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A novel small-molecule inhibitor of IRF4 selectively suppresses multiple myeloma

1
1. scibot 09 Apr 2026
  
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  RRID:CVCL_1600
  
  DOI: 10.1016/j.gendis.2026.102176
  
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sciencedirect.com/science/article/pii/S2352304226001480
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

CD70-Targeting CAR NK Cells Overcome BCMA Downregulation and Improve Survival in High-risk Multiple Myeloma Models

1
1. scibot 26 Mar 2026
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/2643-3230.BCD-25-0130
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13012245/
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

BCR::ABL1-Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B-ALL Cells to Enhancer-Targeting Drugs

1
1. scibot 05 Mar 2026
  
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  CVCL_1600
  
  DOI: 10.1002/advs.202517231
  
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  Curator: @dhovakimyan1
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202517231
Feb 2026
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Targeting BCMA in multiple myeloma with a trifunctional NK cell engager

1
1. scibot 19 Feb 2026
  
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  CVCL_1600
  
  DOI: 10.1016/j.xcrm.2026.102628
  
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sciencedirect.com/science/article/pii/S2666379126000455
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APRIL-driven BCMA/TACI dual-targeted ligand–drug conjugates for selective and potent therapy of multiple myeloma

1
1. scibot 10 Feb 2026
  
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  RRID: CVCL_1600
  
  DOI: 10.1016/j.apsb.2026.02.001
  
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sciencedirect.com/science/article/pii/S2211383526001012
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Precision radiolabeled B-cell maturation nanobody for targeted PET imaging and radioligand therapy of disseminated multiple myeloma

1
1. scibot 16 Jan 2026
  
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  RRID:CVCL_1600
  
  DOI: 10.7150/thno.126920
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12775650/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma

1
1. scibot 20 Nov 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1002/advs.202510888
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12622403/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Therapeutic potential of PRMT1 as a critical survival dependency target in multiple myeloma

1
1. scibot 07 Nov 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1186/s12885-025-15104-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12584455/
Aug 2025
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Cinobufagin overcomes bortezomib resistance in multiple myeloma strains by targeting SEC62/TRPM4-mediated NECSO

1
1. scibot 19 Aug 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1016/j.phymed.2025.157171
  
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sciencedirect.com/science/article/pii/S0944711325008104
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin

1
1. scibot 04 Jul 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/0008-5472.CAN-24-0749
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
Jun 2025
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Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma

1
1. scibot 18 Jun 2025
  
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  ATCCCRL-3580
  
  DOI: 10.1016/j.molcel.2025.05.030
  
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sciencedirect.com/science/article/pii/S1097276525004691
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Pre-clinical characterization of novel multi-client inhibitors of Sec61 with broad anti-tumor activity

1
1. scibot 18 Jun 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1016/j.jpet.2025.103634
  
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sciencedirect.com/science/article/pii/S0022356525398472
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Anti-inflammatory and immunomodulatory effects in vitro of polysaccharide- and polyphenol-rich extracts of white button and Turkey Tail mushrooms

1
1. scibot 14 Jun 2025
  
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  CRL-3580™, ATCC
  
  DOI: 10.1016/j.jff.2025.106923
  
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  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1756464625002658
52.53.155.43 52.53.155.43

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2
1. scibot 14 Jun 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/1535-7163.mct-24-0846
  
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2. scibot 11 Jun 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/1535-7163.mct-24-0846
  
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52.53.155.43/36bef4761a687f6ee5c6cf9f652510edad253d31/PDF-html.html
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Interferon regulatory factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells

1
1. scibot 21 May 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1371/journal.pbio.3003096
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12052183/
Apr 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 03 Apr 2025
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/0008-5472.can-24-0749/3563696/can-24-0749.
  
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  Curator: @sjvitug
  
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52.53.155.43/73f4a278983fd3a9b93fed6443158024ffc69ddc/PDF-html.html
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Enitociclib, a selective CDK9 inhibitor: in vitro and in vivo preclinical studies in multiple myeloma

1
1. scibot 03 Apr 2025
  
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  CVCL_1600
  
  DOI: 10.1016/j.bneo.2024.100050
  
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sciencedirect.com/science/article/pii/S2950328024000505
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity

1
1. scibot 29 Mar 2025
  
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  RRID: CVCL_1600
  
  DOI: 10.1016/j.cellsig.2025.111767
  
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sciencedirect.com/science/article/pii/S0898656825001809
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy

1
1. scibot 26 Mar 2025
  
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  CRL-3580
  
  DOI: 10.1038/s43018-025-00927-0
  
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  Curator: @sjvitug
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12037409/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Maplirpacept: a CD47 decoy receptor with minimal red blood cell binding and robust anti-tumor efficacy

1
1. scibot 18 Mar 2025
  
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  RRID: CVCL_1600
  
  DOI: 10.3389/fimmu.2025.1518787
  
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  Curator: @evieth
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11897230/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Single-cell analysis of neoplastic plasma cells identifies myeloma pathobiology mediators and potential targets

1
1. scibot 24 Jan 2025
  
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  ATCCCRL-3580
  
  DOI: 10.1016/j.xcrm.2024.101925
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866523/
Dec 2024
aacrjournals.org aacrjournals.org

Kinetics of Nirogacestat-Mediated Increases in B-cell Maturation Antigen on Plasma Cells Inform Therapeutic Combinations in Multiple Myeloma

2
1. scibot 19 Dec 2024
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/2767-9764.CRC-24-0075
  
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2. scibot 13 Dec 2024
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/2767-9764.CRC-24-0075
  
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aacrjournals.org/cancerrescommun/article/4/12/3114/750524/Kinetics-of-Nirogacestat-Mediated-Increases-in-B
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Multiple mechanisms contribute to acquired TRAIL resistance in multiple myeloma

1
1. scibot 19 Aug 2024
  
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  RRID:CVCL_1600
  
  DOI: 10.1186/s12935-024-03466-3
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11299348/
Jul 2024
www.sciencedirect.com www.sciencedirect.com

Targeting the mSWI/SNF complex in POU2F-POU2AF transcription factor-driven malignancies

1
1. scibot 25 Jul 2024
  
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  RRID: CVCL_1600
  
  DOI: 10.1016/j.ccell.2024.06.006
  
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  Curator: @vtello
  
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sciencedirect.com/science/article/pii/S1535610824002319
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IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma

1
1. scibot 24 Jul 2024
  
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  RRID:CVCL_1600
  
  DOI: 10.1016/j.ccell.2024.05.026
  
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sciencedirect.com/science/article/pii/S1535610824002174
May 2024
www.nature.com www.nature.com

Global signal peptide profiling reveals principles of selective Sec61 inhibition

1
1. scibot 26 May 2024
  
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  CVCL_1600
  
  DOI: 10.1038/s41589-024-01592-7
  
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nature.com/articles/s41589-024-01592-7
Mar 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Synergistic integration of histone deacetylase inhibitors apparently enhances the cytokine-induced killer cell efficiency in multiple myeloma via the NKG2D pathway

1
1. scibot 26 Mar 2024
  
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  CVCL_1600
  
  DOI: 10.1002/cti2.1500
  
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onlinelibrary.wiley.com/doi/10.1002/cti2.1500
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Novel Anti-B-cell Maturation Antigen Alpha-Amanitin Antibody-drug Conjugate HDP-101 Shows Superior Activity to Belantamab Mafodotin and Enhanced Efficacy in Deletion 17p Myeloma Models

1
1. scibot 06 Feb 2024
  
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  RRID:CVCL_1600
  
  DOI: 10.21203/rs.3.rs-3843028/v1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10802748/
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy

1
1. scibot 11 Jan 2024
  
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  CVCL_1600
  
  DOI: 10.1016/j.ebiom.2023.104961
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10825369/
Aug 2023
52.53.155.43 52.53.155.43

Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses

3
1. scibot 19 Aug 2023
  
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  RRID:CVCL_1600
  
  DOI: 10.1016/j.celrep.2023.112925
  
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2. scibot 12 Aug 2023
  
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  RRID:CVCL_1600
  
  DOI: 10.1016/j.celrep.2023.112925
  
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3. scibot 10 Aug 2023
  
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  RRID:CVCL_1600
  
  DOI: 10.1016/j.celrep.2023.112925
  
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  Curator: @olekpark
  
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52.53.155.43/4c45d6c83e1bf2a7bb63a95a964192d48e86ccfd/PIIS2211124723009361-html.html
Jun 2023
www.nature.com www.nature.com

Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

1
1. scibot 24 Jun 2023
  
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  RRID:CVCL_1600
  
  DOI: 10.1038/s41467-023-39241-7
  
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nature.com/articles/s41467-023-39241-7
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

S100A8/S100A9 promote progression of multiple myeloma via expansion of megakaryocytes

1
1. scibot 16 Mar 2023
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/2767-9764.CRC-22-0368
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10010194/
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain

1
1. scibot 12 Jan 2023
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/1535-7163.MCT-21-0552
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9377753/
Nov 2022
aacrjournals.org aacrjournals.org

Immune phenotypes and target antigens of clonally expanded bone marrow T cells in treatment-naïve multiple myeloma

1
1. scibot 03 Nov 2022
  
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  RRID:CVCL_1600
  
  DOI: 10.1158/2326-6066.CIR-22-0434
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRID:CVCL_1600
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aacrjournals.org/cancerimmunolres/article/10/11/1407/709878/Immune-Phenotypes-and-Target-Antigens-of-Clonally
Oct 2022
www.sciencedirect.com www.sciencedirect.com

MCL-1 is a master regulator of cancer dependency on fatty acid oxidation

1
1. scibot 05 Oct 2022
  
  in Public
  
  Cat #CRL-9068
  
  DOI: 10.1016/j.celrep.2022.111445
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:CVCL_1600
  
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sciencedirect.com/science/article/pii/S2211124722012864
May 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Andrographolide, isolated from Andrographis paniculata , induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production

1
1. scibot 11 May 2022
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.12688/f1000research.53595.2
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1600
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9069414/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chromothripsis in Treatment Resistance in Multiple Myeloma

1
1. scibot 27 Jul 2021
  
  in Public
  
  NCI-H929
  
  DOI: 10.5808/GI.2017.15.3.87
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @mpairish
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRID:CVCL_1600 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC5637343/
f1000research.com f1000research.com

Andrographolide, isolated from <i>Andrographis paniculata</i><i>, </i>induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production

1
1. scibot 11 Jul 2021
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.12688/f1000research.53595.1
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @scibot
  
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f1000research.com/articles/10-542
May 2021
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Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells

1
1. scibot 28 May 2021
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.1016/j.xpro.2021.100565
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1600
  
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sciencedirect.com/science/article/pii/S2666166721002720
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Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

1
1. scibot 21 May 2021
  
  in Public
  
  CRL-9068
  
  DOI: 10.1016/j.molcel.2021.04.015
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRIDCUR:Missing RRID:CVCL_1600
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sciencedirect.com/science/article/pii/S1097276521003208
www.sciencedirect.com www.sciencedirect.com

Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.1016/j.stem.2020.12.017
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1600
  
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sciencedirect.com/science/article/pii/S1934590920306019
Apr 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Oxidatively modified low‐density lipoproteins are potential mediators of proteasome inhibitor resistance in multiple myeloma

1
1. scibot 09 Apr 2021
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.1002/ijc.33497
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRIDCUR:Validated RRID:CVCL_1600
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onlinelibrary.wiley.com/doi/10.1002/ijc.33497
Mar 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

miR‐17‐3p promotes the proliferation of multiple myeloma cells by downregulating P21 expression through LMLN inhibition

1
1. scibot 02 Mar 2021
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.1002/ijc.33528
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRID:CVCL_1600 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/full/10.1002/ijc.33528
Feb 2021
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Targeted degradation of the enhancer lysine acetyltransferases CBP and p300

1
1. scibot 28 Feb 2021
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.1016/j.chembiol.2020.12.004
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRID:CVCL_1600
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sciencedirect.com/science/article/pii/S2451945620305134
Sep 2020
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Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting

1
1. scibot 04 Sep 2020
  
  in Public
  
  NCI-H929
  
  DOI: 10.1016/j.ccell.2018.08.017
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1600
  
  Curator comments: NCI-H929 cell line DSMZ Cat# ACC-163
  
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  RRID:CVCL_1600 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1535610818303775
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.1016/j.chembiol.2019.03.006
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRID:CVCL_1600 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619300832
www.sciencedirect.com www.sciencedirect.com

Tracing MYC Expression for Small Molecule Discovery

1
1. scibot 13 Jan 2020
  
  in Public
  
  CVCL_1600
  
  DOI: 10.1016/j.chembiol.2019.02.007
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @ethanbadger
  
  SciCrunch record: CVCL_1600
  
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  RRID:CVCL_1600 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S245194561930042X
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1600
  
  DOI: 10.1016/j.chembiol.2019.02.009
  
  Resource: (DSMZ Cat# ACC-163, RRID:CVCL_1600)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1600
  
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  RRID:CVCL_1600 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2451945619300443
Nov 2017
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Stable and Potent Selenomab-Drug Conjugates

1
1. scibot 08 Nov 2017
  
  in Public
  
  H929
  
  Curator: @chewbeccax
  
  Resource used:
  
  (ECACC Cat# 95050415, RRID:CVCL_1600)
  
  SciCrunch record: RRID:CVCL_1600
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_1600 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2451945617300600