22 Matching Annotations
  1. Mar 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A comprehensive functional atlas of ALK kinase domain variants reveals resistance landscape to ALK inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12958575/
  3. Feb 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical Characteristics and Spatial Transcriptome Analysis of Non–Small Cell Lung Cancers Exhibiting Early Alectinib Resistance: A Retrospective OLCSG Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877432/
  5. Jul 2025
  6. www.sciencedirect.com www.sciencedirect.com
    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    sciencedirect.com/science/article/pii/S1535610825002612
  7. Jun 2025
  8. link.springer.com link.springer.com
    Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis
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    link.springer.com/article/10.1186/s40170-025-00400-7
  9. Apr 2025
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11977641/
  11. Mar 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
    1
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    sciencedirect.com/science/article/pii/S1097276525001947
  13. Feb 2025
  14. ar.iiarjournals.org ar.iiarjournals.org
    ALK Inhibitor and Chemotherapy Combinations in Models of ALK-Translocated NSCLC
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    ar.iiarjournals.org/content/44/7/2805
  15. Sep 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AXL and SHC1 confer crizotinib resistance in patient-derived xenograft model of ALK-driven lung cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416680/
  17. Mar 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Silibinin is a suppressor of the metastasis-promoting transcription factor ID3
    1
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    sciencedirect.com/science/article/pii/S0944711324001570
  19. Nov 2023
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34783
  21. Jun 2023
  22. www.nature.com www.nature.com
    Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
    1
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    nature.com/articles/s41467-023-39241-7
  23. www.sciencedirect.com www.sciencedirect.com
    MEK inhibitor and anti-EGFR antibody overcome sotorasib resistance signals and enhance its antitumor effect in colorectal cancer cells
    1
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    sciencedirect.com/science/article/pii/S030438352300215X
  24. Apr 2022
  25. link.springer.com link.springer.com
    Integrated analysis of ALK higher expression in human cancer and downregulation in LUAD using RNA molecular scissors
    1
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    link.springer.com/article/10.1007/s12094-022-02835-6
  26. Oct 2021
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A MET-PTPRK kinase-phosphatase rheostat controls ZNRF3 and Wnt signaling
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8516413/
  28. Sep 2021
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silibinin Suppresses Tumor Cell-Intrinsic Resistance to Nintedanib and Enhances Its Clinical Activity in Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8394850/
  30. Aug 2021
  31. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
    1
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    sciencedirect.com/science/article/pii/S2451945619304015
  32. Jul 2021
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Radioresistance of KRAS/TP53‐Mutated Lung Cancer can be overcome by Radiation Dose Escalation or EGFR Tyrosine Kinase Inhibition In Vivo
    1
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32598
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC3566312/
  35. Sep 2020
  36. www.sciencedirect.com www.sciencedirect.com
    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    sciencedirect.com/science/article/pii/S2211124720308214
  37. www.sciencedirect.com www.sciencedirect.com
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    sciencedirect.com/science/article/pii/S1535610819305768
  38. Nov 2018
  39. www.sciencedirect.com www.sciencedirect.com
    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    sciencedirect.com/science/article/pii/S1074761318304357
  40. Nov 2017
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC3566312/