82 Matching Annotations
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    Repurposing Quetiapine as an Adjuvant Therapeutic Agent for Triple-Negative Breast Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13180434/
  3. Apr 2026
  4. chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com
    Ligand Electronics Dictate Geometry, Stability, and Cancer Cell Toxicity in Carbon-Stabilized Gold(III) Macrocycles
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    Metastasis-associated wound repair promotes reciprocal lung epithelium activation and breast cancer metastatic outgrowth
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  6. Mar 2026
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    The discovery and characterization of HBS-101, a novel inhibitor of midkine, as a therapeutic agent for the treatment of triple negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12353485/
  8. Feb 2026
  9. 54.241.53.176 54.241.53.176
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    Targeting the USP7-PRMT6 epigenetic axis overcomes chemoresistance in breast cancer by coordinating H3R2me2a deposition and RNF168 methylation for DNA repair and ferroptosis blockade
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  11. Jan 2026
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    Three-Dimensional Tumor Spheroids Reveal B7-H3 CAR T Cell Infiltration Dynamics and Microenvironment-Induced Functional Reprogramming in Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12839577/
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    Lipid Droplet-Localized Spindle Apparatus Coiled-Coil Protein 1 Regulates Lipid Droplet Distribution
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202511960
  14. Nov 2025
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    Integrative proteogenomics and forward genetics reveals a novel mitotic vulnerability in triple-negative breast cancer
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  16. Sep 2025
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    PCDHGB7 inhibits the progression of triple‐negative breast cancer by suppressing XRCC5/MYC‐mediated ribosome biogenesis
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    Dual Inhibition of Carbonic Anhydrase IX and Glutathione Peroxidase 4 as a Novel Strategy for Ferroptosis-Induced Tumor Cell Death
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    sciencedirect.com/science/article/pii/S0223523425008724
  19. Aug 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TBK1 Targeting is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids
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    pmc.ncbi.nlm.nih.gov/articles/PMC11790382/
  21. Jul 2025
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    Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis
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  23. Jun 2025
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    EndoMAP.v1 charts the structural landscape of human early endosome complexes
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    Mechanism by which the molecular glue-like verteporfin induces IRE1α dimerization and activation to synergize with AKT inhibition in breast cancer
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  26. May 2025
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    Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors
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    Oncogenic HNF4α inhibits ferroptotic cell death through activating SLC7A11 by recruiting p300/CBP in breast cancer
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    sciencedirect.com/science/article/pii/S0925443925002327
  29. Apr 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lineage Tracing and Single-Cell RNA Sequencing Reveal a Common Transcriptional State in Breast Cancer Tumor–Initiating Cells Characterized by IFN/STAT1 Activity
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  31. Feb 2025
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    Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple-Negative Breast Cancer
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  33. Jan 2025
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  35. Dec 2024
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    Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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  37. Sep 2024
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    Computational pipeline predicting cell death suppressors as targets for cancer therapy
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    Nanodynamo quantifies subcellular RNA dynamics revealing extensive coupling between steps of the RNA life cycle
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  40. Aug 2024
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    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells | Molecular Biology of the Cell
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    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells | Molecular Biology of the Cell
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  43. May 2024
  44. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
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    eEF1A2 promotes PTEN-GSK3β-SCF complex-dependent degradation of Aurora kinase A and is inactivated in breast cancer
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    Inhibition of protein translational machinery in triple-negative breast cancer as a promising therapeutic strategy
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    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063688/
  48. Apr 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer
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  51. Mar 2024
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    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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  53. Feb 2024
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    PLK4 as a potential target to enhance radiosensitivity in triple-negative breast cancer
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    SAA1-dependent reprogramming of adipocytes by tumor cells is associated with triple negative breast cancer aggressiveness
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.34859
  56. Jan 2024
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    SPOP negatively regulates mTORC1 activity by ubiquitinating Sec13
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  58. Dec 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Key regulator PNPLA8 drives phospholipid reprogramming induced proliferation and migration in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10683240/
  60. Oct 2023
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    ETHE1 Accelerates Triple-Negative Breast Cancer Metastasis by Activating GCN2/eIF2α/ATF4 Signaling
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    mdpi.com/1422-0067/24/19/14566
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    Functional inhibition of the RNA‐binding protein HuR sensitizes triple‐negative breast cancer to chemotherapy
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    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
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  64. Aug 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The 3′ Non-Coding Sequence Negatively Regulates PD-L1 Expression, and Its Regulators Are Systematically Identified in Pan-Cancer
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  66. Jul 2023
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    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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  68. May 2023
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    Enhanced mitochondrial fission inhibits triple-negative breast cancer cell migration through a ROS-dependent mechanism
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  70. Mar 2023
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    Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor-alpha protein in breast cancer cells
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    Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
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  73. Dec 2022
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    The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC
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    sciencedirect.com/science/article/pii/S2211124722016424
  75. Nov 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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    Estrone, the major postmenopausal estrogen, binds ERa to induce SNAI2, epithelial-to-mesenchymal transition, and ER+ breast cancer metastasis
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  78. Oct 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Link Between Glucose Metabolism and EMT Drives Triple Negative Breast Cancer Migratory Heterogeneity
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  80. Sep 2022
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    PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer
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  82. Jul 2022
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NPC1 Confers Metabolic Flexibility in Triple Negative Breast Cancer
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  84. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
  85. May 2022
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    Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane
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    ncbi.nlm.nih.gov/pmc/articles/PMC9122495/
  87. Apr 2022
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    Genome-wide RNA interference screen in cancer stem cells
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    sciencedirect.com/science/article/pii/S0091679X22000255
  89. Mar 2022
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    Unlabeled aspirin as an activatable theranostic MRI agent for breast cancer
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  91. Jan 2022
  92. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A modular platform for automated cryo-FIB workflows
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  93. Nov 2021
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    Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity
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  95. Aug 2021
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    cell.com/developmental-cell/abstract/S1534-5807(17)30871-7
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    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6232964/
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    Seipin is required for converting nascent to mature lipid droplets
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    elifesciences.org/articles/16582
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    Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells
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    sciencedirect.com/science/article/pii/S2405471219303874
  101. Jul 2021
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    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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    The Cancer SENESCopedia: A delineation of cancer cell senescence
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
  105. Jun 2021
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    Oncogene-regulated release of extracellular vesicles
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  107. www.nature.com www.nature.com
    MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
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    nature.com/articles/s41523-021-00273-1
  108. May 2021
  109. www.sciencedirect.com www.sciencedirect.com
    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
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    Asparagine couples mitochondrial respiration to ATF4 activity and tumor growth
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  111. Feb 2021
  112. academic.oup.com academic.oup.com
    A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-Negative Breast Cancer Anoikis Resistance
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    academic.oup.com/endo/article/162/2/bqaa226/6027912
  113. Oct 2020
  114. www.cell.com www.cell.com
    Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing
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    cell.com/cell-chemical-biology/abstract/S2451-9456(20)30284-1
  115. Sep 2020
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7302877/
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    Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S2211124719317139
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    Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids
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    sciencedirect.com/science/article/pii/S0092867420306863
  119. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FGF13 promotes metastasis of triple‐negative breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32874
  120. Jan 2020
  121. www.sciencedirect.com www.sciencedirect.com
    Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity
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    sciencedirect.com/science/article/pii/S2451945619301746
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    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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  123. Nov 2018
  124. www.molbiolcell.org www.molbiolcell.org
    Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells | Molecular Biology of the Cell
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    molbiolcell.org/doi/full/10.1091/mbc.E18-05-0282
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    Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization
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  126. www.sciencedirect.com www.sciencedirect.com
    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer
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    sciencedirect.com/science/article/pii/S1534580717308717
  127. Nov 2017
  128. elifesciences.org elifesciences.org
    Seipin is required for converting nascent to mature lipid droplets
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    elifesciences.org/articles/16582