28 Matching Annotations
  1. Aug 2025
  2. www.biorxiv.org www.biorxiv.org
    Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer
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    biorxiv.org/content/10.1101/2025.08.10.669554v1
  3. Jul 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combining EHMT and PARP Inhibition: A Strategy to Diminish Therapy-Resistant Ovarian Cancer Tumor Growth while Stimulating Immune Activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11543919/
  5. Jan 2025
  6. www.nature.com www.nature.com
    Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage
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    nature.com/articles/s41556-024-01557-x
  7. Dec 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Regulation of human interferon signaling by transposon exonization
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    sciencedirect.com/science/article/pii/S0092867424013333
  9. Oct 2024
  10. www.biorxiv.org www.biorxiv.org
    Ablation of hematopoietic stem cell derived adipocytes reduces tumor burden in syngeneic mouse models of high-grade serous carcinoma
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    biorxiv.org/content/10.1101/2024.09.19.613924v3
  11. Aug 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor intrinsic activity of Chromobox 2 (CBX2) remodels the tumor microenvironment in high grade serous carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11298703/
  13. www.tandfonline.com www.tandfonline.com
    Novel chromobox 2 inhibitory peptide decreases tumor progression
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    tandfonline.com/doi/full/10.1080/14728222.2023.2218614
  14. Jun 2024
  15. www.cell.com www.cell.com
    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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    cell.com/iscience/abstract/S2589-0042(24)01200-8
  16. Apr 2024
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    VDX-111, a novel small molecule, induces necroptosis to inhibit ovarian cancer progression
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    onlinelibrary.wiley.com/doi/10.1002/mc.23721
  18. www.nature.com www.nature.com
    Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade
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    nature.com/articles/s41467-024-47069-y
  19. Feb 2024
  20. www.sciencedirect.com www.sciencedirect.com
    SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424000102
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma
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    sciencedirect.com/science/article/pii/S2211124723013190
  23. Oct 2023
  24. www.biorxiv.org www.biorxiv.org
    Regulation of human interferon signaling by transposon exonization
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    biorxiv.org/content/10.1101/2023.09.11.557241v1
  25. Sep 2023
  26. www.sciencedirect.com www.sciencedirect.com
    The interplay of TARG1 and PARG protects against genomic instability
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    sciencedirect.com/science/article/pii/S2211124723011245
  27. Jul 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9812934/
  29. Jun 2023
  30. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
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    nature.com/articles/s41467-023-39241-7
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10281290/
  32. www.tandfonline.com www.tandfonline.com
    Novel chromobox 2 inhibitory peptide decreases tumor progression
    1
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    tandfonline.com/doi/full/10.1080/14728222.2023.2218614
  33. Mar 2023
  34. www.biorxiv.org www.biorxiv.org
    Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models
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    biorxiv.org/content/10.1101/2023.02.23.529773v1
  35. Feb 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting DUSP activity as a treatment for high grade serous ovarian carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9357222/
  37. Jul 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8936832/
  39. Jun 2022
  40. 52.53.155.43 52.53.155.43
    mct-21-0682-html.html
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    52.53.155.43/ab9f52410f4c75a7a2713f4530b957e6dadc45f9/mct-21-0682-html.html
  41. Feb 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ratio of toxic-to-nontoxic microRNAs predicts platinum sensitivity in ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8338879/
  43. Dec 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer
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    sciencedirect.com/science/article/pii/S2666379121003438
  45. May 2021
  46. www.sciencedirect.com www.sciencedirect.com
    PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells
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    sciencedirect.com/science/article/pii/S1097276520305815
  47. Sep 2020
  48. mcr.aacrjournals.org mcr.aacrjournals.org
    EZH2 loss drives resistance to carboplatin and paclitaxel in serous ovarian cancers expressing ATM
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    mcr.aacrjournals.org/content/18/2/278
  49. Jan 2020
  50. www.mdpi.com www.mdpi.com
    The Metabolic Inhibitor CPI-613 Negates Treatment Enrichment of Ovarian Cancer Stem Cells
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    mdpi.com/2072-6694/11/11/1678/htm
  51. mcr.aacrjournals.org mcr.aacrjournals.org
    PARP Inhibition Induces Enrichment of DNA Repair–Proficient CD133 and CD117 Positive Ovarian Cancer Stem Cells
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    mcr.aacrjournals.org/content/17/2/431