Hypothesis

25 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer

1
1. scibot 14 Aug 2025
  
  in Public
  
  CVCL_1639,
  
  DOI: 10.1093/carcin/bgae056
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11584292/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

1
1. scibot 29 Jul 2025
  
  in Public
  
  ATCC.orgCRL-2547
  
  DOI: 10.1016/j.cell.2025.06.048
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425007500
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Efficacy of Targeted Monoclonal IgA Antibodies Against Pancreatic Ductal Adenocarcinoma

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.3390/cells14090632
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12071589/
Apr 2025
www.sciencedirect.com www.sciencedirect.com

CD44 Identified as a Diagnostic Biomarker for Highly Malignant CA19-9 Negative Pancreatic Cancer

2
1. scibot 10 Apr 2025
  
  in Public
  
  RRID: CVCL_1639
  
  DOI: 10.1016/j.canlet.2025.217713
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
2. scibot 10 Apr 2025
  
  in Public
  
  CVCL_1639
  
  DOI: 10.1016/j.canlet.2025.217713
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

sciencedirect.com/science/article/pii/S0304383525002794
Aug 2024
jhoonline.biomedcentral.com jhoonline.biomedcentral.com

Heterodimerization of T cell engaging bispecific antibodies to enhance specificity against pancreatic ductal adenocarcinoma

1
1. scibot 13 Aug 2024
  
  in Public
  
  RRID: CVCL_ 1639
  
  DOI: 10.1186/s13045-024-01538-5
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

jhoonline.biomedcentral.com/articles/10.1186/s13045-024-01538-5
academic.oup.com academic.oup.com

LMO3 is a suppressor of the basal-like/squamous subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism

1
1. scibot 13 Aug 2024
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1093/carcin/bgae011
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgae011/7608949
aacrjournals.org aacrjournals.org

MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance

1
1. scibot 02 Aug 2024
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1158/1541-7786.MCR-22-0554
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

aacrjournals.org/mcr/article/21/5/444/726027/MYC-Glutamine-Dependency-Is-a-Therapeutic
May 2024
www.biorxiv.org www.biorxiv.org

ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer

1
1. scibot 29 May 2024
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1101/2024.03.12.584316
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639 DOI:10.1101/2024.03.12.584316
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RRID:CVCL_1639

DOI:10.1101/2024.03.12.584316

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scibot

URL

biorxiv.org/content/10.1101/2024.03.12.584316v1
Apr 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer

1
1. scibot 18 Apr 2024
  
  in Public
  
  RRID: CVCL_1639
  
  DOI: 10.1002/ijc.34960
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @AniH
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.34960
Nov 2023
www.sciencedirect.com www.sciencedirect.com

SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1016/j.celrep.2023.113434
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723014468
www.biorxiv.org www.biorxiv.org

LMO3 is a suppressor of the basal-like/squamous PDAC subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism

1
1. scibot 10 Nov 2023
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1101/2023.11.01.564448
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @jmitrevska
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

biorxiv.org/content/10.1101/2023.11.01.564448v1
Sep 2023
www.biorxiv.org www.biorxiv.org

ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1101/2023.09.23.558894
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @jmitrevska
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

biorxiv.org/content/10.1101/2023.09.23.558894v1
Jun 2023
aacrjournals.org aacrjournals.org

Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer

1
1. scibot 03 Jun 2023
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1158/0008-5472.CAN-22-2045
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
Apr 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950

1
1. scibot 20 Apr 2023
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1158/2767-9764.CRC-22-0310
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
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  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10112292/
www.sciencedirect.com www.sciencedirect.com

USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

1
1. scibot 08 Apr 2023
  
  in Public
  
  CVCL_1639
  
  DOI: 10.1016/j.xcrm.2023.101007
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123001179
Feb 2023
aacrjournals.org aacrjournals.org

Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

1
1. scibot 10 Feb 2023
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1158/0008-5472.CAN-22-1533
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
Dec 2022
www.nature.com www.nature.com

Table 2 Tumor cell lines used to set up less-common subcutaneous mouse tumor models

1
1. scibot 02 Dec 2022
  
  in Public
  
  CVCL_1639
  
  DOI: 10.1038/s41596-022-00709-3
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

nature.com/articles/s41596-022-00709-3/tables/2
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer

1
1. scibot 16 Nov 2022
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1016/j.xcrm.2022.100815
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

sciencedirect.com/science/article/pii/S2666379122003743
Sep 2022
www.sciencedirect.com www.sciencedirect.com

De novo sphingolipid biosynthesis necessitates detoxification in cancer cells

1
1. scibot 29 Sep 2022
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1016/j.celrep.2022.111415
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722012566
Aug 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Concurrent inhibition of IGF1R and ERK increases pancreatic cancer sensitivity to autophagy inhibitors

1
1. scibot 22 Aug 2022
  
  in Public
  
  RRID:CVCL_1639
  
  DOI: 10.1158/0008-5472.CAN-21-1443
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639
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RRID:CVCL_1639

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8886214/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
1. scibot 30 Jul 2021
  
  in Public
  
  Panc 10.05
  
  DOI: 10.1016/j.celrep.2019.08.090
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639 RRIDCUR:Missing
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RRID:CVCL_1639

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719311520
www.sciencedirect.com www.sciencedirect.com

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

1
1. scibot 27 Jul 2021
  
  in Public
  
  CRL-2547
  
  DOI: 10.1016/j.ccell.2018.10.001
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_1639
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RRID:CVCL_1639

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818304677
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer

1
1. scibot 24 Apr 2021
  
  in Public
  
  CRL-2547
  
  DOI: 10.1016/j.cell.2020.10.016
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1639
  
  What is this?
  
  RRID:CVCL_1639 RRIDCUR:Missing
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RRID:CVCL_1639

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420313222
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS

1
1. scibot 03 Sep 2020
  
  in Public
  
  Panc-10.05
  
  DOI: 10.1038/s41467-019-13973-x
  
  Resource: (ATCC Cat# CRL-2547, RRID:CVCL_1639)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1639
  
  Curator comments: ATCC Cat# CRL-2547
  
  What is this?
  
  RRID:CVCL_1639 RRIDCUR:Missing
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RRID:CVCL_1639

RRIDCUR:Missing

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6952431/