Hypothesis

18 Matching Annotations

Jul 2026
www.sciencedirect.com www.sciencedirect.com

A structure-based modeling approach identifies effective drug combinations for RAS-mutant acute myeloid leukemia

1
1. scibot 21 Jul 2026
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.isci.2026.116875
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

sciencedirect.com/science/article/pii/S2589004226022534
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting BMP and TAZ/TEAD mechanotransduction pathways impairs acute myeloid leukemia chemoresistance

1
1. scibot 06 Jun 2026
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1038/s41375-026-02904-7
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13233328/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies

1
1. scibot 18 Dec 2024
  
  in Public
  
  RRID: CVCL_1418
  
  DOI: 10.1016/j.cell.2024.11.007
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424013242
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15

2
1. scibot 29 Sep 2023
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.isci.2023.107844
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
2. scibot 29 Sep 2023
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.isci.2023.107844
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
www.sciencedirect.com www.sciencedirect.com

PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy

1
1. scibot 08 Sep 2023
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.xcrm.2023.101191
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123003580
Jan 2023
www.sciencedirect.com www.sciencedirect.com

METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

1
1. scibot 06 Jan 2023
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.stem.2022.12.006
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

sciencedirect.com/science/article/pii/S1934590922004908
May 2022
www.sciencedirect.com www.sciencedirect.com

Antigen presentation safeguards the integrity of the hematopoietic stem cell pool

1
1. scibot 06 May 2022
  
  in Public
  
  DSMZACC 15
  
  DOI: 10.1016/j.stem.2022.04.007
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

sciencedirect.com/science/article/pii/S1934590922001606
Mar 2022
www.sciencedirect.com www.sciencedirect.com

The proteogenomic subtypes of acute myeloid leukemia

1
1. scibot 04 Mar 2022
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.ccell.2022.02.006
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

sciencedirect.com/science/article/pii/S1535610822000587
Jan 2022
www.sciencedirect.com www.sciencedirect.com

SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia

1
1. scibot 12 Jan 2022
  
  in Public
  
  ACC 15
  
  DOI: 10.1016/j.celrep.2021.110233
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721017423
Aug 2021
elifesciences.org elifesciences.org

HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

1
1. scibot 15 Aug 2021
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.7554/eLife.64148
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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RRID:CVCL_1418

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scibot

URL

elifesciences.org/articles/64148
www.sciencedirect.com www.sciencedirect.com

ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

1
1. scibot 07 Aug 2021
  
  in Public
  
  ACC-15
  
  DOI: 10.1016/j.molcel.2021.07.018
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1418

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521005876
Jul 2021
www.sciencedirect.com www.sciencedirect.com

A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia

1
1. scibot 31 Jul 2021
  
  in Public
  
  Human: ML2
  
  DOI: 10.1016/j.ccell.2019.11.001
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1418

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819305215
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion

1
1. scibot 17 Apr 2021
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.ccell.2020.04.017
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418
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Tags

RRID:CVCL_1418

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820302166
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Vitamin B6 Addiction in Acute Myeloid Leukemia

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.ccell.2019.12.002
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1418
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RRIDCUR:Validated

RRID:CVCL_1418

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819305720
Jan 2020
www.sciencedirect.com www.sciencedirect.com

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:CVCL_1418
  
  DOI: 10.1016/j.ccell.2018.10.004
  
  Resource: (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:CVCL_1418
  
  What is this?
  
  RRID:CVCL_1418 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_1418

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818304707
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  ACC 15
  
  Curator: @Jmenke
  
  Resource used:
  
  (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  SciCrunch record: RRID:CVCL_1418
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1418 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:CVCL_1418

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610817303641
www.sciencedirect.com www.sciencedirect.com

Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  ML-2
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (DSMZ Cat# ACC-15, RRID:CVCL_1418)
  
  SciCrunch record: RRID:CVCL_1418
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1418 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:CVCL_1418

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867416316853