58 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Genotoxic antibody-drug conjugates combined with Bcl-xL inhibitors enhance therapeutic efficacy in metastatic castration-resistant prostate cancer
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    biorxiv.org/content/10.1101/2025.09.05.674562v1
  3. Sep 2025
  4. journals.plos.org journals.plos.org
    A novel sialylation pathway mediated by extracellular vesicles in aggressive prostate cancer
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    journals.plos.org/plosone/article
  5. Aug 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeted Deletion of Cxcl1 in MSCs Regulates Osteogenesis and Suppresses Bone-Metastatic Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319404/
  7. Jul 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CAF-mediated regulation of prostate cancer stem cell stemness via the Wnt/β-catenin and SDF-1/CXCR4 pathways in castration-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12303950/
  9. www.science.org www.science.org
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12260511/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery and Biosynthesis of Nyuzenamides D and E by Genome Mining in
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    pmc.ncbi.nlm.nih.gov/articles/PMC12224093/
  12. Jun 2025
  13. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Ezetimibe Engineered L14-8 Suppresses Advanced Prostate Cancer by Activating PLK1/TP53-SAT1-Induced Ferroptosis
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    advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202504192
  14. pubs.acs.org pubs.acs.org
    Pepticinnamins N, O, and P, Nonribosomal Peptides from the Soil-Derived Streptomyces mirabilis P8-A2
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    pubs.acs.org/doi/full/10.1021/acs.jnatprod.4c00029
  15. May 2025
  16. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70065
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Emerin Dysregulation Drives the Very-Small-Nuclear Phenotype and Lineage Plasticity That Associate with a Clinically Aggressive Subtype of Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12079098/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12017310/
  19. elifesciences.org elifesciences.org
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    elifesciences.org/reviewed-preprints/106511
  20. Apr 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11870442/
  22. www.sciencedirect.com www.sciencedirect.com
    Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer
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    sciencedirect.com/science/article/pii/S0925443925000675
  23. Mar 2025
  24. www.sciencedirect.com www.sciencedirect.com
    Lipid-metabolism-focused CRISPR screens identify enzymes of the mevalonate pathway as essential for prostate cancer growth
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    sciencedirect.com/science/article/pii/S2211124725002414
  25. www.cell.com www.cell.com
    Small-molecule RNA therapeutics to target prostate cancer
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    cell.com/cancer-cell/abstract/S1535-6108(25)00079-0
  26. Jan 2025
  27. www.sciencedirect.com www.sciencedirect.com
    Reciprocal regulation between DNMT3A/3B and microRNAs miRs-299-3p/-30e is a causal factor for the downregulation of microRNAs targeting Androgen Receptor in prostate cancer.
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    sciencedirect.com/science/article/pii/S2405844025003287
  28. Dec 2024
  29. 52.53.155.43 52.53.155.43
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  31. Nov 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11579030/
  33. Sep 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Integrative identification of non-coding regulatory regions driving metastatic prostate cancer
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    sciencedirect.com/science/article/pii/S221112472401115X
  35. aacrjournals.org aacrjournals.org
    Squalene epoxidase metabolic dependency is a targetable vulnerability in castration-resistant prostate cancer
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    aacrjournals.org/cancerres/article/82/17/3032/708286/Squalene-Epoxidase-Metabolic-Dependency-Is-a
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    PLXNA1 confers enzalutamide resistance in prostate cancer via AKT signaling pathway
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    sciencedirect.com/science/article/pii/S1476558624000897
  37. Aug 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Engineered Drug 3′UTRMYC1-18 Degrades the c-MYC-STAT5A/B-PD-L1 Complex In Vivo to Inhibit Metastatic Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11311709/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  40. 52.53.155.43 52.53.155.43
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    52.53.155.43/5ae378afd9ab5ca0cc44c821394ffd9a004fa694/Molecular Oncology - 2023 - Celada-html.html
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    52.53.155.43/908848ce9212d2a4c8be94b24c71e399d1f50f03/Molecular Oncology - 2023 - Ito-html.html
  42. Jul 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841372/
  44. Apr 2024
  45. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  46. Mar 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    sciencedirect.com/science/article/pii/S2451945624000874
  48. Feb 2024
  49. 52.53.155.43 52.53.155.43
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGFBP3 Promotes Resistance to Olaparib via Modulating EGFR Signaling in Advanced Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10847745/
  51. Dec 2023
  52. www.sciencedirect.com www.sciencedirect.com
    AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression
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    sciencedirect.com/science/article/pii/S2589004223026007
  53. Nov 2023
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent targeting of HDAC and PI3K to overcome phenotypic heterogeneity of castration-resistant and neuroendocrine prostate cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10658857/
  55. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of the Cyclin K-CDK12 complex induces DNA damage and increases the effect of androgen deprivation therapy in prostate cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34778
  56. Oct 2023
  57. link.springer.com link.springer.com
    Impact of sequencing of androgen receptor-signaling inhibition and radiotherapy in prostate cancer: importance of homologous recombination disruption
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    link.springer.com/article/10.1007/s00345-023-04649-9
  58. Aug 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The long transcript of lncRNA TMPO-AS1 promotes bone metastases of prostate cancer by regulating the CSNK2A1/DDX3X complex in Wnt/β-catenin signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10403548/
  60. 52.53.155.43 52.53.155.43
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    52.53.155.43/5ae378afd9ab5ca0cc44c821394ffd9a004fa694/Molecular Oncology - 2023 - Celada-html.html
  61. Apr 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10108886/
  63. Feb 2023
  64. 52.53.155.43 52.53.155.43
    Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy
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    52.53.155.43/4748dcb0d6edc0bb2ae04943a705118688f18f21/Intl Journal of Cancer - 2023 - Klusa - Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients-html.html
  65. Jan 2023
  66. aacrjournals.org aacrjournals.org
    Subtype and site specific-induced metabolic vulnerabilities in prostate cancer
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    aacrjournals.org/mcr/article/21/1/51/711791/Subtype-and-Site-Specific-Induced-Metabolic
  67. Dec 2022
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9770512/
  69. aacrjournals.org aacrjournals.org
    IL-1β expression driven by androgen receptor absence or inactivation promotes prostate cancer bone metastasis
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    aacrjournals.org/cancerrescommun/article/2/12/1545/711358/IL1-Expression-Driven-by-Androgen-Receptor-Absence
  70. 52.53.155.43 52.53.155.43
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  71. Oct 2022
  72. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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    elifesciences.org/articles/81083
  73. Aug 2022
  74. 52.53.155.43 52.53.155.43
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of Olaparib-Resistance Prostate Cancer Cell Lines to Identify Mechanisms Associated with Acquired Resistance
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    ncbi.nlm.nih.gov/pmc/articles/PMC9405809/
  76. Jun 2022
  77. www.sciencedirect.com www.sciencedirect.com
    A small-molecule Skp1 inhibitor elicits cell death by p53-dependent mechanism
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    sciencedirect.com/science/article/pii/S258900422200863X
  78. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Anti-cancer function of microRNA-30e is mediated by negative regulation of HELLPAR, a noncoding macroRNA, and genes involved in ubiquitination and cell cycle progression in prostate cancer
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13255
  79. aacrjournals.org aacrjournals.org
    Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers
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    aacrjournals.org/mcr/article/20/6/841/699055/Attenuating-Adaptive-VEGF-A-and-IL8-Signaling
  80. Nov 2021
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BP1 inhibits Cul3SPOP to amplify AR signaling and promote prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8602290/
  82. May 2021
  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA PAINT is Associated with Aggressive Prostate Cancer and Dysregulation of Cancer Hallmark Genes
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33569
  84. Apr 2021
  85. www.sciencedirect.com www.sciencedirect.com
    Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers
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    sciencedirect.com/science/article/pii/S0092867420308746
  86. Jan 2021
  87. www.nature.com www.nature.com
    KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer
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    nature.com/articles/s41419-020-03354-4
  88. Jan 2020
  89. www.sciencedirect.com www.sciencedirect.com
    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
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    sciencedirect.com/science/article/pii/S1535610819300522