83 Matching Annotations
  1. Jun 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modeling the role of urokinase-type plasminogen activator, uPA, and circulating cancer-associated fibroblasts (cCAFs) in breast cancer cell extravasation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13233632/
  3. May 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repurposing Quetiapine as an Adjuvant Therapeutic Agent for Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13180434/
  5. Apr 2026
  6. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Ligand Electronics Dictate Geometry, Stability, and Cancer Cell Toxicity in Carbon-Stabilized Gold(III) Macrocycles
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    chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/cbic.202500962
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metastasis-associated wound repair promotes reciprocal lung epithelium activation and breast cancer metastatic outgrowth
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    pmc.ncbi.nlm.nih.gov/articles/PMC13051055/
  8. Mar 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The discovery and characterization of HBS-101, a novel inhibitor of midkine, as a therapeutic agent for the treatment of triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12353485/
  10. Feb 2026
  11. 54.241.53.176 54.241.53.176
    s12943-026-02568-y_reference-html.html
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    54.241.53.176/92be19b4f61904d1ecf98242923e8c19fc11bb5f/s12943-026-02568-y_reference-html.html
  12. www.nature.com www.nature.com
    Targeting the USP7-PRMT6 epigenetic axis overcomes chemoresistance in breast cancer by coordinating H3R2me2a deposition and RNF168 methylation for DNA repair and ferroptosis blockade
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    nature.com/articles/s41418-026-01672-2
  13. Jan 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Three-Dimensional Tumor Spheroids Reveal B7-H3 CAR T Cell Infiltration Dynamics and Microenvironment-Induced Functional Reprogramming in Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12839577/
  15. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Lipid Droplet-Localized Spindle Apparatus Coiled-Coil Protein 1 Regulates Lipid Droplet Distribution
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511960
  16. Nov 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrative proteogenomics and forward genetics reveals a novel mitotic vulnerability in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12641601/
  18. Sep 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCDHGB7 inhibits the progression of triple‐negative breast cancer by suppressing XRCC5/MYC‐mediated ribosome biogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12405659/
  20. www.sciencedirect.com www.sciencedirect.com
    Dual Inhibition of Carbonic Anhydrase IX and Glutathione Peroxidase 4 as a Novel Strategy for Ferroptosis-Induced Tumor Cell Death
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    sciencedirect.com/science/article/pii/S0223523425008724
  21. Aug 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TBK1 Targeting is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790382/
  23. Jul 2025
  24. www.sciencedirect.com www.sciencedirect.com
    Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis
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    sciencedirect.com/science/article/pii/S2666379125003258
  25. Jun 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EndoMAP.v1 charts the structural landscape of human early endosome complexes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12222028/
  27. www.sciencedirect.com www.sciencedirect.com
    Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer
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    sciencedirect.com/science/article/pii/S2451945625001655
  28. May 2025
  29. www.sciencedirect.com www.sciencedirect.com
    Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors
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    sciencedirect.com/science/article/pii/S0092867425005112
  30. www.sciencedirect.com www.sciencedirect.com
    Oncogenic HNF4α inhibits ferroptotic cell death through activating SLC7A11 by recruiting p300/CBP in breast cancer
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    sciencedirect.com/science/article/pii/S0925443925002327
  31. Apr 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor–Initiating Cells Characterized by IFN/STAT1 Activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11997551/
  33. Feb 2025
  34. aacrjournals.org aacrjournals.org
    Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer
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    aacrjournals.org/cancerres/article/84/21/3556/749280/Targeting-YES1-Disrupts-Mitotic-Fidelity-and
  35. Jan 2025
  36. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17437
  37. Dec 2024
  38. www.nature.com www.nature.com
    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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    nature.com/articles/s41418-024-01439-7
  39. Sep 2024
  40. www.sciencedirect.com www.sciencedirect.com
    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    sciencedirect.com/science/article/pii/S2589004224020844
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nanodynamo quantifies subcellular RNA dynamics revealing extensive coupling between steps of the RNA life cycle
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    ncbi.nlm.nih.gov/pmc/articles/PMC11375098/
  42. Aug 2024
  43. www.molbiolcell.org www.molbiolcell.org
    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells | Molecular Biology of the Cell
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    molbiolcell.org/doi/abs/10.1091/mbc.E18-05-0282
  44. www.molbiolcell.org www.molbiolcell.org
    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells | Molecular Biology of the Cell
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    molbiolcell.org/doi/full/10.1091/mbc.E18-05-0282
  45. May 2024
  46. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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    nature.com/articles/s41416-024-02697-5
  47. www.science.org www.science.org
    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    science.org/doi/10.1126/scisignal.adh4475
  48. www.sciencedirect.com www.sciencedirect.com
    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    sciencedirect.com/science/article/pii/S2666379124002441
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  50. Apr 2024
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  52. www.sciencedirect.com www.sciencedirect.com
    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124001733
  53. Mar 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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    sciencedirect.com/science/article/pii/S2211124724003000
  55. Feb 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PLK4 as a potential target to enhance radiosensitivity in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10873955/
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34859
  58. Jan 2024
  59. www.sciencedirect.com www.sciencedirect.com
    SPOP negatively regulates mTORC1 activity by ubiquitinating Sec13
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    sciencedirect.com/science/article/pii/S0898656824000287
  60. Dec 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10683240/
  62. Oct 2023
  63. www.mdpi.com www.mdpi.com
    ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
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    mdpi.com/1422-0067/24/19/14566
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10552894/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543979/
  66. Aug 2023
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The 3′ Non-Coding Sequence Negatively Regulates PD-L1 Expression, and Its Regulators Are Systematically Identified in Pan-Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10454350/
  68. Jul 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10368911/
  70. May 2023
  71. www.sciencedirect.com www.sciencedirect.com
    Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through a ROS-dependent mechanism
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    sciencedirect.com/science/article/pii/S2589004223008659
  72. Mar 2023
  73. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor-alpha protein in breast cancer cells
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13399
  74. www.sciencedirect.com www.sciencedirect.com
    Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
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    sciencedirect.com/science/article/pii/S2211124723001754
  75. Dec 2022
  76. www.sciencedirect.com www.sciencedirect.com
    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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    sciencedirect.com/science/article/pii/S2211124722016424
  77. Nov 2022
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9648413/
  79. www.sciencedirect.com www.sciencedirect.com
    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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    sciencedirect.com/science/article/pii/S2211124722015467
  80. Oct 2022
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Link Between Glucose Metabolism and EMT Drives Triple Negative Breast Cancer Migratory Heterogeneity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9579510/
  82. Sep 2022
  83. www.sciencedirect.com www.sciencedirect.com
    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379122002907
  84. Jul 2022
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NPC1 Confers Metabolic Flexibility in Triple Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9319388/
  86. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
  87. May 2022
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane
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    ncbi.nlm.nih.gov/pmc/articles/PMC9122495/
  89. Apr 2022
  90. www.sciencedirect.com www.sciencedirect.com
    Genome-wide RNA interference screen in cancer stem cells
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    sciencedirect.com/science/article/pii/S0091679X22000255
  91. Mar 2022
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unlabeled aspirin as an activatable theranostic MRI agent for breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8825591/
  93. Jan 2022
  94. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A modular platform for automated cryo-FIB workflows
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    pmc.ncbi.nlm.nih.gov/articles/PMC8769651/
  95. Nov 2021
  96. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity
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    sciencedirect.com/science/article/pii/S258900422101292X
  97. Aug 2021
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5726799/
  99. www.cell.com www.cell.com
    Untitled document
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    cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6232964/
  101. elifesciences.org elifesciences.org
    Seipin is required for converting nascent to mature lipid droplets
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    elifesciences.org/articles/16582
  102. www.sciencedirect.com www.sciencedirect.com
    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S2405471219303874
  103. Jul 2021
  104. www.sciencedirect.com www.sciencedirect.com
    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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    sciencedirect.com/science/article/pii/S1097276519300565
  105. www.sciencedirect.com www.sciencedirect.com
    The Cancer SENESCopedia: A delineation of cancer cell senescence
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    sciencedirect.com/science/article/pii/S2211124721008585
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
  107. Jun 2021
  108. www.sciencedirect.com www.sciencedirect.com
    Oncogene-regulated release of extracellular vesicles
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    sciencedirect.com/science/article/pii/S1534580721004433
  109. www.nature.com www.nature.com
    MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
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    nature.com/articles/s41523-021-00273-1
  110. May 2021
  111. www.sciencedirect.com www.sciencedirect.com
    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
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    sciencedirect.com/science/article/pii/S1097276521003579
  112. www.sciencedirect.com www.sciencedirect.com
    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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    sciencedirect.com/science/article/pii/S1550413121000577
  113. Feb 2021
  114. academic.oup.com academic.oup.com
    A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-Negative Breast Cancer Anoikis Resistance
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    academic.oup.com/endo/article/162/2/bqaa226/6027912
  115. Oct 2020
  116. www.cell.com www.cell.com
    Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
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    cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
  117. Sep 2020
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7302877/
  119. www.sciencedirect.com www.sciencedirect.com
    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719317139
  120. www.sciencedirect.com www.sciencedirect.com
    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
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    sciencedirect.com/science/article/pii/S0092867420306863
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FGF13 promotes metastasis of triple‐negative breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32874
  122. Jan 2020
  123. www.sciencedirect.com www.sciencedirect.com
    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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    sciencedirect.com/science/article/pii/S2451945619301746
  124. www.sciencedirect.com www.sciencedirect.com
    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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    sciencedirect.com/science/article/pii/S1097276519300565
  125. Nov 2018
  126. www.molbiolcell.org www.molbiolcell.org
    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells | Molecular Biology of the Cell
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    molbiolcell.org/doi/full/10.1091/mbc.E18-05-0282
  127. www.sciencedirect.com www.sciencedirect.com
    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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    sciencedirect.com/science/article/pii/S009286741831033X
  128. www.sciencedirect.com www.sciencedirect.com
    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1534580717308717
  129. Nov 2017
  130. elifesciences.org elifesciences.org
    Seipin is required for converting nascent to mature lipid droplets
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    elifesciences.org/articles/16582