Hypothesis

22 Matching Annotations

Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer

1
1. scibot 14 Jan 2026
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/2159-8290.CD-25-0605
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12793832/
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An Acrolein-Based Drug Delivery System Enables Tumor-Specific Sphingosine-1-Phosphate Targeting in Breast Cancer without Lymphocytopenia

1
1. scibot 25 Jun 2025
  
  in Public
  
  CVCL_1400
  
  DOI: 10.1158/2767-9764.CRC-25-0023
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12174973/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety

1
1. scibot 11 Mar 2025
  
  in Public
  
  ATCCHTB-25
  
  DOI: 10.1016/j.ccell.2025.02.006
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825000583
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling

1
1. scibot 12 Sep 2024
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1002/cti2.1524
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11378723/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes

1
1. scibot 03 Jul 2024
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.3389/fonc.2024.1403052
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC11190739/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA

1
1. scibot 05 Jan 2024
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1038/s41467-023-44376-8
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10761696/
Nov 2023
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Adavosertib Enhances Antitumor Activity of Trastuzumab Deruxtecan in HER2-Expressing Cancers

1
1. scibot 03 Nov 2023
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/1078-0432.CCR-23-0103
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

pubmed.ncbi.nlm.nih.gov/37279095/
Oct 2023
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

1
1. scibot 07 Oct 2023
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/1078-0432.ccr-23-0103
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

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52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Aug 2023
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

1
1. scibot 11 Aug 2023
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/1078-0432.ccr-23-0103
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Jul 2023
52.53.155.43 52.53.155.43

ccr-23-0103-html.html

1
1. scibot 08 Jul 2023
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/1078-0432.ccr-23-0103
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

52.53.155.43/05abf3a0903b8473a428373dc7a2f791e1da90bb/ccr-23-0103-html.html
Jun 2022
aacrjournals.org aacrjournals.org

Zenocutuzumab, a HER2xHER3 bispecific antibody, is effective therapy for tumors driven by NRG1 gene rearrangements

1
1. scibot 01 Jun 2022
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/2159-8290.CD-21-1119
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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URL

aacrjournals.org/cancerdiscovery/article/12/5/1233/694554/Zenocutuzumab-a-HER2xHER3-Bispecific-Antibody-Is
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The anti-HER3 monoclonal antibody seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with oncogenic NRG1 fusions

1
1. scibot 02 Dec 2021
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/1078-0432.CCR-20-3605
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8172458/
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 01 Aug 2021
  
  in Public
  
  CVCL_1400
  
  DOI: 10.1016/j.cels.2019.11.001
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400 RRIDCUR:Validated
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RRID:CVCL_1400

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2405471219303874
May 2021
link.springer.com link.springer.com

Effect of Wnt5a on drug resistance in estrogen receptor-positive breast cancer

1
1. scibot 29 May 2021
  
  in Public
  
  CVCL_1400
  
  DOI: 10.1007/s12282-021-01241-0
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

link.springer.com/article/10.1007/s12282-021-01241-0
www.sciencedirect.com www.sciencedirect.com

Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
  in Public
  
  HTB-25
  
  DOI: 10.1016/j.cels.2021.04.002
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1400
  
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  RRID:CVCL_1400 RRIDCUR:Missing
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RRID:CVCL_1400

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2405471221001113
Oct 2020
www.cell.com www.cell.com

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

1
1. scibot 18 Oct 2020
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1016/j.chembiol.2020.07.011
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1400
  
  What is this?
  
  RRID:CVCL_1400 RRIDCUR:Validated
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RRID:CVCL_1400

RRIDCUR:Validated

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scibot

URL

cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity

1
1. scibot 30 Sep 2020
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1016/j.ebiom.2020.102996
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1400
  
  What is this?
  
  RRID:CVCL_1400 RRIDCUR:Validated
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RRID:CVCL_1400

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7501074/
mct.aacrjournals.org mct.aacrjournals.org

ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers

1
1. scibot 11 Sep 2020
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1158/1535-7163.MCT-19-1004
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1400
  
  Curator comments: MDA-MB-175-VII cell line ATCC Cat# HTB-25
  
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  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

mct.aacrjournals.org/content/19/9/1833
onlinelibrary.wiley.com onlinelibrary.wiley.com

FGF13 promotes metastasis of triple‐negative breast cancer

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1002/ijc.32874
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1400
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1400
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RRID:CVCL_1400

RRIDCUR:Validated

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.32874
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1016/j.celrep.2019.08.105
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1400
  
  What is this?
  
  RRID:CVCL_1400 RRIDCUR:Validated
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RRID:CVCL_1400

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719311672
www.sciencedirect.com www.sciencedirect.com

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1400
  
  DOI: 10.1016/j.cmet.2019.01.020
  
  Resource: (ATCC Cat# HTB-25, RRID:CVCL_1400)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1400
  
  What is this?
  
  RRID:CVCL_1400 RRIDCUR:Validated
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RRID:CVCL_1400

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1550413119300208
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1400
  
  Resource used:
  
  (NCBI_Iran Cat# C432, RRID:CVCL_1400)
  
  SciCrunch record: RRID:CVCL_1400
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1400
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RRID:CVCL_1400

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818301740