65 Matching Annotations
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    Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors
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    sciencedirect.com/science/article/pii/S2666379125004239
  3. Aug 2025
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    Imaging and targeting S1PR1 in HER2+ tumors
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    sciencedirect.com/science/article/pii/S0969805125000666
  5. Jul 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Histone Deacetylase Inhibitor Entinostat Mediates HER2 Downregulation in Gastric Cancer, Providing the Basis for Its Particular Efficacy in HER2-Amplified Tumors and in Combination Therapies
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    Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates
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  8. Jun 2025
  9. 52.53.155.43 52.53.155.43
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    Preferential tumor targeting of HER2 by iPSC-derived CAR T cells engineered to overcome multiple barriers to solid tumor efficacy
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  12. May 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessment of the Effects of Single-Domain Anti-Idiotypic Distribution Enhancers on the Disposition of Trastuzumab and on the Efficacy of a PE24-Trastuzumab Immunotoxin
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    Modulation of HER2 internalization enhances single-dose antibody-drug potency in HER2+ gastric cancer
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    Targeting PTBP3-Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis
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  16. Apr 2025
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    Expression characteristics and biological functions of CGB5 gene in gastric cancer
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel Amanitin-Based Antibody–Drug Conjugates Targeting TROP2 for the Treatment of Pancreatic Cancer
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  19. Mar 2025
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    Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
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  22. Feb 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The development and evaluation of a tublysine-based antibody-drug conjugate with enhanced tumor therapeutic efficacy
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  25. Jan 2025
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    Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat
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    The inhibition of SLC8A1 promotes Ca2+-dependent cell death in Gastric Cancer
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  28. Dec 2024
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  30. Oct 2024
  31. aacrjournals.org aacrjournals.org
    Clinical and Immunologic Responses to a B-Cell Epitope Vaccine in Patients with HER2/neu-Overexpressing Advanced Gastric Cancer—Results from Phase Ib Trial IMU.ACS.001
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  32. Sep 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase II trial of HER-Vaxx, a B cell peptide-based vaccine, in HER2-overexpressing advanced gastric cancer patients under platinum-based chemotherapy (HERIZON)
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    Starvation-induced phosphorylation activates gasdermin A to initiate pyroptosis
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  35. Aug 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vorinostat Treatment of Gastric Cancer Cells Leads to ROS-Induced Cell Inhibition and a Complex Pattern of Molecular Alterations in Nrf2-Dependent Genes
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  37. Jul 2024
  38. www.mdpi.com www.mdpi.com
    Define Critical Parameters of Trastuzumab-Mediated ADCC Assays via Assay Optimization Processes, Focusing on the Impact of Cryopreserved Effector Cells on Assay Performance
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  39. May 2024
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    Spatiotemporal quantification of HER2-targeting antibody-drug conjugate bystander activity and enhancement of solid tumor penetration
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    Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers
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  43. Apr 2024
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    Targeting the receptor tyrosine kinase MerTK shows therapeutic value in gastric adenocarcinoma
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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  47. Feb 2024
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    First-in-Human Study with preclinical data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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  51. Jan 2024
  52. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Anchoring of hyaluronan glycocalyx to CD44 reduces sensitivity of HER2-positive gastric cancer cells to trastuzumab
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    Therapeutic antibody targeting natriuretic peptide receptor 1 inhibits gastric cancer growth via BCL-2-mediated intrinsic apoptosis
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  54. Dec 2023
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel HER2-targeted therapy to overcome trastuzumab resistance in HER2-amplified gastric cancer
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  56. Sep 2023
  57. www.sciencedirect.com www.sciencedirect.com
    Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1
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  58. Aug 2023
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  60. Jul 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KRAS activation in gastric cancer stem-like cells promotes tumor angiogenesis and metastasis
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  62. Apr 2023
  63. aacrjournals.org aacrjournals.org
    Payload-binding Fab fragments increase the therapeutic index of MMAE antibody-drug conjugates
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950
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    Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2-positive cancers
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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody
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  67. Feb 2023
  68. www.sciencedirect.com www.sciencedirect.com
    VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer
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  69. Dec 2022
  70. www.mdpi.com www.mdpi.com
    Alteration of Cellular Energy Metabolism through LPAR2-Axin2 Axis in Gastric Cancer
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  71. Oct 2022
  72. www.nature.com www.nature.com
    Proteomic characterization of gastric cancer response to chemotherapy and targeted therapy reveals new therapeutic strategies
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    nature.com/articles/s41467-022-33282-0
  73. Jul 2022
  74. www.medrxiv.org www.medrxiv.org
    Transcriptomic Profiling on Localized Gastric Cancer Identified CPLX1 as a Gene Promoting Malignant Phenotype of Gastric Cancer and a Predictor of Recurrence after Surgery and Subsequent Chemotherapy
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    medrxiv.org/content/10.1101/2021.03.25.21254204v1
  75. Jun 2022
  76. link.springer.com link.springer.com
    Transcriptomic profiling on localized gastric cancer identified CPLX1 as a gene promoting malignant phenotype of gastric cancer and a predictor of recurrence after surgery and subsequent chemotherapy
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    link.springer.com/article/10.1007/s00535-022-01884-6
  77. Mar 2022
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    Lysosomal-associated membrane protein family member 5 promotes the metastatic potential of gastric cancer cells
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    link.springer.com/article/10.1007/s10120-022-01284-y
  79. Jan 2022
  80. www.dovepress.com www.dovepress.com
    <p>Dynamics of Endocytosis and Degradation of Antibody-Drug Conjugate T-DM1 in HER2 Positive Cancer Cells</p>
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  81. Jul 2021
  82. mcr.aacrjournals.org mcr.aacrjournals.org
    KRAS activation in gastric adenocarcinoma stimulates epithelial-to-mesenchymal transition to cancer stem-like cells and promotes metastasis
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  83. Local file Local file
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  84. Jun 2021
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb-202 in gastric cancer
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    onlinelibrary.wiley.com/doi/10.1002/ctm2.454
  86. May 2021
  87. www.sciencedirect.com www.sciencedirect.com
    NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells
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  88. www.mdpi.com www.mdpi.com
    Genetic and Epigenetic Alterations of CDH1 Regulatory Regions in Hereditary and Sporadic Gastric Cancer
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN is a predictive biomarker of trastuzumab resistance and prognostic factor in HER2-overexpressing gastroesophageal adenocarcinoma
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  90. Apr 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy
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  92. Sep 2020
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activity
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  94. mct.aacrjournals.org mct.aacrjournals.org
    ARX788, a Site-specific anti-HER2 Antibody Drug Conjugate, Demonstrates Potent and Selective Activity in HER2 Low and T-DM1 Resistant Breast and Gastric Cancers
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  95. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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  96. Jan 2020
  97. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EphA2‐to‐YAP Pathway Drives Gastric Cancer Growth and Therapy Resistance
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32609
  98. Nov 2018
  99. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery
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    sciencedirect.com/science/article/pii/S1931312817303931
  100. www.sciencedirect.com www.sciencedirect.com
    Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade
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    sciencedirect.com/science/article/pii/S1535610818301740