79 Matching Annotations
  1. Last 7 days
  2. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Dual-Barrier Remodeling of Solid Tumors by a Selenium-Photothermal Peptide Assembly for NK Cell-Oriented Immunotherapy
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.71631
  3. Jul 2026
  4. aacrjournals.org aacrjournals.org
    FOSL1 Orchestrates Epigenetic Reprogramming of Anaplastic Thyroid Cancer and Suppresses Natural Killer Cell-Mediated Antitumor Immunity
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    aacrjournals.org/cancerres/article/86/9/2184/784010/FOSL1-Orchestrates-Epigenetic-Reprogramming-of
  5. May 2026
  6. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR-NK Therapeutic Strategies
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202521188
  7. www.sciencedirect.com www.sciencedirect.com
    NK cell dysfunction and interferon gamma production underlie autoinflammation in mevalonate kinase deficiency
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    sciencedirect.com/science/article/pii/S107476132600138X
  8. Apr 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiation-induced MYB reduction unleashes TIM-3 expression in NK cells to attenuate antitumor immunity in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13088527/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The p53 tumor suppressor modulates the expression of proteins that control natural killer cell activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC13072665/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Orosomucoid 2 promotes colorectal cancer liver metastasis by suppressing natural killer cell-mediated antitumor immunity by remodeling the serine and one-carbon metabolism pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC13067650/
  12. 54.241.53.176 54.241.53.176
    A Fully Human Pan VL9 HLAE TCRm Antibody Enables Functional Dissection of HLAE Biology and Checkpoint Signaling
    2
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    54.241.53.176/089c0d54aafa939862e15036a250ae2fa17f1db6/1-s2.0-S2589004226010448-main-html.html
  13. Mar 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining lenalidomide with IL-2 family of cytokines enhances activating receptor and perforin/granzyme expression in NK cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12981494/
  15. Feb 2026
  16. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    High-Throughput 3D Matrigel-based Droplet Microfluidics for Single-Cell Function-to-Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions
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    advanced.onlinelibrary.wiley.com/doi/10.1002/admt.202501801
  17. Jan 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809113/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune gene diversity and STING1 variants in shaping cancer immunity across different genetic ancestry populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13019158/
  20. Dec 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anti-FAP CAR-NK cells as a novel targeted therapy against cervical cancer and cancer-associated fibroblasts
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    pmc.ncbi.nlm.nih.gov/articles/PMC12716053/
  22. Nov 2025
  23. link.springer.com link.springer.com
    An immunometabolic prodrug strategy overcomes DHODH inhibitor resistance in refractory melanoma
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    link.springer.com/article/10.1186/s13046-025-03566-6
  24. Oct 2025
  25. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511573
  26. Sep 2025
  27. www.biorxiv.org www.biorxiv.org
    USP18 Inhibition Enhances Type I Interferon Signalling and Immune Activation in the Tumour Microenvironment of Triple-Negative Breast Cancer
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    biorxiv.org/content/10.1101/2025.09.01.672152v1
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The FcγRIIIA (CD16) L48-H/R polymorphism enhances NK cell-mediated antibody-dependent cellular cytotoxicity by promoting serial killing
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    pmc.ncbi.nlm.nih.gov/articles/PMC11879761/
  29. www.sciencedirect.com www.sciencedirect.com
    DDX3X mutation and Epstein-Barr virus cooperate to induce R-loop-dependent oncogenesis
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    sciencedirect.com/science/article/pii/S2211124725010083
  30. Aug 2025
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A PSMA-targeted Tri-specific Killer Engager enhances NK cell cytotoxicity against prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790377/
  32. Jul 2025
  33. www.cell.com www.cell.com
    1-s2.0-S1525001625005799-main-html.html
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    cell.com/molecular-therapy-family/molecular-therapy/abstract/S1525-0016(25)00579-9
  34. www.sciencedirect.com www.sciencedirect.com
    Effectorless Fc-fusion improves FLT3L drug-like properties for cancer immunotherapy combinations
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    sciencedirect.com/science/article/pii/S235239642500266X
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12214879/
  36. Jun 2025
  37. link.springer.com link.springer.com
    The puzzling regulation of the interferon signaling system by the p53 tumor suppressor protein
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    link.springer.com/article/10.1007/s00018-025-05763-0
  38. www.sciencedirect.com www.sciencedirect.com
    Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling
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    sciencedirect.com/science/article/pii/S153561082500220X
  39. May 2025
  40. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225007849-main-html.html
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    52.53.155.43/9bda4f9104814416ec1118877f6674b001237189/1-s2.0-S2589004225007849-main-html.html
  41. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225008090-main-html.html
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    52.53.155.43/9127131bdf1d38e6512c3fe44ba4bd8593683c0c/1-s2.0-S2589004225008090-main-html.html
  42. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of β2 integrin activation by talin unveils subunit-specific mechanisms of integrin signaling
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    sciencedirect.com/science/article/pii/S221112472500378X
  43. Apr 2025
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optogenetically engineered Septin-7 enhances immune cell infiltration of tumor spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11536090/
  45. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/73f4a278983fd3a9b93fed6443158024ffc69ddc/PDF-html.html
  46. Mar 2025
  47. www.sciencedirect.com www.sciencedirect.com
    A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S0092867425002910
  48. Feb 2025
  49. www.biorxiv.org www.biorxiv.org
    Spike-specific IgG4 generated post BNT162b2 mRNA vaccination is inhibitory when directly competing with functional IgG subclasses
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    biorxiv.org/content/10.1101/2025.02.12.637095v1
  50. aacrjournals.org aacrjournals.org
    The E3 ubiquitin ligase FBXO38 maintains the antitumor function of natural killer cells by sustaining IL-15R signaling
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    aacrjournals.org/cancerimmunolres/article/12/10/1438/748724/The-E3-Ubiquitin-Ligase-FBXO38-Maintains-the
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process
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    pmc.ncbi.nlm.nih.gov/articles/PMC11820107/
  52. www.biorxiv.org www.biorxiv.org
    A Human Neuron Alzheimer’s Disease Model Reveals Barriers to Senolytic Translatability
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    biorxiv.org/content/10.1101/2025.01.28.635165v1
  53. Jan 2025
  54. www.sciencedirect.com www.sciencedirect.com
    Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
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    sciencedirect.com/science/article/pii/S2666634024003775
  55. Dec 2024
  56. www.sciencedirect.com www.sciencedirect.com
    RNA sensing induced by chromosome missegregation augments anti-tumor immunity
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    sciencedirect.com/science/article/pii/S109727652400950X
  57. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    sciencedirect.com/science/article/pii/S235239642400495X
  58. Nov 2024
  59. www.sciencedirect.com www.sciencedirect.com
    Co-Colorectal cancer stem cells employ the FADS1/DDA axis to evade NK cell-mediated immunosuppression after co-cultured with NK cells under hypoxia
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    sciencedirect.com/science/article/pii/S1567576924020575
  60. Sep 2024
  61. www.cell.com www.cell.com
    SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
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    cell.com/cell-reports/fulltext/S2211-1247(24)00865-9
  62. Jul 2024
  63. www.mdpi.com www.mdpi.com
    Microbiota-Derived Short-Chain Fatty Acids Boost Antitumoral Natural Killer Cell Activity
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    mdpi.com/2077-0383/13/13/3885
  64. May 2024
  65. www.sciencedirect.com www.sciencedirect.com
    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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    sciencedirect.com/science/article/pii/S1535610824001697
  66. www.sciencedirect.com www.sciencedirect.com
    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
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    sciencedirect.com/science/article/pii/S1074761324002590
  67. Apr 2024
  68. www.sciencedirect.com www.sciencedirect.com
    A comprehensive single-cell breast tumor atlas defines epithelial and immune heterogeneity and interactions predicting anti-PD-1 therapy response
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    sciencedirect.com/science/article/pii/S2666379124001800
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000115/
  70. Feb 2024
  71. aacrjournals.org aacrjournals.org
    Exosomal lncRNA NEAT1 inhibits NK cell activity to promote multiple myeloma cell immune escape via an EZH2/PBX1 axis
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    aacrjournals.org/mcr/article/22/2/125/733692/Exosomal-lncRNA-NEAT1-Inhibits-NK-Cell-Activity-to
  72. Jan 2024
  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Non-IL-2-blocking anti-CD25 antibody inhibits tumor growth by depleting Tregs and has synergistic effects with anti-CTLA-4 therapy
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34823
  74. Dec 2023
  75. www.sciencedirect.com www.sciencedirect.com
    Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis
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    sciencedirect.com/science/article/pii/S0092867423012321
  76. www.biorxiv.org www.biorxiv.org
    Androgen receptor signaling blockade enhances NK cell-mediated killing of prostate cancer cells and sensitivity to NK cell checkpoint blockade
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    biorxiv.org/content/10.1101/2023.11.15.567201v1
  77. 52.53.155.43 52.53.155.43
    mcr-23-0282-html.html
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    52.53.155.43/84a2cafa1a1e5c07eb694e27ebb2771a1c12d751/mcr-23-0282-html.html
  78. Aug 2023
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eradication of CD48 positive tumors by selectively enhanced YTS cells harnessing the lncRNA NeST
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    ncbi.nlm.nih.gov/pmc/articles/PMC10440710/
  80. www.sciencedirect.com www.sciencedirect.com
    LncRNA TYMSOS facilitates breast cancer metastasis and immune escape through downregulating ULBP3
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    sciencedirect.com/science/article/pii/S2589004223016334
  81. Jul 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10342141/
  83. Apr 2023
  84. aacrjournals.org aacrjournals.org
    IOA-244 is a Non–ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance
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    aacrjournals.org/cancerrescommun/article/3/4/576/725855/IOA-244-is-a-Non-ATP-competitive-Highly-Selective
  85. Mar 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A tri-specific killer engager against mesothelin targets NK cells towards lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9992642/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9934544/
  88. Nov 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC9648415/
  90. Sep 2022
  91. www.sciencedirect.com www.sciencedirect.com
    MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer
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    sciencedirect.com/science/article/pii/S1535610822003798
  92. aacrjournals.org aacrjournals.org
    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
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    aacrjournals.org/cancerrescommun/article/2/8/842/708157/Na-H-exchanger-1-Enhances-Antitumor-Activity-of
  93. Jun 2022
  94. www.sciencedirect.com www.sciencedirect.com
    Measuring trogocytosis between ovarian tumor and natural killer cells
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    sciencedirect.com/science/article/pii/S2666166722003057
  95. May 2022
  96. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial damage-associated molecular patterns trigger arginase-dependent lymphocyte immunoregulation
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    sciencedirect.com/science/article/pii/S2211124722006209
  97. Mar 2022
  98. link.springer.com link.springer.com
    IL-10 contributes to gemcitabine resistance in extranodal NK/T-cell lymphoma cells via ABCC4
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    link.springer.com/article/10.1007/s10637-022-01224-8
  99. Oct 2021
  100. www.sciencedirect.com www.sciencedirect.com
    Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications
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    sciencedirect.com/science/article/pii/S2666166721005803
  101. Sep 2021
  102. www.sciencedirect.com www.sciencedirect.com
    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
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    sciencedirect.com/science/article/pii/S2211124721010755
  103. Aug 2021
  104. www.sciencedirect.com www.sciencedirect.com
    Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA
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    sciencedirect.com/science/article/pii/S2211124721009712
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7858242/
  106. Jul 2021
  107. www.sciencedirect.com www.sciencedirect.com
    Morphological profiling of human T and NK lymphocytes by high-content cell imaging
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    sciencedirect.com/science/article/pii/S221112472100694X
  108. Jun 2021
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8193615/
  110. Apr 2021
  111. www.sciencedirect.com www.sciencedirect.com
    Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria
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    sciencedirect.com/science/article/pii/S0092867420314537
  112. Sep 2020
  113. www.sciencedirect.com www.sciencedirect.com
    Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells
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    sciencedirect.com/science/article/pii/S2666379120300033
  114. www.sciencedirect.com www.sciencedirect.com
    Genomic and Transcriptomic Characterization of Natural Killer T Cell Lymphoma
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    sciencedirect.com/science/article/pii/S1535610820300945
  115. www.sciencedirect.com www.sciencedirect.com
    Modulation of Extracellular ISG15 Signaling by Pathogens and Viral Effector Proteins
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    sciencedirect.com/science/article/pii/S221112472030752X
  116. Jan 2020
  117. www.nature.com www.nature.com
    The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy
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    nature.com/articles/s41419-019-1950-1
  118. www.sciencedirect.com www.sciencedirect.com
    Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin
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    sciencedirect.com/science/article/pii/S2451945619301175
  119. Nov 2018
  120. www.cell.com www.cell.com
    Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity
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    cell.com/cell-stem-cell/fulltext/S1934-5909(18)30284-4