64 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Curcumol Induces Necroptosis of Hepatic Stellate Cells by Targeting KAT8 to Suppress HK2 Lactylation and Promote HUWE1-Dependent Ubiquitination
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    pmc.ncbi.nlm.nih.gov/articles/PMC12839083/
  3. Jan 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Insights into the Economic Toll of Cell Line Misidentification: A Comprehensive Review
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    pmc.ncbi.nlm.nih.gov/articles/PMC12821653/
  5. Dec 2025
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    CADD-engineered peptide protacs efficiently target PCSK9 for hypercholesterolemia in vivo
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    sciencedirect.com/science/article/pii/S0026049525003555
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    Reprogramming offspring liver health: maternal indole supplementation as a preventive strategy against MASLD
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    sciencedirect.com/science/article/pii/S2352396425005481
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    TFEB-driven autophagy enhancement via a ROS-triggered NIR-II nanoplatform for targeted non-alcoholic fatty liver disease therapy
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    sciencedirect.com:5037/science/article/pii/S1385894725128295
  9. Oct 2025
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    Syringin attenuates fibrogenesis and inflammation through SIRT3-regulated P2X7 receptor signaling pathway in hepatic fibrosis
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    sciencedirect.com/science/article/pii/S0944711325010980
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    Liver-Targeted Scutellarin Nanoemulsion Alleviates Fibrosis with Ancillary Modulation of the Gut–Liver Microbiota
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    pmc.ncbi.nlm.nih.gov/articles/PMC12524853/
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    Prorenin in Hepatic Stellate Cell Extracellular Vesicles Induces Platelet‐Dependent Thrombin Formation and Release of Profibrotic TGF‐β
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    pmc.ncbi.nlm.nih.gov/articles/PMC12521956/
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    Bio-fabrication of fibrotic liver microtissues as a scalable and drug-responsive in vitro model
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    sciencedirect.com/science/article/pii/S0378517325010798
  14. Sep 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive Genetic and Molecular Characterization Confirms Hepatic Stellate Cell Origin of the Immortal Col-GFP HSC Line
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    pmc.ncbi.nlm.nih.gov/articles/PMC12386721/
  16. Jun 2025
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    Calycosin limits hepatic fibrogenesis via KLF15 dependent repression of P2X7R in thioacetamide-induced hepatic fibrosis
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    sciencedirect.com/science/article/pii/S0378874125008839
  18. May 2025
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    Engineering a three-dimensional liver steatosis model
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    sciencedirect.com/science/article/pii/S0925443925002364
  20. Apr 2025
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    A Novel Mechanism of the p53 Isoform Δ40p53α in Regulating Collagen III Expression in TGFβ1-Induced LX-2 Human Hepatic Stellate Cells
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202403146RR
  22. Jan 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pemigatinib suppresses liver fibrosis and subsequent osteodystrophy in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11717528/
  24. Nov 2024
  25. pubs.acs.org pubs.acs.org
    Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling
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    pubs.acs.org/doi/10.1021/acs.jafc.4c03286
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    Eriocitrin ameliorates hepatic fibrosis and inflammation: The involvement of PPARα-mediated NLRP1/NLRC4 inflammasome signaling cascades
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    sciencedirect.com/science/article/pii/S0378874124014181
  27. Aug 2024
  28. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    GSK805 inhibits alpha-smooth muscle expression and modulates liver inflammation without impairing the well-being of mice
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202400733R
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    Raspberry Ketone Attenuates Hepatic Fibrogenesis and Inflammation via Regulating the Crosstalk of FXR and PGC-1α Signaling
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    pubs.acs.org/doi/10.1021/acs.jafc.4c03286
  30. Jul 2024
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    Identification and characterization of TM4SF1+ tumor self-seeded cells
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  32. Jun 2024
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gossypetin targets the liver-brain axis to alleviate pre-existing liver fibrosis and hippocampal neuroinflammation in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11163038/
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    Nicotine aggravates liver fibrosis via α7 nicotinic acetylcholine receptor expressed on activated hepatic stellate cells in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11155520/
  35. May 2024
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bioengineering scalable and drug-responsive in vitro human multicellular non-alcoholic fatty liver disease microtissues encapsulated in the liver extracellular matrix-derived hydrogel
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089098/
  37. Apr 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Albiflorin ameliorates thioacetamide-induced hepatic fibrosis: The involvement of NURR1-mediated inflammatory signaling cascades in hepatic stellate cells activation
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    The antiprotozoal drug nitazoxanide improves experimental liver fibrosis in mice
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    Virological response to nucleos(t)ide analogues treatment in chronic hepatitis B patients is associated with Bacteroides-dominant gut microbiome
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    sciencedirect.com/science/article/pii/S2352396424001361
  41. Feb 2024
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC10897550/
  43. Jan 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schizandrin C regulates lipid metabolism and inflammation in liver fibrosis by NF-κB and p38/ERK MAPK signaling pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10242051/
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    IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids
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    sciencedirect.com/science/article/pii/S2666379123005694
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intranasal Delivery of Oncolytic Adenovirus XVir-N-31 via Optimized Shuttle Cells Significantly Extends Survival of Glioblastoma-Bearing Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10605419/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10367116/
  48. Nov 2023
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618741/
  50. Oct 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Sesamol as a potential candidate for the treatment of hepatic fibrosis, based on its regulation of FXR/LXR axis-mediated inhibition of autophagy through crosstalk between hepatic cells and macrophage
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    Polyenylphosphatidylcholines as bioactive excipient in tablets for the treatment of liver fibrosis
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  54. Sep 2023
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  56. Jul 2023
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10367116/
  58. Jan 2023
  59. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15997
  60. Dec 2022
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    Physcion alleviates chronic alcoholic hepatic inflammation and pyroptosis through SIRT1-AMPK activation
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  62. Nov 2022
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    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2 Associated Cell Adhesion
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    ncbi.nlm.nih.gov/pmc/articles/PMC9635595/
  65. Sep 2022
  66. www.sciencedirect.com www.sciencedirect.com
    Salvianolic acid B suppresses hepatic stellate cell activation and liver fibrosis by inhibiting the NF-κB signaling pathway via miR-6499-3p/LncRNA-ROR
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    sciencedirect.com/science/article/pii/S0944711322005244
  67. Jul 2022
  68. www.nature.com www.nature.com
    Loss of FOCAD, operating via the SKI messenger RNA surveillance pathway, causes a pediatric syndrome with liver cirrhosis
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    nature.com/articles/s41588-022-01120-0
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiproliferative and Antimicrobial Effects of Rosmarinus officinalis L. Loaded Liposomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC9268459/
  70. Jun 2022
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  72. Mar 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A survey of optimal strategy for signature-based drug repositioning and an application to liver cancer
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    The in vitro and in vivo study of a pyrazole derivative, J-1063, as a novel anti-liver fibrosis agent: Synthesis, biological evaluation, and mechanistic analysis
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    sciencedirect.com/science/article/pii/S0045206822001201
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel HSF1 activator ameliorates nonalcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15727
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    Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus
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    sciencedirect.com/science/article/pii/S2352396422000871
  77. Dec 2021
  78. cancerimmunolres.aacrjournals.org cancerimmunolres.aacrjournals.org
    The Fibronectin–ILT3 Interaction Functions as a Stromal Checkpoint that Suppresses Myeloid Cells
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    cancerimmunolres.aacrjournals.org/content/9/11/1283
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    Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation
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    sciencedirect.com/science/article/pii/S2589004221014206
  80. Sep 2021
  81. www.mdpi.com www.mdpi.com
    Costunolide Loaded in pH-Responsive Mesoporous Silica Nanoparticles for Increased Stability and an Enhanced Anti-Fibrotic Effect
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    mdpi.com/1424-8247/14/10/951
  82. Aug 2021
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6316133/
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    Remodeling of hepatic stellate cells orchestrated the stroma-derived oxaliplatin-resistance through CCN3 paracrine in hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC6896671/
  85. Jul 2021
  86. www.sciencedirect.com www.sciencedirect.com
    Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule
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    sciencedirect.com/science/article/pii/S2211124719314901
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15490
  88. May 2021
  89. www.sciencedirect.com www.sciencedirect.com
    P2X7R orchestrates the progression of murine hepatic fibrosis by making a feedback loop from macrophage to hepatic stellate cells
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    sciencedirect.com/science/article/pii/S0378427420303416
  90. Mar 2021
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sulforaphane Inhibits the Expression of Long Noncoding RNA H19 and Its Target APOBEC3G and Thereby Pancreatic Cancer Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7920255/
  92. Feb 2021
  93. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  94. Jan 2021
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    Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia
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    sciencedirect.com/science/article/pii/S0092867420314550
  96. Dec 2020
  97. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Evidence for liver and peripheral immune cells secreting tumor-suppressive extracellular vesicles in melanoma patients
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  98. Sep 2020
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  100. Jan 2020
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  103. Nov 2017
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    Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes
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    sciencedirect.com/science/article/pii/S2352396417303614