Hypothesis

33 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer

1
1. scibot 14 Aug 2025
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1093/carcin/bgae056
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11584292/
May 2025
www.nature.com www.nature.com

HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity

1
1. scibot 29 May 2025
  
  in Public
  
  CRL-1837
  
  DOI: 10.1038/s41467-025-60129-1
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

nature.com/articles/s41467-025-60129-1
Apr 2025
www.nature.com www.nature.com

Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways

1
1. scibot 04 Apr 2025
  
  in Public
  
  ATCC Cat# CRL-1837
  
  DOI: 10.1038/s41598-025-95766-5
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

nature.com/articles/s41598-025-95766-5
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Small-molecule inhibitor BAY synergizes with gemcitabine through AHR inhibition in pancreatic cancer cells

1
1. scibot 21 Feb 2025
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1016/j.bcp.2025.116798
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

sciencedirect.com/science/article/pii/S0006295225000607
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225001026-main-html.html

1
1. scibot 23 Jan 2025
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1016/j.isci.2025.111842
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

52.53.155.43/9cdc52fc0b70ce3d9f24b335db5892b38840adb3/1-s2.0-S2589004225001026-main-html.html
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint

1
1. scibot 24 Nov 2024
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1016/j.immuni.2024.10.013
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

sciencedirect.com/science/article/pii/S107476132400493X
www.sciencedirect.com www.sciencedirect.com

Cancer-associated fibroblasts maintain critical pancreatic cancer cell lipid homeostasis in the tumor microenvironment

1
1. scibot 14 Nov 2024
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1016/j.celrep.2024.114972
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724013238
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CALB2 drives pancreatic cancer metastasis through inflammatory reprogramming of the tumor microenvironment

1
1. scibot 05 Oct 2024
  
  in Public
  
  CVCL_3881
  
  DOI: 10.1186/s13046-024-03201-w
  
  Resource: (RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11448066/
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes

1
1. scibot 03 Jul 2024
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.3389/fonc.2024.1403052
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11190739/
May 2024
www.biorxiv.org www.biorxiv.org

ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer

1
1. scibot 29 May 2024
  
  in Public
  
  RRID:CVCL_3881)
  
  DOI: 10.1101/2024.03.12.584316
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @abever99
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881 DOI:10.1101/2024.03.12.584316
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RRID:CVCL_3881

DOI:10.1101/2024.03.12.584316

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scibot

URL

biorxiv.org/content/10.1101/2024.03.12.584316v1
Apr 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer

1
1. scibot 18 Apr 2024
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1002/ijc.34960
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

onlinelibrary.wiley.com/doi/10.1002/ijc.34960
Mar 2024
academic.oup.com academic.oup.com

LMO3 is a suppressor of the basal-like/squamous subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism

1
1. scibot 22 Mar 2024
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1093/carcin/bgae011
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgae011/7608949
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer

1
1. scibot 12 Mar 2024
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1038/s41420-024-01890-y
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10924943/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1016/j.celrep.2023.113434
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723014468
www.biorxiv.org www.biorxiv.org

LMO3 is a suppressor of the basal-like/squamous PDAC subtype and reduces disease aggressiveness of pancreatic cancer through glycerol 3-phosphate metabolism

1
1. scibot 10 Nov 2023
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1101/2023.11.01.564448
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
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  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

biorxiv.org/content/10.1101/2023.11.01.564448v1
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Impact of CRISPR/Cas9-Mediated CD73 Knockout in Pancreatic Cancer

1
1. scibot 18 Oct 2023
  
  in Public
  
  RRID: CVCL_3881
  
  DOI: 10.3390/cancers15194842
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10572021/
Sep 2023
www.biorxiv.org www.biorxiv.org

ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer

1
1. scibot 30 Sep 2023
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1101/2023.09.23.558894
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

biorxiv.org/content/10.1101/2023.09.23.558894v1
Jun 2023
www.nature.com www.nature.com

Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

1
1. scibot 24 Jun 2023
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1038/s41467-023-39241-7
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

nature.com/articles/s41467-023-39241-7
May 2023
aacrjournals.org aacrjournals.org

RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition

1
1. scibot 05 May 2023
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1158/1078-0432.CCR-21-4291
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

aacrjournals.org/clincancerres/article/28/14/3091/706867/RASGRF1-Fusions-Activate-Oncogenic-RAS-Signaling
Mar 2023
www.nature.com www.nature.com

Non-canonical functions of SNAIL drive context-specific cancer progression

1
1. scibot 09 Mar 2023
  
  in Public
  
  CVCL_3881
  
  DOI: 10.1038/s41467-023-36505-0
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

nature.com/articles/s41467-023-36505-0
Jan 2022
journals.sagepub.com journals.sagepub.com

Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021

1
1. scibot 12 Jan 2022
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1177/24725552211038362
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

journals.sagepub.com/doi/full/10.1177/24725552211038362
Dec 2021
journals.sagepub.com journals.sagepub.com

Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021

3
1. scibot 23 Dec 2021
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1177/24725552211038362
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
2. scibot 15 Dec 2021
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1177/24725552211038362
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
3. scibot 04 Dec 2021
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1177/24725552211038362
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

journals.sagepub.com/doi/full/10.1177/24725552211038362
www.nature.com www.nature.com

Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

1
1. scibot 03 Dec 2021
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1038/s42003-021-02842-3
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @evieth
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

nature.com/articles/s42003-021-02842-3
Nov 2021
journals.sagepub.com journals.sagepub.com

Complex Tumor Spheroids, a Tissue-Mimicking Tumor Model, for Drug Discovery and Precision Medicine - Gurmeet Kaur, David M. Evans, Beverly A. Teicher, Nathan P. Coussens, 2021

2
1. scibot 18 Nov 2021
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1177/24725552211038362
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
2. scibot 16 Nov 2021
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1177/24725552211038362
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

journals.sagepub.com/doi/full/10.1177/24725552211038362
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
1. scibot 30 Jul 2021
  
  in Public
  
  SU.86.86
  
  DOI: 10.1016/j.celrep.2019.08.090
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRIDCUR:Missing RRID:CVCL_3881
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RRID:CVCL_3881

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719311520
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells

1
1. scibot 01 Jul 2021
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.18632/oncotarget.27989
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8238250/
Nov 2020
link.springer.com link.springer.com

CREPT serves as a biomarker of poor survival in pancreatic ductal adenocarcinoma

2
1. scibot 03 Nov 2020
  
  in Public
  
  RRID: CLCV_4056
  
  DOI: 10.1007/s13402-020-00569-7
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_3881
  
  Curator comments: SU.86.86 cell line ATCC Cat# CRL-1837
  
  What is this?
  
  RRID:CVCL_3881
2. scibot 03 Nov 2020
  
  in Public
  
  RRID: CLCV_3881
  
  DOI: 10.1007/s13402-020-00569-7
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_3881
  
  Curator comments: SU.86.86 cell line ATCC Cat# CRL-1837
  
  What is this?
  
  RRID:CVCL_3881
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RRID:CVCL_3881

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scibot

URL

link.springer.com/article/10.1007/s13402-020-00569-7
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

1
1. scibot 16 Sep 2020
  
  in Public
  
  RRID:CVCL_3881
  
  DOI: 10.1016/j.celrep.2020.107840
  
  Resource: (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_3881
  
  What is this?
  
  RRIDCUR:Validated RRID:CVCL_3881
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RRIDCUR:Validated

RRID:CVCL_3881

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720308214
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport

1
1. scibot 08 Nov 2017
  
  in Public
  
  CRL-1837
  
  Curator: @Jmenke
  
  Resource used:
  
  (IZSLER Cat# BS TCL 180, RRID:CVCL_3881)
  
  SciCrunch record: RRID:CVCL_3881
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:CVCL_3881 RRIDCUR:Missing
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RRID:CVCL_3881

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276517305087