Hypothesis

12 Matching Annotations

Feb 2026
chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com

Structure-Based Discovery of Obeticholic Acid Derivatives as Novel Farnesoid X Receptor Partial Agonists with Improved Selectivity and Reduced Off-Target Effects

1
1. scibot 06 Feb 2026
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1002/cmdc.202500960
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202500960
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Overcoming multidrug resistance in gastrointestinal cancers with a CDH17-targeted ADC conjugated to a DNA topoisomerase inhibitor

1
1. scibot 02 Jul 2025
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1016/j.xcrm.2025.102213
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125002861
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

1
1. scibot 01 Mar 2025
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.7554/eLife.95952
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11832170/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases

1
1. scibot 26 Apr 2024
  
  in Public
  
  CVCL_1581
  
  DOI: 10.1016/j.xcrm.2024.101523
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379124001927
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

1
1. scibot 23 Jan 2024
  
  in Public
  
  CCL-251
  
  DOI: 10.1016/j.celrep.2024.113684
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724000123
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations

1
1. scibot 08 Sep 2023
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1158/2159-8290.CD-23-0475
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10481131/
Jul 2023
52.53.155.43 52.53.155.43

cd-23-0475-html.html

1
1. scibot 13 Jul 2023
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1158/2159-8290.cd-23-0475
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @olekpark
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

52.53.155.43/ab02200bf4457c1e8196af2525f73574a3d0dd99/cd-23-0475-html.html
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Novel B7-H6–Targeted IgG-Like T Cell–Engaging Antibody for the Treatment of Gastrointestinal Tumors

1
1. scibot 12 Jan 2023
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1158/1078-0432.CCR-22-2108
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9713360/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer

1
1. scibot 23 Nov 2021
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1016/j.bioorg.2021.105505
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581
Visit annotations in context

Tags

RRID:CVCL_1581

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S004520682100883X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Hyocholic acid species improve glucose homeostasis through a distinct TGR5 and FXR signaling mechanism

1
1. scibot 30 Apr 2021
  
  in Public
  
  CCL-251
  
  DOI: 10.1016/j.cmet.2020.11.017
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:CVCL_1581

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413120306525
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ursodeoxycholic acid accelerates bile acid enterohepatic circulation

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1111/bph.14705
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_1581
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_1581

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6637225/
www.sciencedirect.com www.sciencedirect.com

A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility

1
1. scibot 14 Sep 2020
  
  in Public
  
  RRID:CVCL_1581
  
  DOI: 10.1016/j.ebiom.2020.102766
  
  Resource: (ATCC Cat# CCL-251, RRID:CVCL_1581)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1581
  
  What is this?
  
  RRID:CVCL_1581 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:CVCL_1581

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2352396420301419