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22 Matching Annotations

Jun 2026
www.sciencedirect.com www.sciencedirect.com

An orally active dual CBP/p300 degrader targets core dependencies of multiple myeloma

1
1. scibot 04 Jun 2026
  
  in Public
  
  RRID: CVCL_2989
  
  DOI: 10.1016/j.celrep.2026.117464
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @nmaralla
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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sciencedirect.com/science/article/pii/S2211124726005425
Apr 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting PRKCN, an Essential Driver Orchestrating mTOR‐IRF4 Axis Independently of Kinase Activity, in Multiple Myeloma

1
1. scibot 15 Apr 2026
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1002/advs.202518975
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC13073330/
Feb 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Anti-myeloma activity of the CXCR4 antagonist WZ811

1
1. scibot 20 Feb 2026
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1007/s00109-026-02650-4
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12913330/
www.sciencedirect.com www.sciencedirect.com

Targeting BCMA in multiple myeloma with a trifunctional NK cell engager

1
1. scibot 19 Feb 2026
  
  in Public
  
  CVCL_2989
  
  DOI: 10.1016/j.xcrm.2026.102628
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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sciencedirect.com/science/article/pii/S2666379126000455
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Cinobufagin overcomes bortezomib resistance in multiple myeloma strains by targeting SEC62/TRPM4-mediated NECSO

1
1. scibot 19 Aug 2025
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1016/j.phymed.2025.157171
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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sciencedirect.com/science/article/pii/S0944711325008104
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Interferon regulatory factor 4 mediates nonenzymatic IRE1 dependency in multiple myeloma cells

1
1. scibot 17 May 2025
  
  in Public
  
  CVCL_2989
  
  DOI: 10.1371/journal.pbio.3003096
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12052183/
Apr 2025
link.springer.com link.springer.com

A novel indirubin- 3-monoxime derivative I3MV- 8b exhibits remarkable cytotoxicity against multiple myeloma by targeting TRIM28

1
1. scibot 10 Apr 2025
  
  in Public
  
  CVCL_2989
  
  DOI: 10.1186/s40364-025-00773-3
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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link.springer.com/article/10.1186/s40364-025-00773-3
Jul 2024
www.mdpi.com www.mdpi.com

Functional Investigation of IGF1R Mutations in Multiple Myeloma

1
1. scibot 19 Jul 2024
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.3390/cancers16112139
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

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mdpi.com/2072-6694/16/11/2139
www.sciencedirect.com www.sciencedirect.com

Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death

1
1. scibot 18 Jul 2024
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1016/j.celrep.2024.114445
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724007745
May 2024
www.sciencedirect.com www.sciencedirect.com

Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma

1
1. scibot 09 May 2024
  
  in Public
  
  JCRB1179
  
  DOI: 10.1016/j.celrep.2024.114211
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724005394
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1016/j.ccell.2023.11.001
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

sciencedirect.com/science/article/pii/S1535610823003665
May 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

miR‐17‐3p promotes the proliferation of multiple myeloma cells by downregulating P21 expression through LMLN inhibition

1
1. scibot 05 May 2023
  
  in Public
  
  RRID: CVCL_2989
  
  DOI: 10.1002/ijc.33528
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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onlinelibrary.wiley.com/doi/full/10.1002/ijc.33528
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma

1
1. scibot 31 Dec 2022
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.3390/ijms232416162
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9786043/
Aug 2021
www.biorxiv.org www.biorxiv.org

Scalable, FACS-Free Genome-Wide Phenotypic Screening

1
1. scibot 13 Aug 2021
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1101/612887
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

biorxiv.org/content/10.1101/612887v1
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Tracing MYC Expression for Small Molecule Discovery

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1016/j.chembiol.2019.02.007
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

sciencedirect.com/science/article/pii/S245194561930042X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chromothripsis in Treatment Resistance in Multiple Myeloma

1
1. scibot 27 Jul 2021
  
  in Public
  
  KMS-11
  
  DOI: 10.5808/GI.2017.15.3.87
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @mpairish
  
  SciCrunch record: RRID:CVCL_2989
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_2989
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RRIDCUR:Missing

RRID:CVCL_2989

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5637343/
May 2021
www.sciencedirect.com www.sciencedirect.com

Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1016/j.stem.2020.12.017
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

sciencedirect.com/science/article/pii/S1934590920306019
Feb 2021
www.sciencedirect.com www.sciencedirect.com

Targeted degradation of the enhancer lysine acetyltransferases CBP and p300

1
1. scibot 28 Feb 2021
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1016/j.chembiol.2020.12.004
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_2989
  
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  RRID:CVCL_2989
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RRID:CVCL_2989

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scibot

URL

sciencedirect.com/science/article/pii/S2451945620305134
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.3390/ijms21176314
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_2989
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_2989
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RRIDCUR:Validated

RRID:CVCL_2989

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scibot

URL

pubmed.ncbi.nlm.nih.gov/32878237/
Jan 2020
www.nature.com www.nature.com

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.1038/s41551-019-0454-8
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2989
  
  What is this?
  
  RRID:CVCL_2989 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2989

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scibot

URL

nature.com/articles/s41551-019-0454-8
elifesciences.org elifesciences.org

Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:CVCL_2989
  
  DOI: 10.7554/eLife.47084
  
  Resource: (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_2989
  
  What is this?
  
  RRID:CVCL_2989 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2989

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scibot

URL

elifesciences.org/articles/47084
Nov 2017
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

One reporter for in-cell activity profiling of majority of protein kinase oncogenes

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:CVCL_2989
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (JCRB Cat# JCRB1179, RRID:CVCL_2989)
  
  SciCrunch record: RRID:CVCL_2989
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_2989 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:CVCL_2989

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5310841/