40 Matching Annotations
  1. Last 7 days
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    A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation
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    sciencedirect.com/science/article/pii/S1097276525006513
  3. Jul 2025
  4. www.biorxiv.org www.biorxiv.org
    Mitotic slippage causes nuclear instability in polyploid cells
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    biorxiv.org/content/10.1101/2025.07.21.665898v1
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    The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA
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    elifesciences.org/articles/96414
  6. Jun 2025
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    The human testis-enriched HSPA2 interacts with HIF-1α in epidermal keratinocytes, yet HIF-1α stability and HIF-1-dependent gene expression rely on the HSPA (HSP70) activity
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    sciencedirect.com/science/article/pii/S0167488924000788
  8. May 2025
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70051
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    CDK4/6 activity is required during G2 arrest to prevent stress induced endoreplication
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    pmc.ncbi.nlm.nih.gov/articles/PMC11305671/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HSPA2 influences the differentiation and production of immunomodulatory mediators in human immortalized epidermal keratinocyte lines
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    pmc.ncbi.nlm.nih.gov/articles/PMC12033329/
  12. Apr 2025
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    Enhancing Form Stability: Shrink-Resistant Hydrogels Made of Interpenetrating Networks of Recombinant Spider Silk and Collagen-I
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adhm.202500311
  14. Mar 2025
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    The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis
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    sciencedirect.com/science/article/pii/S2211124725001743
  16. Feb 2025
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    Ultrasound-assisted synthesis of new bisphosphonate–betulin conjugates and preliminary evaluation of their cytotoxic activity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11800102/
  18. Jan 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chromosome mis-segregation triggers cell cycle arrest through a mechanosensitive nuclear envelope checkpoint
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    pmc.ncbi.nlm.nih.gov/articles/PMC11735390/
  20. Dec 2024
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    The histone H3.3 K27M mutation suppresses Ser31phosphorylation and mitotic fidelity, which can directly drive gliomagenesis
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    cell.com/current-biology/abstract/S0960-9822(24)01575-6
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    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
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    sciencedirect.com/science/article/pii/S2405471224003375
  23. Nov 2024
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  25. Sep 2024
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    A TBK1-independent primordial function of STING in lysosomal biogenesis
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    sciencedirect.com/science/article/pii/S1097276524007032
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    Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage
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    ncbi.nlm.nih.gov/pmc/articles/PMC11385192/
  28. Aug 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-loops and impaired autophagy trigger cGAS-dependent inflammation via micronuclei formation in Senataxin-deficient cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11335261/
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    Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11303508/
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    cGAS-activated endothelial cell–T cell cross-talk initiates tertiary lymphoid structure formation
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    science.org/doi/10.1126/sciimmunol.adk2612
  32. Jul 2024
  33. www.biorxiv.org www.biorxiv.org
    Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells
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    biorxiv.org/content/10.1101/2024.07.21.604463v1
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    The extracellular matrix integrates mitochondrial homeostasis
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    Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11199525/
  36. Jun 2024
  37. www.nature.com www.nature.com
    An intermediate Rb–E2F activity state safeguards proliferation commitment
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    nature.com/articles/s41586-024-07554-2
  38. May 2024
  39. www.biorxiv.org www.biorxiv.org
    Auranofin and reactive oxygen species inhibit protein synthesis and regulate the level of the PLK1 protein in Ewing sarcoma cells
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    biorxiv.org/content/10.1101/2024.05.13.593567v1
  40. www.science.org www.science.org
    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
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    science.org/doi/10.1126/science.adi2421
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
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    ncbi.nlm.nih.gov/pmc/articles/PMC11039982/
  42. Feb 2024
  43. www.mdpi.com www.mdpi.com
    Investigation of Staphylococcus aureus Biofilm-Associated Toxin as a Potential Squamous Cell Carcinoma Therapeutic
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    mdpi.com/2076-2607/12/2/293
  44. Jul 2023
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TP53 Induced Glycolysis and Apoptosis Regulator and Monocarboxylate Transporter 4 drive metabolic reprogramming with c-MYC and NFkB activation in breast cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.34660
  46. Jan 2023
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    Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain
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    mdpi.com/2073-4409/12/3/380
  48. Aug 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Chromatin-bound RB targets promoters, enhancers, and CTCF-bound loci and is redistributed by cell-cycle progression
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    sciencedirect.com/science/article/pii/S1097276522007109
  50. Apr 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic instability from a single S phase after whole-genome duplication
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    ncbi.nlm.nih.gov/pmc/articles/PMC8986533/
  52. Aug 2021
  53. www.sciencedirect.com www.sciencedirect.com
    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
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    sciencedirect.com/science/article/pii/S2211124718316838
  54. Jun 2021
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    Protocol for analysis of G2/M DNA synthesis in human cells
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    sciencedirect.com/science/article/pii/S266616672100277X
  56. May 2021
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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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    sciencedirect.com/science/article/pii/S009286742100502X
  58. Feb 2021
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    Persistence of RNA transcription during DNA replication delays duplication of transcription start sites until G2/M
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    sciencedirect.com/science/article/pii/S2211124721000723
  60. Sep 2020
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    Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis
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    sciencedirect.com/science/article/pii/S1550413120301881
  62. Nov 2018
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    Co-polymers of Actin and Tropomyosin Account for a Major Fraction of the Human Actin Cytoskeleton
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    sciencedirect.com/science/article/pii/S0960982218306894
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    Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dynamically Adjust Global DNA Synthesis Rates
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    sciencedirect.com/science/article/pii/S2405471218302291
  65. Nov 2017
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    Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion
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    sciencedirect.com/science/article/pii/S1097276516308528