22 Matching Annotations
  1. Mar 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AI-based discovery and cryoEM structural elucidation of a KATP channel pharmacochaperone
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    pmc.ncbi.nlm.nih.gov/articles/PMC11942174/
  3. Sep 2024
  4. www.biorxiv.org www.biorxiv.org
    Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes
    1
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    biorxiv.org/content/10.1101/2024.09.18.613649v1
  5. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Sodium butyrate prevents cytokine-induced β-cell dysfunction through restoration of stromal interaction molecule 1 expression and activation of store-operated calcium entry
    1
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302501RR
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11410534/
  7. Dec 2023
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone Deacetylase Inhibitors Prevent Cytokine-Induced β Cell Dysfunction Through Restoration of Stromal Interaction Molecule 1 Expression and Activation of Store-Operated Calcium Entry
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    ncbi.nlm.nih.gov/pmc/articles/PMC10723426/
  9. Oct 2023
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal Interaction Molecule 1 Maintains β-Cell Identity and Function in Female Mice Through Preservation of G-Protein–Coupled Estrogen Receptor 1 Signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10545557/
  11. May 2023
  12. www.sciencedirect.com www.sciencedirect.com
    Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells
    1
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    sciencedirect.com/science/article/pii/S2211124723005405
  13. Mar 2023
  14. link.springer.com link.springer.com
    Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice
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    link.springer.com/article/10.1007/s00125-023-05900-z
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual Role of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 in Inflammasome and Pancreatic β-Cell Function
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10002854/
  16. Jan 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Local PI(4,5)P2 signaling inhibits fusion pore expansion during exocytosis
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    sciencedirect.com/science/article/pii/S2211124723000475
  18. Aug 2021
  19. elifesciences.org elifesciences.org
    Untitled document
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    elifesciences.org/articles/24149
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6557626/
  21. www.sciencedirect.com www.sciencedirect.com
    Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates
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    sciencedirect.com/science/article/pii/S1097276519303648
  22. Jul 2021
  23. elifesciences.org elifesciences.org
    Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating
    1
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    elifesciences.org/content/6/e24149
  24. Mar 2021
  25. www.sciencedirect.com www.sciencedirect.com
    Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis
    1
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    sciencedirect.com/science/article/pii/S2211124721001443
  26. Sep 2020
  27. elifesciences.org elifesciences.org
    Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM
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    elifesciences.org/articles/31054
  28. Jan 2020
  29. www.sciencedirect.com www.sciencedirect.com
    Postnatal knockout of beta cell insulin receptor impaired insulin secretion in male mice exposed to high-fat diet stress
    1
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    sciencedirect.com/science/article/pii/S0303720719302904
  30. elifesciences.org elifesciences.org
    Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
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    elifesciences.org/articles/46417
  31. Nov 2018
  32. www.sciencedirect.com www.sciencedirect.com
    Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation
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    sciencedirect.com/science/article/pii/S1550413118305746
  33. academic.oup.com academic.oup.com
    SAD-A Promotes Glucose-stimulated Insulin Secretion through Phosphorylation and Inhibition of GDIα in Male Islet β-cells
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    academic.oup.com/endo/article/159/8/3036/5032632
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC5655142/
  35. Nov 2017
  36. elifesciences.org elifesciences.org
    Exophilin-8 assembles secretory granules for exocytosis in the actin cortex via interaction with RIM-BP2 and myosin-VIIa
    1
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    elifesciences.org/articles/26174