32 Matching Annotations
  1. Jul 2025
  2. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695179/
  4. Jun 2025
  5. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70073
  6. May 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  8. Jan 2025
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11774231/
  10. Oct 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Development of an orally bioavailable CDK12/13 degrader and induction of synthetic lethality with AKT pathway inhibition
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    sciencedirect.com/science/article/pii/S2666379124004828
  12. Sep 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610824003179
  14. Aug 2024
  15. 52.53.155.43 52.53.155.43
    FEBS Press
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    52.53.155.43/4e85ba1ed1516c780407b3a64dcb4d2814a68c56/Molecular Oncology - 2023 - Gonthier - Isocitrate dehydrogenase 1 sustains a hybrid cytoplasmic mitochondrial tricarboxylic-html.html
  16. Jul 2024
  17. www.biorxiv.org www.biorxiv.org
    Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer
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    biorxiv.org/content/10.1101/2024.07.09.602803v1
  18. Apr 2024
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ERBB3 overexpression is enriched in diverse patient populations with castration-sensitive prostate cancer and is associated with a unique AR activity signature
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    ncbi.nlm.nih.gov/pmc/articles/PMC11016893/
  20. Mar 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  22. www.sciencedirect.com www.sciencedirect.com
    Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
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    sciencedirect.com/science/article/pii/S1535610824000485
  23. Nov 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine prostate cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10658857/
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of the Cyclin K-CDK12 complex induces DNA damage and increases the effect of androgen deprivation therapy in prostate cancer
    1
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34778
  26. Oct 2023
  27. link.springer.com link.springer.com
    Impact of sequencing of androgen receptor-signaling inhibition and radiotherapy in prostate cancer: importance of homologous recombination disruption
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    link.springer.com/article/10.1007/s00345-023-04649-9
  28. Jul 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10373600/
  30. Jun 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer
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    sciencedirect.com/science/article/pii/S1535610823001836
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression and Therapeutic Targeting of TROP-2 in Treatment-Resistant Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10261916/
  33. Oct 2022
  34. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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    elifesciences.org/articles/81083
  35. Sep 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversible epigenetic alterations regulate class I HLA loss in prostate cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437063/
  37. Jul 2022
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteome profiling of enzalutamide-resistant cell lines and serum analysis identified ALCAM as marker of resistance in castration-resistant prostate cancer
    1
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34159
  39. Apr 2022
  40. www.sciencedirect.com www.sciencedirect.com
    A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway
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    sciencedirect.com/science/article/pii/S258900422200445X
  41. Jan 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8254790/
  43. www.nature.com www.nature.com
    The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer
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    nature.com/articles/s41467-021-26901-9
  44. Dec 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I
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    sciencedirect.com/science/article/pii/S2451945621004797
  46. Nov 2021
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL cooperates with EGFR to mediate neutrophil elastase-induced migration of prostate cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8567381/
  48. Jul 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/
  50. www.sciencedirect.com www.sciencedirect.com
    CREB5 Promotes Resistance to Androgen-Receptor Antagonists and Androgen Deprivation in Prostate Cancer
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    sciencedirect.com/science/article/pii/S2211124719313828
  51. May 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
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    sciencedirect.com/science/article/pii/S0092867421004955
  53. Nov 2020
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Thyroid and androgen receptor signaling are antagonized by CRYM in prostate cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33332
  55. Sep 2020
  56. www.nature.com www.nature.com
    A Systematic Study of the Impact of Estrogens and Selective Estrogen Receptor Modulators on Prostate Cancer Cell Proliferation
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    nature.com/articles/s41598-020-60844-3
  57. Jan 2020
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6414201/