98 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
    1
    1. scibot 17 Jul 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.xcrm.2024.101645

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    sciencedirect.com/science/article/pii/S2666379124003598
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vitro CAR-T cell killing: validation of the potency assay
    1
    1. scibot 06 Jul 2024
      RRID:CVCL_2119

      DOI: 10.1007/s00262-024-03753-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11219661/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell–Mediated Killing of AML Leukemic Stem Cells
    1
    1. scibot 05 Jul 2024
      RRID:CVCL_2119

      DOI: 10.1158/2326-6066.CIR-23-0692

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    ncbi.nlm.nih.gov/pmc/articles/PMC11217734/
  6. Jun 2024
  7. link.springer.com link.springer.com
    β-Carboline derivatives are potent against Acute Myeloid Leukemia in vitro and in vivo
    1
    1. scibot 28 Jun 2024
      RRID:CVCL_2119

      DOI: 10.1007/s43440-024-00614-4

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    link.springer.com/article/10.1007/s43440-024-00614-4
  8. May 2024
  9. 52.53.155.43 52.53.155.43
    mct-23-0528-html.html
    1
    1. scibot 23 May 2024
      RRID:CVCL_2119

      DOI: 10.1158/1535-7163.mct-23-0528

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      RRID:CVCL_2119 DOI:10.1158/1535-7163.mct-23-0528
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    52.53.155.43/aad67d20ed53c6e2e8d83cb86f88142e832868b0/mct-23-0528-html.html
  10. www.sciencedirect.com www.sciencedirect.com
    CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
    1
    1. scibot 16 May 2024
      ACC 554

      DOI: 10.1016/j.xcrm.2024.101572

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    sciencedirect.com/science/article/pii/S2666379124002647
  11. elifesciences.org elifesciences.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 03 May 2024
      RRID:CVCL_2119

      DOI: 10.7554/eLife.90683

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    elifesciences.org/articles/90683
  12. 52.53.155.43 52.53.155.43
    cir-23-0692-html.html
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    1. scibot 03 May 2024
      RRID:CVCL_2119

      DOI: 10.1158/2326-6066.cir-23-0692

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    52.53.155.43/4a7171a4a42eb02eff7cec811e71c92b01afed3a/cir-23-0692-html.html
  13. Apr 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers
    1
    1. scibot 26 Apr 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2024.04.004

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    sciencedirect.com/science/article/pii/S1535610824001284
  15. Mar 2024
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 27 Mar 2024
      RRID:CVCL_2119

      DOI: 10.1002/1878-0261.13638

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13638
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
    1
    1. scibot 19 Mar 2024
      RRID: CVCL_2119

      DOI: 10.1158/0008-5472.CAN-23-1534

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    ncbi.nlm.nih.gov/pmc/articles/PMC10940854/
  18. Feb 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity
    1
    1. scibot 13 Feb 2024
      DSMZCat#ACC 554

      DOI: 10.1016/j.xcrm.2024.101422

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    sciencedirect.com/science/article/pii/S2666379124000454
  20. www.biorxiv.org www.biorxiv.org
    BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor
    1
    1. scibot 04 Feb 2024
      RRID:CVCL_2119

      DOI: 10.1101/2023.09.28.560054

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    biorxiv.org/content/10.1101/2023.09.28.560054v1
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Osimertinib covalently binds to CD34 and eliminates myeloid leukemia stem/progenitor cells
    1
    1. scibot 03 Feb 2024
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.CAN-23-1632

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    ncbi.nlm.nih.gov/pmc/articles/PMC10831336/
  22. Jan 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK2 Is a Key Pro-Autophagy Protein That Contributes to the High Chemoresistance and Disease Relapse in FLT3-Mutated Acute Myeloid Leukemia
    1
    1. scibot 12 Jan 2024
      CVCL_2119

      DOI: 10.3390/ijms25010646

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    ncbi.nlm.nih.gov/pmc/articles/PMC10780038/
  24. www.sciencedirect.com www.sciencedirect.com
    Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death
    1
    1. scibot 11 Jan 2024
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2023.12.015

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    sciencedirect.com/science/article/pii/S0092867423013478
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developing a mechanistic translational PK/PD model for a trifunctional NK cell engager to predict the first‐in‐human dose for acute myeloid leukemia
    1
    1. scibot 11 Jan 2024
      CVCL_2119

      DOI: 10.1111/cts.13689

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    ncbi.nlm.nih.gov/pmc/articles/PMC10772472/
  26. Dec 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
    1
    1. scibot 17 Dec 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2023.113560

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    sciencedirect.com/science/article/pii/S2211124723015723
  28. www.biorxiv.org www.biorxiv.org
    MYC–NFATC2 axis maintains cell cycle and mitochondrial function in AML cells
    1
    1. scibot 01 Dec 2023
      CVCL_2119

      DOI: 10.1101/2023.11.15.567209

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      Curator: @jmitrevska

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    biorxiv.org/content/10.1101/2023.11.15.567209v1
  29. Sep 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment
    1
    1. scibot 16 Sep 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2023.113098

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    sciencedirect.com/science/article/pii/S2211124723011099
  31. www.sciencedirect.com www.sciencedirect.com
    PARP-1 improves leukemia outcomes by inducing parthanatos during chemotherapy
    1
    1. scibot 08 Sep 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.xcrm.2023.101191

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    sciencedirect.com/science/article/pii/S2666379123003580
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MET and FGFR in Relapsed or Refractory Acute Myeloid Leukemia: Preclinical and Clinical Findings, and Signal Transduction Correlates
    1
    1. scibot 07 Sep 2023
      RRID CVCL_2119

      DOI: 10.1158/1078-0432.CCR-22-2540

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    ncbi.nlm.nih.gov/pmc/articles/PMC9992000/
  33. Aug 2023
  34. www.biorxiv.org www.biorxiv.org
    Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
    1
    1. scibot 16 Aug 2023
      RRID: CVCL_2119

      DOI: 10.1101/2023.07.26.550648

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    biorxiv.org/content/10.1101/2023.07.26.550648v2
  35. Jul 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical Evidence of an Allogeneic Dual CD20xCD22 CAR to Target a Broad Spectrum of Patients with B-cell Malignancies
    1
    1. scibot 08 Jul 2023
      RRID:CVCL_2119

      DOI: 10.1158/2326-6066.CIR-22-0910

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    ncbi.nlm.nih.gov/pmc/articles/PMC10320475/
  37. Jun 2023
  38. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
    1
    1. scibot 24 Jun 2023
      RRID:CVCL_2119

      DOI: 10.1038/s41467-023-39241-7

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    nature.com/articles/s41467-023-39241-7
  39. May 2023
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
    1
    1. scibot 10 May 2023
      RRID:CVCL_2119

      DOI: 10.1002/advs.202206098

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    onlinelibrary.wiley.com/doi/10.1002/advs.202206098
  41. Apr 2023
  42. www.nature.com www.nature.com
    Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1
    1
    1. scibot 18 Apr 2023
      RRID:CVCL_2119

      DOI: 10.1038/s41408-023-00826-6

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    nature.com/articles/s41408-023-00826-6
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
    1
    1. scibot 12 Apr 2023
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.CAN-22-2129

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    ncbi.nlm.nih.gov/pmc/articles/PMC10071820/
  44. Mar 2023
  45. www.sciencedirect.com www.sciencedirect.com
    m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
    1
    1. scibot 23 Mar 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2023.02.024

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    sciencedirect.com/science/article/pii/S109727652300151X
  46. www.sciencedirect.com www.sciencedirect.com
    Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells
    1
    1. scibot 11 Mar 2023
      CVCL_2119

      DOI: 10.1016/j.xcrm.2023.100962

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    sciencedirect.com/science/article/pii/S266637912300054X
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
    1
    1. scibot 10 Mar 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2023.02.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
  48. www.sciencedirect.com www.sciencedirect.com
    A bispecific T cell engager recruits both type 1 NKT and Vγ9Vδ2-T cells for the treatment of CD1d-expressing hematological malignancies
    1
    1. scibot 03 Mar 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.xcrm.2023.100961

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    sciencedirect.com/science/article/pii/S2666379123000538
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preclinical evaluation of CD70-specific CAR T cells targeting acute myeloid leukemia
    2
    1. scibot 02 Mar 2023
      RRID: CVCL_2119

      DOI: 10.3389/fimmu.2023.1093750

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    2. scibot 02 Mar 2023
      RRID:CVCL_2119

      DOI: 10.3389/fimmu.2023.1093750

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    ncbi.nlm.nih.gov/pmc/articles/PMC9950117/
  50. Feb 2023
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptionally imprinted glycomic signatures of acute myeloid leukemia
    1
    1. scibot 17 Feb 2023
      RRID:CVCL_2119

      DOI: 10.1186/s13578-023-00981-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC9926860/
  52. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD
    1
    1. scibot 17 Feb 2023
      RRID: CVCL_2119

      DOI: 10.1002/1878-0261.13368

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      Curator: @a5munoz

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13368
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
    1
    1. scibot 09 Feb 2023
      CVCL_2119

      DOI: 10.1158/2643-3230.BCD-21-0160

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    ncbi.nlm.nih.gov/pmc/articles/PMC9780084/
  54. Jan 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
    1
    1. scibot 28 Jan 2023
      RRID: CVCL_2119

      DOI: 10.1016/j.stem.2022.12.003

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      Curator: @sofiakhan13

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    sciencedirect.com/science/article/pii/S1934590922004878
  56. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Artesunate, a new antimalarial clinical drug, exhibits potent anti-AML activity by targeting the ROS/Bim and TFRC/Fe2+ pathways
    1
    1. scibot 14 Jan 2023
      RRID:CVCL_2119

      DOI: 10.1111/bph.15986

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  57. www.sciencedirect.com www.sciencedirect.com
    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
    1
    1. scibot 06 Jan 2023
      RRID:CVCL_2119

      DOI: 10.1016/j.stem.2022.12.006

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    sciencedirect.com/science/article/pii/S1934590922004908
  58. Dec 2022
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-tumor effect of antibody drug conjugate ASP1235 targeting Fms-like tyrosine kinase 3 with venetoclax plus azacitidine in an acute myeloid leukemia xenograft mouse model
    1
    1. scibot 31 Dec 2022
      RRID:CVCL_2119

      DOI: 10.18632/oncotarget.28331

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    ncbi.nlm.nih.gov/pmc/articles/PMC9765856/
  60. Nov 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation
    1
    1. scibot 18 Nov 2022
      RRID:CVCL_2119

      DOI: 10.7554/eLife.79940

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    ncbi.nlm.nih.gov/pmc/articles/PMC9645811/
  62. Oct 2022
  63. www.sciencedirect.com www.sciencedirect.com
    The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia
    1
    1. scibot 28 Oct 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2022.10.004

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    sciencedirect.com/science/article/pii/S1535610822004950
  64. Sep 2022
  65. www.sciencedirect.com www.sciencedirect.com
    Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
    1
    1. scibot 30 Sep 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2022.09.007

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance
    1
    1. scibot 10 Sep 2022
      CVCL_2119

      DOI: 10.1155/2022/2813938

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    ncbi.nlm.nih.gov/pmc/articles/PMC9448541/
  67. www.hindawi.com www.hindawi.com
    Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance
    1
    1. scibot 07 Sep 2022
      CVCL_2119

      DOI: 10.1155/2022/2813938

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  68. Jun 2022
  69. 52.53.155.43 52.53.155.43
    can-21-2072-html.html
    1
    1. scibot 30 Jun 2022
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.can-21-2072

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    52.53.155.43/170847d59a031feb550122423bcef303df6c67ab/can-21-2072-html.html
  70. aacrjournals.org aacrjournals.org
    Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
    1
    1. scibot 18 Jun 2022
      RRID:CVCL_2119

      DOI: 10.1158/0008-5472.CAN-21-0548

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    aacrjournals.org/cancerres/article/82/11/2141/699099/Phosphorylation-of-SHP2-at-Tyr62-Enables-Acquired
  71. May 2022
  72. www.tandfonline.com www.tandfonline.com
    JMJD1C-regulated lipid synthesis contributes to the maintenance of MLL-rearranged acute myeloid leukemia
    1
    1. scibot 11 May 2022
      RRID:CVCL_2119

      DOI: 10.1080/10428194.2022.2068004

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    tandfonline.com/doi/abs/10.1080/10428194.2022.2068004
  73. Apr 2022
  74. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
    1
    1. scibot 21 Apr 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2022.03.030

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    sciencedirect.com/science/article/pii/S0092867422003403
  75. Mar 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDK6 Degradation Is Counteracted by p16INK4A and p18INK4C in AML
    1
    1. scibot 26 Mar 2022
      RRID:CVCL_2119

      DOI: 10.3390/cancers14061554

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    ncbi.nlm.nih.gov/pmc/articles/PMC8946512/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases
    1
    1. scibot 18 Mar 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.isci.2022.103985

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    ncbi.nlm.nih.gov/pmc/articles/PMC8919295/
  78. www.sciencedirect.com www.sciencedirect.com
    The proteogenomic subtypes of acute myeloid leukemia
    1
    1. scibot 04 Mar 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2022.02.006

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    sciencedirect.com/science/article/pii/S1535610822000587
  79. www.sciencedirect.com www.sciencedirect.com
    MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape
    1
    1. scibot 04 Mar 2022
      DSMZACC 554

      DOI: 10.1016/j.molcel.2022.02.013

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    sciencedirect.com/science/article/pii/S1097276522001186
  80. Feb 2022
  81. www.sciencedirect.com www.sciencedirect.com
    HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia
    1
    1. scibot 18 Feb 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2022.01.014

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    sciencedirect.com/science/article/pii/S1097276522000570
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Overcoming tumor heterogeneity by ex vivo arming of T cells using multiple bispecific antibodies
    2
    1. scibot 11 Feb 2022
      RRID:CVCL_2119

      DOI: 10.1136/jitc-2021-003771

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      RRID:CVCL_2119

      DOI: 10.1136/jitc-2021-003771

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    ncbi.nlm.nih.gov/pmc/articles/PMC8796264/
  83. www.sciencedirect.com www.sciencedirect.com
    Inhibition of BCL2A1 by STAT5 inactivation overcomes resistance to targeted therapies of FLT3-ITD/D835 mutant AML
    1
    1. scibot 02 Feb 2022
      RRID:CVCL_2119

      DOI: 10.1016/j.tranon.2022.101354

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    sciencedirect.com/science/article/pii/S193652332200016X
  84. Jan 2022
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
    1
    1. scibot 15 Jan 2022
      RRID:CVCL_2119

      DOI: 10.1038/s41408-021-00603-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
  86. www.sciencedirect.com www.sciencedirect.com
    SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia
    1
    1. scibot 12 Jan 2022
      ACC 554

      DOI: 10.1016/j.celrep.2021.110233

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    sciencedirect.com/science/article/pii/S2211124721017423
  87. Sep 2021
  88. www.sciencedirect.com www.sciencedirect.com
    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
    1
    1. scibot 23 Sep 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2021.08.033

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    sciencedirect.com/science/article/pii/S1097276521007139
  89. www.sciencedirect.com www.sciencedirect.com
    A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells
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    1. scibot 01 Sep 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.chembiol.2021.08.004

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    sciencedirect.com/science/article/pii/S2451945621003937
  90. Aug 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
    1
    1. scibot 12 Aug 2021
      CVCL_2119

      DOI: 10.1016/j.cmet.2019.01.011

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    sciencedirect.com/science/article/pii/S1550413119300117
  92. www.sciencedirect.com www.sciencedirect.com
    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
    1
    1. scibot 07 Aug 2021
      ACC-554

      DOI: 10.1016/j.molcel.2021.07.018

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    sciencedirect.com/science/article/pii/S1097276521005876
  93. link.springer.com link.springer.com
    The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia
    1
    1. scibot 04 Aug 2021
      RRID:CVCL_2119

      DOI: 10.1007/s00277-021-04602-z

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    link.springer.com/article/10.1007/s00277-021-04602-z
  94. Jul 2021
  95. www.sciencedirect.com www.sciencedirect.com
    A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo
    1
    1. scibot 31 Jul 2021
      Human: MOLM-13

      DOI: 10.1016/j.ccell.2019.10.002

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    sciencedirect.com/science/article/pii/S1535610819304763
  96. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 30 Jul 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.chembiol.2018.11.006

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    sciencedirect.com/science/article/pii/S2451945618304136
  97. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
    1
    1. scibot 28 Jul 2021
      RRID: CVCL_2119

      DOI: 10.1016/j.cmet.2019.01.011

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    sciencedirect.com/science/article/pii/S1550413119300117
  98. www.sciencedirect.com www.sciencedirect.com
    ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
    1
    1. scibot 27 Jul 2021
      ACC-554

      DOI: 10.1016/j.ccell.2018.02.002

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    sciencedirect.com/science/article/pii/S1535610818300230
  99. Jun 2021
  100. www.sciencedirect.com www.sciencedirect.com
    MAP4K1 functions as a tumor promotor and drug mediator for AML via modulation of DNA damage/repair system and MAPK pathway
    1
    1. scibot 23 Jun 2021
      CVCL_2119

      DOI: 10.1016/j.ebiom.2021.103441

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    sciencedirect.com/science/article/pii/S2352396421002346
  101. jitc.bmj.com jitc.bmj.com
    T cell engaging bispecific antibodies targeting CD33 IgV and IgC domains for the treatment of acute myeloid leukemia
    1
    1. scibot 12 Jun 2021
      RRID:CVCL_2119

      DOI: 10.1136/jitc-2021-002509

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    jitc.bmj.com/content/9/5/e002509
  102. May 2021
  103. www.sciencedirect.com www.sciencedirect.com
    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
    1
    1. scibot 18 May 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2021.04.022

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    sciencedirect.com/science/article/pii/S009286742100502X
  104. www.sciencedirect.com www.sciencedirect.com
    Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation
    1
    1. scibot 12 May 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2021.109101

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    sciencedirect.com/science/article/pii/S2211124721004356
  105. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Targeting DNA damage repair functions of two histone deacetylases, HDAC8 and SIRT6, sensitizes acute myeloid leukemia to NAMPT inhibition
    1
    1. scibot 10 May 2021
      RRID:CVCL_2119

      DOI: 10.1158/1078-0432.CCR-20-3724

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    clincancerres.aacrjournals.org/content/27/8/2352
  106. www.sciencedirect.com www.sciencedirect.com
    CRISPR screens in physiologic medium reveal conditionally essential genes in human cells
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      RRID:CVCL_2119

      DOI: 10.1016/j.cmet.2021.02.005

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    sciencedirect.com/science/article/pii/S1550413121000619
  107. Apr 2021
  108. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
    1
    1. scibot 22 Apr 2021
      ACC 554

      DOI: 10.1016/j.ccell.2020.10.010

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  109. www.sciencedirect.com www.sciencedirect.com
    Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis
    1
    1. scibot 19 Apr 2021
      RRID:CVCL_2119

      DOI: 10.1016/j.molcel.2021.02.012

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    sciencedirect.com/science/article/pii/S1097276521000988
  110. www.sciencedirect.com www.sciencedirect.com
    Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia
    1
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      ACC 554

      DOI: 10.1016/j.ccell.2020.05.014

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  111. www.sciencedirect.com www.sciencedirect.com
    Immunogenomic Landscape of Hematological Malignancies
    1
    1. scibot 17 Apr 2021
      CVCL_2119

      DOI: 10.1016/j.ccell.2020.06.002

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610820302750
  112. Mar 2021
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
    1
    1. scibot 02 Mar 2021
      RRID:CVCL_2119

      DOI: 10.7554/eLife.65905

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @scibot

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119
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    ncbi.nlm.nih.gov/pmc/articles/PMC7886351/
  114. Sep 2020
  115. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 25 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2019.12.002

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_2119

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      RRIDCUR:Validated RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S1535610819305720
  116. www.nature.com www.nature.com
    High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
    1
    1. scibot 23 Sep 2020
      CVCL_2119

      DOI: 10.1038/s41467-020-17209-1

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119 RRIDCUR:Validated
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    nature.com/articles/s41467-020-17209-1
  117. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
    1
    1. scibot 16 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.celrep.2020.107840

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @Naa003

      SciCrunch record: RRID:CVCL_2119

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      RRIDCUR:Validated RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S2211124720308214
  118. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells
    1
    1. scibot 06 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.stem.2020.03.016

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590920301387
  119. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.
    1
    1. scibot 04 Sep 2020
      CVCL_2119

      DOI: 10.1158/1078-0432.CCR-19-1900

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119
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    clincancerres.aacrjournals.org/content/26/13/3371
  120. www.sciencedirect.com www.sciencedirect.com
    Allosteric Activators of Protein Phosphatase 2A Display Broad Antitumor Activity Mediated by Dephosphorylation of MYBL2
    1
    1. scibot 04 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.cell.2020.03.051

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S0092867420303445
  121. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
    1
    1. scibot 04 Sep 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.stem.2020.04.001

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S1934590920301405
  122. www.sciencedirect.com www.sciencedirect.com
    RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia
    1
    1. scibot 04 Sep 2020
      RRID: CVCL_2119

      DOI: 10.1016/j.stem.2020.04.009

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S193459092030148X
  123. www.sciencedirect.com www.sciencedirect.com
    Highly Parallel Quantification and Compartment Localization of Transcription Factors and Nuclear Proteins
    1
    1. scibot 03 Sep 2020
      MOLM13

      DOI: 10.1016/j.celrep.2020.01.096

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720301303
  124. Aug 2020
  125. www.nature.com www.nature.com
    High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
    1
    1. scibot 23 Aug 2020
      RRID:CVCL_2119

      DOI: 10.1038/s41467-020-17209-1

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119
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    nature.com/articles/s41467-020-17209-1
  126. Jan 2020
  127. www.sciencedirect.com www.sciencedirect.com
    HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_2119

      DOI: 10.1016/j.ccell.2019.10.011

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @ethanbadger

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819304854
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
    1
    1. scibot 13 Jan 2020
      RRID:CVCL_2119

      DOI: 10.1038/s41408-018-0165-5

      Resource: (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      Curator: @evieth

      SciCrunch record: RRID:CVCL_2119

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      RRID:CVCL_2119 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
  129. Nov 2018
  130. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_2119

      Curator: @Jmenke

      Resource used:

      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      SciCrunch record: RRID:CVCL_2119

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_2119 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610818300126
  131. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethality of Combined Bcl-2 Inhibition and p53 Activation in AML: Mechanisms and Superior Antileukemic Efficacy
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_2119

      Resource used:

      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      SciCrunch record: RRID:CVCL_2119

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S1535610817305020
  132. www.sciencedirect.com www.sciencedirect.com
    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
    1
    1. scibot 05 Nov 2018
      RRID:CVCL_2119

      Resource used:

      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      SciCrunch record: RRID:CVCL_2119

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_2119
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    sciencedirect.com/science/article/pii/S1535610817305159
  133. Nov 2017
  134. www.sciencedirect.com www.sciencedirect.com
    Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      ACC 554

      Curator: @Jmenke

      Resource used:

      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      SciCrunch record: RRID:CVCL_2119

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_2119 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610817303641
  135. www.sciencedirect.com www.sciencedirect.com
    Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia
    1
    1. scibot 08 Nov 2017
      MOLM13

      Curator: @kaitlinsung

      Resource used:

      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      SciCrunch record: RRID:CVCL_2119

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_2119 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416316853
  136. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia
    1
    1. scibot 08 Nov 2017
      ACC 554

      Curator: @gabimpine

      Resource used:

      (DSMZ Cat# ACC-554, RRID:CVCL_2119)

      SciCrunch record: RRID:CVCL_2119

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:CVCL_2119 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416311540