Hypothesis

21 Matching Annotations

Last 7 days
www.pnas.org www.pnas.org

AML1-ETO hijacks a distal enhancer of NAT10 to reprogram glutathione metabolism and sustain leukemia stem cell stemness

1
1. scibot 29 Oct 2026
  
  in Public
  
  RRID: CVCL_2196
  
  DOI: 10.1073/pnas.2608310123
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @zeplar
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

pnas.org/doi/10.1073/pnas.2608310123
Sep 2026
www.sciencedirect.com www.sciencedirect.com

5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia

1
1. scibot 16 Sep 2026
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.molcel.2026.08.018
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276526005873
Jul 2026
onlinelibrary.wiley.com onlinelibrary.wiley.com

<fc>DHX15</fc> affects <fc>AML1</fc>‐<fc>ETO9a</fc> splicing together with <fc>HNRNPL</fc>, <fc>RBM33</fc> in <fc>AML1</fc>‐<fc>ETO</fc>‐positive acute myeloid leukaemia

1
1. scibot 21 Jul 2026
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1111/bjh.70658
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

onlinelibrary.wiley.com/doi/10.1111/bjh.70658
aacrjournals.org aacrjournals.org

Loss of SETD8 Impairs Mitochondrial Homeostasis to Suppress Leukemia Stem Cell Function in t(8;21) Acute Myeloid Leukemia

1
1. scibot 11 Jul 2026
  
  in Public
  
  RRID: CVCL_2196
  
  DOI: 10.1158/0008-5472.CAN-24-3659
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

aacrjournals.org/cancerres/article/85/21/4122/766740/Loss-of-SETD8-Impairs-Mitochondrial-Homeostasis-to
May 2026
www.sciencedirect.com www.sciencedirect.com

Leukemic stem cell subtypes determine venetoclax resistance and therapeutic vulnerabilities in AML

1
1. scibot 08 May 2026
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.stem.2026.04.012
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @nmaralla
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590926001529
Jan 2026
www.sciencedirect.com www.sciencedirect.com

Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia

1
1. scibot 23 Jan 2026
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.celrep.2025.116875
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472501647X
Oct 2025
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Chronic ER Stress Triggers Cell-Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

1
1. scibot 28 Oct 2025
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1002/advs.202511573
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511573
www.biorxiv.org www.biorxiv.org

Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1101/2025.10.13.682235
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.10.13.682235v1
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PROTAC-Mediated GSPT1 Degradation Impairs the Expression of Fusion Genes in Acute Myeloid Leukemia

1
1. scibot 29 Jan 2025
  
  in Public
  
  RRID: CVCL_2196
  
  DOI: 10.3390/cancers17020211
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11763475/
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth

1
1. scibot 15 Feb 2024
  
  in Public
  
  CVCL_2196
  
  DOI: 10.1038/s41467-024-45691-4
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10867020/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.xcrm.2023.101290
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @olekpark
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379123004846
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15

2
1. scibot 29 Sep 2023
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.isci.2023.107844
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
2. scibot 29 Sep 2023
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.isci.2023.107844
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
May 2023
www.biorxiv.org www.biorxiv.org

Leukemic stem cells hijack lineage inappropriate signalling pathways to promote their growth

1
1. scibot 04 May 2023
  
  in Public
  
  CVCL_2196
  
  DOI: 10.1101/2023.03.10.532081
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

biorxiv.org/content/10.1101/2023.03.10.532081v2
Aug 2022
www.sciencedirect.com www.sciencedirect.com

hiPSC-derived bone marrow milieu identifies a clinically actionable driver of niche-mediated treatment resistance in leukemia

1
1. scibot 17 Aug 2022
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.xcrm.2022.100717
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379122002609
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:CVCL_2196
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6179967/
Sep 2020
clincancerres.aacrjournals.org clincancerres.aacrjournals.org

5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.

1
1. scibot 04 Sep 2020
  
  in Public
  
  CVCL_2196
  
  DOI: 10.1158/1078-0432.CCR-19-1900
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

clincancerres.aacrjournals.org/content/26/13/3371
www.cell.com www.cell.com

The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation

1
1. scibot 04 Sep 2020
  
  in Public
  
  RRID: CVCL_2196
  
  DOI: 10.1016/j.ccell.2018.08.015
  
  Resource: (DSMZ Cat# ACC-690, RRID:CVCL_2196)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2196
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

cell.com/cancer-cell/fulltext/S1535-6108(18)30375-1
Nov 2018
www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_2196
  
  Resource used:
  
  (JCRB Cat# JCRB1170, RRID:CVCL_2196)
  
  SciCrunch record: RRID:CVCL_2196
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6179967/
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:CVCL_2196
  
  Curator: @evieth
  
  Resource used:
  
  (JCRB Cat# JCRB1170, RRID:CVCL_2196)
  
  SciCrunch record: RRID:CVCL_2196
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_2196 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:CVCL_2196

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818303751
www.sciencedirect.com www.sciencedirect.com

CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis

1
1. scibot 05 Nov 2018
  
  in Public
  
  CVCL_2196
  
  Resource used:
  
  (JCRB Cat# JCRB1170, RRID:CVCL_2196)
  
  SciCrunch record: RRID:CVCL_2196
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_2196
Visit annotations in context

Tags

RRID:CVCL_2196

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818302216