Hypothesis

21 Matching Annotations

Aug 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

SP1-Mediated Glycolytic Reprogramming Promotes Tumorigenesis and Progression in Pancreatic Cancer

1
1. scibot 21 Aug 2025
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1002/advs.202510071
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202510071
www.nature.com www.nature.com

NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers

1
1. scibot 13 Aug 2025
  
  in Public
  
  CRL-3211
  
  DOI: 10.1038/s41586-025-09299-y
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

nature.com/articles/s41586-025-09299-y
www.sciencedirect.com www.sciencedirect.com

A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers

1
1. scibot 08 Aug 2025
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1016/j.ccell.2025.07.006
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825003101
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time

1
1. scibot 30 Jul 2025
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1172/jci.insight.169105
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12288891/
Jun 2025
link.springer.com link.springer.com

Efficacy of SOAT1 Inhibitors Against Pancreatic Cancer with TP53 Mutations

1
1. scibot 05 Jun 2025
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1245/s10434-025-17482-8
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

link.springer.com/article/10.1245/s10434-025-17482-8
May 2025
www.nature.com www.nature.com

HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity

1
1. scibot 29 May 2025
  
  in Public
  
  CRL-3211
  
  DOI: 10.1038/s41467-025-60129-1
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

nature.com/articles/s41467-025-60129-1
Apr 2025
www.sciencedirect.com www.sciencedirect.com

CD44 Identified as a Diagnostic Biomarker for Highly Malignant CA19-9 Negative Pancreatic Cancer

1
1. scibot 10 Apr 2025
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1016/j.canlet.2025.217713
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

sciencedirect.com/science/article/pii/S0304383525002794
www.sciencedirect.com www.sciencedirect.com

PLK1 blockade enhances the anti-tumor effect of MAPK inhibition in pancreatic ductal adenocarcinoma

1
1. scibot 08 Apr 2025
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1016/j.celrep.2025.115541
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725003122
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Targeted degradation of CDK9 potently disrupts the MYC-regulated network

1
1. scibot 28 Mar 2025
  
  in Public
  
  CRL-3211
  
  DOI: 10.1016/j.chembiol.2025.03.001
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

sciencedirect.com/science/article/pii/S2451945625000674
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function

1
1. scibot 16 Nov 2024
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1158/1535-7163.MCT-23-0904
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11532780/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Exploiting a subtype-specific mitochondrial vulnerability for successful treatment of colorectal peritoneal metastases

1
1. scibot 26 Apr 2024
  
  in Public
  
  CVCL_1644
  
  DOI: 10.1016/j.xcrm.2024.101523
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

sciencedirect.com/science/article/pii/S2666379124001927
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

ITIH5 as a multifaceted player in pancreatic cancer suppression, impairing tyrosine kinase signaling, cell adhesion and migration

1
1. scibot 05 Apr 2024
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1002/1878-0261.13609
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
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  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13609
Feb 2023
aacrjournals.org aacrjournals.org

Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling

1
1. scibot 10 Feb 2023
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1158/0008-5472.CAN-22-1533
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
  What is this?
  
  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma

1
1. scibot 13 Dec 2022
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1186/s40170-022-00298-5
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
  What is this?
  
  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9737747/
Jul 2022
www.researchsquare.com www.researchsquare.com

Home

1
1. scibot 13 Jul 2022
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.21203/rs.3.rs-658360/v1
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
  What is this?
  
  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

researchsquare.com/
Nov 2021
www.sciencedirect.com www.sciencedirect.com

A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer

1
1. scibot 23 Nov 2021
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1016/j.bioorg.2021.105505
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1644
  
  What is this?
  
  RRID:CVCL_1644
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RRID:CVCL_1644

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scibot

URL

sciencedirect.com/science/article/pii/S004520682100883X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

1
1. scibot 17 Apr 2021
  
  in Public
  
  CRL-3211
  
  DOI: 10.1016/j.ccell.2020.04.014
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1644
  
  What is this?
  
  RRID:CVCL_1644 RRIDCUR:Missing
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RRID:CVCL_1644

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820302130
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS

1
1. scibot 03 Sep 2020
  
  in Public
  
  PSN-1
  
  DOI: 10.1038/s41467-019-13973-x
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1644
  
  Curator comments: ATCC Cat# CRL-3211
  
  What is this?
  
  RRID:CVCL_1644 RRIDCUR:Missing
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RRID:CVCL_1644

RRIDCUR:Missing

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6952431/
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Proteogenomic Network Analysis of Context-Specific KRAS Signaling in Mouse-to-Human Cross-Species Translation

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1016/j.cels.2019.07.006
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1644
  
  What is this?
  
  RRID:CVCL_1644 RRIDCUR:Validated
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RRID:CVCL_1644

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2405471219302388
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1644
  
  DOI: 10.1016/j.chembiol.2019.02.009
  
  Resource: (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1644
  
  What is this?
  
  RRID:CVCL_1644 RRIDCUR:Validated
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RRID:CVCL_1644

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2451945619300443
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of RBF1 changes glutamine catabolism

1
1. scibot 05 Nov 2018
  
  in Public
  
  PSN1
  
  Curator: @anp055
  
  Resource used:
  
  (ICLC Cat# HTL97008, RRID:CVCL_1644)
  
  SciCrunch record: RRID:CVCL_1644
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_1644 RRIDCUR:Missing
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RRID:CVCL_1644

RRIDCUR:Missing

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC3566311/