232 Matching Annotations
  1. Sep 2026
  2. www.sciencedirect.com www.sciencedirect.com
    Fast tumor accumulation and payload release of c-Met targeting aptamer-drug conjugate enables robust anti-tumor efficacy
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    sciencedirect.com/science/article/pii/S2666379126004222
  3. Aug 2026
  4. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Abietane-Type Diterpenoids From Salvia kiangsiensis: Isolation, Semisynthesis, and Cytotoxicity of Their Oxime Ester Derivatives
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    onlinelibrary.wiley.com/doi/10.1002/cbdv.71589
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JI017 Sensitizes EGFR-T790M NSCLC to Erlotinib by Extinguishing the STAT3–Survivin Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13438235/
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CCL20 Released by Drug–Tolerant Persisters Impairs Immunotherapy in <i>EGFR–</i>Mutant Lung Adenocarcinoma
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    onlinelibrary.wiley.com/doi/10.1002/mco2.70888
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    Mycoplasma infection drives EGFR-TKI resistance through convergent transcriptomic reprogramming in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S2589004226023771
  8. Jul 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of XNW5004 as a novel EZH2 inhibitor that enhances anti-tumor immunity and synergizes with PD-1 blockade immunotherapy in lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13410854/
  10. 54.241.53.176 54.241.53.176
    2026.07.19.735925v1.full-html.html
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    54.241.53.176/09edf509d6d686dd88c31fa6438ce9ded1c7be65/2026.07.19.735925v1.full-html.html
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KRAS-mediated CCDC6 degradation drives xCT upregulation and ferroptosis evasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13369686/
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    Pemetrexed potentiates γδ T cell-based immunotherapy in NSCLC through ATM-STING-NF-κB-mediated induction of NKG2D ligands
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    sciencedirect.com/science/article/pii/S1567576926009616
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    Repurposed ethoxzolamide reprograms antitumor immunity through β-TrCP-dependent PD-L1 ubiquitination
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    sciencedirect.com/science/article/pii/S266637912600337X
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    Extracellular vesicles derived from cancer-associated fibroblasts facilitate NSCLC progression and metastasis via miR-664b-5p-mediated activation of the CXCL12/CXCR4 chemokine pathway
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    sciencedirect.com/science/article/pii/S0925443926002231
  15. 54.241.53.176 54.241.53.176
    MTFR2 promotes VDAC1 oligomerization to reprogram BCAA metabolism in tumor cells to polarize TAMs in LUAD
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    54.241.53.176/05086ace4c7a9d30ef1a5082d0bfcf0e99f62e65/s41419-026-08871-2_reference-html.html
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unbiased avidity-based isolation of antigen-specific T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13347823/
  17. 54.241.53.176 54.241.53.176
    Mitochondrial translocation of MDM2 and TFAM reprograms metabolism in treatment-refractory cancers
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    54.241.53.176/b2ad43df4b0cad196082fde33923416f2cb86ae8/s41698-025-01257-1_reference-html.html
  18. Jun 2026
  19. www.mdpi.com www.mdpi.com
    Establishment of a Flow Cytometry Protocol for Binarily Detecting Circulating Tumor Cells with EGFR Mutation
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    mdpi.com/2079-9721/13/12/406
  20. www.sciencedirect.com www.sciencedirect.com
    Targeting TROP2 in drug-tolerant persister cells delays EGFR tyrosine kinase inhibitor resistance in non-small-cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610826002655
  21. aacrjournals.org aacrjournals.org
    The activity of EGFR CAR-NK and CAR-T cells against EGFR inhibitor-resistant NSCLC and drug-tolerant persister cells
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    aacrjournals.org/clincancerres/article/31/22/4745/767041/The-Activity-of-EGFR-CAR-NK-and-CAR-T-Cells
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    Effect of isoginkgetin on targeting methylenetetrahydrofolate dehydrogenase 2 to induce ROS-mediated apoptosis in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0944711326006562
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    Hypoxia-activated PROTAC for dual inhibition of FAK and EGFR enables synergistic mechano-chemical cancer therapy
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    sciencedirect.com/science/article/pii/S1476558626000588
  24. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76039
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13131504/
  26. May 2026
  27. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70264
  28. www.sciencedirect.com www.sciencedirect.com
    Gasdermin C reprograms metabolism through the CAMKK2-AMPK axis to promote lung adenocarcinoma progression and radioresistance
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    sciencedirect.com/science/article/pii/S221112472600505X
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Extracellular matrix-driven patient stratification and network modeling reveal distinct molecular grades with potential clinical implications
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    pmc.ncbi.nlm.nih.gov/articles/PMC13168567/
  30. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70490
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GFAT2-mediated HSPD1 O-GlcNAcylation drives chemotherapy resistance in non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13141267/
  32. aacrjournals.org aacrjournals.org
    Constitutive EGFR activation induced by PTPRR downregulation confers resistance to KRAS inhibitors
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    aacrjournals.org/cancerrescommun/article/6/4/728/781786/Constitutive-EGFR-Activation-Induced-by-PTPRR
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JIN-A02, a Mutant-Selective Fourth-Generation EGFR inhibitor, Overcomes C797S-Mediated Resistance and Demonstrates Intracranial Activity in NSCLC
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133602/
  34. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R-Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202521238
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired resistance to the PRMT5 inhibitor confers collateral sensitivity to MEK inhibition in MTAP-null non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13131504/
  36. Apr 2026
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FOXM1-specific TCR-engineered T cells target non-small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13119620/
  38. www.sciencedirect.com www.sciencedirect.com
    IGF2R as a master regulator of acquired EGFR inhibitor resistance and therapeutic target in non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S014181302602146X
  39. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A covalent molecular glue hijacks the E3 ligase MKRN2 to degrade the ribosomal protein RPS7 and induce synthetic lethality in p53-deficient NSCLC cells
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70434
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Base Editing of TIGIT Reprograms CD155 Signaling in Natural Killer Cells to Enhance Cancer Immunotherapy Efficacy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13080321/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
  42. link.springer.com link.springer.com
    HIF-1α siRNA Enhances the Efficacy of Erlotinib in Non-small Cell Lung Cancer: A Novel Strategy to Reverse Hypoxia-Induced Drug Resistance
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    link.springer.com/article/10.1007/s40268-025-00534-5
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitofusin-2 suppresses tumor immune escape through EGFR/STAT3-mediated PD-L1 transcription
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    pmc.ncbi.nlm.nih.gov/articles/PMC13039860/
  44. Mar 2026
  45. link.springer.com link.springer.com
    CCNB2, NUSAP1, GTSE1, and TK1: potential dual biomarkers for pneumonia and lung adenocarcinoma
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    link.springer.com/article/10.1007/s10616-026-00940-w
  46. www.sciencedirect.com www.sciencedirect.com
    UFMylation-dependent inhibition of AKT signaling by PHLDA3 in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124726002329
  47. pubs.acs.org pubs.acs.org
    EXAGO: An Argonaute-Based Primer-Free Exponential Amplification Strategy for Ultrasensitive Zero-Background Detection of Point Mutation
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    pubs.acs.org/doi/10.1021/acs.analchem.5c06961
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The STAT3–ZEB1 axis contributes to CCL2-mediated resistance to osimertinib in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12962936/
  49. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202522996
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sym024 interacts with a unique epitope on the CD73 homodimer, favoring effective bivalent binding to improve anti-PD1 therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950896/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aspartate availability drives differential engagement of the malate-aspartate shuttle
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    pmc.ncbi.nlm.nih.gov/articles/PMC12952686/
  52. Feb 2026
  53. www.sciencedirect.com www.sciencedirect.com
    SQSTM1/p62-mediated PD-L1 biomolecular condensate formation promotes lung tumorigenesis
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    sciencedirect.com/science/article/pii/S2090123226001785
  54. spj.science.org spj.science.org
    Tumor Exosomal L1 Cell Adhesion Molecule Promotes Brain Metastasis of Lung Cancer
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    spj.science.org/doi/10.34133/research.1126
  55. www.nature.com www.nature.com
    High-throughput identification of endogenous biomolecular condensates and phase-separating proteins
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    nature.com/articles/s41596-025-01327-5
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor Exosomal L1 Cell Adhesion Molecule Promotes Brain Metastasis of Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12886715/
  57. www.sciencedirect.com www.sciencedirect.com
    PARP inhibitor combined with platinum activates the cGAS-STING pathway to enhance anti-PD-L1 immunotherapy in lung adenocarcinoma
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    sciencedirect.com/science/article/pii/S1567576926001694
  58. Jan 2026
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SERPINB3 enhances NPM1 sumoylation via inhibiting SENP3’s activity and promotes lung tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12847774/
  60. www.sciencedirect.com www.sciencedirect.com
    Dual targeting of SLC25A51 and succinate dehydrogenase selectively depletes mitochondrial NAD+ to eradicate KRAS-driven AML
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    sciencedirect.com/science/article/pii/S155041312600001X
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A combined strategy of EGFR-MET bispecific antibody and HER3 ADC to overcome osimertinib resistance in NSCLC
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    pmc.ncbi.nlm.nih.gov/articles/PMC12847129/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Profiling of Extracellular Vesicles of Non‐Small Cell Lung Cancer Reveals Proteins Associated With Osimertinib Resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12832073/
  63. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202511408
  64. www.sciencedirect.com www.sciencedirect.com
    ANP32A-mediated Histone 3 K27 Acetylation is Essential for Sotorasib Activity in KRAS-mutant Non-Small Cell Lung Cancer
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    sciencedirect.com/science/article/pii/S002192582502962X
  65. www.sciencedirect.com www.sciencedirect.com
    Mitigating tumor heterogeneity in lung Cancer: A dual-targeted NIR-II imaging strategy for accurate tumor localization and intraoperative navigation
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    sciencedirect.com/science/article/pii/S0304383526000042
  66. Dec 2025
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sappanchalcone Suppresses NSCLC by Oxidative Stress-Driven DNA Damage and ER Stress Activation through PIEZO1 Modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12702247/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical pharmacokinetic, pharmacodynamic, and safety profile of OBI-992: a novel TROP2-targeted antibody–drug conjugate
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670072/
  69. Nov 2025
  70. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy
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    sciencedirect.com:5037/science/article/pii/S0006295225008275
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DUSP11 is an intracellular innate immune checkpoint in lung adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12642826/
  72. 54.241.53.176 54.241.53.176
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70220
  74. www.sciencedirect.com www.sciencedirect.com
    Anti-NSCLC efficacy of a novel ROR1/PI3Kα/BRD4 multi-target inhibitor
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    sciencedirect.com/science/article/pii/S0968089625004249
  75. Oct 2025
  76. www.sciencedirect.com www.sciencedirect.com
    Induction of a metabolic switch from glucose to ketone metabolism programs ketogenic diet-induced therapeutic vulnerability in lung cancer
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    sciencedirect.com/science/article/pii/S1550413125004358
  77. www.biorxiv.org www.biorxiv.org
    Co-targeting MERTK and EGFR with a Bispecific Antibody Overcomes Drug Resistance Across Mutations in Exons 19, 20, and 21
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    biorxiv.org/content/10.1101/2025.10.16.681972v1
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    tRF3a-MetCAT Promotes EGFR-Targeted Therapeutic Resistance through the TRIM21–STAT1–C5a Axis in Lung Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12501432/
  79. www.sciencedirect.com www.sciencedirect.com
    Optimized arenaviruses with tumor-tropic mutations promote safe anti-tumor efficacy via sustainable immune modulatory properties
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    sciencedirect.com/science/article/pii/S2666379125004847
  80. www.sciencedirect.com www.sciencedirect.com
    A cancer-specific antigen drives histone acetylation by stabilizing the acetyltransferases
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    sciencedirect.com/science/article/pii/S2211124725011799
  81. Sep 2025
  82. www.sciencedirect.com www.sciencedirect.com
    Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens
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    sciencedirect.com/science/article/pii/S0092867425010323
  83. 52.53.155.43 52.53.155.43
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  84. www.biorxiv.org www.biorxiv.org
    Extracellular Matrix-Guided Tumor Stratification and Network Models Reveal Clinical Molecular Grades
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    biorxiv.org/content/10.1101/2025.08.29.672994v1
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Notch3 mediated TGF-β1 activation enhances epithelial-mesenchymal transition and cancer stemness in non-small lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12370359/
  86. Aug 2025
  87. www.science.org www.science.org
    Diverse oncogenes use common mechanisms to drive growth of major forms of human cancer
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    science.org/doi/10.1126/sciadv.adt1798
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.70238
  89. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    EGFR Targeted Liposomal PROTAC Assisted With Epigenetic Regulation as an Efficient Strategy for Osimertinib-Resistant Lung Cancer Therapy
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202510197
  90. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    HACD3 promotes malignant progression of NSCLC by suppressing the MKK7/MAPK10 signaling axis
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    bmccancer.biomedcentral.com/articles/10.1186/s12885-025-14621-y
  91. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical Evaluation of DB-1419, a Novel Bifunctional and Bispecific Anti–B7-H3 × PD-L1 Antibody–Drug Conjugate
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    pmc.ncbi.nlm.nih.gov/articles/PMC12351279/
  92. www.sciencedirect.com www.sciencedirect.com
    Dapk2 dysfunction leads to Mic60 lactylation and mitochondrial metabolic reprogramming, promoting lung cancer EGFR-TKI resistance and metastasis
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    sciencedirect.com/science/article/pii/S153458072500471X
  93. www.nature.com www.nature.com
    NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers
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    nature.com/articles/s41586-025-09299-y
  94. www.sciencedirect.com www.sciencedirect.com
    Integrative analysis of lung adenocarcinoma across diverse ethnicities and exposures
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  201. Apr 2023
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  204. Mar 2023
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  206. Jan 2023
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  211. Oct 2022
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  213. Sep 2022
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  226. Apr 2022
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  234. Jan 2022
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  236. Nov 2021
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  240. Oct 2021
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  242. Sep 2021
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  244. Aug 2021
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  252. Jul 2021
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    miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer
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