75 Matching Annotations
  1. Aug 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Smoking carcinogen induced inflammation promotes lung carcinogenesis via IRAK4 activation
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11832316/
  3. www.sciencedirect.com www.sciencedirect.com
    USP8 deubiquitylation-boosted NSUN4 potentiates lung squamous cell carcinoma progression by m5C methylation of DHCR24
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725009295
  4. www.sciencedirect.com www.sciencedirect.com
    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610825003101
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FBXW5 Promotes Epithelial-Mesenchymal Transition in Lung Adenocarcinoma Through the KLF13/TROAP Signaling Pathway
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/full/10.1002/mc.70018
  6. Jul 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11695159/
  8. Jun 2025
  9. 52.53.155.43 52.53.155.43
    1-s2.0-S258900422501226X-main-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/d1f78810f1eafd7cac950f9c8a5713f79fe4d700/1-s2.0-S258900422501226X-main-html.html
  10. cancer-nano.biomedcentral.com cancer-nano.biomedcentral.com
    Exosomal encapsulation of a steviol derivative SD9 to overcome TRAIL resistance as a highly effective therapy against lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    cancer-nano.biomedcentral.com/articles/10.1186/s12645-025-00329-y
  11. 52.53.155.43 52.53.155.43
    PDF-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/9a2f79631a0beb40aa09f744c00e5a575573d112/PDF-html.html
  12. May 2025
  13. www.sciencedirect.com www.sciencedirect.com
    MYC plus class IIa HDAC inhibition drives mitochondrial dysfunction in non-small cell lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725004930
  14. Mar 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11911804/
  16. Feb 2025
  17. www.sciencedirect.com www.sciencedirect.com
    TGF-β1-mediated intercellular signaling fuels cooperative cellular invasion
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124725000865
  18. aacrjournals.org aacrjournals.org
    TGF-β antagonizes IFN-γ-mediated adaptive immune evasion via activation of the AKT-Smad3-SHP1 axis in lung adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    aacrjournals.org/cancerres/article/83/13/2262/727433/TGF-Antagonizes-IFN-Mediated-Adaptive-Immune
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Selective WEE1 Inhibitor Azenosertib Shows Synergistic Antitumor Activity with KRASG12C Inhibitors in Preclinical Models
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11795354/
  20. Jan 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11668523/
  22. Dec 2024
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Imaging NRF2 activation in non-small cell lung cancer with positron emission tomography
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pmc.ncbi.nlm.nih.gov/articles/PMC11652680/
  24. Sep 2024
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FHL2 expression by cancer-associated fibroblasts promotes metastasis and angiogenesis in lung adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1002/ijc.35174
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A common druggable signature of oncogenic c-Myc, mutant KRAS and mutant p53 reveals functional redundancy and competition among oncogenes in cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11365971/
  27. Aug 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11292194/
  29. Jul 2024
  30. iubmb.onlinelibrary.wiley.com iubmb.onlinelibrary.wiley.com
    The flavonoid quercetin decreases ACE2 and TMPRSS2 expression but not SARS-CoV-2 infection in cultured human lung cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.2084
  31. May 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2666379124002702
  33. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276524003241
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  35. Apr 2024
  36. www.sciencedirect.com www.sciencedirect.com
    NECTIN2 is a prognostic biomarker and potential therapeutic target in lung adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2212534524000558
  37. Mar 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945624000874
  39. Feb 2024
  40. www.biorxiv.org www.biorxiv.org
    A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2023.12.20.572548v1
  41. Jan 2024
  42. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simplified Synthesis of Renieramycin T Derivatives to Target Cancer Stem Cells via β-Catenin Proteasomal Degradation in Human Lung Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10744608/
  44. Dec 2023
  45. www.sciencedirect.com www.sciencedirect.com
    G-quadruplex is critical to epigenetic activation of the lncRNA HOTAIR in cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004223026366
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATM mutations associate with distinct co-mutational patterns and therapeutic vulnerabilities in NSCLC
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10690143/
  47. 52.53.155.43 52.53.155.43
    ccr-23-1122-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/6e7bec526fc86dd5978cecd27d77cfeec2624a0c/ccr-23-1122-html.html
  48. Nov 2023
  49. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  50. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13505
  51. www.sciencedirect.com www.sciencedirect.com
    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1074761323004181
  52. Oct 2023
  53. 52.53.155.43 52.53.155.43
    ccr-23-1122-html.html
    2
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/6e7bec526fc86dd5978cecd27d77cfeec2624a0c/ccr-23-1122-html.html
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Ascorbate Elicits Anti-Cancer Activities against Non-Small Cell Lung Cancer through Hydrogen-Peroxide-Induced-DNA-Damage
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10525775/
  55. Sep 2023
  56. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Horie-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/b5e8e877c627d157950951119edc64db79086ad6/Molecular Oncology - 2023 - Horie-html.html
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC10473160/
  58. Jul 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC9938728/
  60. www.nature.com www.nature.com
    MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    nature.com/articles/s41389-023-00478-y
  61. Jun 2023
  62. 52.53.155.43 52.53.155.43
    can-22-3009-html.html
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    52.53.155.43/23465825fc5c1614cd30949f4c30491df07cc998/can-22-3009-html.html
  63. www.sciencedirect.com www.sciencedirect.com
    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945623001551
  64. www.mdpi.com www.mdpi.com
    Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2073-4409/12/12/1627
  65. Sep 2022
  66. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722012694
  67. www.sciencedirect.com www.sciencedirect.com
    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610822003798
  68. May 2022
  69. www.sciencedirect.com www.sciencedirect.com
    ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276522004348
  70. Apr 2022
  71. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124722003886
  72. Mar 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  74. Nov 2021
  75. www.sciencedirect.com www.sciencedirect.com
    HNRNPA2B1 as a trigger of RNA switch modulates the miRNA-mediated regulation of CDK6
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2589004221013146
  76. Aug 2021
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
  78. Jul 2021
  79. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124719311520
  80. www.sciencedirect.com www.sciencedirect.com
    Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610819303290
  81. www.sciencedirect.com www.sciencedirect.com
    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867419306336
  82. www.sciencedirect.com www.sciencedirect.com
    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413119303171
  83. www.mdpi.com www.mdpi.com
    Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2218-273X/9/7/280/htm
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC8266391/
  85. Jun 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721006628
  87. May 2021
  88. www.sciencedirect.com www.sciencedirect.com
    3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276520306936
  89. Mar 2021
  90. www.sciencedirect.com www.sciencedirect.com
    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2211124721001224
  91. Sep 2020
  92. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pubmed.ncbi.nlm.nih.gov/32987811/
  93. www.mdpi.com www.mdpi.com
    Methylation Patterns and Chromatin Accessibility in Neuroendocrine Lung Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2072-6694/12/8/2003
  94. www.sciencedirect.com www.sciencedirect.com
    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610820301057
  95. www.mdpi.com www.mdpi.com
    Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    mdpi.com/2072-6694/12/4/875
  96. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    elifesciences.org/articles/53367
  97. www.sciencedirect.com www.sciencedirect.com
    KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610820301069
  98. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Identification and Target-Modification of SL-BBI: A Novel Bowman–Birk Type Trypsin Inhibitor from Sylvirana latouchii
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    pubmed.ncbi.nlm.nih.gov/32872343/
  99. Jan 2020
  100. www.sciencedirect.com www.sciencedirect.com
    Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1550413119306199
  101. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S2451945619300832
  102. www.sciencedirect.com www.sciencedirect.com
    MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1097276519301029
  103. Nov 2018
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC3566312/
  105. www.sciencedirect.com www.sciencedirect.com
    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610818303696
  106. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S0092867418300412
  107. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610818301831
  108. Nov 2017
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    ncbi.nlm.nih.gov/pmc/articles/PMC5345931/
  110. www.sciencedirect.com www.sciencedirect.com
    O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate
    1
    Visit annotations in context

    Tags

    Annotators

    URL

    sciencedirect.com/science/article/pii/S1535610817300624