Hypothesis

14 Matching Annotations

Jul 2025
www.sciencedirect.com www.sciencedirect.com

KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.1016/j.ccell.2025.06.011
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1478
  
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  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825002612
Mar 2025
www.sciencedirect.com www.sciencedirect.com

CDK4 selective inhibition improves preclinical anti-tumor efficacy and safety

1
1. scibot 11 Mar 2025
  
  in Public
  
  ATCCCRL-5877
  
  DOI: 10.1016/j.ccell.2025.02.006
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825000583
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids

1
1. scibot 05 Sep 2024
  
  in Public
  
  RRID: CVCL_1478
  
  DOI: 10.1158/1078-0432.CCR-23-3980
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @vtello
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11369614/
May 2024
www.sciencedirect.com www.sciencedirect.com

Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations

1
1. scibot 23 May 2024
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.1016/j.xcrm.2024.101578
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

sciencedirect.com/science/article/pii/S2666379124002702
Nov 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

1
1. scibot 12 Nov 2023
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.1002/ijc.34783
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.34783
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Smoking-associated Downregulation of FILIP1L Enhances Lung Adenocarcinoma Progression Through Mucin Production, Inflammation, and Fibrosis

1
1. scibot 05 Mar 2023
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.1158/2767-9764.CRC-22-0233
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9973389/
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes

1
1. scibot 14 Apr 2022
  
  in Public
  
  CVCL_1478
  
  DOI: 10.1016/j.celrep.2022.110636
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722003886
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma

1
1. scibot 30 Jul 2021
  
  in Public
  
  H1573
  
  DOI: 10.1016/j.ccell.2019.07.002
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1478

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scibot

URL

sciencedirect.com/science/article/pii/S1535610819303290
mcr.aacrjournals.org mcr.aacrjournals.org

An IFNγ/STAT1/JMJD3 Axis Induces ZEB1 Expression and Promotes Aggressiveness in Lung Adenocarcinoma

1
1. scibot 14 Jul 2021
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.1158/1541-7786.MCR-20-0948
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

mcr.aacrjournals.org/content/19/7/1234
Jun 2021
elifesciences.org elifesciences.org

A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma

1
1. scibot 29 Jun 2021
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.7554/eLife.65234
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478
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RRID:CVCL_1478

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scibot

URL

elifesciences.org/articles/65234
Sep 2020
elifesciences.org elifesciences.org

Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

1
1. scibot 13 Sep 2020
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.7554/eLife.53367
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1478
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RRID:CVCL_1478

RRIDCUR:Validated

Annotators

scibot

URL

elifesciences.org/articles/53367
www.sciencedirect.com www.sciencedirect.com

A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers

1
1. scibot 11 Sep 2020
  
  in Public
  
  RRID:CVCL_1478
  
  DOI: 10.1016/j.ccell.2020.03.004
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1478
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RRID:CVCL_1478

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610820301057
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 03 Sep 2020
  
  in Public
  
  CVCL_1478
  
  DOI: 10.1002/1878-0261.12600
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_1478

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scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12600
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_1478
  
  DOI: 10.1016/j.cmet.2019.11.012
  
  Resource: (ATCC Cat# CRL-5877, RRID:CVCL_1478)
  
  Curator: @ethanbadger
  
  SciCrunch record: CVCL_1478
  
  What is this?
  
  RRID:CVCL_1478 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_1478

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119306199