69 Matching Annotations
  1. Jan 2026
  2. www.biorxiv.org www.biorxiv.org
    Reverse molecular pharmacology identifies the non-canonical axis of IRAK as a chemoresistance factor in neuroblastoma
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    biorxiv.org/content/10.64898/2026.01.09.697473v1
  3. Dec 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    D3-GPC2-directed CAR T cells are safe and efficacious in preclinical models of neuroblastoma and small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12699724/
  5. Aug 2025
  6. 52.53.155.43 52.53.155.43
    2025.08.10.669191v1.full-html.html
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    52.53.155.43/f08dbae15affcc9e9ce4d40e9de902464b2a7113/2025.08.10.669191v1.full-html.html
  7. Apr 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12009370/
  9. www.sciencedirect.com www.sciencedirect.com
    DNA damage response deficiency enhances neuroblastoma progression and sensitivity to combination PARP and ATR inhibition
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    sciencedirect.com/science/article/pii/S2211124725003080
  10. Jan 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Serially Quantifying TERT Rearrangement Breakpoints in ctDNA Enables Minimal Residual Disease Monitoring in Patients with Neuroblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774142/
  12. Dec 2024
  13. www.biorxiv.org www.biorxiv.org
    DKC1-mediated pseudouridylation of rRNA targets hnRNP A1 to sustain IRES-dependent translation and ATF4-driven metabolic adaptation
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    biorxiv.org/content/10.1101/2024.12.12.628228v1
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11609632/
  15. Oct 2024
  16. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Prenatal Exposure to Herbicide 2,4-Dichlorophenoxyacetic Acid (2,4D) Exacerbates Zika Virus Neurotoxicity In Vitro and In Vivo
    1
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    onlinelibrary.wiley.com/doi/10.1002/tox.24424
  17. aacrjournals.org aacrjournals.org
    Design of a Cytotoxic Neuroblastoma-Targeting Agent Using an Enzyme Acting on Polysialic Acid Fused to a Toxin
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    aacrjournals.org/mct/article/20/10/1996/665734/Design-of-a-Cytotoxic-Neuroblastoma-Targeting
  18. aacrjournals.org aacrjournals.org
    YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
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    aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
  19. Sep 2024
  20. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13714
  21. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17208
  22. Jul 2024
  23. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13702
  24. Apr 2024
  25. www.sciencedirect.com www.sciencedirect.com
    The MYCN 5′ UTR as a therapeutic target in neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124724004625
  26. Mar 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma
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    sciencedirect.com/science/article/pii/S2666379124001149
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated machine learning-driven disulfidptosis profiling: CYFIP1 and EMILIN1 as therapeutic nodes in neuroblastoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10907485/
  29. Feb 2024
  30. www.biorxiv.org www.biorxiv.org
    The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma
    1
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    biorxiv.org/content/10.1101/2024.02.20.581161v1
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC10850797/
  32. Jan 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of MYCN-amplified neuroblastoma differentiation through NMYC suppression using PPAR-γ antagonist
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    ncbi.nlm.nih.gov/pmc/articles/PMC10636585/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Oncolytic Activity of Zika Viral Therapy in Human Neuroblastoma In Vivo Models Confers a Major Survival Advantage in a CD24-dependent Manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC10775766/
  35. Dec 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Subtype-selective prenylated isoflavonoids disrupt regulatory drivers of MYCN-amplified cancers
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    sciencedirect.com/science/article/pii/S2451945623004221
  37. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Ceftriaxone exerts antitumor effects in MYCN-driven retinoblastoma and neuroblastoma by targeting DDX3X for translation repression
    1
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13553
  38. Jul 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Antagonism by CDK8 Inhibition Improves Therapeutic Efficacy of MEK Inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9938728/
  40. Jun 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Identification and targeting of protein tyrosine kinase 7 (PTK7) as an immunotherapy candidate for neuroblastoma
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    sciencedirect.com/science/article/pii/S2666379123002100
  42. link.springer.com link.springer.com
    Tumor cell-intrinsic and tumor microenvironmental conditions co-determine signaling by the glycoimmune checkpoint receptor Siglec-7
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    link.springer.com/article/10.1007/s00018-023-04816-6
  43. Apr 2023
  44. www.nature.com www.nature.com
    Spatial and temporal dynamics of ATP synthase from mitochondria toward the cell surface
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    nature.com/articles/s42003-023-04785-3
  45. Jan 2023
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phenolic glycolipid-1 of Mycobacterium leprae is involved in human Schwann cell line ST8814 neurotoxic phenotype
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15722
  47. 52.53.155.43 52.53.155.43
    Next-generation characterization of the Cancer Cell Line Encyclopedia
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    52.53.155.43/75d4069e7fa0557cf6eb2f7408b0e80fa8b043e5/SSRN-id4226197-html.html
  48. Dec 2022
  49. aacrjournals.org aacrjournals.org
    Serial profiling of circulating tumor DNA identifies dynamic evolution of clinically actionable genomic alterations in high-risk neuroblastoma
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    aacrjournals.org/cancerdiscovery/article/12/12/2800/711177/Serial-Profiling-of-Circulating-Tumor-DNA
  50. Oct 2022
  51. www.nature.com www.nature.com
    A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
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    nature.com/articles/s41467-022-33430-6
  52. Sep 2022
  53. www.nature.com www.nature.com
    The marine natural product mimic MPM-1 is cytolytic and induces DAMP release from human cancer cell lines
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    nature.com/articles/s41598-022-19597-4
  54. Jul 2022
  55. www.sciencedirect.com www.sciencedirect.com
    High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition
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    sciencedirect.com/science/article/pii/S221112472200897X
  56. aacrjournals.org aacrjournals.org
    Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment
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    aacrjournals.org/cancerrescommun/article/2/7/577/706846/Impaired-Antitumor-Immune-Response-in-MYCN
  57. link.springer.com link.springer.com
    Mutations of 1p genes do not consistently abrogate tumor suppressor functions in 1p-intact neuroblastoma
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    link.springer.com/article/10.1186/s12885-022-09800-0
  58. Jun 2022
  59. www.nature.com www.nature.com
    MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma
    1
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    nature.com/articles/s41467-022-31331-2
  60. www.sciencedirect.com www.sciencedirect.com
    Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124722007896
  61. May 2022
  62. link.springer.com link.springer.com
    The V2 receptor antagonist tolvaptan counteracts proliferation and invasivity in human cancer cells
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    link.springer.com/article/10.1007/s40618-022-01807-5
  63. Apr 2022
  64. aacrjournals.org aacrjournals.org
    MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner
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    aacrjournals.org/cancerrescommun/article/2/3/182/694085/MYCMI-7-A-Small-MYC-Binding-Compound-that-Inhibits
  65. www.sciencedirect.com www.sciencedirect.com
    ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
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    sciencedirect.com/science/article/pii/S2211124722003461
  66. Dec 2021
  67. www.sciencedirect.com www.sciencedirect.com
    GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity
    1
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    sciencedirect.com/science/article/pii/S1535610821006589
  68. mct.aacrjournals.org mct.aacrjournals.org
    Antibody-drug conjugate efficacy in neuroblastoma - role of payload, resistance mechanisms, target density, and antibody internalization
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    mct.aacrjournals.org/content/20/11/2228
  69. Aug 2021
  70. www.sciencedirect.com www.sciencedirect.com
    Soluble trivalent engagers redirect cytolytic T cell activity toward tumor endothelial marker 1
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    sciencedirect.com/science/article/pii/S2666379121002111
  71. Jul 2021
  72. www.sciencedirect.com www.sciencedirect.com
    The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy
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    sciencedirect.com/science/article/pii/S0925443919303746
  73. www.sciencedirect.com www.sciencedirect.com
    UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
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    sciencedirect.com/science/article/pii/S0092867418315162
  74. www.sciencedirect.com www.sciencedirect.com
    A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope
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    sciencedirect.com/science/article/pii/S2666379121001932
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC8253182/
  76. May 2021
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33423
  78. Feb 2021
  79. www.sciencedirect.com www.sciencedirect.com
    Isotope tracing reveals glycolysis and oxidative metabolism in childhood tumors of multiple histologies
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    sciencedirect.com/science/article/pii/S2666634021000325
  80. Jan 2021
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b
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    ncbi.nlm.nih.gov/pmc/articles/PMC7785887/
  82. Sep 2020
  83. www.sciencedirect.com www.sciencedirect.com
    11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124720311608
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model
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    ncbi.nlm.nih.gov/pmc/articles/PMC7470826/
  85. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression
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    cancerres.aacrjournals.org/content/80/17/3706
  86. www.sciencedirect.com www.sciencedirect.com
    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
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    sciencedirect.com/science/article/pii/S0092867420303445
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7255021/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased Efficacy of Histone Methyltransferase G9a Inhibitors Against MYCN-Amplified Neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC7269128/
  89. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Establishment of an in vitro 3D model for neuroblastoma enables preclinical investigation of combined tumor‐stroma drug targeting
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202000684R
  90. www.sciencedirect.com www.sciencedirect.com
    Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
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    sciencedirect.com/science/article/pii/S1097276520300083
  91. www.sciencedirect.com www.sciencedirect.com
    Large 1p36 Deletions Affecting Arid1a Locus Facilitate Mycn-Driven Oncogenesis in Neuroblastoma
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    sciencedirect.com/science/article/pii/S221112471931705X
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN‐amplified neuroblastoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32936
  93. Jan 2020
  94. www.sciencedirect.com www.sciencedirect.com
    The transcriptional repressor SNAI2 impairs neuroblastoma differentiation and inhibits response to retinoic acid therapy
    1
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    sciencedirect.com/science/article/pii/S0925443919303746
  95. Nov 2018
  96. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/38/39/8407
  97. www.sciencedirect.com www.sciencedirect.com
    Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain
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    sciencedirect.com/science/article/pii/S0969212618301771
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6021299/
  99. www.sciencedirect.com www.sciencedirect.com
    Cross-talk between Lysine-Modifying Enzymes Controls Site-Specific DNA Amplifications
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    sciencedirect.com/science/article/pii/S0092867418307864
  100. www.sciencedirect.com www.sciencedirect.com
    GPR68 Senses Flow and Is Essential for Vascular Physiology
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    sciencedirect.com/science/article/pii/S0092867418304483
  101. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2352396418301634
  102. www.ebiomedicine.com www.ebiomedicine.com
    Untitled document
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    ebiomedicine.com/article/S2352-3964(18)30163-4/abstract
  103. Nov 2017
  104. www.sciencedirect.com www.sciencedirect.com
    Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma
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    sciencedirect.com/science/article/pii/S153561081730346X