Hypothesis

21 Matching Annotations

Last 7 days
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Macropinocytosis and Vascularization Determine Response to mTOR Inhibitors in Lung Squamous Cell Carcinoma

1
1. scibot 08 Apr 2026
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1158/0008-5472.CAN-25-0921
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12774322/
www.nature.com www.nature.com

AXL–SHC1 signaling axis mediates adaptive resistance to HER2-targeted tyrosine kinase inhibitors in HER2-aberrant lung and gastric cancers

1
1. scibot 07 Apr 2026
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1038/s41698-026-01385-2
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

nature.com/articles/s41698-026-01385-2
Mar 2026
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

E2A selectively regulates TGF-β–induced apoptosis in KRAS-mutant non-small cell lung cancer

1
1. scibot 31 Mar 2026
  
  in Public
  
  CVCL_1535
  
  DOI: 10.1002/1878-0261.70236
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70236
www.sciencedirect.com www.sciencedirect.com

Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature

1
1. scibot 26 Mar 2026
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1016/j.xcrm.2026.102694
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379126001114
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Aspartate availability drives differential engagement of the malate-aspartate shuttle

1
1. scibot 04 Mar 2026
  
  in Public
  
  ATCC Cat#CRL-5928
  
  DOI: 10.1016/j.molcel.2026.02.004
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12952686/
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer

1
1. scibot 14 Jan 2026
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1158/2159-8290.CD-25-0605
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12793832/
Aug 2025
bmccancer.biomedcentral.com bmccancer.biomedcentral.com

HACD3 promotes malignant progression of NSCLC by suppressing the MKK7/MAPK10 signaling axis

1
1. scibot 19 Aug 2025
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1186/s12885-025-14621-y
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

bmccancer.biomedcentral.com/articles/10.1186/s12885-025-14621-y
Jul 2025
www.sciencedirect.com www.sciencedirect.com

KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

1
1. scibot 15 Jul 2025
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1016/j.ccell.2025.06.011
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610825002612
May 2025
www.sciencedirect.com www.sciencedirect.com

MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer

1
1. scibot 20 May 2025
  
  in Public
  
  ATCCCat# CRL-5928
  
  DOI: 10.1016/j.celrep.2025.115722
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725004930
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting AKR1B10 by drug repurposing with epalrestat overcomes chemoresistance in non-small cell lung cancer patient-derived tumor organoids

1
1. scibot 05 Sep 2024
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1158/1078-0432.CCR-23-3980
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11369614/
Jul 2024
www.cell.com www.cell.com

Pan-cancer proteogenomics expands the landscape of therapeutic targets

1
1. scibot 24 Jul 2024
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1016/j.cell.2024.05.039
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

cell.com/cell/fulltext/S0092-8674(24)00583-X
Jan 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling

1
1. scibot 25 Jan 2024
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1002/1878-0261.13554
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
Oct 2023
aacrjournals.org aacrjournals.org

MTX-13, a novel PTK7-directed antibody-drug conjugate with widened therapeutic index shows sustained tumor regressions for a broader spectrum of PTK7-positive tumors

1
1. scibot 06 Oct 2023
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1158/1535-7163.MCT-23-0164
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

aacrjournals.org/mct/article/22/10/1128/729312/MTX-13-a-Novel-PTK7-Directed-Antibody-Drug
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors

1
1. scibot 29 Jul 2023
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1016/j.isci.2023.107302
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2589004223013792
52.53.155.43 52.53.155.43

mct-23-0164-html.html

1
1. scibot 13 Jul 2023
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1158/1535-7163.mct-23-0164
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

52.53.155.43/01b1bb0ac396a31d548b96b877ce7cde2b859b6a/mct-23-0164-html.html
Jul 2021
link.springer.com link.springer.com

miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer

1
1. scibot 31 Jul 2021
  
  in Public
  
  NCI-H2170
  
  DOI: 10.1186/s12885-019-6416-4
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:CVCL_1535

RRIDCUR:Missing

Annotators

scibot

URL

link.springer.com/article/10.1186/s12885-019-6416-4
Sep 2020
www.sciencedirect.com www.sciencedirect.com

The Negative Cross-Talk between SAG/RBX2/ROC2 and APC/C E3 Ligases in Regulation of Cell Cycle Progression and Drug Resistance

1
1. scibot 10 Sep 2020
  
  in Public
  
  H2170
  
  DOI: 10.1016/j.celrep.2020.108102
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1535
  
  Curator comments: NCI-H2170 cell line ATCC Cat# CRL-5928
  
  What is this?
  
  RRID:CVCL_1535 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:CVCL_1535

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720310913
www.sciencedirect.com www.sciencedirect.com

Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:CVCL_1535
  
  DOI: 10.1016/j.celrep.2019.12.071
  
  Resource: (BCRJ Cat# 0271, RRID:CVCL_1535)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1535
  
  What is this?
  
  RRID:CVCL_1535 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_1535

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719317280
Nov 2018
www.sciencedirect.com www.sciencedirect.com

UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL-5928
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-5928, RRID:CVCL_1535)
  
  SciCrunch record: RRID:CVCL_1535
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1535 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:CVCL_1535

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276518304441
www.sciencedirect.com www.sciencedirect.com

The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1535
  
  Resource used:
  
  (ATCC Cat# CRL-5928, RRID:CVCL_1535)
  
  SciCrunch record: RRID:CVCL_1535
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818301739
www.sciencedirect.com www.sciencedirect.com

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1535
  
  Resource used:
  
  (ATCC Cat# CRL-5928, RRID:CVCL_1535)
  
  SciCrunch record: RRID:CVCL_1535
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1535
Visit annotations in context

Tags

RRID:CVCL_1535

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867417312448