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  1. Last 7 days
  2. iubmb.onlinelibrary.wiley.com iubmb.onlinelibrary.wiley.com
    The flavonoid quercetin decreases ACE2 and TMPRSS2 expression but not SARS-CoV-2 infection in cultured human lung cells
    1
    1. scibot 18 Jul 2024
      RRID:CVCL_1547

      DOI: 10.1002/biof.2084

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    iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.2084
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    1. scibot 23 May 2024
      RRID:CVCL_1547

      DOI: 10.1016/j.xcrm.2024.101578

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    sciencedirect.com/science/article/pii/S2666379124002702
  5. www.sciencedirect.com www.sciencedirect.com
    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
    1
    1. scibot 17 May 2024
      CRL-5800

      DOI: 10.1016/j.molcel.2024.04.009

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    sciencedirect.com/science/article/pii/S1097276524003241
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
    1
    1. scibot 17 May 2024
      RRID:CVCL_1547

      DOI: 10.1158/1078-0432.CCR-23-1763

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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  7. Apr 2024
  8. www.sciencedirect.com www.sciencedirect.com
    NECTIN2 is a prognostic biomarker and potential therapeutic target in lung adenocarcinoma
    1
    1. scibot 30 Apr 2024
      H23

      DOI: 10.1016/j.resinv.2024.04.002

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    sciencedirect.com/science/article/pii/S2212534524000558
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
    1
    1. scibot 29 Mar 2024
      Cat#CRL-5800

      DOI: 10.1016/j.chembiol.2024.02.013

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    sciencedirect.com/science/article/pii/S2451945624000874
  11. Feb 2024
  12. www.biorxiv.org www.biorxiv.org
    A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer
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    1. scibot 15 Feb 2024
      RRID:CVCL_1547

      DOI: 10.1101/2023.12.20.572548

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    biorxiv.org/content/10.1101/2023.12.20.572548v1
  13. Jan 2024
  14. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FBXL16 promotes cell growth and drug resistance in lung adenocarcinomas with KRAS mutation by stabilizing IRS1 and upregulating IRS1/AKT signaling
    1
    1. scibot 25 Jan 2024
      RRID:CVCL_1547

      DOI: 10.1002/1878-0261.13554

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13554
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simplified Synthesis of Renieramycin T Derivatives to Target Cancer Stem Cells via β-Catenin Proteasomal Degradation in Human Lung Cancer
    1
    1. scibot 17 Jan 2024
      CVCL_1547

      DOI: 10.3390/md21120627

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    ncbi.nlm.nih.gov/pmc/articles/PMC10744608/
  16. Dec 2023
  17. www.sciencedirect.com www.sciencedirect.com
    G-quadruplex is critical to epigenetic activation of the lncRNA HOTAIR in cancer cells
    1
    1. scibot 21 Dec 2023
      ATCCRRID: CVCL_1547

      DOI: 10.1016/j.isci.2023.108559

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    sciencedirect.com/science/article/pii/S2589004223026366
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATM mutations associate with distinct co-mutational patterns and therapeutic vulnerabilities in NSCLC
    1
    1. scibot 06 Dec 2023
      RRID:CVCL_1547

      DOI: 10.1158/1078-0432.CCR-23-1122

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    ncbi.nlm.nih.gov/pmc/articles/PMC10690143/
  19. 52.53.155.43 52.53.155.43
    ccr-23-1122-html.html
    1
    1. scibot 01 Dec 2023
      RRID:CVCL_1547

      DOI: 10.1158/1078-0432.ccr-23-1122

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    52.53.155.43/6e7bec526fc86dd5978cecd27d77cfeec2624a0c/ccr-23-1122-html.html
  20. Nov 2023
  21. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
    1
    1. scibot 12 Nov 2023
      RRID:CVCL_1547

      DOI: 10.1002/ijc.34783

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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  22. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
    1
    1. scibot 03 Nov 2023
      RRID:CVCL_1547

      DOI: 10.1002/1878-0261.13505

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13505
  23. www.sciencedirect.com www.sciencedirect.com
    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
    1
    1. scibot 02 Nov 2023
      RRID:CVCL_1547

      DOI: 10.1016/j.immuni.2023.09.013

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    sciencedirect.com/science/article/pii/S1074761323004181
  24. Oct 2023
  25. 52.53.155.43 52.53.155.43
    ccr-23-1122-html.html
    2
    1. scibot 07 Oct 2023
      RRID:CVCL_1547

      DOI: 10.1158/1078-0432.ccr-23-1122

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    2. scibot 07 Oct 2023
      RRID:CVCL_1547

      DOI: 10.1158/1078-0432.ccr-23-1122

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    52.53.155.43/6e7bec526fc86dd5978cecd27d77cfeec2624a0c/ccr-23-1122-html.html
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Ascorbate Elicits Anti-Cancer Activities against Non-Small Cell Lung Cancer through Hydrogen-Peroxide-Induced-DNA-Damage
    1
    1. scibot 05 Oct 2023
      RRID:CVCL_1547

      DOI: 10.3390/antiox12091775

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    ncbi.nlm.nih.gov/pmc/articles/PMC10525775/
  27. Sep 2023
  28. 52.53.155.43 52.53.155.43
    Molecular Oncology - 2023 - Horie-html.html
    1
    1. scibot 22 Sep 2023
      RRID:CVCL_1547

      DOI: 10.1002/1878-0261.13524

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    52.53.155.43/b5e8e877c627d157950951119edc64db79086ad6/Molecular Oncology - 2023 - Horie-html.html
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
    1
    1. scibot 06 Sep 2023
      RRID:CVCL_1547

      DOI: 10.1158/2767-9764.CRC-23-0304

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    ncbi.nlm.nih.gov/pmc/articles/PMC10473160/
  30. Jul 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
    1
    1. scibot 19 Jul 2023
      RRID:CVCL_1547

      DOI: 10.1158/0008-5472.CAN-21-4309

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    ncbi.nlm.nih.gov/pmc/articles/PMC9938728/
  32. www.nature.com www.nature.com
    MLK4 promotes glucose metabolism in lung adenocarcinoma through CREB-mediated activation of phosphoenolpyruvate carboxykinase and is regulated by KLF5
    1
    1. scibot 06 Jul 2023
      RRID: CVCL_1547

      DOI: 10.1038/s41389-023-00478-y

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    nature.com/articles/s41389-023-00478-y
  33. Jun 2023
  34. 52.53.155.43 52.53.155.43
    can-22-3009-html.html
    1
    1. scibot 30 Jun 2023
      RRID:CVCL_1547

      DOI: 10.1158/0008-5472.can-22-3009

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    52.53.155.43/23465825fc5c1614cd30949f4c30491df07cc998/can-22-3009-html.html
  35. www.sciencedirect.com www.sciencedirect.com
    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
    1
    1. scibot 24 Jun 2023
      RRID:CVCL_1547

      DOI: 10.1016/j.chembiol.2023.05.012

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    sciencedirect.com/science/article/pii/S2451945623001551
  36. www.mdpi.com www.mdpi.com
    Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas
    1
    1. scibot 22 Jun 2023
      RRID:CVCL_1547

      DOI: 10.3390/cells12121627

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      Curator: @jmitrevska

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    mdpi.com/2073-4409/12/12/1627
  37. Sep 2022
  38. www.sciencedirect.com www.sciencedirect.com
    The molecular network of the proteasome machinery inhibition response is orchestrated by HSP70, revealing vulnerabilities in cancer cells
    1
    1. scibot 29 Sep 2022
      RRID:CVCL_1547

      DOI: 10.1016/j.celrep.2022.111428

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    sciencedirect.com/science/article/pii/S2211124722012694
  39. www.sciencedirect.com www.sciencedirect.com
    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
    1
    1. scibot 24 Sep 2022
      CRL-5800

      DOI: 10.1016/j.ccell.2022.08.015

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      Curator: @a5munoz

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    sciencedirect.com/science/article/pii/S1535610822003798
  40. May 2022
  41. www.sciencedirect.com www.sciencedirect.com
    ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1
    1
    1. scibot 26 May 2022
      CVCL_1547

      DOI: 10.1016/j.molcel.2022.04.034

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    sciencedirect.com/science/article/pii/S1097276522004348
  42. Apr 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
    1
    1. scibot 14 Apr 2022
      RRID:CVCL_1547

      DOI: 10.1016/j.celrep.2022.110636

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    sciencedirect.com/science/article/pii/S2211124722003886
  44. Mar 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
    1
    1. scibot 18 Mar 2022
      CVCL_1547

      DOI: 10.1016/j.isci.2022.103985

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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  46. Nov 2021
  47. www.sciencedirect.com www.sciencedirect.com
    HNRNPA2B1 as a trigger of RNA switch modulates the miRNA-mediated regulation of CDK6
    1
    1. scibot 09 Nov 2021
      CRL-5800

      DOI: 10.1016/j.isci.2021.103345

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    sciencedirect.com/science/article/pii/S2589004221013146
  48. Aug 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
    1
    1. scibot 11 Aug 2021
      ATCCCRL-5800

      DOI: 10.7554/eLife.66524

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC8337080/
  50. Jul 2021
  51. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
    1
    1. scibot 30 Jul 2021
      NCI-H23

      DOI: 10.1016/j.celrep.2019.08.090

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124719311520
  52. www.sciencedirect.com www.sciencedirect.com
    Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma
    1
    1. scibot 30 Jul 2021
      H23

      DOI: 10.1016/j.ccell.2019.07.002

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1535610819303290
  53. www.sciencedirect.com www.sciencedirect.com
    BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis
    1
    1. scibot 29 Jul 2021
      RRID: CVCL_1547

      DOI: 10.1016/j.cell.2019.06.005

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0092867419306336
  54. www.sciencedirect.com www.sciencedirect.com
    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
    1
    1. scibot 29 Jul 2021
      Human: H23

      DOI: 10.1016/j.cmet.2019.06.014

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1550413119303171
  55. www.mdpi.com www.mdpi.com
    Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor
    1
    1. scibot 29 Jul 2021
      H23

      DOI: 10.3390/biom9070280

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      Curator: @Naa003

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    mdpi.com/2218-273X/9/7/280/htm
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness
    1
    1. scibot 14 Jul 2021
      RRID:CVCL_1547

      DOI: 10.7554/eLife.64212

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    ncbi.nlm.nih.gov/pmc/articles/PMC8266391/
  57. Jun 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
    1
    1. scibot 30 Jun 2021
      RRID:CVCL_1547

      DOI: 10.1016/j.celrep.2021.109291

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

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    sciencedirect.com/science/article/pii/S2211124721006628
  59. May 2021
  60. www.sciencedirect.com www.sciencedirect.com
    3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
    1
    1. scibot 07 May 2021
      RRID:CVCL_1547

      DOI: 10.1016/j.molcel.2020.10.010

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

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    sciencedirect.com/science/article/pii/S1097276520306936
  61. Mar 2021
  62. www.sciencedirect.com www.sciencedirect.com
    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
    1
    1. scibot 03 Mar 2021
      CRL-5800

      DOI: 10.1016/j.celrep.2021.108808

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

      Curator: @Naa003

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      RRIDCUR:Missing RRID:CVCL_1547
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    sciencedirect.com/science/article/pii/S2211124721001224
  63. Sep 2020
  64. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    HSPA2 Chaperone Contributes to the Maintenance of Epithelial Phenotype of Human Bronchial Epithelial Cells but Has Non-Essential Role in Supporting Malignant Features of Non-Small Cell Lung Carcinoma, MCF7, and HeLa Cancer Cells
    1
    1. scibot 29 Sep 2020
      NCI-H23

      DOI: 10.3390/cancers12102749

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_1547

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    pubmed.ncbi.nlm.nih.gov/32987811/
  65. www.mdpi.com www.mdpi.com
    Methylation Patterns and Chromatin Accessibility in Neuroendocrine Lung Cancer
    1
    1. scibot 23 Sep 2020
      CVCL_1547

      DOI: 10.3390/cancers12082003

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      RRIDCUR:Validated RRID:CVCL_1547
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    mdpi.com/2072-6694/12/8/2003
  66. www.sciencedirect.com www.sciencedirect.com
    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
    1
    1. scibot 15 Sep 2020
      RRID:CVCL_1547

      DOI: 10.1016/j.ccell.2020.03.004

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      RRID:CVCL_1547 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610820301057
  67. www.mdpi.com www.mdpi.com
    Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells
    1
    1. scibot 14 Sep 2020
      RRID:CVCL_1547

      DOI: 10.3390/cancers12040875

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

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    mdpi.com/2072-6694/12/4/875
  68. elifesciences.org elifesciences.org
    Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma
    1
    1. scibot 10 Sep 2020
      RRID:CVCL_1547

      DOI: 10.7554/eLife.53367

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    elifesciences.org/articles/53367
  69. www.sciencedirect.com www.sciencedirect.com
    KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
    1
    1. scibot 04 Sep 2020
      Human: NCI-H23

      DOI: 10.1016/j.ccell.2020.03.005

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1535610820301069
  70. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Identification and Target-Modification of SL-BBI: A Novel Bowman–Birk Type Trypsin Inhibitor from Sylvirana latouchii
    1
    1. scibot 04 Sep 2020
      H23

      DOI: 10.3390/biom10091254

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_1547

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    pubmed.ncbi.nlm.nih.gov/32872343/
  71. Jan 2020
  72. www.sciencedirect.com www.sciencedirect.com
    Activation of Oxidative Stress Response in Cancer Generates a Druggable Dependency on Exogenous Non-essential Amino Acids
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_1547

      DOI: 10.1016/j.cmet.2019.11.012

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

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    sciencedirect.com/science/article/pii/S1550413119306199
  73. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:CVCL_1547

      DOI: 10.1016/j.chembiol.2019.03.006

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2451945619300832
  74. www.sciencedirect.com www.sciencedirect.com
    MDM2 Integrates Cellular Respiration and Apoptotic Signaling through NDUFS1 and the Mitochondrial Network
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_1547

      DOI: 10.1016/j.molcel.2019.02.012

      Resource: (NCI-DTP Cat# NCI-H23, RRID:CVCL_1547)

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    sciencedirect.com/science/article/pii/S1097276519301029
  75. Nov 2018
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
    1
    1. scibot 05 Nov 2018
      NCI-H23

      Curator: @anp055

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      (KCLB Cat# 90023, RRID:CVCL_1547)

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    ncbi.nlm.nih.gov/pmc/articles/PMC3566312/
  77. www.sciencedirect.com www.sciencedirect.com
    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
    1
    1. scibot 05 Nov 2018
      CRL-5800

      Curator: @Jmenke

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      (KCLB Cat# 90023, RRID:CVCL_1547)

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    sciencedirect.com/science/article/pii/S1535610818303696
  78. www.sciencedirect.com www.sciencedirect.com
    Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor
    1
    1. scibot 05 Nov 2018
      CRL-5800

      Curator: @Jmenke

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      (KCLB Cat# 90023, RRID:CVCL_1547)

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    sciencedirect.com/science/article/pii/S0092867418300412
  79. www.sciencedirect.com www.sciencedirect.com
    Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_1547

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      (KCLB Cat# 90023, RRID:CVCL_1547)

      SciCrunch record: RRID:CVCL_1547

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      RRID:CVCL_1547
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    sciencedirect.com/science/article/pii/S1535610818301831
  80. Nov 2017
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells
    1
    1. scibot 08 Nov 2017
      CVCL_1547

      Curator: @gabimpine

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      (KCLB Cat# 90023, RRID:CVCL_1547)

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      RRID:CVCL_1547 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5345931/
  82. www.sciencedirect.com www.sciencedirect.com
    O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate
    1
    1. scibot 08 Nov 2017
      CVCL_1547

      Curator: @kaitlinsung

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      (KCLB Cat# 90023, RRID:CVCL_1547)

      SciCrunch record: RRID:CVCL_1547

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      RRID:CVCL_1547 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817300624