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aacrjournals.org aacrjournals.org

Milademetan in advanced solid tumors with MDM2 amplification and wild-type TP53: pre-clinical and phase 2 clinical trial results

1
1. scibot 18 Jun 2026
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1158/1078-0432.CCR-25-0762
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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aacrjournals.org/clincancerres/article/31/20/4255/766076/Milademetan-in-Advanced-Solid-Tumors-with-MDM2
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness

1
1. scibot 06 May 2026
  
  in Public
  
  CVCL_1697
  
  DOI: 10.1158/0008-5472.CAN-25-4635
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13136882/
Apr 2026
aacrjournals.org aacrjournals.org

Anti-tumor activity of trastuzumab deruxtecan in pediatric solid tumors with variable HER2 expression

1
1. scibot 09 Apr 2026
  
  in Public
  
  RRID: CVCL_1697
  
  DOI: 10.1158/1535-7163.MCT-25-0437
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1697
  
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aacrjournals.org/mct/article/25/1/156/771291/Antitumor-Activity-of-Trastuzumab-Deruxtecan-in
Feb 2026
www.biorxiv.org www.biorxiv.org

In vitro modeling of nutritional and mitochondria-targeted therapies for osteosarcoma

1
1. scibot 24 Feb 2026
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.64898/2026.02.19.706776
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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biorxiv.org/content/10.64898/2026.02.19.706776v1
Jan 2026
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Tumor Extracellular Vesicles lncOSLMT Drives Lung Inflammatory Premetastatic Niche Formation in Osteosarcoma via m6A-Dependent hnRNPA2B1/COX-2 Axis

1
1. scibot 23 Jan 2026
  
  in Public
  
  RRID: CVCL_1697
  
  DOI: 10.1002/advs.202519490
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1697
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519490
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

A triple-action PROTAC for wild-type p53 cancer therapy

1
1. scibot 29 Nov 2025
  
  in Public
  
  CVCL_1697
  
  DOI: 10.1016/j.xcrm.2025.102467
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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sciencedirect.com:5037/science/article/pii/S2666379125005403
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors

1
1. scibot 09 Sep 2025
  
  in Public
  
  American Type Culture CollectionCRL-2098
  
  DOI: 10.1016/j.xcrm.2025.102350
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1697
  
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sciencedirect.com/science/article/pii/S2666379125004239
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression

1
1. scibot 14 Aug 2025
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1186/s12967-025-06920-6
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12341233/
Jul 2025
www.sciencedirect.com www.sciencedirect.com

TRIM24 directs replicative stress responses to maintain ALT telomeres via chromatin signaling

1
1. scibot 03 Jul 2025
  
  in Public
  
  ATCCCat#: CRL-2098
  
  DOI: 10.1016/j.molcel.2025.06.009
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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sciencedirect.com/science/article/pii/S109727652500509X
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule Reactivator

1
1. scibot 12 Jun 2025
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1158/2159-8290.CD-24-1421
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12130801/
Mar 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

Biological Activity of Biomarkers Associated With Metastasis in Osteosarcoma Cell Lines

1
1. scibot 14 Mar 2025
  
  in Public
  
  CVCL_1697
  
  DOI: 10.1002/cam4.70391
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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onlinelibrary.wiley.com/doi/10.1002/cam4.70391
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma

1
1. scibot 21 Feb 2025
  
  in Public
  
  ATCCCat#CRL-2098
  
  DOI: 10.1016/j.xcrm.2025.101977
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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sciencedirect.com/science/article/pii/S2666379125000503
Dec 2024
www.nature.com www.nature.com

Frequent copy number gain of MCL1 is a therapeutic target for osteosarcoma

1
1. scibot 17 Dec 2024
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1038/s41388-024-03251-6
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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nature.com/articles/s41388-024-03251-6
Aug 2024
www.cell.com www.cell.com

Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma

1
1. scibot 13 Aug 2024
  
  in Public
  
  CRL-2098
  
  DOI: 10.14309/01.ajg.0000966496.32906.2f
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @AniH
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00188-5
May 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MDM2/MDMX inhibition by Sulanemadlin synergizes with anti-Programmed Death 1 immunotherapy in wild-type p53 tumors

1
1. scibot 25 May 2024
  
  in Public
  
  CRL-2098
  
  DOI: 10.1016/j.isci.2024.109862
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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ncbi.nlm.nih.gov/pmc/articles/PMC11112618/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach

1
1. scibot 23 Feb 2024
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1158/1078-0432.CCR-23-0873
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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ncbi.nlm.nih.gov/pmc/articles/PMC10870121/
Mar 2023
www.sciencedirect.com www.sciencedirect.com

FAM193A is a positive regulator of p53 activity

1
1. scibot 10 Mar 2023
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1016/j.celrep.2023.112230
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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sciencedirect.com/science/article/pii/S2211124723002413
Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting Podoplanin for the Treatment of Osteosarcoma

1
1. scibot 12 Jan 2023
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1158/1078-0432.CCR-21-4509
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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ncbi.nlm.nih.gov/pmc/articles/PMC9359727/
Jul 2022
www.sciencedirect.com www.sciencedirect.com

Guiding ATR and PARP inhibitor combinationswith chemogenomic screens

1
1. scibot 13 Jul 2022
  
  in Public
  
  ATCCCat#CRL-2098
  
  DOI: 10.1016/j.celrep.2022.111081
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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sciencedirect.com/science/article/pii/S2211124722008798
www.sciencedirect.com www.sciencedirect.com

METTL14-mediated epitranscriptome modification of MN1 mRNA promote tumorigenicity and all-trans-retinoic acid resistance in osteosarcoma

1
1. scibot 08 Jul 2022
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1016/j.ebiom.2022.104142
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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sciencedirect.com/science/article/pii/S2352396422003231
Jun 2022
www.sciencedirect.com www.sciencedirect.com

MDM2 binds and ubiquitinates PARP1 to enhance DNA replication fork progression

1
1. scibot 03 Jun 2022
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1016/j.celrep.2022.110879
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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sciencedirect.com/science/article/pii/S2211124722006544
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide

1
1. scibot 07 Apr 2022
  
  in Public
  
  ATCCCRL-2098
  
  DOI: 10.1016/j.celrep.2022.110630
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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sciencedirect.com/science/article/pii/S2211124722003825
aacrjournals.org aacrjournals.org

Tumor targeting with bacterial Shiga toxin B-subunit in genetic porcine models for colorectal cancer and osteosarcoma

1
1. scibot 05 Apr 2022
  
  in Public
  
  CVCL_1697
  
  DOI: 10.1158/1535-7163.MCT-21-0445
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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aacrjournals.org/mct/article/21/4/686/689560/Tumor-Targeting-with-Bacterial-Shiga-Toxin-B
Nov 2021
mct.aacrjournals.org mct.aacrjournals.org

SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents

1
1. scibot 24 Nov 2021
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1158/1535-7163.MCT-21-0089
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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mct.aacrjournals.org/content/20/11/2151
Jun 2021
cancerres.aacrjournals.org cancerres.aacrjournals.org

STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer

1
1. scibot 29 Jun 2021
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1158/0008-5472.CAN-20-2874
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697
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cancerres.aacrjournals.org/content/81/11/2943
Sep 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Novel engineered TRAIL‐based chimeric protein strongly inhibits tumor growth and bypasses TRAIL resistance

1
1. scibot 06 Sep 2020
  
  in Public
  
  CVCL_1697
  
  DOI: 10.1002/ijc.32845
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/10.1002/ijc.32845
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_1697
  
  DOI: 10.1016/j.devcel.2019.07.010
  
  Resource: (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_1697
  
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  RRID:CVCL_1697 RRIDCUR:Validated
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1534580719305829
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1697
  
  Resource used:
  
  (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  SciCrunch record: RRID:CVCL_1697
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_1697
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ncbi.nlm.nih.gov/pmc/articles/PMC5760202/
europepmc.org europepmc.org

Replication Study: Systematic identification of genomic markers of drug sensitivity in cancer cells.

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_1697
  
  Curator: @evieth
  
  Resource used:
  
  (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  SciCrunch record: RRID:CVCL_1697
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_1697 RRIDCUR:Validated
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europepmc.org/articles/PMC5760202/
Nov 2017
elifesciences.org elifesciences.org

MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect

1
1. scibot 08 Nov 2017
  
  in Public
  
  CVCL_1697
  
  Curator: @chewbeccax
  
  Resource used:
  
  (ATCC Cat# CRL-2098, RRID:CVCL_1697)
  
  SciCrunch record: RRID:CVCL_1697
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:CVCL_1697 RRIDCUR:Validated
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RRIDCUR:Validated

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elifesciences.org/articles/22477