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Aug 2025
www.sciencedirect.com www.sciencedirect.com

The extracellular-matrix-remodeling capability exposes therapeutic vulnerability in a subset of renal cell carcinomas with tumor thrombi

1
1. scibot 07 Aug 2025
  
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  RRID:CVCL_2174
  
  DOI: 10.1016/j.devcel.2025.07.010
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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sciencedirect.com/science/article/pii/S1534580725004484
Jul 2025
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Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy

1
1. scibot 29 Jul 2025
  
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  ATCCCRL-2947
  
  DOI: 10.1016/j.cell.2025.07.004
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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sciencedirect.com/science/article/pii/S0092867425007937
aacrjournals.org aacrjournals.org

PF-08046032: A Novel, Investigational CD25-Directed Antibody–Drug Conjugate Optimized for Selective Depletion of Regulatory T Cells in Advanced Malignant Tumors

1
1. scibot 12 Jul 2025
  
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  RRID:CVCL_2174
  
  DOI: 10.1158/1535-7163.MCT-25-0101
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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aacrjournals.org/mct/article/24/7/963/763162/PF-08046032-A-Novel-Investigational-CD25-Directed
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225010132-main-html.html

1
1. scibot 29 May 2025
  
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  RRID:CVCL_2174
  
  DOI: 10.1016/j.isci.2025.112752
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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52.53.155.43/9003c45fae7689dd9660ec2260acff69b9d30974/1-s2.0-S2589004225010132-main-html.html
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 20 May 2025
  
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  RRID:CVCL_2174
  
  DOI: 10.1158/1535-7163.mct-25-0101
  
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52.53.155.43/8722bce88cb39afedfdfb86cbdceb511fd6e5381/PDF-html.html
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape

1
1. scibot 01 Mar 2025
  
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  RRID:CVCL_2174
  
  DOI: 10.7554/eLife.95952
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11832170/
Feb 2025
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Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

1
1. scibot 11 Feb 2025
  
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  CVCL_2174
  
  DOI: 10.1016/j.ccell.2025.01.004
  
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sciencedirect.com/science/article/pii/S1535610825000224
Jan 2025
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Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1

1
1. scibot 14 Jan 2025
  
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  RRID:CVCL_2174
  
  DOI: 10.1016/j.cmet.2024.11.012
  
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sciencedirect.com/science/article/pii/S1550413124004807
52.53.155.43 52.53.155.43

PDF-html.html

2
1. scibot 04 Jan 2025
  
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  CRL-2947
  
  DOI: 10.1093/jleuko/qiae257
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
  Curator: @sjvitug
  
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2. scibot 03 Jan 2025
  
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  CRL-2947
  
  DOI: 10.1093/jleuko/qiae257
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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52.53.155.43/a7add4eb960dfe089f5e9dc2796b5e4220c88ac6/qiae257-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting macrophage circadian rhythms with microcurrent stimulation to activate cancer immunity through phagocytic defense

1
1. scibot 04 Jan 2025
  
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  RRID:CVCL_2174
  
  DOI: 10.7150/thno.100748
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11671381/
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint

1
1. scibot 24 Nov 2024
  
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  RRID:CVCL_2174
  
  DOI: 10.1016/j.immuni.2024.10.013
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
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sciencedirect.com/science/article/pii/S107476132400493X
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ANGPTL4 suppresses clear cell renal cell carcinoma via inhibition of lysosomal acid lipase

1
1. scibot 29 Aug 2024
  
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  Renca
  
  DOI: 10.1158/2767-9764.CRC-24-0016
  
  Resource: (BCRJ Cat# 0346, RRID:CVCL_2174)
  
  Curator: @vtello
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11348483/
Jul 2024
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CXCL3/TGF-β-Mediated Crosstalk Between CAFs and Tumor Cells Augments RCC Progression and Sunitinib Resistance

1
1. scibot 19 Jul 2024
  
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  RRID:CVCL_2174
  
  DOI: 10.1016/j.isci.2024.110224
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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sciencedirect.com/science/article/pii/S2589004224014494
Jun 2024
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De novo and salvage purine synthesis pathways across tissues and tumors

1
1. scibot 04 Jun 2024
  
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  CRL-2947
  
  DOI: 10.1016/j.cell.2024.05.011
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @abever99
  
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  DOI:10.1016/j.cell.2024.05.011 RRID:CVCL_2174
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sciencedirect.com/science/article/pii/S0092867424005208
May 2024
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Development of a PAK4-targeting PROTAC for renal carcinoma therapy: concurrent inhibition of cancer cell proliferation and enhancement of immune cell response

1
1. scibot 30 May 2024
  
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  RRID:CVCL_2174
  
  DOI: 10.1016/j.ebiom.2024.105162
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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sciencedirect.com/science/article/pii/S235239642400197X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma

1
1. scibot 17 May 2024
  
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  RRID:CVCL_2174
  
  DOI: 10.1158/0008-5472.CAN-23-2521
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11094425/
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Next-generation anti-PD-L1/IL-15 immunocytokine elicits superior antitumor immunity in cold tumors with minimal toxicity

1
1. scibot 02 May 2024
  
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  CRL-2947
  
  DOI: 10.1016/j.xcrm.2024.101531
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S2666379124002003
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

SETD2 loss and ATR inhibition synergize to promote cGAS signaling and immunotherapy response in renal cell carcinoma

1
1. scibot 03 Apr 2024
  
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  RRID:CVCL_2174
  
  DOI: 10.1158/1078-0432.CCR-23-1003
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10592192/
Mar 2024
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

Combining VPS34 inhibitors with STING agonists enhances type I interferon signaling and anti-tumor efficacy

1
1. scibot 28 Mar 2024
  
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  RRID:CVCL_2174
  
  DOI: 10.1002/1878-0261.13619
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13619
Feb 2024
www.sciencedirect.com www.sciencedirect.com

SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion

1
1. scibot 02 Feb 2024
  
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  RRID: CVCL_2174
  
  DOI: 10.1016/j.cell.2024.01.008
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S0092867424000102
Jan 2024
transmedcomms.biomedcentral.com transmedcomms.biomedcentral.com

iMN041 is an immunotherapeutic and an effective treatment in mouse xenograft models of pancreatic cancer, renal cancer and triple negative breast cancer

1
1. scibot 25 Jan 2024
  
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  RRID:CVCL_2174
  
  DOI: 10.1186/s41231-024-00161-3
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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transmedcomms.biomedcentral.com/articles/10.1186/s41231-024-00161-3
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Necrotic Cells from Head and Neck Carcinomas Release Biomolecules That Are Activating Toll-like Receptor 3

1
1. scibot 19 Jan 2024
  
  in Public
  
  CVCL_2174
  
  DOI: 10.3390/ijms242015269
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10607619/
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

1
1. scibot 09 Jan 2024
  
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  CRL-2947
  
  DOI: 10.1016/j.ccell.2023.12.005
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S1535610823004336
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells

1
1. scibot 18 Nov 2023
  
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  RRID:CVCL_2174
  
  DOI: 10.3390/cells12212558
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10649679/
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy

1
1. scibot 13 Oct 2023
  
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  RRID:CVCL_2174
  
  DOI: 10.1016/j.molcel.2023.09.007
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1097276523007025
Aug 2023
www.biorxiv.org www.biorxiv.org

TIM3 is a context-dependent co-regulator of cytotoxic T cell function

1
1. scibot 12 Aug 2023
  
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  RRID:CVCL_2174
  
  DOI: 10.1101/2023.08.03.551797
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
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biorxiv.org/content/10.1101/2023.08.03.551797v1
dx.doi.org dx.doi.org

NL-201 upregulates MHC-I expression and intratumoral TCR diversity, and demonstrates robust antitumor activity as monotherapy and in combination with PD-1 blockade

1
1. scibot 09 Aug 2023
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1158/2326-6066.CIR-22-0304
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
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dx.doi.org/10.1158/2326-6066.CIR-22-0304
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Five inhibitory receptors display distinct vesicular distributions in T cells

1
1. scibot 03 Aug 2023
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1101/2023.07.21.550019
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10370166/
Apr 2023
52.53.155.43 52.53.155.43

A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma

1
1. scibot 07 Apr 2023
  
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  RRID:CVCL_2174
  
  DOI: 10.1002/1878-0261.13401
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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52.53.155.43/50807bad4ac98194c420b81c9bc8a62408d03259/Molecular Oncology - 2023 - Montemagno - A group of novel VEGF splice variants as alternative therapeutic targets in renal-html.html
Mar 2023
www.sciencedirect.com www.sciencedirect.com

TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy

1
1. scibot 22 Mar 2023
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1016/j.jbc.2023.104621
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0021925823002636
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

BACH1 promotes clear cell renal cell carcinoma progression by upregulating oxidative stress‐related tumorigenicity

1
1. scibot 15 Feb 2023
  
  in Public
  
  CVCL_2174
  
  DOI: 10.1111/cas.15607
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9899607/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer

1
1. scibot 21 Jan 2023
  
  in Public
  
  CVCL_2174
  
  DOI: 10.1016/j.celrep.2023.112016
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S221112472300027X
onlinelibrary.wiley.com onlinelibrary.wiley.com

Immunotherapies targeting neoantigens are effective in PD-1 blockade-resistant tumors

1
1. scibot 10 Jan 2023
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1002/ijc.34382
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34382
Jan 2022
www.nature.com www.nature.com

Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization

1
1. scibot 15 Jan 2022
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1038/s42003-021-02972-8
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRID:CVCL_2174
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RRID:CVCL_2174

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scibot

URL

nature.com/articles/s42003-021-02972-8
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis

1
1. scibot 17 Aug 2021
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1158/0008-5472.CAN-20-1876
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRID:CVCL_2174
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RRID:CVCL_2174

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8026491/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity

1
1. scibot 23 Jul 2021
  
  in Public
  
  CRL-2947
  
  DOI: 10.1016/j.ccell.2021.06.018
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRID:CVCL_2174 RRIDCUR:Missing
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RRID:CVCL_2174

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610821003408
May 2021
www.sciencedirect.com www.sciencedirect.com

Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1016/j.jconrel.2021.03.015
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2174
  
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  RRID:CVCL_2174
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RRID:CVCL_2174

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scibot

URL

sciencedirect.com/science/article/pii/S0168365921001267
Apr 2021
www.cell.com www.cell.com

Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

1
1. scibot 24 Apr 2021
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1016/j.cell.2020.11.009
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRID:CVCL_2174
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RRID:CVCL_2174

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scibot

URL

cell.com/cell/fulltext/S0092-8674(20)31526-9
Nov 2020
www.frontiersin.org www.frontiersin.org

Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy

1
1. scibot 25 Nov 2020
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: DOI:10.3389/fimmu.2020.584423
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_2174
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RRID:CVCL_2174

RRIDCUR:Validated

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scibot

URL

frontiersin.org/articles/10.3389/fimmu.2020.584423/full
Sep 2020
www.nature.com www.nature.com

Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1038/s41596-020-0299-3
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_2174
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RRID:CVCL_2174

RRIDCUR:Validated

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scibot

URL

nature.com/articles/s41596-020-0299-3
onlinelibrary.wiley.com onlinelibrary.wiley.com

The immunogenic potential of bacterial flagella for Salmonella‐mediated tumor therapy

1
1. scibot 15 Sep 2020
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1002/ijc.32807
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_2174
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RRID:CVCL_2174

RRIDCUR:Validated

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scibot

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onlinelibrary.wiley.com/doi/10.1002/ijc.32807
www.cell.com www.cell.com

Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1016/j.cell.2020.02.019
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRID:CVCL_2174
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RRID:CVCL_2174

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scibot

URL

cell.com/cell/fulltext/S0092-8674(20)30163-X
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2174
  
  DOI: 10.1016/j.celrep.2018.12.017
  
  Resource: (CLS Cat# 400321/p768_RenCa, RRID:CVCL_2174)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2174
  
  What is this?
  
  RRID:CVCL_2174 RRIDCUR:Validated
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RRID:CVCL_2174

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124718319284