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8647838/
  80. Apr 2022
  81. aacrjournals.org aacrjournals.org
    Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models
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    aacrjournals.org/mct/article/20/12/2352/675163/Rational-Combination-of-CRM1-Inhibitor-Selinexor
  82. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    sciencedirect.com/science/article/pii/S2211124722003886
  83. Jan 2022
  84. link.springer.com link.springer.com
    Sequential azacitidine and carboplatin induces immune activation in platinum-resistant high-grade serous ovarian cancer cell lines and primes for checkpoint inhibitor immunotherapy
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    link.springer.com/article/10.1186/s12885-022-09197-w
  85. Sep 2021
  86. www.sciencedirect.com www.sciencedirect.com
    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
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    sciencedirect.com/science/article/pii/S2211124721010755
  87. Aug 2021
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6251623/
  89. Oct 2020
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  91. Sep 2020
  92. www.thno.org www.thno.org
    WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer
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    thno.org/v10p0537.htm
  93. www.mdpi.com www.mdpi.com
    Metabolism of Estrogens: Turnover Differs Between Platinum-Sensitive and -Resistant High-Grade Serous Ovarian Cancer Cells
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    mdpi.com/2072-6694/12/2/279
  94. www.sciencedirect.com www.sciencedirect.com
    The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells
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    sciencedirect.com/science/article/pii/S1535610820300428
  95. www.sciencedirect.com www.sciencedirect.com
    A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets
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    sciencedirect.com/science/article/pii/S2211124720310056
  96. Jan 2020
  97. www.sciencedirect.com www.sciencedirect.com
    Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles
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    sciencedirect.com/science/article/pii/S2211124719303109