Hypothesis

24 Matching Annotations

Last 7 days
aacrjournals.org aacrjournals.org

EZH2 Inhibitors Sensitize Breast Cancer to HER2 Kinase Inhibitors through Cooperative Effects on YAP and Pro-apoptotic Regulators

1
1. scibot 11 Jul 2026
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1158/0008-5472.CAN-24-3113
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2062
  
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  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

aacrjournals.org/cancerres/article/86/6/1467/775076/EZH2-Inhibitors-Sensitize-Breast-Cancer-to-HER2
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer

1
1. scibot 17 Dec 2025
  
  in Public
  
  ATCC (American Type Culture Collection)CRL-2316
  
  DOI: 10.1016/j.xcrm.2025.102478
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

sciencedirect.com:5037/science/article/pii/S2666379125005518
Nov 2025
www.biorxiv.org www.biorxiv.org

Rewiring protein function through genetically encoded oxidative chemistry

1
1. scibot 11 Nov 2025
  
  in Public
  
  CLR-2316
  
  DOI: 10.1101/2025.11.06.686050
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

biorxiv.org/content/10.1101/2025.11.06.686050v1
Oct 2025
www.biorxiv.org www.biorxiv.org

Metabolic Alterations driven by PFKFB3 upregulation confer Resistance to Trastuzumab in HER2-Positive Breast Cancer

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1101/2025.10.09.681343
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

biorxiv.org/content/10.1101/2025.10.09.681343v1
Jul 2025
www.biorxiv.org www.biorxiv.org

Active Merlin Binds RalB to Regulate Exocytosis

1
1. scibot 12 Jul 2025
  
  in Public
  
  CRL-2316
  
  DOI: 10.1101/2025.06.13.659557
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

biorxiv.org/content/10.1101/2025.06.13.659557v1
aacrjournals.org aacrjournals.org

Development of a Novel DNA Mono-alkylator Platform for Antibody Drug Conjugates

1
1. scibot 04 Jul 2025
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1158/1535-7163.MCT-23-0622
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

aacrjournals.org/mct/article/23/4/541/741864/Development-of-a-Novel-DNA-Mono-alkylator-Platform
Nov 2024
www.biorxiv.org www.biorxiv.org

Aberrant expression of CD14 in breast tumor cells is associated with poor outcome

1
1. scibot 14 Nov 2024
  
  in Public
  
  CVCL_2062
  
  DOI: 10.1101/2024.11.07.622456
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

biorxiv.org/content/10.1101/2024.11.07.622456v1
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR

1
1. scibot 06 Feb 2024
  
  in Public
  
  ATCCCRL-2316
  
  DOI: 10.1016/j.devcel.2024.01.010
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724000303
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

1
1. scibot 23 Jan 2024
  
  in Public
  
  CRL-2316
  
  DOI: 10.1016/j.celrep.2024.113684
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724000123
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Macrophage NFATC2 mediates angiogenic signaling during mycobacterial infection

1
1. scibot 18 Dec 2022
  
  in Public
  
  ATCCCat# CRL-2316
  
  DOI: 10.1016/j.celrep.2022.111817
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @MufeiL
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722017090
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness

1
1. scibot 05 Jan 2022
  
  in Public
  
  CRL-2316
  
  DOI: 10.1016/j.cmet.2021.12.001
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_2062
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RRIDCUR:Missing

RRID:CVCL_2062

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121006203
Aug 2021
www.sciencedirect.com www.sciencedirect.com

CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1016/j.celrep.2019.11.008
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719314792
www.sciencedirect.com www.sciencedirect.com

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells

1
1. scibot 01 Aug 2021
  
  in Public
  
  CVCL_2062
  
  DOI: 10.1016/j.cels.2019.11.001
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471219303874
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1016/j.cmet.2019.01.020
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119300208
www.sciencedirect.com www.sciencedirect.com

Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation

1
1. scibot 23 Jul 2021
  
  in Public
  
  CRL2316
  
  DOI: 10.1016/j.immuni.2021.06.014
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_2062
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RRIDCUR:Missing

RRID:CVCL_2062

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scibot

URL

sciencedirect.com/science/article/pii/S1074761321002582
May 2021
www.sciencedirect.com www.sciencedirect.com

Deciphering the signaling network of breast cancer improves drug sensitivity prediction

1
1. scibot 01 May 2021
  
  in Public
  
  CRL-2316
  
  DOI: 10.1016/j.cels.2021.04.002
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471221001113
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis

1
1. scibot 11 Apr 2021
  
  in Public
  
  CVCL_2062
  
  DOI: 10.1016/j.molcel.2021.01.033
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062
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RRID:CVCL_2062

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8384339/
Nov 2020
www.sciencedirect.com www.sciencedirect.com

G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program

1
1. scibot 12 Nov 2020
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1016/j.celrep.2020.108341
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720313309
Oct 2020
www.cell.com www.cell.com

Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing

1
1. scibot 18 Oct 2020
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1016/j.chembiol.2020.07.011
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_2062
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

1
1. scibot 23 Sep 2020
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1016/j.cell.2020.05.053
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867420306863
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1016/j.celrep.2019.08.105
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124719311672
www.sciencedirect.com www.sciencedirect.com

Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2062
  
  DOI: 10.1016/j.cmet.2019.01.020
  
  Resource: (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2062
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119300208
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer

1
1. scibot 05 Nov 2018
  
  in Public
  
  CRL2316
  
  Curator: @Jmenke
  
  Resource used:
  
  (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  SciCrunch record: RRID:CVCL_2062
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867418303088
www.sciencedirect.com www.sciencedirect.com

Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_2062
  
  Curator: @evieth
  
  Resource used:
  
  (ATCC Cat# CRL-2316, RRID:CVCL_2062)
  
  SciCrunch record: RRID:CVCL_2062
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_2062 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2062

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471218300541